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Items: 1 to 50 of 264

1.

A nationwide genetic analysis of inherited retinal diseases in Israel as assessed by the Israeli inherited retinal disease consortium (IIRDC).

Sharon D, Ben-Yosef T, Goldenberg-Cohen N, Pras E, Gradstein L, Soudry S, Mezer E, Zur D, Abbasi AH, Zeitz C, Cremers FPM, Khan MI, Levy J, Rotenstreich Y, Birk OS, Ehrenberg M, Leibu R, Newman H, Shomron N, Banin E, Perlman I.

Hum Mutat. 2019 Aug 27. doi: 10.1002/humu.23903. [Epub ahead of print]

PMID:
31456290
2.

The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.

Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J.

Nat Commun. 2019 Jun 12;10(1):2579. doi: 10.1038/s41467-019-10608-z.

3.

The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation.

Holm M, Mandava CS, Ehrenberg M, Sanyal S.

Elife. 2019 Jun 7;8. pii: e46124. doi: 10.7554/eLife.46124.

4.

Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor.

Zukher I, Pavlov M, Tsibulskaya D, Kulikovsky A, Zyubko T, Bikmetov D, Serebryakova M, Nair SK, Ehrenberg M, Dubiley S, Severinov K.

MBio. 2019 Apr 30;10(2). pii: e00768-19. doi: 10.1128/mBio.00768-19.

5.

[THE ISRAELI INHERITED RETINAL DISEASES CONSORTIUM (IIRDC)- CLINICAL-GENETIC MAPPING AND FUTURE PERSPECTIVES].

Sharon D, Ben-Yosef T, Pras E, Goldenberg-Cohen N, Gradstein L, Shomron N, Birk O, Ehrenberg M, Levy J, Mezer E, Soudry S, Rotenstreich Y, Newman H, Leibu R, Banin E, Perlman I.

Harefuah. 2019 Feb;158(2):91-95. Hebrew.

PMID:
30779484
6.

Late diagnosis of Alstrom syndrome in a Yemenite-Jewish child.

Weiss S, Cohen L, Ben-Yosef T, Ehrenberg M, Goldenberg-Cohen N.

Ophthalmic Genet. 2019 Feb;40(1):7-11. doi: 10.1080/13816810.2018.1561900. Epub 2019 Jan 2.

PMID:
30600744
7.

Antibacterial and physical properties of a novel sonochemical-assisted Zn-CuO contact lens nanocoating.

Nahum Y, Israeli R, Mircus G, Perelshtein I, Ehrenberg M, Gutfreund S, Gedanken A, Bahar I.

Graefes Arch Clin Exp Ophthalmol. 2019 Jan;257(1):95-100. doi: 10.1007/s00417-018-4172-9. Epub 2018 Oct 27.

PMID:
30367291
8.

Evaluation of ocular motility deviation changes in exotropic patients after cycloplegic eye drops versus prism adaptation test.

Zahavi A, Friling R, Ron Y, Ehrenberg M, Nahum Y, Snir M.

Eur J Ophthalmol. 2019 Sep;29(5):482-485. doi: 10.1177/1120672118803518. Epub 2018 Oct 4.

PMID:
30284456
9.

Substrate-Induced Formation of Ribosomal Decoding Center for Accurate and Rapid Genetic Code Translation.

Pavlov MY, Ehrenberg M.

Annu Rev Biophys. 2018 May 20;47:525-548. doi: 10.1146/annurev-biophys-060414-034148. Review.

PMID:
29792818
10.

Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.

Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S, Ehrenberg M, Frank J.

Nucleic Acids Res. 2018 Jun 20;46(11):5861-5874. doi: 10.1093/nar/gky346.

11.

2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.

Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J, Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C, Ehrenberg M, Puglisi JD.

Nat Struct Mol Biol. 2018 Mar;25(3):208-216. doi: 10.1038/s41594-018-0030-z. Epub 2018 Feb 19.

12.

Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ ions.

Zhang J, Pavlov MY, Ehrenberg M.

