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Items: 1 to 50 of 133

1.

The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis.

Jankute M, Alderwick LJ, Moorey AR, Joe M, Gurcha SS, Eggeling L, Lowary TL, Dell A, Pang PC, Yang T, Haslam S, Besra GS.

Cell Surf. 2018 Jun;2:38-53. doi: 10.1016/j.tcsw.2018.06.003.

2.

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core.

Alderwick LJ, Birch HL, Krumbach K, Bott M, Eggeling L, Besra GS.

Cell Surf. 2018 Mar;1:2-14. doi: 10.1016/j.tcsw.2017.10.001.

3.

Novel Technologies for Optimal Strain Breeding.

Bott M, Eggeling L.

Adv Biochem Eng Biotechnol. 2017;159:227-254. doi: 10.1007/10_2016_33. Review.

PMID:
27872965
4.

Exporters for Production of Amino Acids and Other Small Molecules.

Eggeling L.

Adv Biochem Eng Biotechnol. 2017;159:199-225. doi: 10.1007/10_2016_32. Review.

PMID:
27832297
5.

Mutations in MurE, the essential UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase of Corynebacterium glutamicum: effect on L-lysine formation and analysis of systemic consequences.

Hochheim J, Kranz A, Krumbach K, Sokolowsky S, Eggeling L, Noack S, Bocola M, Bott M, Marienhagen J.

Biotechnol Lett. 2017 Feb;39(2):283-288. doi: 10.1007/s10529-016-2243-8. Epub 2016 Oct 25.

PMID:
27783176
6.

Formation of xylitol and xylitol-5-phosphate and its impact on growth of d-xylose-utilizing Corynebacterium glutamicum strains.

Radek A, Müller MF, Gätgens J, Eggeling L, Krumbach K, Marienhagen J, Noack S.

J Biotechnol. 2016 Aug 10;231:160-166. doi: 10.1016/j.jbiotec.2016.06.009. Epub 2016 Jun 11.

PMID:
27297548
7.

A giant market and a powerful metabolism: L-lysine provided by Corynebacterium glutamicum.

Eggeling L, Bott M.

Appl Microbiol Biotechnol. 2015 Apr;99(8):3387-94. doi: 10.1007/s00253-015-6508-2. Epub 2015 Mar 13. Review.

PMID:
25761623
8.

Novel screening methods--biosensors.

Eggeling L, Bott M, Marienhagen J.

Curr Opin Biotechnol. 2015 Dec;35:30-6. doi: 10.1016/j.copbio.2014.12.021. Epub 2015 Jan 9. Review.

PMID:
25578902
9.

Acyl-CoA sensing by FasR to adjust fatty acid synthesis in Corynebacterium glutamicum.

Irzik K, van Ooyen J, Gätgens J, Krumbach K, Bott M, Eggeling L.

J Biotechnol. 2014 Dec 20;192 Pt A:96-101.

PMID:
25449109
10.

The contest for precursors: channelling L-isoleucine synthesis in Corynebacterium glutamicum without byproduct formation.

Vogt M, Krumbach K, Bang WG, van Ooyen J, Noack S, Klein B, Bott M, Eggeling L.

Appl Microbiol Biotechnol. 2015 Jan;99(2):791-800. doi: 10.1007/s00253-014-6109-5. Epub 2014 Oct 10.

PMID:
25301583
11.

Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model.

Raasch K, Bocola M, Labahn J, Leitner A, Eggeling L, Bott M.

J Biotechnol. 2014 Dec 10;191:99-105. doi: 10.1016/j.jbiotec.2014.05.023. Epub 2014 Jun 4.

PMID:
24905147
12.

Pupylated proteins in Corynebacterium glutamicum revealed by MudPIT analysis.

Küberl A, Fränzel B, Eggeling L, Polen T, Wolters DA, Bott M.

Proteomics. 2014 Jun;14(12):1531-42. doi: 10.1002/pmic.201300531. Epub 2014 May 16.

PMID:
24737727
13.

Looking for the pick of the bunch: high-throughput screening of producing microorganisms with biosensors.

Schallmey M, Frunzke J, Eggeling L, Marienhagen J.

Curr Opin Biotechnol. 2014 Apr;26:148-54. doi: 10.1016/j.copbio.2014.01.005. Epub 2014 Jan 28. Review.

14.

