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Items: 1 to 50 of 96

1.

Pancreatic Beta Cell Differentiation From Human Pluripotent Stem Cells.

Sui L, Leibel RL, Egli D.

Curr Protoc Hum Genet. 2018 Sep 7:e68. doi: 10.1002/cphg.68. [Epub ahead of print]

PMID:
30192441
2.

Inter-homologue repair in fertilized human eggs?

Egli D, Zuccaro MV, Kosicki M, Church GM, Bradley A, Jasin M.

Nature. 2018 Aug;560(7717):E5-E7. doi: 10.1038/s41586-018-0379-5. Epub 2018 Aug 8. No abstract available.

PMID:
30089924
3.

Identification and Analysis of Islet Antigen-Specific CD8+ T Cells with T Cell Libraries.

Ogura H, Preston-Hurlburt P, Perdigoto AL, Amodio M, Krishnaswamy S, Clark P, Yu H, Egli D, Fouts A, Steck AK, Herold KC.

J Immunol. 2018 Sep 15;201(6):1662-1670. doi: 10.4049/jimmunol.1800267. Epub 2018 Aug 6.

PMID:
30082321
4.

Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes.

Zakarin Safier L, Gumer A, Kline M, Egli D, Sauer MV.

J Assist Reprod Genet. 2018 Jun 5. doi: 10.1007/s10815-018-1171-z. [Epub ahead of print]

PMID:
29872942
5.

ILDR2 has a negligible role in hepatic steatosis.

Millings EJ, De Rosa MC, Fleet S, Watanabe K, Rausch R, Egli D, Li G, Leduc CA, Zhang Y, Fischer SG, Leibel RL.

PLoS One. 2018 May 30;13(5):e0197548. doi: 10.1371/journal.pone.0197548. eCollection 2018.

6.

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.

Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D'Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A.

Transplantation. 2018 Aug;102(8):1223-1229. doi: 10.1097/TP.0000000000002217.

PMID:
29781950
7.

Derivation and characterization of the NIH registry human stem cell line NYSCF101 under defined feeder-free conditions.

Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S.

Stem Cell Res. 2018 May;29:197-201. doi: 10.1016/j.scr.2018.04.017. Epub 2018 Apr 30.

8.

Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions.

Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S.

Stem Cell Res. 2018 May;29:99-102. doi: 10.1016/j.scr.2018.03.017. Epub 2018 Mar 31.

9.

Derivation and characterization of the NYSCFe003-A human embryonic stem cell line.

Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S.

Stem Cell Res. 2017 Dec;25:217-220. doi: 10.1016/j.scr.2017.10.017. Epub 2017 Nov 21.

10.

β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.

Sui L, Danzl N, Campbell SR, Viola R, Williams D, Xing Y, Wang Y, Phillips N, Poffenberger G, Johannesson B, Oberholzer J, Powers AC, Leibel RL, Chen X, Sykes M, Egli D.

Diabetes. 2018 Jan;67(1):26-35. doi: 10.2337/db17-0120. Epub 2017 Sep 20.

11.

Tying genetic stability to cell identity.

Georgieva D, Egli D.

Cell Cycle. 2017 Jun 18;16(12):1139-1140. doi: 10.1080/15384101.2017.1324126. No abstract available.

12.

Genomic instability during reprogramming by nuclear transfer is DNA replication dependent.

Chia G, Agudo J, Treff N, Sauer MV, Billing D, Brown BD, Baer R, Egli D.

Nat Cell Biol. 2017 Apr;19(4):282-291. doi: 10.1038/ncb3485. Epub 2017 Mar 6.

13.

Growth of Infants Fed Formula with Evolving  Nutrition Composition: A Single-Arm Non-Inferiority Study.

Spalinger J, Nydegger A, Belli D, Furlano RI, Yan J, Tanguy J, Pecquet S, Destaillats F, Egli D, Steenhout P.

Nutrients. 2017 Mar 1;9(3). pii: E219. doi: 10.3390/nu9030219.

14.

Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes.

Yamada M, Egli D.

Stem Cell Reports. 2017 Mar 14;8(3):576-588. doi: 10.1016/j.stemcr.2017.01.020. Epub 2017 Feb 24.

15.

PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons.

Wang L, Sui L, Panigrahi SK, Meece K, Xin Y, Kim J, Gromada J, Doege CA, Wardlaw SL, Egli D, Leibel RL.

