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Items: 1 to 50 of 55

1.

ROCK Inhibition Promotes the Development of Chondrogenic Tissue by Improved Mass Transport.

Wang KC, Egelhoff TT, Caplan AI, Welter JF, Baskaran H.

Tissue Eng Part A. 2018 Aug;24(15-16):1218-1227. doi: 10.1089/ten.TEA.2017.0438. Epub 2018 Apr 23.

2.

Myosin IIA Heavy Chain Phosphorylation Mediates Adhesion Maturation and Protrusion in Three Dimensions.

Rai V, Thomas DG, Beach JR, Egelhoff TT.

J Biol Chem. 2017 Feb 24;292(8):3099-3111. doi: 10.1074/jbc.M116.733402. Epub 2017 Jan 4.

3.

Transforming Growth Factor-β Is an Upstream Regulator of Mammalian Target of Rapamycin Complex 2-Dependent Bladder Cancer Cell Migration and Invasion.

Gupta S, Hau AM, Al-Ahmadie HA, Harwalkar J, Shoskes AC, Elson P, Beach JR, Hussey GS, Schiemann WP, Egelhoff TT, Howe PH, Hansel DE.

Am J Pathol. 2016 May;186(5):1351-60. doi: 10.1016/j.ajpath.2016.01.008. Epub 2016 Mar 14.

4.

Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype.

Southern BD, Grove LM, Rahaman SO, Abraham S, Scheraga RG, Niese KA, Sun H, Herzog EL, Liu F, Tschumperlin DJ, Egelhoff TT, Rosenfeld SS, Olman MA.

J Biol Chem. 2016 Mar 18;291(12):6083-95. doi: 10.1074/jbc.M115.712380. Epub 2016 Jan 13.

5.

Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion.

Thomas DG, Yenepalli A, Denais CM, Rape A, Beach JR, Wang YL, Schiemann WP, Baskaran H, Lammerding J, Egelhoff TT.

J Cell Biol. 2015 Aug 17;210(4):583-94. doi: 10.1083/jcb.201502039. Epub 2015 Aug 10.

6.

Rac1-dependent phosphorylation and focal adhesion recruitment of myosin IIA regulates migration and mechanosensing.

Pasapera AM, Plotnikov SV, Fischer RS, Case LB, Egelhoff TT, Waterman CM.

Curr Biol. 2015 Jan 19;25(2):175-186. doi: 10.1016/j.cub.2014.11.043. Epub 2014 Dec 24.

7.

Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion.

Gupta S, Hau AM, Beach JR, Harwalker J, Mantuano E, Gonias SL, Egelhoff TT, Hansel DE.

PLoS One. 2013 Nov 27;8(11):e81081. doi: 10.1371/journal.pone.0081081. eCollection 2013.

8.

Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality.

Crish J, Conti MA, Sakai T, Adelstein RS, Egelhoff TT.

Dev Biol. 2013 Oct 1;382(1):136-48. doi: 10.1016/j.ydbio.2013.07.017. Epub 2013 Jul 30.

9.

Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression.

Chandrasekharan UM, Dechert L, Davidson UI, Waitkus M, Mavrakis L, Lyons K, Beach JR, Li X, Egelhoff TT, Fox PL, DiCorleto PE.

Sci Signal. 2013 Jul 16;6(284):ra60. doi: 10.1126/scisignal.2003743.

10.

Myosin heavy chain kinases play essential roles in Ca2+, but not cAMP, chemotaxis and the natural aggregation of Dictyostelium discoideum.

Wessels D, Lusche DF, Steimle PA, Scherer A, Kuhl S, Wood K, Hanson B, Egelhoff TT, Soll DR.

J Cell Sci. 2012 Oct 15;125(Pt 20):4934-44. doi: 10.1242/jcs.112474. Epub 2012 Aug 16.

11.

Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells.

Beach JR, Licate LS, Crish JF, Egelhoff TT.

BMC Cell Biol. 2011 Dec 2;12:52. doi: 10.1186/1471-2121-12-52. Erratum in: BMC Cell Biol. 2012;13:11.

12.

Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition.

Beach JR, Hussey GS, Miller TE, Chaudhury A, Patel P, Monslow J, Zheng Q, Keri RA, Reizes O, Bresnick AR, Howe PH, Egelhoff TT.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):17991-6. doi: 10.1073/pnas.1106499108. Epub 2011 Oct 24.

13.

Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation.

Wang Y, Steimle PA, Ren Y, Ross CA, Robinson DN, Egelhoff TT, Sesaki H, Iijima M.

Mol Biol Cell. 2011 Jul 1;22(13):2270-81. doi: 10.1091/mbc.E10-11-0926. Epub 2011 May 11.

14.

Role of B regulatory subunits of protein phosphatase type 2A in myosin II assembly control in Dictyostelium discoideum.

Rai V, Egelhoff TT.

Eukaryot Cell. 2011 Apr;10(4):604-10. doi: 10.1128/EC.00296-10. Epub 2011 Feb 25.

15.

A proteomic study of myosin II motor proteins during tumor cell migration.

Betapudi V, Gokulrangan G, Chance MR, Egelhoff TT.

J Mol Biol. 2011 Apr 15;407(5):673-86. doi: 10.1016/j.jmb.2011.02.010. Epub 2011 Feb 18.

16.

