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Items: 1 to 50 of 102

1.

Tumours pick the path to cancer inflammation.

Maiorino L, Egeblad M.

Nat Cell Biol. 2019 Sep;21(9):1055-1057. doi: 10.1038/s41556-019-0386-2. No abstract available.

PMID:
31451769
2.

Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod.

Rozenblit M, Hendrickx W, Heguy A, Chiriboga L, Loomis C, Ray K, Darvishian F, Egeblad M, Demaria S, Marincola FM, Bedognetti D, Adams S.

Sci Rep. 2019 Jun 12;9(1):8572. doi: 10.1038/s41598-019-42784-9.

3.

Sticking together helps cancer to spread.

Egeblad M, de Visser KE.

Nature. 2019 Feb;566(7745):459-460. doi: 10.1038/d41586-019-00341-4. No abstract available.

PMID:
30809048
4.

Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.

Albrengues J, Shields MA, Ng D, Park CG, Ambrico A, Poindexter ME, Upadhyay P, Uyeminami DL, Pommier A, Küttner V, Bružas E, Maiorino L, Bautista C, Carmona EM, Gimotty PA, Fearon DT, Chang K, Lyons SK, Pinkerton KE, Trotman LC, Goldberg MS, Yeh JT, Egeblad M.

Science. 2018 Sep 28;361(6409). pii: eaao4227. doi: 10.1126/science.aao4227.

5.

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.

Huang YH, Klingbeil O, He XY, Wu XS, Arun G, Lu B, Somerville TDD, Milazzo JP, Wilkinson JE, Demerdash OE, Spector DL, Egeblad M, Shi J, Vakoc CR.

Genes Dev. 2018 Jul 1;32(13-14):915-928. doi: 10.1101/gad.314815.118. Epub 2018 Jun 26.

6.

Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases.

Pommier A, Anaparthy N, Memos N, Kelley ZL, Gouronnec A, Yan R, Auffray C, Albrengues J, Egeblad M, Iacobuzio-Donahue CA, Lyons SK, Fearon DT.

Science. 2018 Jun 15;360(6394). pii: eaao4908. doi: 10.1126/science.aao4908. Epub 2018 May 17.

7.

Bone Talk: Activated Osteoblasts Promote Lung Cancer Growth.

Bružas E, Egeblad M.

Trends Mol Med. 2018 Mar;24(3):237-239. doi: 10.1016/j.molmed.2018.01.007. Epub 2018 Feb 3.

PMID:
29402707
8.

Re-cyclin' Cell-Cycle Components to Make NETs.

Albrengues J, Wysocki RW, Maiorino L, Egeblad M.

Dev Cell. 2017 Nov 20;43(4):379-380. doi: 10.1016/j.devcel.2017.11.002. Review.

9.

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis.

Roe JS, Hwang CI, Somerville TDD, Milazzo JP, Lee EJ, Da Silva B, Maiorino L, Tiriac H, Young CM, Miyabayashi K, Filippini D, Creighton B, Burkhart RA, Buscaglia JM, Kim EJ, Grem JL, Lazenby AJ, Grunkemeyer JA, Hollingsworth MA, Grandgenett PM, Egeblad M, Park Y, Tuveson DA, Vakoc CR.

Cell. 2017 Aug 24;170(5):875-888.e20. doi: 10.1016/j.cell.2017.07.007. Epub 2017 Jul 27.

10.

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.

Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA.

J Exp Med. 2017 Mar 6;214(3):579-596. doi: 10.1084/jem.20162024. Epub 2017 Feb 23.

11.

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth.

Perurena N, Zandueta C, Martínez-Canarias S, Moreno H, Vicent S, Almeida AS, Guruceaga E, Gomis RR, Santisteban M, Egeblad M, Hermida J, Lecanda F.

J Hematol Oncol. 2017 Jan 19;10(1):23. doi: 10.1186/s13045-017-0399-x.

12.

Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps.

Park J, Wysocki RW, Amoozgar Z, Maiorino L, Fein MR, Jorns J, Schott AF, Kinugasa-Katayama Y, Lee Y, Won NH, Nakasone ES, Hearn SA, Küttner V, Qiu J, Almeida AS, Perurena N, Kessenbrock K, Goldberg MS, Egeblad M.

Sci Transl Med. 2016 Oct 19;8(361):361ra138.

13.

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.

Arun G, Diermeier S, Akerman M, Chang KC, Wilkinson JE, Hearn S, Kim Y, MacLeod AR, Krainer AR, Norton L, Brogi E, Egeblad M, Spector DL.

