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Items: 15


A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6.

Priestley RS, Cheung J, Murphy EJ, Ehebauer MT, Davis JB, Di Daniel E.

J Pharmacol Toxicol Methods. 2019 Jan - Feb;95:47-55. doi: 10.1016/j.vascn.2018.11.003. Epub 2018 Nov 23.


Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.

Quevedo CE, Cruz-Migoni A, Bery N, Miller A, Tanaka T, Petch D, Bataille CJR, Lee LYW, Fallon PS, Tulmin H, Ehebauer MT, Fernandez-Fuentes N, Russell AJ, Carr SB, Phillips SEV, Rabbitts TH.

Nat Commun. 2018 Aug 9;9(1):3169. doi: 10.1038/s41467-018-05707-2.


Discovery of a PCAF Bromodomain Chemical Probe.

Moustakim M, Clark PG, Trulli L, Fuentes de Arriba AL, Ehebauer MT, Chaikuad A, Murphy EJ, Mendez-Johnson J, Daniels D, Hou CD, Lin YH, Walker JR, Hui R, Yang H, Dorrell L, Rogers CM, Monteiro OP, Fedorov O, Huber KV, Knapp S, Heer J, Dixon DJ, Brennan PE.

Angew Chem Int Ed Engl. 2017 Jan 16;56(3):827-831. doi: 10.1002/anie.201610816. Epub 2016 Dec 14.


ATP half-sites in RadA and RAD51 recombinases bind nucleotides.

Marsh ME, Scott DE, Ehebauer MT, Abell C, Blundell TL, Hyvönen M.

FEBS Open Bio. 2016 Apr 6;6(5):372-85. doi: 10.1002/2211-5463.12052. eCollection 2016 May.


Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolism.

Ehebauer MT, Zimmermann M, Jakobi AJ, Noens EE, Laubitz D, Cichocki B, Marrakchi H, Lanéelle MA, Daffé M, Sachse C, Dziembowski A, Sauer U, Wilmanns M.

PLoS Pathog. 2015 Feb 19;11(2):e1004623. doi: 10.1371/journal.ppat.1004623. eCollection 2015 Feb.


Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis.

Ma Q, Akhter Y, Wilmanns M, Ehebauer MT.

Protein Sci. 2014 Jul;23(7):932-9. doi: 10.1002/pro.2475. Epub 2014 Apr 22.


Using a fragment-based approach to target protein-protein interactions.

Scott DE, Ehebauer MT, Pukala T, Marsh M, Blundell TL, Venkitaraman AR, Abell C, Hyvönen M.

Chembiochem. 2013 Feb 11;14(3):332-42. doi: 10.1002/cbic.201200521. Epub 2013 Jan 23.


The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: perhaps more?

Akhter Y, Ehebauer MT, Mukhopadhyay S, Hasnain SE.

Biochimie. 2012 Jan;94(1):110-6. doi: 10.1016/j.biochi.2011.09.026. Epub 2011 Oct 12. Review.


The progress made in determining the Mycobacterium tuberculosis structural proteome.

Ehebauer MT, Wilmanns M.

Proteomics. 2011 Aug;11(15):3128-33. doi: 10.1002/pmic.201000787. Epub 2011 Jun 14. Review.


Improved mycobacterial protein production using a Mycobacterium smegmatis groEL1ΔC expression strain.

Noens EE, Williams C, Anandhakrishnan M, Poulsen C, Ehebauer MT, Wilmanns M.

BMC Biotechnol. 2011 Mar 25;11:27. doi: 10.1186/1472-6750-11-27.


The structural and functional determinants of the Axin and Dishevelled DIX domains.

Ehebauer MT, Arias AM.

BMC Struct Biol. 2009 Nov 12;9:70. doi: 10.1186/1472-6807-9-70.


Notch signaling pathway.

Ehebauer M, Hayward P, Martinez-Arias A.

Sci STKE. 2006 Dec 5;2006(364):cm7. Review.


Notch, a universal arbiter of cell fate decisions.

Ehebauer M, Hayward P, Arias AM.

Science. 2006 Dec 1;314(5804):1414-5.


High-resolution crystal structure of the human Notch 1 ankyrin domain.

Ehebauer MT, Chirgadze DY, Hayward P, Martinez Arias A, Blundell TL.

Biochem J. 2005 Nov 15;392(Pt 1):13-20.


Identification of extrinsic blood coagulation pathway inhibitors from the tick Ornithodoros savignyi (Acari: Argasidae).

Ehebauer MT, Mans BJ, Gaspar AR, Neitz AW.

Exp Parasitol. 2002 Jun-Jul;101(2-3):138-48.


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