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Items: 1 to 50 of 86

1.

Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model.

Occhetta P, Mainardi A, Votta E, Vallmajo-Martin Q, Ehrbar M, Martin I, Barbero A, Rasponi M.

Nat Biomed Eng. 2019 Jun 3. doi: 10.1038/s41551-019-0406-3. [Epub ahead of print]

PMID:
31160722
2.

Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments.

Blache U, Horton ER, Xia T, Schoof EM, Blicher LH, Schönenberger A, Snedeker JG, Martin I, Erler JT, Ehrbar M.

Life Sci Alliance. 2019 Jun 3;2(3). pii: e201900304. doi: 10.26508/lsa.201900304. Print 2019 Jun.

3.

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.

Vannini N, Campos V, Girotra M, Trachsel V, Rojas-Sutterlin S, Tratwal J, Ragusa S, Stefanidis E, Ryu D, Rainer PY, Nikitin G, Giger S, Li TY, Semilietof A, Oggier A, Yersin Y, Tauzin L, Pirinen E, Cheng WC, Ratajczak J, Canto C, Ehrbar M, Sizzano F, Petrova TV, Vanhecke D, Zhang L, Romero P, Nahimana A, Cherix S, Duchosal MA, Ho PC, Deplancke B, Coukos G, Auwerx J, Lutolf MP, Naveiras O.

Cell Stem Cell. 2019 Mar 7;24(3):405-418.e7. doi: 10.1016/j.stem.2019.02.012.

PMID:
30849366
4.

Quantitative in vitro comparison of the thrombogenicity of commercial dental implants.

Milleret V, Lienemann PS, Bauer S, Ehrbar M.

Clin Implant Dent Relat Res. 2019 Mar;21 Suppl 1:8-14. doi: 10.1111/cid.12737. Epub 2019 Feb 28.

PMID:
30816636
5.

Rational design and in vitro characterization of novel dental implant and abutment surfaces for balancing clinical and biological needs.

Milleret V, Lienemann PS, Gasser A, Bauer S, Ehrbar M, Wennerberg A.

Clin Implant Dent Relat Res. 2019 Mar;21 Suppl 1:15-24. doi: 10.1111/cid.12736. Epub 2019 Feb 27.

PMID:
30809940
6.

Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels.

Devaud YR, Avilla-Royo E, Trachsel C, Grossmann J, Martin I, Lutolf MP, Ehrbar M.

Adv Healthc Mater. 2018 Nov;7(21):e1800534. doi: 10.1002/adhm.201800534. Epub 2018 Sep 27.

PMID:
30260582
7.

Inspired by Nature: Hydrogels as Versatile Tools for Vascular Engineering.

Blache U, Ehrbar M.

Adv Wound Care (New Rochelle). 2018 Jul 1;7(7):232-246. doi: 10.1089/wound.2017.0760. Review.

8.

Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate.

Blache U, Vallmajo-Martin Q, Horton ER, Guerrero J, Djonov V, Scherberich A, Erler JT, Martin I, Snedeker JG, Milleret V, Ehrbar M.

EMBO Rep. 2018 Aug;19(8). pii: e45964. doi: 10.15252/embr.201845964. Epub 2018 Jul 2.

PMID:
29967223
9.

Minimally Invasive Surgical Device for Precise Application of Bioadhesives to Prevent iPPROM.

Devaud YR, Züger S, Zimmermann R, Ehrbar M, Ochsenbein-Kölble N.

Fetal Diagn Ther. 2019;45(2):102-110. doi: 10.1159/000487393. Epub 2018 Jun 19.

PMID:
29920508
10.

Spatially confined induction of endochondral ossification by functionalized hydrogels for ectopic engineering of osteochondral tissues.

Stüdle C, Vallmajó-Martín Q, Haumer A, Guerrero J, Centola M, Mehrkens A, Schaefer DJ, Ehrbar M, Barbero A, Martin I.

Biomaterials. 2018 Jul;171:219-229. doi: 10.1016/j.biomaterials.2018.04.025. Epub 2018 Apr 21.