Nucleic Acids Res. 2018 Feb 16;46(3):1362-1374. doi: 10.1093/nar/gkx1256.

13.

Horizontal Deviations in Congenital Brown Syndrome.

Dotan G, Eiger-Moscovich M, Snir M, Ehrenberg M, Friling R.

J Pediatr Ophthalmol Strabismus. 2018 Mar 1;55(2):113-116. doi: 10.3928/01913913-20171101-02. Epub 2017 Dec 19.

PMID:
29257185
14.

A conformational switch in initiation factor 2 controls the fidelity of translation initiation in bacteria.

Caban K, Pavlov M, Ehrenberg M, Gonzalez RL Jr.

Nat Commun. 2017 Nov 14;8(1):1475. doi: 10.1038/s41467-017-01492-6.

15.

Evolving multidimensional pharmacological approaches to CNV therapy in AMD.

Ehrenberg M, Benny O.

Curr Eye Res. 2018 Feb;43(2):147-154. doi: 10.1080/02713683.2017.1385088. Epub 2017 Nov 7. Review.

PMID:
29111834
16.

Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase.

Mellenius H, Ehrenberg M.

Nucleic Acids Res. 2017 Nov 16;45(20):11582-11593. doi: 10.1093/nar/gkx849.

17.

Ribosomes are optimized for autocatalytic production.

Reuveni S, Ehrenberg M, Paulsson J.

Nature. 2017 Jul 19;547(7663):293-297. doi: 10.1038/nature22998.

PMID:
28726822
18.

A recent intermezzo at the Ribosome Club.

Pavlov MY, Liljas A, Ehrenberg M.

Philos Trans R Soc Lond B Biol Sci. 2017 Mar 19;372(1716). pii: 20160185. doi: 10.1098/rstb.2016.0185. Review.

19.

Two proofreading steps amplify the accuracy of genetic code translation.

Ieong KW, Uzun Ü, Selmer M, Ehrenberg M.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13744-13749. Epub 2016 Nov 11.

20.

Key Intermediates in Ribosome Recycling Visualized by Time-Resolved Cryoelectron Microscopy.

Fu Z, Kaledhonkar S, Borg A, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J.

Structure. 2016 Dec 6;24(12):2092-2101. doi: 10.1016/j.str.2016.09.014. Epub 2016 Nov 3.

21.

Murine fundus fluorescein angiography: An alternative approach using a handheld camera.

Ehrenberg M, Ehrenberg S, Schwob O, Benny O.

Exp Eye Res. 2016 Jul;148:74-78. doi: 10.1016/j.exer.2016.05.024. Epub 2016 May 31.

PMID:
27260483
22.

Proofreading neutralizes potential error hotspots in genetic code translation by transfer RNAs.

Zhang J, Ieong KW, Mellenius H, Ehrenberg M.

RNA. 2016 Jun;22(6):896-904. doi: 10.1261/rna.055632.115. Epub 2016 Apr 18.

23.

Mechanism of fusidic acid inhibition of RRF- and EF-G-dependent splitting of the bacterial post-termination ribosome.

Borg A, Pavlov M, Ehrenberg M.

Nucleic Acids Res. 2016 Apr 20;44(7):3264-75. doi: 10.1093/nar/gkw178. Epub 2016 Mar 21.

24.

Parental education and text messaging reminders as effective community based tools to increase HPV vaccination rates among Mexican American children.

Aragones A, Bruno DM, Ehrenberg M, Tonda-Salcedo J, Gany FM.

Prev Med Rep. 2015 Jun 25;2:554-8. doi: 10.1016/j.pmedr.2015.06.015. eCollection 2015.

25.

Molecular mechanism of viomycin inhibition of peptide elongation in bacteria.

Holm M, Borg A, Ehrenberg M, Sanyal S.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):978-83. doi: 10.1073/pnas.1517541113. Epub 2016 Jan 11.

26.

N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics.