A microfluidic imaging chamber for the direct observation of chemotactic transmigration.

Breckenridge MT, Egelhoff TT, Baskaran H.

Biomed Microdevices. 2010 Jun;12(3):543-53. doi: 10.1007/s10544-010-9411-8.

17.

Roles of an unconventional protein kinase and myosin II in amoeba osmotic shock responses.

Betapudi V, Egelhoff TT.

Traffic. 2009 Dec;10(12):1773-84. doi: 10.1111/j.1600-0854.2009.00992.x. Epub 2009 Sep 22.

18.

Myosin II recruitment during cytokinesis independent of centralspindlin-mediated phosphorylation.

Beach JR, Egelhoff TT.

J Biol Chem. 2009 Oct 2;284(40):27377-83. doi: 10.1074/jbc.M109.028316. Epub 2009 Aug 6.

19.

Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells.

Breckenridge MT, Dulyaninova NG, Egelhoff TT.

Mol Biol Cell. 2009 Jan;20(1):338-47. doi: 10.1091/mbc.E08-04-0372. Epub 2008 Oct 29.

20.

Cardiac myocyte cytokinesis: The contractile ring is the thing.

Egelhoff TT, Fisher SA.

J Mol Cell Cardiol. 2006 Oct;41(4):592-4. Epub 2006 Aug 24. No abstract available.

PMID:
16934289
21.
22.

Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium.

Yumura S, Yoshida M, Betapudi V, Licate LS, Iwadate Y, Nagasaki A, Uyeda TQ, Egelhoff TT.

Mol Biol Cell. 2005 Sep;16(9):4256-66. Epub 2005 Jun 29.

24.
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26.

Signaling pathways regulating Dictyostelium myosin II.

De la Roche MA, Smith JL, Betapudi V, Egelhoff TT, Côté GP.

J Muscle Res Cell Motil. 2002;23(7-8):703-18. Review.

PMID:
12952069
27.
28.

Dictyostelium discoideum has a single diacylglycerol kinase gene with similarity to mammalian theta isoforms.

De La Roche MA, Smith JL, Rico M, Carrasco S, Merida I, Licate L, Côté GP, Egelhoff TT.

Biochem J. 2002 Dec 15;368(Pt 3):809-15.

29.
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31.

Recruitment of a myosin heavy chain kinase to actin-rich protrusions in Dictyostelium.

Steimle PA, Yumura S, Côté GP, Medley QG, Polyakov MV, Leppert B, Egelhoff TT.

Curr Biol. 2001 May 1;11(9):708-13.

32.

Specific phosphorylation of threonine by the Dictyostelium myosin II heavy chain kinase family.

Luo X, Crawley SW, Steimle PA, Egelhoff TT, Cote GP.

J Biol Chem. 2001 May 25;276(21):17836-43. Epub 2001 Feb 20.

33.

WD repeat domains target dictyostelium myosin heavy chain kinases by binding directly to myosin filaments.

Steimle PA, Naismith T, Licate L, Egelhoff TT.

J Biol Chem. 2001 Mar 2;276(9):6853-60. Epub 2000 Dec 5.

34.

Green fluorescent protein and epitope tag fusion vectors for Dictyostelium discoideum.

Levi S, Polyakov M, Egelhoff TT.

Plasmid. 2000 Nov;44(3):231-8.

PMID:
11078649
35.
36.
38.

Identification of a protein kinase from Dictyostelium with homology to the novel catalytic domain of myosin heavy chain kinase A.

Clancy CE, Mendoza MG, Naismith TV, Kolman MF, Egelhoff TT.

J Biol Chem. 1997 May 2;272(18):11812-5.

39.

Mapping of the novel protein kinase catalytic domain of Dictyostelium myosin II heavy chain kinase A.

Côté GP, Luo X, Murphy MB, Egelhoff TT.

J Biol Chem. 1997 Mar 14;272(11):6846-9.

40.

Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by Cdc42 and Rac.

Lee SF, Egelhoff TT, Mahasneh A, Côté GP.

J Biol Chem. 1996 Oct 25;271(43):27044-8.

41.

Myosin-based cortical tension in Dictyostelium resolved into heavy and light chain-regulated components.

Egelhoff TT, Naismith TV, Brozovich FV.

J Muscle Res Cell Motil. 1996 Apr;17(2):269-74.

PMID:
8793728
42.
44.
45.
46.

Molecular genetics of cell migration: Dictyostelium as a model system.

Egelhoff TT, Spudich JA.

Trends Genet. 1991 May;7(5):161-6. Review.

PMID:
2068788
48.

Molecular genetic tools for study of the cytoskeleton in Dictyostelium.

Egelhoff TT, Titus MA, Manstein DJ, Ruppel KM, Spudich JA.

Methods Enzymol. 1991;196:319-34. No abstract available.

PMID:
2034127
49.

Complementation of myosin null mutants in Dictyostelium discoideum by direct functional selection.

Egelhoff TT, Manstein DJ, Spudich JA.

Dev Biol. 1990 Feb;137(2):359-67.

PMID:
2406175
50.

Purification of a functional recombinant myosin fragment from Dictyostelium discoideum.

Ruppel KM, Egelhoff TT, Spudich JA.

Ann N Y Acad Sci. 1990;582:147-55. No abstract available.

PMID:
2141452

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