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Items: 1 to 50 of 281

1.

Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia.

Bansal V, Mitjans M, Burik CAP, Linnér RK, Okbay A, Rietveld CA, Begemann M, Bonn S, Ripke S, de Vlaming R, Nivard MG, Ehrenreich H, Koellinger PD.

Nat Commun. 2018 Aug 6;9(1):3078. doi: 10.1038/s41467-018-05510-z.

2.

Excitation-inhibition dysbalance as predictor of autistic phenotypes.

Oliveira B, Mitjans M, Nitsche MA, Kuo MF, Ehrenreich H.

J Psychiatr Res. 2018 Jun 2;104:96-99. doi: 10.1016/j.jpsychires.2018.06.004. [Epub ahead of print]

PMID:
30015265
3.

Convergence of placenta biology and genetic risk for schizophrenia.

Ursini G, Punzi G, Chen Q, Marenco S, Robinson JF, Porcelli A, Hamilton EG, Mitjans M, Maddalena G, Begemann M, Seidel J, Yanamori H, Jaffe AE, Berman KF, Egan MF, Straub RE, Colantuoni C, Blasi G, Hashimoto R, Rujescu D, Ehrenreich H, Bertolino A, Weinberger DR.

Nat Med. 2018 Jun;24(6):792-801. doi: 10.1038/s41591-018-0021-y. Epub 2018 May 28.

PMID:
29808008
4.

Violent aggression predicted by multiple pre-adult environmental hits.

Mitjans M, Seidel J, Begemann M, Bockhop F, Moya-Higueras J, Bansal V, Wesolowski J, Seelbach A, Ibáñez MI, Kovacevic F, Duvar O, Fañanás L, Wolf HU, Ortet G, Zwanzger P, Klein V, Lange I, Tänzer A, Dudeck M, Penke L, van Elst LT, Bittner RA, Schmidmeier R, Freese R, Müller-Isberner R, Wiltfang J, Bliesener T, Bonn S, Poustka L, Müller JL, Arias B, Ehrenreich H.

Mol Psychiatry. 2018 May 24. doi: 10.1038/s41380-018-0043-3. [Epub ahead of print]

PMID:
29795411
5.

Health technology assessment of public health interventions: an analysis of characteristics and comparison of methods-study protocol.

Mathes T, Willms G, Polus S, Stegbauer C, Messer M, Klingler C, Ehrenreich H, Niebuhr D, Marckmann G, Gerhardus A, Pieper D.

Syst Rev. 2018 May 23;7(1):79. doi: 10.1186/s13643-018-0743-4.

6.

Cognitive, emotional and social phenotyping of mice in an observer-independent setting.

Dere E, Ronnenberg A, Tampe B, Arinrad S, Schmidt M, Zeisberg E, Ehrenreich H.

Neurobiol Learn Mem. 2018 Apr;150:136-150. doi: 10.1016/j.nlm.2018.02.023. Epub 2018 Feb 21.

PMID:
29474958
7.

Autoantibodies against N-methyl-d-aspartate receptor 1 in health and disease.

Ehrenreich H.

Curr Opin Neurol. 2018 Jun;31(3):306-312. doi: 10.1097/WCO.0000000000000546.

8.

Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model.

Pan H, Oliveira B, Saher G, Dere E, Tapken D, Mitjans M, Seidel J, Wesolowski J, Wakhloo D, Klein-Schmidt C, Ronnenberg A, Schwabe K, Trippe R, Mätz-Rensing K, Berghoff S, Al-Krinawe Y, Martens H, Begemann M, Stöcker W, Kaup FJ, Mischke R, Boretius S, Nave KA, Krauss JK, Hollmann M, Lühder F, Ehrenreich H.

Mol Psychiatry. 2018 Feb 9. doi: 10.1038/s41380-017-0011-3. [Epub ahead of print]

PMID:
29426955
9.

A bloody brake on myelin repair.

Nave KA, Ehrenreich H.

Nature. 2018 Jan 4;553(7686):31-32. doi: 10.1038/d41586-017-08232-2. No abstract available.

PMID:
29300019
10.

Pursuing functional connectivity in NMDAR1 autoantibody carriers.

Oliveira B, Ehrenreich H.

Lancet Psychiatry. 2018 Jan;5(1):21-22. doi: 10.1016/S2215-0366(17)30465-0. No abstract available.