Stem Cell Reports. 2017 Feb 14;8(2):264-277. doi: 10.1016/j.stemcr.2016.12.021. Epub 2017 Jan 26.

16.

Effects of Infant Formula With Human Milk Oligosaccharides on Growth and Morbidity: A Randomized Multicenter Trial.

Puccio G, Alliet P, Cajozzo C, Janssens E, Corsello G, Sprenger N, Wernimont S, Egli D, Gosoniu L, Steenhout P.

J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):624-631. doi: 10.1097/MPG.0000000000001520.

17.

iPSC-derived β cells model diabetes due to glucokinase deficiency.

Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, LeDuc C, Chung WK, Goland R, Leibel RL, Egli D.

J Clin Invest. 2017 Mar 1;127(3):1115. doi: 10.1172/JCI92775. Epub 2017 Jan 17. No abstract available.

18.

Inconsistency in 'three-parent' IVF study.

Egli D.

Reprod Biomed Online. 2017 Mar;34(3):280. doi: 10.1016/j.rbmo.2016.12.010. Epub 2016 Dec 16. No abstract available.

PMID:
28038847
19.

Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome.

Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, Dubern B, Poitou C, Clement K, Butler MG, Rosenbaum M, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL.

J Clin Invest. 2017 Jan 3;127(1):293-305. doi: 10.1172/JCI88648. Epub 2016 Dec 12.

20.

Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS.

Burnett LC, LeDuc CA, Sulsona CR, Paull D, Eddiry S, Levy B, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL.

Stem Cell Res. 2016 Nov;17(3):526-530. doi: 10.1016/j.scr.2016.08.008. Epub 2016 Aug 16.

21.

Identification and propagation of haploid human pluripotent stem cells.

Sagi I, Egli D, Benvenisty N.

Nat Protoc. 2016 Nov;11(11):2274-2286. doi: 10.1038/nprot.2016.145. Epub 2016 Oct 20.

PMID:
27763625
22.

Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq.

Weissbein U, Schachter M, Egli D, Benvenisty N.

Nat Commun. 2016 Jul 7;7:12144. doi: 10.1038/ncomms12144.

23.

Efficient Generation of Hypothalamic Neurons from Human Pluripotent Stem Cells.

Wang L, Egli D, Leibel RL.

Curr Protoc Hum Genet. 2016 Jul 1;90:21.5.1-21.5.14. doi: 10.1002/cphg.3.

24.

Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes.

Yamada M, Emmanuele V, Sanchez-Quintero MJ, Sun B, Lallos G, Paull D, Zimmer M, Pagett S, Prosser RW, Sauer MV, Hirano M, Egli D.

Cell Stem Cell. 2016 Jun 2;18(6):749-54. doi: 10.1016/j.stem.2016.04.001. Epub 2016 May 19.

25.

Hypomorphism of Fto and Rpgrip1l causes obesity in mice.

Stratigopoulos G, Burnett LC, Rausch R, Gill R, Penn DB, Skowronski AA, LeDuc CA, Lanzano AJ, Zhang P, Storm DR, Egli D, Leibel RL.

J Clin Invest. 2016 May 2;126(5):1897-910. doi: 10.1172/JCI85526. Epub 2016 Apr 11.

26.

Derivation and differentiation of haploid human embryonic stem cells.

Sagi I, Chia G, Golan-Lev T, Peretz M, Weissbein U, Sui L, Sauer MV, Yanuka O, Egli D, Benvenisty N.

Nature. 2016 Apr 7;532(7597):107-11. doi: 10.1038/nature17408. Epub 2016 Mar 16.

PMID:
26982723
27.

Attitudes toward prevention of mtDNA-related diseases through oocyte mitochondrial replacement therapy.

Engelstad K, Sklerov M, Kriger J, Sanford A, Grier J, Ash D, Egli D, DiMauro S, Thompson JL, Sauer MV, Hirano M.

Hum Reprod. 2016 May;31(5):1058-65. doi: 10.1093/humrep/dew033. Epub 2016 Mar 2.

28.

Human embryos commonly form abnormal nuclei during development: a mechanism of DNA damage, embryonic aneuploidy, and developmental arrest.

Kort DH, Chia G, Treff NR, Tanaka AJ, Xing T, Vensand LB, Micucci S, Prosser R, Lobo RA, Sauer MV, Egli D.