Choi J, Ieong KW, Demirci H, Chen J, Petrov A, Prabhakar A, O'Leary SE, Dominissini D, Rechavi G, Soltis SM, Ehrenberg M, Puglisi JD.

Nat Struct Mol Biol. 2016 Feb;23(2):110-5. doi: 10.1038/nsmb.3148. Epub 2016 Jan 11.

27.

Complete kinetic mechanism for recycling of the bacterial ribosome.

Borg A, Pavlov M, Ehrenberg M.

RNA. 2016 Jan;22(1):10-21. doi: 10.1261/rna.053157.115. Epub 2015 Nov 2.

28.

Free RNA polymerase in Escherichia coli.

Patrick M, Dennis PP, Ehrenberg M, Bremer H.

Biochimie. 2015 Dec;119:80-91. doi: 10.1016/j.biochi.2015.10.015. Epub 2015 Oct 19.

PMID:
26482806
29.

Accuracy of initial codon selection by aminoacyl-tRNAs on the mRNA-programmed bacterial ribosome.

Zhang J, Ieong KW, Johansson M, Ehrenberg M.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9602-7. doi: 10.1073/pnas.1506823112. Epub 2015 Jul 20.

30.

DNA template dependent accuracy variation of nucleotide selection in transcription.

Mellenius H, Ehrenberg M.

PLoS One. 2015 Mar 23;10(3):e0119588. doi: 10.1371/journal.pone.0119588. eCollection 2015.

31.

On the pH dependence of class-1 RF-dependent termination of mRNA translation.

Indrisiunaite G, Pavlov MY, Heurgué-Hamard V, Ehrenberg M.

J Mol Biol. 2015 May 8;427(9):1848-60. doi: 10.1016/j.jmb.2015.01.007. Epub 2015 Jan 23.

32.

Preserved outer retina in AIPL1 Leber's congenital amaurosis: implications for gene therapy.

Aboshiha J, Dubis AM, van der Spuy J, Nishiguchi KM, Cheeseman EW, Ayuso C, Ehrenberg M, Simonelli F, Bainbridge JW, Michaelides M.

Ophthalmology. 2015 Apr;122(4):862-4. doi: 10.1016/j.ophtha.2014.11.019. Epub 2015 Jan 14. No abstract available.

PMID:
25596619
33.

Fusidic acid targets elongation factor G in several stages of translocation on the bacterial ribosome.

Borg A, Holm M, Shiroyama I, Hauryliuk V, Pavlov M, Sanyal S, Ehrenberg M.

J Biol Chem. 2015 Feb 6;290(6):3440-54. doi: 10.1074/jbc.M114.611608. Epub 2014 Dec 1.

34.

Determinants of the rate of mRNA translocation in bacterial protein synthesis.

Borg A, Ehrenberg M.

J Mol Biol. 2015 May 8;427(9):1835-47. doi: 10.1016/j.jmb.2014.10.027. Epub 2014 Nov 14.

35.

Combining Sodium Hyaluronate and Polyvinylpyrrolidone Therapies for the Rabbit Cornea: A New Approach to Relief of the Human Dry Eye Syndrome.

Ehrenberg M, Zolotariov E, Loeb E, Poliansky V, Levy A.

Curr Eye Res. 2015 Sep;40(9):913-22. doi: 10.3109/02713683.2014.969810. Epub 2014 Oct 20.

PMID:
25329624
36.

Goal-determined metrics to assess outcomes of esotropia surgery.

Ehrenberg M, Nihalani BR, Melvin P, Cain CE, Hunter DG, Dagi LR.

J AAPOS. 2014 Jun;18(3):211-6. doi: 10.1016/j.jaapos.2013.12.016.

PMID:
24924270
37.

Peptide formation by N-methyl amino acids in translation is hastened by higher pH and tRNA(Pro).

Wang J, Kwiatkowski M, Pavlov MY, Ehrenberg M, Forster AC.

ACS Chem Biol. 2014 Jun 20;9(6):1303-11. doi: 10.1021/cb500036a. Epub 2014 Apr 9.