PMID:
29277208
11.

Microglia ablation alleviates myelin-associated catatonic signs in mice.

Janova H, Arinrad S, Balmuth E, Mitjans M, Hertel J, Habes M, Bittner RA, Pan H, Goebbels S, Begemann M, Gerwig UC, Langner S, Werner HB, Kittel-Schneider S, Homuth G, Davatzikos C, Völzke H, West BL, Reif A, Grabe HJ, Boretius S, Ehrenreich H, Nave KA.

J Clin Invest. 2018 Feb 1;128(2):734-745. doi: 10.1172/JCI97032. Epub 2017 Dec 18.

12.

Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer's Dementia in Individuals With Previous Depression.

Bartels C, Wagner M, Wolfsgruber S, Ehrenreich H, Schneider A; Alzheimer’s Disease Neuroimaging Initiative.

Am J Psychiatry. 2018 Mar 1;175(3):232-241. doi: 10.1176/appi.ajp.2017.17040404. Epub 2017 Nov 28.

PMID:
29179578
13.

„Hirn-Doping“: Erythropoietin zur Verbesserung kognitiver Leistung bei Mensch und Maus.

Ehrenreich H.

Drug Res (Stuttg). 2017 Nov;67(S 01):S14-S15. doi: 10.1055/s-0043-116529. Epub 2017 Oct 25. German. No abstract available.

PMID:
29069678
Free Article
14.

Sexual dimorphism of AMBRA1-related autistic features in human and mouse.

Mitjans M, Begemann M, Ju A, Dere E, Wüstefeld L, Hofer S, Hassouna I, Balkenhol J, Oliveira B, van der Auwera S, Tammer R, Hammerschmidt K, Völzke H, Homuth G, Cecconi F, Chowdhury K, Grabe H, Frahm J, Boretius S, Dandekar T, Ehrenreich H.

Transl Psychiatry. 2017 Oct 10;7(10):e1247. doi: 10.1038/tp.2017.213.

15.

How to pursue EPO in MS.

Bartels C, Ehrenreich H.

Mult Scler. 2018 Jul;24(8):1139-1140. doi: 10.1177/1352458517733132. Epub 2017 Oct 5. No abstract available.

16.

The Insect Ortholog of the Human Orphan Cytokine Receptor CRLF3 Is a Neuroprotective Erythropoietin Receptor.

Hahn N, Knorr DY, Liebig J, Wüstefeld L, Peters K, Büscher M, Bucher G, Ehrenreich H, Heinrich R.

Front Mol Neurosci. 2017 Jul 14;10:223. doi: 10.3389/fnmol.2017.00223. eCollection 2017.

17.

EV-3, an endogenous human erythropoietin isoform with distinct functional relevance.

Bonnas C, Wüstefeld L, Winkler D, Kronstein-Wiedemann R, Dere E, Specht K, Boxberg M, Tonn T, Ehrenreich H, Stadler H, Sillaber I.

Sci Rep. 2017 Jun 16;7(1):3684. doi: 10.1038/s41598-017-03167-0.

18.

A normal genetic variation modulates synaptic MMP-9 protein levels and the severity of schizophrenia symptoms.

Lepeta K, Purzycka KJ, Pachulska-Wieczorek K, Mitjans M, Begemann M, Vafadari B, Bijata K, Adamiak RW, Ehrenreich H, Dziembowska M, Kaczmarek L.

EMBO Mol Med. 2017 Aug;9(8):1100-1116. doi: 10.15252/emmm.201707723.

19.
20.

Autoantibodies against the N-Methyl-d-Aspartate Receptor Subunit NR1: Untangling Apparent Inconsistencies for Clinical Practice.

Ehrenreich H.

Front Immunol. 2017 Mar 1;8:181. doi: 10.3389/fimmu.2017.00181. eCollection 2017. Review.

21.

Hypersocial behavior and biological redundancy in mice with reduced expression of PSD95 or PSD93.

Winkler D, Daher F, Wüstefeld L, Hammerschmidt K, Poggi G, Seelbach A, Krueger-Burg D, Vafadari B, Ronnenberg A, Liu Y, Kaczmarek L, Schlüter OM, Ehrenreich H, Dere E.