Hum Reprod. 2016 Feb;31(2):312-23. doi: 10.1093/humrep/dev281. Epub 2015 Nov 29.

PMID:
26621855
29.

GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions.

Agudo J, Ruzo A, Park ES, Sweeney R, Kana V, Wu M, Zhao Y, Egli D, Merad M, Brown BD.

Nat Biotechnol. 2015 Dec;33(12):1287-1292. doi: 10.1038/nbt.3386. Epub 2015 Nov 2.

30.

From cloned frogs to patient matched stem cells: induced pluripotency or somatic cell nuclear transfer?

Yamada M, Byrne J, Egli D.

Curr Opin Genet Dev. 2015 Oct;34:29-34. doi: 10.1016/j.gde.2015.06.007. Epub 2015 Aug 15. Review.

PMID:
26282611
31.

Stem Cell-Derived Beta Cells for Treatment of Type 1 Diabetes?

Goland R, Egli D.

EBioMedicine. 2014 Oct 29;1(2-3):93-4. doi: 10.1016/j.ebiom.2014.10.018. eCollection 2014 Dec. No abstract available.

32.

Toward beta cell replacement for diabetes.

Johannesson B, Sui L, Freytes DO, Creusot RJ, Egli D.

EMBO J. 2015 Apr 1;34(7):841-55. doi: 10.15252/embj.201490685. Epub 2015 Mar 1. Review.

33.

Differentiation of hypothalamic-like neurons from human pluripotent stem cells.

Wang L, Meece K, Williams DJ, Lo KA, Zimmer M, Heinrich G, Martin Carli J, Leduc CA, Sun L, Zeltser LM, Freeby M, Goland R, Tsang SH, Wardlaw SL, Egli D, Leibel RL.

J Clin Invest. 2015 Feb;125(2):796-808. doi: 10.1172/JCI79220. Epub 2015 Jan 2.

34.

Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors.

Johannesson B, Sagi I, Gore A, Paull D, Yamada M, Golan-Lev T, Li Z, LeDuc C, Shen Y, Stern S, Xu N, Ma H, Kang E, Mitalipov S, Sauer MV, Zhang K, Benvenisty N, Egli D.

Cell Stem Cell. 2014 Nov 6;15(5):634-42. doi: 10.1016/j.stem.2014.10.002. Epub 2014 Nov 6.

35.

FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures.

Bouchi R, Foo KS, Hua H, Tsuchiya K, Ohmura Y, Sandoval PR, Ratner LE, Egli D, Leibel RL, Accili D.

Nat Commun. 2014 Jun 30;5:4242. doi: 10.1038/ncomms5242.

36.

Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects.

Li Y, Wu WH, Hsu CW, Nguyen HV, Tsai YT, Chan L, Nagasaki T, Maumenee IH, Yannuzzi LA, Hoang QV, Hua H, Egli D, Tsang SH.

Mol Ther. 2014 Sep;22(9):1688-97. doi: 10.1038/mt.2014.100. Epub 2014 Jun 4.

37.

A Randomized Double Blind Controlled Safety Trial Evaluating d-Lactic Acid Production in Healthy Infants Fed a Lactobacillus reuteri-containing Formula.

Papagaroufalis K, Fotiou A, Egli D, Tran LA, Steenhout P.

Nutr Metab Insights. 2014 Apr 22;7:19-27. doi: 10.4137/NMI.S14113. eCollection 2014.

38.

Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice.

Stratigopoulos G, Martin Carli JF, O'Day DR, Wang L, Leduc CA, Lanzano P, Chung WK, Rosenbaum M, Egli D, Doherty DA, Leibel RL.

Cell Metab. 2014 May 6;19(5):767-79. doi: 10.1016/j.cmet.2014.04.009.

39.

Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells.

Yamada M, Johannesson B, Sagi I, Burnett LC, Kort DH, Prosser RW, Paull D, Nestor MW, Freeby M, Greenberg E, Goland RS, Leibel RL, Solomon SL, Benvenisty N, Sauer MV, Egli D.

Nature. 2014 Jun 26;510(7506):533-6. doi: 10.1038/nature13287. Epub 2014 Apr 28.

PMID:
24776804
40.

Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia.