PMID:
29705655
11.

Automatic registration of 2D histological sections to 3D microCT volumes: Trabecular bone.

Lundin EL, Stauber M, Papageorgiou P, Ehrbar M, Ghayor C, Weber FE, Tanner C, Goksel O.

Bone. 2017 Dec;105:173-183. doi: 10.1016/j.bone.2017.08.021. Epub 2017 Sep 1.

PMID:
28867374
12.

Soft Hydrogels Featuring In-Depth Surface Density Gradients for the Simple Establishment of 3D Tissue Models for Screening Applications.

Zhang N, Milleret V, Thompson-Steckel G, Huang NP, Vörös J, Simona BR, Ehrbar M.

SLAS Discov. 2017 Jun;22(5):635-644. doi: 10.1177/2472555217693191. Epub 2017 Mar 9.

PMID:
28277889
13.

Single cell-laden protease-sensitive microniches for long-term culture in 3D.

Lienemann PS, Rossow T, Mao AS, Vallmajo-Martin Q, Ehrbar M, Mooney DJ.

Lab Chip. 2017 Feb 14;17(4):727-737. doi: 10.1039/c6lc01444e.

14.

Ultra-hydrophilic stent platforms promote early vascular healing and minimise late tissue response: a potential alternative to second-generation drug-eluting stents.

Kolandaivelu K, Bailey L, Buzzi S, Zucker A, Milleret V, Ziogas A, Ehrbar M, Khattab AA, Stanley JRL, Wong GK, Zani B, Markham PM, Tzafriri AR, Bhatt DL, Edelman ER.

EuroIntervention. 2017 Apr 20;12(17):2148-2156. doi: 10.4244/EIJ-D-15-00497.

15.

A Novel Bioreactor System for the Assessment of Endothelialization on Deformable Surfaces.

Bachmann BJ, Bernardi L, Loosli C, Marschewski J, Perrini M, Ehrbar M, Ermanni P, Poulikakos D, Ferrari A, Mazza E.

Sci Rep. 2016 Dec 12;6:38861. doi: 10.1038/srep38861.

16.

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.

Reuten R, Patel TR, McDougall M, Rama N, Nikodemus D, Gibert B, Delcros JG, Prein C, Meier M, Metzger S, Zhou Z, Kaltenberg J, McKee KK, Bald T, Tüting T, Zigrino P, Djonov V, Bloch W, Clausen-Schaumann H, Poschl E, Yurchenco PD, Ehrbar M, Mehlen P, Stetefeld J, Koch M.

Nat Commun. 2016 Nov 30;7:13515. doi: 10.1038/ncomms13515.

17.

One-Step Microfluidic Fabrication of Polyelectrolyte Microcapsules in Aqueous Conditions for Protein Release.

Zhang L, Cai LH, Lienemann PS, Rossow T, Polenz I, Vallmajo-Martin Q, Ehrbar M, Na H, Mooney DJ, Weitz DA.

Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13470-13474. doi: 10.1002/anie.201606960. Epub 2016 Sep 26.

PMID:
27717141
18.

Cell-Mediated Proteolytic Release of Growth Factors from Poly(Ethylene Glycol) Matrices.

Metzger S, Blache U, Lienemann PS, Karlsson M, Weber FE, Weber W, Ehrbar M.

Macromol Biosci. 2016 Nov;16(11):1703-1713. doi: 10.1002/mabi.201600223. Epub 2016 Aug 22.

PMID:
27548907
19.

Enzyme responsive GAG-based natural-synthetic hybrid hydrogel for tunable growth factor delivery and stem cell differentiation.

Anjum F, Lienemann PS, Metzger S, Biernaskie J, Kallos MS, Ehrbar M.

Biomaterials. 2016 May;87:104-117. doi: 10.1016/j.biomaterials.2016.01.050. Epub 2016 Feb 8.

PMID:
26914701
20.

Dual Role of Mesenchymal Stem Cells Allows for Microvascularized Bone Tissue-Like Environments in PEG Hydrogels.