Genes Dev. 2016 Jan 1;30(1):34-51. doi: 10.1101/gad.270959.115. Epub 2015 Dec 23.

14.

Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer.

Park JH, Rasch MG, Qiu J, Lund IK, Egeblad M.

Neoplasia. 2015 May;17(5):421-33. doi: 10.1016/j.neo.2015.04.003.

15.

Cancer: Sugar-coated cell signalling.

Ewald AJ, Egeblad M.

Nature. 2014 Jul 17;511(7509):298-9. doi: 10.1038/nature13506. Epub 2014 Jun 25. No abstract available.

PMID:
25030162
16.

Q&A: Mikala Egeblad on tumor microenvironment.

Egeblad M, Rose S.

Cancer Discov. 2014 May;4(5):503. doi: 10.1158/2159-8290.CD-ND2014-007. Epub 2014 Apr 17.

17.

System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity.

Rajaram M, Li J, Egeblad M, Powers RS.

PLoS Genet. 2013;9(9):e1003789. doi: 10.1371/journal.pgen.1003789. Epub 2013 Sep 19.

18.

Recapitulating human cancer in a mouse.

Chin L, de Sauvage F, Egeblad M, Olive KP, Tuveson D, Weiss W.

Nat Biotechnol. 2013 May;31(5):392-5. doi: 10.1038/nbt.2575. No abstract available.

PMID:
23657389
19.

Caught in the act: revealing the metastatic process by live imaging.

Fein MR, Egeblad M.

Dis Model Mech. 2013 May;6(3):580-93. doi: 10.1242/dmm.009282. Review.

20.

Live imaging of drug responses in the tumor microenvironment in mouse models of breast cancer.

Nakasone ES, Askautrud HA, Egeblad M.

J Vis Exp. 2013 Mar 24;(73):e50088. doi: 10.3791/50088.

21.

Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance.

Nakasone ES, Askautrud HA, Kees T, Park JH, Plaks V, Ewald AJ, Fein M, Rasch MG, Tan YX, Qiu J, Park J, Sinha P, Bissell MJ, Frengen E, Werb Z, Egeblad M.

Cancer Cell. 2012 Apr 17;21(4):488-503. doi: 10.1016/j.ccr.2012.02.017.

22.

Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells.

Engelhardt JJ, Boldajipour B, Beemiller P, Pandurangi P, Sorensen C, Werb Z, Egeblad M, Krummel MF.

Cancer Cell. 2012 Mar 20;21(3):402-17. doi: 10.1016/j.ccr.2012.01.008.

23.

Innate immune cells in breast cancer--from villains to heroes?

Kees T, Egeblad M.

J Mammary Gland Biol Neoplasia. 2011 Sep;16(3):189-203. doi: 10.1007/s10911-011-9224-2. Epub 2011 Jul 26. Review.

PMID:
21789554
24.

Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy.

Ewald AJ, Werb Z, Egeblad M.

Cold Spring Harb Protoc. 2011 Feb 1;2011(2):pdb.top97. doi: 10.1101/pdb.top97. No abstract available.

25.

Monitoring of vital signs for long-term survival of mice under anesthesia.

Ewald AJ, Werb Z, Egeblad M.

Cold Spring Harb Protoc. 2011 Feb 1;2011(2):pdb.prot5563. doi: 10.1101/pdb.prot5563. No abstract available.

26.

Preparation of mice for long-term intravital imaging of the mammary gland.

Ewald AJ, Werb Z, Egeblad M.

Cold Spring Harb Protoc. 2011 Feb 1;2011(2):pdb.prot5562. doi: 10.1101/pdb.prot5562. No abstract available.

27.

Dynamic interplay between the collagen scaffold and tumor evolution.

Egeblad M, Rasch MG, Weaver VM.

Curr Opin Cell Biol. 2010 Oct;22(5):697-706. doi: 10.1016/j.ceb.2010.08.015. Epub 2010 Sep 6. Review.

28.

Tumors as organs: complex tissues that interface with the entire organism.

Egeblad M, Nakasone ES, Werb Z.

Dev Cell. 2010 Jun 15;18(6):884-901. doi: 10.1016/j.devcel.2010.05.012. Review.

29.

Stromal regulation of vessel stability by MMP14 and TGFbeta.

Sounni NE, Dehne K, van Kempen L, Egeblad M, Affara NI, Cuevas I, Wiesen J, Junankar S, Korets L, Lee J, Shen J, Morrison CJ, Overall CM, Krane SM, Werb Z, Boudreau N, Coussens LM.