Heymsfield SB, Avena NM, Baier L, Brantley P, Bray GA, Burnett LC, Butler MG, Driscoll DJ, Egli D, Elmquist J, Forster JL, Goldstone AP, Gourash LM, Greenway FL, Han JC, Kane JG, Leibel RL, Loos RJ, Scheimann AO, Roth CL, Seeley RJ, Sheffield V, Tauber M, Vaisse C, Wang L, Waterland RA, Wevrick R, Yanovski JA, Zinn AR.

Obesity (Silver Spring). 2014 Feb;22 Suppl 1:S1-S17. doi: 10.1002/oby.20646.

41.

Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines.

Yang J, Li Y, Chan L, Tsai YT, Wu WH, Nguyen HV, Hsu CW, Li X, Brown LM, Egli D, Sparrow JR, Tsang SH.

Hum Mol Genet. 2014 Jul 1;23(13):3445-55. doi: 10.1093/hmg/ddu053. Epub 2014 Feb 4.

42.

Harnessing the stem cell potential: the path to prevent mitochondrial disease.

Tanaka AJ, Sauer MV, Egli D, Kort DH.

Nat Med. 2013 Dec;19(12):1578-9. doi: 10.1038/nm.3422. No abstract available.

PMID:
24309656
43.

Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis.

Dowdle JA, Mehta M, Kass EM, Vuong BQ, Inagaki A, Egli D, Jasin M, Keeney S.

PLoS Genet. 2013 Nov;9(11):e1003945. doi: 10.1371/journal.pgen.1003945. Epub 2013 Nov 7.

44.

β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.

Shang L, Hua H, Foo K, Martinez H, Watanabe K, Zimmer M, Kahler DJ, Freeby M, Chung W, LeDuc C, Goland R, Leibel RL, Egli D.

Diabetes. 2014 Mar;63(3):923-33. doi: 10.2337/db13-0717. Epub 2013 Nov 13.

45.

Dietary practices in pyridoxine non-responsive homocystinuria: a European survey.

Adam S, Almeida MF, Carbasius Weber E, Champion H, Chan H, Daly A, Dixon M, Dokoupil K, Egli D, Evans S, Eyskens F, Faria A, Ferguson C, Hallam P, Heddrich-Ellerbrok M, Jacobs J, Jankowski C, Lachmann R, Lilje R, Link R, Lowry S, Luyten K, MacDonald A, Maritz C, Martins E, Meyer U, Müller E, Murphy E, Robertson LV, Rocha JC, Saruggia I, Schick P, Stafford J, Stoelen L, Terry A, Thom R, van den Hurk T, van Rijn M, van Teefelen-Heithoff A, Webster D, White FJ, Wildgoose J, Zweers H.

Mol Genet Metab. 2013 Dec;110(4):454-9. doi: 10.1016/j.ymgme.2013.10.003. Epub 2013 Oct 10.

PMID:
24206934
46.

Connecting the cell cycle with cellular identity.

Chia G, Egli D.

Cell Reprogram. 2013 Oct;15(5):356-66. doi: 10.1089/cell.2013.0041. Review.

PMID:
24073943
47.

iPSC-derived β cells model diabetes due to glucokinase deficiency.

Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, Leduc C, Chung WK, Goland R, Leibel RL, Egli D.

J Clin Invest. 2013 Jul;123(7):3146-53. doi: 10.1172/JCI67638. Epub 2013 Jun 17. Retraction in: J Clin Invest. 2017 Mar 1;127(3):1115.

48.

Tying replication to cell identity.

Egli D, Le Bin GC.

Nat Rev Mol Cell Biol. 2013 Jun;14(6):326. doi: 10.1038/nrm3593. No abstract available.

PMID:
23698578
49.

Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting.

Kahler DJ, Ahmad FS, Ritz A, Hua H, Moroziewicz DN, Sproul AA, Dusenberry CR, Shang L, Paull D, Zimmer M, Weiss KA, Egli D, Noggle SA.

PLoS One. 2013;8(3):e59867. doi: 10.1371/journal.pone.0059867. Epub 2013 Mar 29.

50.

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants.

Paull D, Emmanuele V, Weiss KA, Treff N, Stewart L, Hua H, Zimmer M, Kahler DJ, Goland RS, Noggle SA, Prosser R, Hirano M, Sauer MV, Egli D.

Nature. 2013 Jan 31;493(7434):632-7. doi: 10.1038/nature11800. Epub 2012 Dec 19.

PMID:
23254936

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