Blache U, Metzger S, Vallmajo-Martin Q, Martin I, Djonov V, Ehrbar M.

Adv Healthc Mater. 2016 Feb 18;5(4):489-98. doi: 10.1002/adhm.201500795. Epub 2015 Dec 22.

PMID:
26693678
21.

Erratum: Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering.

Lienemann PS, Metzger S, Kiveliö AS, Blanc A, Papageorgiou P, Astolfo A, Pinzer BR, Cinelli P, Weber FE, Schibli R, Béhé M, Ehrbar M.

Sci Rep. 2015 Nov 12;5:12391. doi: 10.1038/srep12391. No abstract available.

22.

A comparative investigation of mussel-mimetic sealants for fetal membrane repair.

Perrini M, Barrett D, Ochsenbein-Koelble N, Zimmermann R, Messersmith P, Ehrbar M.

J Mech Behav Biomed Mater. 2016 May;58:57-64. doi: 10.1016/j.jmbbm.2015.07.009. Epub 2015 Jul 26.

PMID:
26255212
23.

Density gradients at hydrogel interfaces for enhanced cell penetration.

Simona BR, Hirt L, Demkó L, Zambelli T, Vörös J, Ehrbar M, Milleret V.

Biomater Sci. 2015 Apr;3(4):586-91. doi: 10.1039/c4bm00416g. Epub 2015 Jan 14.

PMID:
26222418
24.

Protein adsorption steers blood contact activation on engineered cobalt chromium alloy oxide layers.

Milleret V, Buzzi S, Gehrig P, Ziogas A, Grossmann J, Schilcher K, Zinkernagel AS, Zucker A, Ehrbar M.

Acta Biomater. 2015 Sep;24:343-51. doi: 10.1016/j.actbio.2015.06.020. Epub 2015 Jun 20.

PMID:
26102336
25.

Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering.

Lienemann PS, Metzger S, Kiveliö AS, Blanc A, Papageorgiou P, Astolfo A, Pinzer BR, Cinelli P, Weber FE, Schibli R, Béhé M, Ehrbar M.

Sci Rep. 2015 May 19;5:10238. doi: 10.1038/srep10238. Erratum in: Sci Rep. 2015;5:12391.

26.

Deformation mechanisms of human amnion: Quantitative studies based on second harmonic generation microscopy.

Mauri A, Ehret AE, Perrini M, Maake C, Ochsenbein-Kölble N, Ehrbar M, Oyen ML, Mazza E.

J Biomech. 2015 Jun 25;48(9):1606-13. doi: 10.1016/j.jbiomech.2015.01.045. Epub 2015 Feb 7.

PMID:
25805698
27.

Mechanical and microstructural investigation of the cyclic behavior of human amnion.

Perrini M, Mauri A, Ehret AE, Ochsenbein-Kölble N, Zimmermann R, Ehrbar M, Mazza E.

J Biomech Eng. 2015 Jun;137(6):061010. doi: 10.1115/1.4030054. Epub 2015 Apr 15.

PMID:
25780908
28.

Precision assembly of complex cellular microenvironments using holographic optical tweezers.

Kirkham GR, Britchford E, Upton T, Ware J, Gibson GM, Devaud Y, Ehrbar M, Padgett M, Allen S, Buttery LD, Shakesheff K.

Sci Rep. 2015 Feb 26;5:8577. doi: 10.1038/srep08577.

29.

Engineered cell instructive matrices for fetal membrane healing.

Kivelio A, Ochsenbein-Koelble N, Zimmermann R, Ehrbar M.

Acta Biomater. 2015 Mar;15:1-10. doi: 10.1016/j.actbio.2014.12.011. Epub 2014 Dec 20.

PMID:
25536031
30.

Locally controlling mesenchymal stem cell morphogenesis by 3D PDGF-BB gradients towards the establishment of an in vitro perivascular niche.

Lienemann PS, Devaud YR, Reuten R, Simona BR, Karlsson M, Weber W, Koch M, Lutolf MP, Milleret V, Ehrbar M.