PMID:
24673854
38.

A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids.

Ieong KW, Pavlov MY, Kwiatkowski M, Ehrenberg M, Forster AC.

RNA. 2014 May;20(5):632-43. doi: 10.1261/rna.042234.113. Epub 2014 Mar 26.

39.

Thermodynamic modeling of variations in the rate of RNA chain elongation of E. coli rrn operons.

Fange D, Mellenius H, Dennis PP, Ehrenberg M.

Biophys J. 2014 Jan 7;106(1):55-64. doi: 10.1016/j.bpj.2013.11.4487.

40.

Optimal control of gene expression for fast proteome adaptation to environmental change.

Pavlov MY, Ehrenberg M.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20527-32. doi: 10.1073/pnas.1309356110. Epub 2013 Dec 2.

41.

CRB1: one gene, many phenotypes.

Ehrenberg M, Pierce EA, Cox GF, Fulton AB.

Semin Ophthalmol. 2013 Sep-Nov;28(5-6):397-405. doi: 10.3109/08820538.2013.825277. Review.

PMID:
24138049
42.

Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1.

Pallesen J, Hashem Y, Korkmaz G, Koripella RK, Huang C, Ehrenberg M, Sanyal S, Frank J.

Elife. 2013 Jun 4;2:e00411. doi: 10.7554/eLife.00411.

43.

The impact of aminoglycosides on the dynamics of translation elongation.

Tsai A, Uemura S, Johansson M, Puglisi EV, Marshall RA, Aitken CE, Korlach J, Ehrenberg M, Puglisi JD.

Cell Rep. 2013 Feb 21;3(2):497-508. doi: 10.1016/j.celrep.2013.01.027. Epub 2013 Feb 14.

44.

Medium-dependent control of the bacterial growth rate.

Ehrenberg M, Bremer H, Dennis PP.

Biochimie. 2013 Apr;95(4):643-58. doi: 10.1016/j.biochi.2012.11.012. Epub 2012 Dec 7. Review.

PMID:
23228516
45.

Inefficient delivery but fast peptide bond formation of unnatural L-aminoacyl-tRNAs in translation.

Ieong KW, Pavlov MY, Kwiatkowski M, Forster AC, Ehrenberg M.

J Am Chem Soc. 2012 Oct 31;134(43):17955-62. doi: 10.1021/ja3063524. Epub 2012 Oct 22.

PMID:
23057558
46.

Positive allosteric feedback regulation of the stringent response enzyme RelA by its product.

Shyp V, Tankov S, Ermakov A, Kudrin P, English BP, Ehrenberg M, Tenson T, Elf J, Hauryliuk V.

EMBO Rep. 2012 Sep;13(9):835-9. doi: 10.1038/embor.2012.106. Epub 2012 Jul 20.

47.

Genetic code translation displays a linear trade-off between efficiency and accuracy of tRNA selection.

Johansson M, Zhang J, Ehrenberg M.

Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):131-6. doi: 10.1073/pnas.1116480109. Epub 2011 Dec 21.

48.

Preoperative Visual Loss is the Main Cause of Irreversible Poor Vision in Children with a Brain Tumor.

Goldenberg-Cohen N, Ehrenberg M, Toledano H, Kornreich L, Snir M, Yassur I, Cohen IJ, Michowiz S.

Front Neurol. 2011 Sep 30;2:62. doi: 10.3389/fneur.2011.00062. eCollection 2011.

49.

Comment on "The mechanism for activation of GTP hydrolysis on the ribosome".

Liljas A, Ehrenberg M, Åqvist J.

Science. 2011 Jul 1;333(6038):37; author reply 37. doi: 10.1126/science.1202472.

50.

Identification of enzyme inhibitory mechanisms from steady-state kinetics.

Fange D, Lovmar M, Pavlov MY, Ehrenberg M.

Biochimie. 2011 Sep;93(9):1623-9. doi: 10.1016/j.biochi.2011.05.031. Epub 2011 Jun 12.

PMID:
21689716

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