Benzothiazinones mediate killing of Corynebacterineae by blocking decaprenyl phosphate recycling involved in cell wall biosynthesis.

Grover S, Alderwick LJ, Mishra AK, Krumbach K, Marienhagen J, Eggeling L, Bhatt A, Besra GS.

J Biol Chem. 2014 Feb 28;289(9):6177-87. doi: 10.1074/jbc.M113.522623. Epub 2014 Jan 20.

15.

Pushing product formation to its limit: metabolic engineering of Corynebacterium glutamicum for L-leucine overproduction.

Vogt M, Haas S, Klaffl S, Polen T, Eggeling L, van Ooyen J, Bott M.

Metab Eng. 2014 Mar;22:40-52. doi: 10.1016/j.ymben.2013.12.001. Epub 2013 Dec 11.

PMID:
24333966
16.

SoxR as a single-cell biosensor for NADPH-consuming enzymes in Escherichia coli.

Siedler S, Schendzielorz G, Binder S, Eggeling L, Bringer S, Bott M.

ACS Synth Biol. 2014 Jan 17;3(1):41-7. doi: 10.1021/sb400110j. Epub 2013 Dec 9.

PMID:
24283989
17.

Visualization of imbalances in sulfur assimilation and synthesis of sulfur-containing amino acids at the single-cell level.

Hoffmann K, Grünberger A, Lausberg F, Bott M, Eggeling L.

Appl Environ Microbiol. 2013 Nov;79(21):6730-6. doi: 10.1128/AEM.01804-13. Epub 2013 Aug 30.

18.

Taking control over control: use of product sensing in single cells to remove flux control at key enzymes in biosynthesis pathways.

Schendzielorz G, Dippong M, Grünberger A, Kohlheyer D, Yoshida A, Binder S, Nishiyama C, Nishiyama M, Bott M, Eggeling L.

ACS Synth Biol. 2014 Jan 17;3(1):21-9. doi: 10.1021/sb400059y. Epub 2013 Jul 15.

PMID:
23829416
19.

Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation.

Binder S, Siedler S, Marienhagen J, Bott M, Eggeling L.

Nucleic Acids Res. 2013 Jul;41(12):6360-9. doi: 10.1093/nar/gkt312. Epub 2013 Apr 28.

20.

TCA cycle involved enzymes SucA and Kgd, as well as MenD: efficient biocatalysts for asymmetric C-C bond formation.

Beigi M, Waltzer S, Fries A, Eggeling L, Sprenger GA, Müller M.

Org Lett. 2013 Feb 1;15(3):452-5. doi: 10.1021/ol3031186. Epub 2013 Jan 14.

PMID:
23317369
21.

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.

Tatituri RV, Watts GF, Bhowruth V, Barton N, Rothchild A, Hsu FF, Almeida CF, Cox LR, Eggeling L, Cardell S, Rossjohn J, Godfrey DI, Behar SM, Besra GS, Brenner MB, Brigl M.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1827-32. doi: 10.1073/pnas.1220601110. Epub 2013 Jan 10.

22.

Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation.

Mishra AK, Alves JE, Krumbach K, Nigou J, Castro AG, Geurtsen J, Eggeling L, Saraiva M, Besra GS.

J Biol Chem. 2012 Dec 28;287(53):44173-83. doi: 10.1074/jbc.M112.402396. Epub 2012 Nov 9.

23.

The ppm operon is essential for acylation and glycosylation of lipoproteins in Corynebacterium glutamicum.

Mohiman N, Argentini M, Batt SM, Cornu D, Masi M, Eggeling L, Besra G, Bayan N.

PLoS One. 2012;7(9):e46225. doi: 10.1371/journal.pone.0046225. Epub 2012 Sep 28.

24.

Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments.

Grünberger A, van Ooyen J, Paczia N, Rohe P, Schiendzielorz G, Eggeling L, Wiechert W, Kohlheyer D, Noack S.

Biotechnol Bioeng. 2013 Jan;110(1):220-8. doi: 10.1002/bit.24616. Epub 2012 Aug 13.

PMID:
22890752
25.

Corynebacterium glutamicum harbours a molybdenum cofactor-dependent formate dehydrogenase which alleviates growth inhibition in the presence of formate.

Witthoff S, Eggeling L, Bott M, Polen T.

Microbiology. 2012 Sep;158(Pt 9):2428-39. doi: 10.1099/mic.0.059196-0. Epub 2012 Jul 5.