Integr Biol (Camb). 2015 Jan;7(1):101-11. doi: 10.1039/c4ib00152d.

PMID:
25385042
31.

Modular poly(ethylene glycol) matrices for the controlled 3D-localized osteogenic differentiation of mesenchymal stem cells.

Metzger S, Lienemann PS, Ghayor C, Weber W, Martin I, Weber FE, Ehrbar M.

Adv Healthc Mater. 2015 Mar 11;4(4):550-8. doi: 10.1002/adhm.201400547. Epub 2014 Oct 31.

PMID:
25358649
32.

Inhibition of angiogenesis by antioxidant micelles.

Moriyama M, Metzger S, van der Vlies AJ, Uyama H, Ehrbar M, Hasegawa U.

Adv Healthc Mater. 2015 Mar 11;4(4):569-75. doi: 10.1002/adhm.201400249. Epub 2014 Sep 11.

PMID:
25213436
33.

Effect of oxide layer modification of CoCr stent alloys on blood activation and endothelial behavior.

Milleret V, Ziogas A, Buzzi S, Heuberger R, Zucker A, Ehrbar M.

J Biomed Mater Res B Appl Biomater. 2015 Apr;103(3):629-40. doi: 10.1002/jbm.b.33232. Epub 2014 Jun 26.

PMID:
24964763
34.

Effect of different rhBMP-2 and TG-VEGF ratios on the formation of heterotopic bone and neovessels.

Cai WX, Zheng LW, Li CL, Ma L, Ehrbar M, Weber FE, Zwahlen RA.

Biomed Res Int. 2014;2014:571510. doi: 10.1155/2014/571510. Epub 2014 Mar 24.

35.

Long-lasting fibrin matrices ensure stable and functional angiogenesis by highly tunable, sustained delivery of recombinant VEGF164.

Sacchi V, Mittermayr R, Hartinger J, Martino MM, Lorentz KM, Wolbank S, Hofmann A, Largo RA, Marschall JS, Groppa E, Gianni-Barrera R, Ehrbar M, Hubbell JA, Redl H, Banfi A.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):6952-7. doi: 10.1073/pnas.1404605111. Epub 2014 Apr 28.

36.

Delivery of BMP-2 by two clinically available apatite materials: in vitro and in vivo comparison.

Hänseler P, Ehrbar M, Kruse A, Fischer E, Schibli R, Ghayor C, Weber FE.

J Biomed Mater Res A. 2015 Feb;103(2):628-38. doi: 10.1002/jbm.a.35211. Epub 2014 May 9.

PMID:
24771467
37.

Electrochemical control of the enzymatic polymerization of PEG hydrogels: formation of spatially controlled biological microenvironments.

Milleret V, Simona BR, Lienemann PS, Vörös J, Ehrbar M.

Adv Healthc Mater. 2014 Apr;3(4):508-14. doi: 10.1002/adhm.201300479. Epub 2013 Oct 30.

PMID:
24574303
38.

In situ cell manipulation through enzymatic hydrogel photopatterning.

Mosiewicz KA, Kolb L, van der Vlies AJ, Martino MM, Lienemann PS, Hubbell JA, Ehrbar M, Lutolf MP.

Nat Mater. 2013 Nov;12(11):1072-8. doi: 10.1038/nmat3766. Epub 2013 Oct 13.

PMID:
24121990
39.

Mussel mimetic tissue adhesive for fetal membrane repair: initial in vivo investigation in rabbits.

Kivelio A, Dekoninck P, Perrini M, Brubaker CE, Messersmith PB, Mazza E, Deprest J, Zimmermann R, Ehrbar M, Ochsenbein-Koelble N.

Eur J Obstet Gynecol Reprod Biol. 2013 Dec;171(2):240-5. doi: 10.1016/j.ejogrb.2013.09.003. Epub 2013 Sep 11.

PMID:
24075447
40.

Second harmonic generation microscopy of fetal membranes under deformation: normal and altered morphology.