Dis Model Mech. 2010 May-Jun;3(5-6):317-32. doi: 10.1242/dmm.003863. Epub 2010 Mar 11.

30.

Matrix crosslinking forces tumor progression by enhancing integrin signaling.

Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM.

Cell. 2009 Nov 25;139(5):891-906. doi: 10.1016/j.cell.2009.10.027.

31.

Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy.

Egeblad M, Ewald AJ, Askautrud HA, Truitt ML, Welm BE, Bainbridge E, Peeters G, Krummel MF, Werb Z.

Dis Model Mech. 2008 Sep-Oct;1(2-3):155-67; discussion 165. doi: 10.1242/dmm.000596. Epub 2008 Sep 18.

32.

Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression.

Nielsen BS, Egeblad M, Rank F, Askautrud HA, Pennington CJ, Pedersen TX, Christensen IJ, Edwards DR, Werb Z, Lund LR.

PLoS One. 2008 Aug 13;3(8):e2959. doi: 10.1371/journal.pone.0002959.

33.

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.

Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z.

Cancer Cell. 2008 Feb;13(2):141-52. doi: 10.1016/j.ccr.2008.01.011.

34.

Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development.

Egeblad M, Shen HC, Behonick DJ, Wilmes L, Eichten A, Korets LV, Kheradmand F, Werb Z, Coussens LM.

Dev Dyn. 2007 Jun;236(6):1683-93.

35.

The fibroblastic coconspirator in cancer progression.

Egeblad M, Littlepage LE, Werb Z.

Cold Spring Harb Symp Quant Biol. 2005;70:383-8. Review.

36.

Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. Ten years experience in Denmark.

Mellemkjaer S, Ilkjaer LB, Klaaborg KE, Christiansen CL, Severinsen IK, Nielsen-Kudsk JE, Allermand H, Egeblad M, Kristensen BO.

Scand Cardiovasc J. 2006 Feb;40(1):49-53.

PMID:
16448998
37.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.

Morimoto-Tomita M, Uchimura K, Bistrup A, Lum DH, Egeblad M, Boudreau N, Werb Z, Rosen SD.

Neoplasia. 2005 Nov;7(11):1001-10.

38.

Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth.

Määttä JA, Sundvall M, Junttila TT, Peri L, Laine VJ, Isola J, Egeblad M, Elenius K.

Mol Biol Cell. 2006 Jan;17(1):67-79. Epub 2005 Oct 26.

39.

Coevolution of cancer and stromal cellular responses.

Littlepage LE, Egeblad M, Werb Z.

Cancer Cell. 2005 Jun;7(6):499-500.

40.

Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis.

van Kempen LC, Meier F, Egeblad M, Kersten-Niessen MJ, Garbe C, Weidle UH, Van Muijen GN, Herlyn M, Bloemers HP, Swart GW.

J Invest Dermatol. 2004 May;122(5):1293-301.

41.

[Endovascular treatment of peripheral arterial obstruction].

Egeblad MR.

Ugeskr Laeger. 2004 Feb 23;166(9):794-5. Danish. No abstract available.

PMID:
15042955
42.

Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.

Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15853-8. Epub 2003 Dec 10.

43.

Ets2-dependent stromal regulation of mouse mammary tumors.

Man AK, Young LJ, Tynan JA, Lesperance J, Egeblad M, Werb Z, Hauser CA, Muller WJ, Cardiff RD, Oshima RG.

Mol Cell Biol. 2003 Dec;23(23):8614-25.

44.

New functions for the matrix metalloproteinases in cancer progression.

Egeblad M, Werb Z.

Nat Rev Cancer. 2002 Mar;2(3):161-74. Review.

PMID:
11990853
45.
46.

[Selected interventional radiologic procedures].

Nielsen DT, Egeblad MR.

Ugeskr Laeger. 2001 Aug 13;163(33):4337-40. Danish. No abstract available.

PMID:
11521564
47.

Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.

Karpanen T, Egeblad M, Karkkainen MJ, Kubo H, Ylä-Herttuala S, Jäättelä M, Alitalo K.

Cancer Res. 2001 Mar 1;61(5):1786-90.

48.

BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells.

Egeblad M, Mortensen OH, van Kempen LC, Jäättelä M.

Biochem Biophys Res Commun. 2001 Feb 16;281(1):25-31.

PMID:
11178955
49.
50.

Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family.

Larsen SS, Egeblad M, Jäättelä M, Lykkesfeldt AE.

Breast Cancer Res Treat. 1999 Nov;58(1):41-56.

PMID:
10634517

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