Behav Brain Res. 2018 Oct 15;352:35-45. doi: 10.1016/j.bbr.2017.02.011. Epub 2017 Feb 9.

PMID:
28189758
22.

Neuroprotection and endocytosis: erythropoietin receptors in insect nervous systems.

Miljus N, Massih B, Weis MA, Rison JV, Bonnas CB, Sillaber I, Ehrenreich H, Geurten BR, Heinrich R.

J Neurochem. 2017 Apr;141(1):63-74. doi: 10.1111/jnc.13967. Epub 2017 Feb 28.

23.

OTTO: a new strategy to extract mental disease-relevant combinations of GWAS hits from individuals.

Ehrenreich H, Mitjans M, Van der Auwera S, Centeno TP, Begemann M, Grabe HJ, Bonn S, Nave KA.

Mol Psychiatry. 2018 Feb;23(2):476-486. doi: 10.1038/mp.2016.208. Epub 2016 Dec 6.

24.

Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms.

Schmitt A, Martins-de-Souza D, Akbarian S, Cassoli JS, Ehrenreich H, Fischer A, Fonteh A, Gattaz WF, Gawlik M, Gerlach M, Grünblatt E, Halene T, Hasan A, Hashimoto K, Kim YK, Kirchner SK, Kornhuber J, Kraus TFJ, Malchow B, Nascimento JM, Rossner M, Schwarz M, Steiner J, Talib L, Thibaut F, Riederer P, Falkai P; Members of the WFSBP Task Force on Biological Markers.

World J Biol Psychiatry. 2017 Aug;18(5):330-356. doi: 10.1080/15622975.2016.1224929. Epub 2016 Oct 26. Review.

PMID:
27782767
25.

The SocioBox: A Novel Paradigm to Assess Complex Social Recognition in Male Mice.

Krueger-Burg D, Winkler D, Mitkovski M, Daher F, Ronnenberg A, Schlüter OM, Dere E, Ehrenreich H.

Front Behav Neurosci. 2016 Aug 11;10:151. doi: 10.3389/fnbeh.2016.00151. eCollection 2016.

26.

All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class.

Castillo-Gómez E, Oliveira B, Tapken D, Bertrand S, Klein-Schmidt C, Pan H, Zafeiriou P, Steiner J, Jurek B, Trippe R, Prüss H, Zimmermann WH, Bertrand D, Ehrenreich H, Hollmann M.

Mol Psychiatry. 2017 Dec;22(12):1776-1784. doi: 10.1038/mp.2016.125. Epub 2016 Aug 9.

PMID:
27502473
27.

Cortical network dysfunction caused by a subtle defect of myelination.

Poggi G, Boretius S, Möbius W, Moschny N, Baudewig J, Ruhwedel T, Hassouna I, Wieser GL, Werner HB, Goebbels S, Nave KA, Ehrenreich H.

Glia. 2016 Nov;64(11):2025-40. doi: 10.1002/glia.23039. Epub 2016 Jul 29.

28.

Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning.

Tuoc T, Dere E, Radyushkin K, Pham L, Nguyen H, Tonchev AB, Sun G, Ronnenberg A, Shi Y, Staiger JF, Ehrenreich H, Stoykova A.

Mol Neurobiol. 2017 Aug;54(6):4618-4635. doi: 10.1007/s12035-016-9948-5. Epub 2016 Jul 8.

29.

Effects of erythropoietin on memory-relevant neurocircuitry activity and recall in mood disorders.

Miskowiak KW, Macoveanu J, Vinberg M, Assentoft E, Randers L, Harmer CJ, Ehrenreich H, Paulson OB, Knudsen GM, Siebner HR, Kessing LV.

Acta Psychiatr Scand. 2016 Sep;134(3):249-59. doi: 10.1111/acps.12597. Epub 2016 Jun 3.

PMID:
27259062
30.

Neural correlates of improved executive function following erythropoietin treatment in mood disorders.

Miskowiak KW, Vinberg M, Glerup L, Paulson OB, Knudsen GM, Ehrenreich H, Harmer CJ, Kessing LV, Siebner HR, Macoveanu J.

Psychol Med. 2016 Jun;46(8):1679-91. doi: 10.1017/S0033291716000209. Epub 2016 Mar 21.

PMID:
26996196
31.

Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus.