PMID:
22767548
26.

Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.

Batt SM, Jabeen T, Bhowruth V, Quill L, Lund PA, Eggeling L, Alderwick LJ, Fütterer K, Besra GS.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11354-9. doi: 10.1073/pnas.1205735109. Epub 2012 Jun 25.

27.

A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level.

Binder S, Schendzielorz G, Stäbler N, Krumbach K, Hoffmann K, Bott M, Eggeling L.

Genome Biol. 2012 May 28;13(5):R40. doi: 10.1186/gb-2012-13-5-r40.

28.

A tetracycline inducible expression vector for Corynebacterium glutamicum allowing tightly regulable gene expression.

Lausberg F, Chattopadhyay AR, Heyer A, Eggeling L, Freudl R.

Plasmid. 2012 Sep;68(2):142-7. doi: 10.1016/j.plasmid.2012.05.001. Epub 2012 May 12.

PMID:
22587824
29.

Deletion of manC in Corynebacterium glutamicum results in a phospho-myo-inositol mannoside- and lipoglycan-deficient mutant.

Mishra AK, Krumbach K, Rittmann D, Batt SM, Lee OY, De S, Frunzke J, Besra GS, Eggeling L.

Microbiology. 2012 Jul;158(Pt 7):1908-17. doi: 10.1099/mic.0.057653-0. Epub 2012 Apr 26.

PMID:
22539165
30.

MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteria.

Varela C, Rittmann D, Singh A, Krumbach K, Bhatt K, Eggeling L, Besra GS, Bhatt A.

Chem Biol. 2012 Apr 20;19(4):498-506. doi: 10.1016/j.chembiol.2012.03.006.

31.

A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.

Grünberger A, Paczia N, Probst C, Schendzielorz G, Eggeling L, Noack S, Wiechert W, Kohlheyer D.

Lab Chip. 2012 May 8;12(11):2060-8. doi: 10.1039/c2lc40156h. Epub 2012 Apr 17.

PMID:
22511122
32.

Improved L-lysine production with Corynebacterium glutamicum and systemic insight into citrate synthase flux and activity.

van Ooyen J, Noack S, Bott M, Reth A, Eggeling L.

Biotechnol Bioeng. 2012 Aug;109(8):2070-81. doi: 10.1002/bit.24486. Epub 2012 Mar 22.

PMID:
22392073
33.

The cytotoxic early protein 77 of mycobacteriophage L5 interacts with MSMEG_3532, an L-serine dehydratase of Mycobacterium smegmatis.

Rybniker J, Krumbach K, van Gumpel E, Plum G, Eggeling L, Hartmann P.

J Basic Microbiol. 2011 Oct;51(5):515-22. doi: 10.1002/jobm.201000446. Epub 2011 Jun 9.

PMID:
21656815
34.

Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching.

Mishra AK, Krumbach K, Rittmann D, Appelmelk B, Pathak V, Pathak AK, Nigou J, Geurtsen J, Eggeling L, Besra GS.

Mol Microbiol. 2011 Jun;80(5):1241-59. doi: 10.1111/j.1365-2958.2011.07640.x. Epub 2011 Apr 4.

35.

The C-terminal domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC is a lectin-like carbohydrate binding module.

Alderwick LJ, Lloyd GS, Ghadbane H, May JW, Bhatt A, Eggeling L, Fütterer K, Besra GS.

PLoS Pathog. 2011 Feb;7(2):e1001299. doi: 10.1371/journal.ppat.1001299. Epub 2011 Feb 24.

36.

Corynebacterium glutamicum as a host for synthesis and export of D-Amino Acids.

Stäbler N, Oikawa T, Bott M, Eggeling L.

J Bacteriol. 2011 Apr;193(7):1702-9. doi: 10.1128/JB.01295-10. Epub 2011 Jan 21.

37.

Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase.

Alderwick LJ, Lloyd GS, Lloyd AJ, Lovering AL, Eggeling L, Besra GS.

Glycobiology. 2011 Apr;21(4):410-25. doi: 10.1093/glycob/cwq173. Epub 2010 Nov 2.

38.

The TetR-type transcriptional regulator FasR of Corynebacterium glutamicum controls genes of lipid synthesis during growth on acetate.

Nickel J, Irzik K, van Ooyen J, Eggeling L.