Mauri A, Perrini M, Mateos JM, Maake C, Ochsenbein-Koelble N, Zimmermann R, Ehrbar M, Mazza E.

Placenta. 2013 Nov;34(11):1020-6. doi: 10.1016/j.placenta.2013.09.002. Epub 2013 Sep 13.

41.

Pharmacologically controlled protein switch for ON-OFF regulation of growth factor activity.

Karlsson M, Rebmann B, Lienemann PS, Sprossmann N, Ehrbar M, Radziwill G, Weber W.

Sci Rep. 2013;3:2716. doi: 10.1038/srep02716.

42.

Pharmacologically triggered hydrogel for scheduling hepatitis B vaccine administration.

Gübeli RJ, Schöneweis K, Huzly D, Ehrbar M, Charpin-El Hamri G, El-Baba MD, Urban S, Weber W.

Sci Rep. 2013;3:2610. doi: 10.1038/srep02610.

43.

Heterotopic bone formation around vessels: pilot study of a new animal model.

Cai WX, Zheng LW, Weber FE, Li CL, Ma L, Ehrbar M, Zwahlen RA.

Biores Open Access. 2013 Aug;2(4):266-72. doi: 10.1089/biores.2013.0025.

44.

A generic strategy for pharmacological caging of growth factors for tissue engineering.

Karlsson M, Lienemann PS, Sprossmann N, Heilmann K, Brummer T, Lutolf MP, Ehrbar M, Weber W.

Chem Commun (Camb). 2013 Jul 7;49(53):5927-9. doi: 10.1039/c3cc41616j.

45.

Pharmacologically tunable polyethylene-glycol-based cell growth substrate.

Gübeli RJ, Laird D, Ehrbar M, Ritter BS, Steinberg T, Tomakidi P, Weber W.

Acta Biomater. 2013 Sep;9(9):8272-8. doi: 10.1016/j.actbio.2013.05.008. Epub 2013 May 16.

PMID:
23684763
46.

Proteolytic processing regulates placental growth factor activities.

Hoffmann DC, Willenborg S, Koch M, Zwolanek D, Müller S, Becker AK, Metzger S, Ehrbar M, Kurschat P, Hellmich M, Hubbell JA, Eming SA.

J Biol Chem. 2013 Jun 21;288(25):17976-89. doi: 10.1074/jbc.M113.451831. Epub 2013 May 3.

47.

A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells.

Müller K, Engesser R, Metzger S, Schulz S, Kämpf MM, Busacker M, Steinberg T, Tomakidi P, Ehrbar M, Nagy F, Timmer J, Zubriggen MD, Weber W.

Nucleic Acids Res. 2013 Apr;41(7):e77. doi: 10.1093/nar/gkt002. Epub 2013 Jan 25.

48.

Characterization of epicardial-derived cardiac interstitial cells: differentiation and mobilization of heart fibroblast progenitors.

Ruiz-Villalba A, Ziogas A, Ehrbar M, Pérez-Pomares JM.

PLoS One. 2013;8(1):e53694. doi: 10.1371/journal.pone.0053694. Epub 2013 Jan 18.

49.

A versatile approach to engineering biomolecule-presenting cellular microenvironments.

Lienemann PS, Karlsson M, Sala A, Wischhusen HM, Weber FE, Zimmermann R, Weber W, Lutolf MP, Ehrbar M.

Adv Healthc Mater. 2013 Feb;2(2):292-6. doi: 10.1002/adhm.201200280. Epub 2012 Nov 7. No abstract available.

PMID:
23184806
50.

Contractions, a risk for premature rupture of fetal membranes: a new protocol with cyclic biaxial tension.

Perrini M, Bürzle W, Haller C, Ochsenbein-Kölble N, Deprest J, Zimmermann R, Mazza E, Ehrbar M.

Med Eng Phys. 2013 Jun;35(6):846-51. doi: 10.1016/j.medengphy.2012.08.014. Epub 2012 Sep 19.

PMID:
22998894

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