Hassouna I, Ott C, Wüstefeld L, Offen N, Neher RA, Mitkovski M, Winkler D, Sperling S, Fries L, Goebbels S, Vreja IC, Hagemeyer N, Dittrich M, Rossetti MF, Kröhnert K, Hannke K, Boretius S, Zeug A, Höschen C, Dandekar T, Dere E, Neher E, Rizzoli SO, Nave KA, Sirén AL, Ehrenreich H.

Mol Psychiatry. 2016 Dec;21(12):1752-1767. doi: 10.1038/mp.2015.212. Epub 2016 Jan 26.

32.

CD14 is a key organizer of microglial responses to CNS infection and injury.

Janova H, Böttcher C, Holtman IR, Regen T, van Rossum D, Götz A, Ernst AS, Fritsche C, Gertig U, Saiepour N, Gronke K, Wrzos C, Ribes S, Rolfes S, Weinstein J, Ehrenreich H, Pukrop T, Kopatz J, Stadelmann C, Salinas-Riester G, Weber MS, Prinz M, Brück W, Eggen BJ, Boddeke HW, Priller J, Hanisch UK.

Glia. 2016 Apr;64(4):635-49. doi: 10.1002/glia.22955. Epub 2015 Dec 18.

PMID:
26683584
33.

Selective expression of a constitutively active erythropoietin receptor in GABAergic neurons alters hippocampal network properties without affecting cognition.

Wüstefeld L, Winkler D, Janc OA, Hassouna I, Ronnenberg A, Ostmeier K, Müller M, Brose N, Ehrenreich H, Wojcik SM.

J Neurochem. 2016 Feb;136(4):698-705. doi: 10.1111/jnc.13445. Epub 2016 Jan 7.

34.

Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes.

Stepniak B, Kästner A, Poggi G, Mitjans M, Begemann M, Hartmann A, Van der Auwera S, Sananbenesi F, Krueger-Burg D, Matuszko G, Brosi C, Homuth G, Völzke H, Benseler F, Bagni C, Fischer U, Dityatev A, Grabe HJ, Rujescu D, Fischer A, Ehrenreich H.

EMBO Mol Med. 2015 Dec;7(12):1565-79. doi: 10.15252/emmm.201505696.

35.

The brain as immunoprecipitator of serum autoantibodies against N-Methyl-D-aspartate receptor subunit NR1.

Castillo-Gomez E, Kästner A, Steiner J, Schneider A, Hettling B, Poggi G, Ostehr K, Uhr M, Asif AR, Matzke M, Schmidt U, Pfander V, Hammer C, Schulz TF, Binder L, Stöcker W, Weber F, Ehrenreich H.

Ann Neurol. 2016 Jan;79(1):144-51. doi: 10.1002/ana.24545. Epub 2015 Dec 2.

PMID:
26505629
36.

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

Hammer M, Krueger-Burg D, Tuffy LP, Cooper BH, Taschenberger H, Goswami SP, Ehrenreich H, Jonas P, Varoqueaux F, Rhee JS, Brose N.

Cell Rep. 2015 Oct 20;13(3):516-523. doi: 10.1016/j.celrep.2015.09.011. Epub 2015 Oct 8.

37.

Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses.

Hammer C, Begemann M, McLaren PJ, Bartha I, Michel A, Klose B, Schmitt C, Waterboer T, Pawlita M, Schulz TF, Ehrenreich H, Fellay J.

Am J Hum Genet. 2015 Nov 5;97(5):738-43. doi: 10.1016/j.ajhg.2015.09.008. Epub 2015 Oct 8.

38.

Accumulated environmental risk determining age at schizophrenia onset: a deep phenotyping-based study.

Stepniak B, Papiol S, Hammer C, Ramin A, Everts S, Hennig L, Begemann M, Ehrenreich H.

Lancet Psychiatry. 2014 Nov;1(6):444-53. doi: 10.1016/S2215-0366(14)70379-7. Epub 2014 Nov 5.

PMID:
26361199
39.

Widespread expression of erythropoietin receptor in brain and its induction by injury.

Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, Stadler H, Kawabe H, Zimmermann WH, Nave KA, Schulz-Schaeffer W, Jahn O, Ehrenreich H.

Mol Med. 2015 Sep 1. doi: 10.2119/molmed.2015.00192. [Epub ahead of print]

40.

Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala.

Babaev O, Botta P, Meyer E, Müller C, Ehrenreich H, Brose N, Lüthi A, Krueger-Burg D.

Neuropharmacology. 2016 Jan;100:56-65. doi: 10.1016/j.neuropharm.2015.06.016. Epub 2015 Jun 30.

PMID:
26142252
41.

Dr Miskowiak and colleagues reply.

Miskowiak KW, Ehrenreich H, Kessing LV, Vinberg M.

J Clin Psychiatry. 2015 Jun;76(6):e835-6. doi: 10.4088/JCP.15lr09809a. No abstract available.

42.

Response to Letter Regarding Article, "Preexisting Serum Autoantibodies Against the NMDAR Subunit NR1 Modulate Evolution of Lesion Size in Acute Ischemic Stroke".

Castillo-Gomez E, Ehrenreich H.

Stroke. 2015 Jul;46(7):e178. doi: 10.1161/STROKEAHA.115.009725. Epub 2015 May 28. No abstract available.

PMID:
26022633
43.

Autism beyond diagnostic categories: characterization of autistic phenotypes in schizophrenia.

Kästner A, Begemann M, Michel TM, Everts S, Stepniak B, Bach C, Poustka L, Becker J, Banaschewski T, Dose M, Ehrenreich H.

BMC Psychiatry. 2015 May 13;15:115. doi: 10.1186/s12888-015-0494-x.

44.

Erythropoietin dampens injury-induced microglial motility.

Mitkovski M, Dahm L, Heinrich R, Monnheimer M, Gerhart S, Stegmüller J, Hanisch UK, Nave KA, Ehrenreich H.

J Cereb Blood Flow Metab. 2015 Aug;35(8):1233-6. doi: 10.1038/jcbfm.2015.100. Epub 2015 May 13.

45.

Healthcare providers' perceptions and self-reported fall prevention practices: findings from a large new york health system.

Smith ML, Stevens JA, Ehrenreich H, Wilson AD, Schuster RJ, Cherry CO, Ory MG.

Front Public Health. 2015 Apr 27;3:17. doi: 10.3389/fpubh.2015.00017. eCollection 2015.

46.

Preexisting Serum Autoantibodies Against the NMDAR Subunit NR1 Modulate Evolution of Lesion Size in Acute Ischemic Stroke.

Zerche M, Weissenborn K, Ott C, Dere E, Asif AR, Worthmann H, Hassouna I, Rentzsch K, Tryc AB, Dahm L, Steiner J, Binder L, Wiltfang J, Sirén AL, Stöcker W, Ehrenreich H.

Stroke. 2015 May;46(5):1180-6. doi: 10.1161/STROKEAHA.114.008323. Epub 2015 Mar 12.

PMID:
25765725
47.

A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity.

Hammer C, Wanitchakool P, Sirianant L, Papiol S, Monnheimer M, Faria D, Ousingsawat J, Schramek N, Schmitt C, Margos G, Michel A, Kraiczy P, Pawlita M, Schreiber R, Schulz TF, Fingerle V, Tumani H, Ehrenreich H, Kunzelmann K.

Mol Med. 2015 Feb 23;21:26-37. doi: 10.2119/molmed.2014.00219.

48.

Effects of Erythropoietin on Hippocampal Volume and Memory in Mood Disorders.

Miskowiak KW, Vinberg M, Macoveanu J, Ehrenreich H, Køster N, Inkster B, Paulson OB, Kessing LV, Skimminge A, Siebner HR.

Biol Psychiatry. 2015 Aug 15;78(4):270-7. doi: 10.1016/j.biopsych.2014.12.013. Epub 2014 Dec 18.

PMID:
25641635
49.

Fast cerebellar reflex circuitry requires synaptic vesicle priming by munc13-3.

Netrakanti PR, Cooper BH, Dere E, Poggi G, Winkler D, Brose N, Ehrenreich H.

Cerebellum. 2015 Jun;14(3):264-83. doi: 10.1007/s12311-015-0645-0.

50.

Autism as a disease of the synapse: search for mechanistic insight.

Ehrenreich H.

Springerplus. 2015 Jun 12;4(Suppl 1):L22. doi: 10.1186/2193-1801-4-S1-L22. eCollection 2015. No abstract available.

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