Mol Microbiol. 2010 Oct;78(1):253-65. doi: 10.1111/j.1365-2958.2010.07337.x.

39.

Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.

Batt SM, Jabeen T, Mishra AK, Veerapen N, Krumbach K, Eggeling L, Besra GS, Fütterer K.

J Biol Chem. 2010 Nov 26;285(48):37741-52. doi: 10.1074/jbc.M110.165407. Epub 2010 Sep 15.

40.

The E2 domain of OdhA of Corynebacterium glutamicum has succinyltransferase activity dependent on lipoyl residues of the acetyltransferase AceF.

Hoffelder M, Raasch K, van Ooyen J, Eggeling L.

J Bacteriol. 2010 Oct;192(19):5203-11. doi: 10.1128/JB.00597-10. Epub 2010 Jul 30.

41.

Citrate synthase in Corynebacterium glutamicum is encoded by two gltA transcripts which are controlled by RamA, RamB, and GlxR.

van Ooyen J, Emer D, Bussmann M, Bott M, Eikmanns BJ, Eggeling L.

J Biotechnol. 2011 Jul 10;154(2-3):140-8. doi: 10.1016/j.jbiotec.2010.07.004. Epub 2010 Jul 12.

PMID:
20630483
42.

The FHA domain of OdhI interacts with the carboxyterminal 2-oxoglutarate dehydrogenase domain of OdhA in Corynebacterium glutamicum.

Krawczyk S, Raasch K, Schultz C, Hoffelder M, Eggeling L, Bott M.

FEBS Lett. 2010 Apr 16;584(8):1463-8. doi: 10.1016/j.febslet.2010.03.028. Epub 2010 Mar 19.

43.

A truncated lipoglycan from mycobacteria with altered immunological properties.

Birch HL, Alderwick LJ, Appelmelk BJ, Maaskant J, Bhatt A, Singh A, Nigou J, Eggeling L, Geurtsen J, Besra GS.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2634-9. doi: 10.1073/pnas.0915082107. Epub 2010 Jan 25.

44.

Identification of a terminal rhamnopyranosyltransferase (RptA) involved in Corynebacterium glutamicum cell wall biosynthesis.

Birch HL, Alderwick LJ, Rittmann D, Krumbach K, Etterich H, Grzegorzewicz A, McNeil MR, Eggeling L, Besra GS.

J Bacteriol. 2009 Aug;191(15):4879-87. doi: 10.1128/JB.00296-09. Epub 2009 May 29.

45.
46.

A periplasmic, pyridoxal-5'-phosphate-dependent amino acid racemase in Pseudomonas taetrolens.

Matsui D, Oikawa T, Arakawa N, Osumi S, Lausberg F, Stäbler N, Freudl R, Eggeling L.

Appl Microbiol Biotechnol. 2009 Jul;83(6):1045-54. doi: 10.1007/s00253-009-1942-7. Epub 2009 Mar 20.

PMID:
19300994
47.

Formation and metabolism of methylmalonyl coenzyme A in Corynebacterium glutamicum.

Botella L, Lindley ND, Eggeling L.

J Bacteriol. 2009 Apr;191(8):2899-901. doi: 10.1128/JB.01756-08. Epub 2009 Feb 20.

48.

The serine hydroxymethyltransferase gene glyA in Corynebacterium glutamicum is controlled by GlyR.

Schweitzer JE, Stolz M, Diesveld R, Etterich H, Eggeling L.

J Biotechnol. 2009 Feb 5;139(3):214-21. doi: 10.1016/j.jbiotec.2008.12.008. Epub 2008 Dec 16.

PMID:
19124047
49.

Myo-inositol facilitators IolT1 and IolT2 enhance D-mannitol formation from D-fructose in Corynebacterium glutamicum.

Bäumchen C, Krings E, Bringer S, Eggeling L, Sahm H.

FEMS Microbiol Lett. 2009 Jan;290(2):227-35. doi: 10.1111/j.1574-6968.2008.01425.x. Epub 2008 Nov 20.

50.

Metabolic function of Corynebacterium glutamicum aminotransferases AlaT and AvtA and impact on L-valine production.

Marienhagen J, Eggeling L.

Appl Environ Microbiol. 2008 Dec;74(24):7457-62. doi: 10.1128/AEM.01025-08. Epub 2008 Oct 17.

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