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Items: 1 to 50 of 187

1.

Early toll-like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodent and human brain ischaemia models.

Parada E, Casas AI, Palomino-Antolin A, Gómez-Rangel V, Rubio-Navarro A, Farré-Alins V, Narros-Fernandez P, Guerrero-Hue M, Moreno JA, Rosa JM, Roda JM, Hernández-García BJ, Egea J.

Br J Pharmacol. 2019 May 9. doi: 10.1111/bph.14703. [Epub ahead of print]

PMID:
31074003
2.

Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death.

Guerrero-Hue M, García-Caballero C, Palomino-Antolín A, Rubio-Navarro A, Vázquez-Carballo C, Herencia C, Martín-Sanchez D, Farré-Alins V, Egea J, Cannata P, Praga M, Ortiz A, Egido J, Sanz AB, Moreno JA.

FASEB J. 2019 Apr 29:fj201900077R. doi: 10.1096/fj.201900077R. [Epub ahead of print]

PMID:
31034781
3.

QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy.

Ramos E, Palomino-Antolín A, Bartolini M, Iriepa I, Moraleda I, Diez-Iriepa D, Samadi A, Cortina CV, Chioua M, Egea J, Romero A, Marco-Contelles J.

Molecules. 2019 Apr 17;24(8). pii: E1503. doi: 10.3390/molecules24081503.

4.

Serum Amyloid A1 as a Potential Intracranial and Extracranial Clinical Severity Biomarker in Traumatic Brain Injury.

Carabias CS, Castaño-León AM, Navarro B B, Panero I, Eiriz C, Gómez PA, Egea J, Lagares A.

J Intensive Care Med. 2019 Apr 8:885066619837913. doi: 10.1177/0885066619837913. [Epub ahead of print]

PMID:
30961443
5.

The emergence of melatonin in oncology: Focus on colorectal cancer.

Gil-Martín E, Egea J, Reiter RJ, Romero A.

Med Res Rev. 2019 Apr 4. doi: 10.1002/med.21582. [Epub ahead of print] Review.

PMID:
30950095
6.

From single drug targets to synergistic network pharmacology in ischemic stroke.

Casas AI, Hassan AA, Larsen SJ, Gomez-Rangel V, Elbatreek M, Kleikers PWM, Guney E, Egea J, López MG, Baumbach J, Schmidt HHHW.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7129-7136. doi: 10.1073/pnas.1820799116. Epub 2019 Mar 20.

7.

Tail or artefact? Illustration of the impact that uncertainty of the serial dilution and cell enumeration methods has on microbial inactivation.

Garre A, Egea JA, Esnoz A, Palop A, Fernandez PS.

Food Res Int. 2019 May;119:76-83. doi: 10.1016/j.foodres.2019.01.059. Epub 2019 Jan 24.

PMID:
30884713
8.

Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke.

Casas AI, Kleikers PW, Geuss E, Langhauser F, Adler T, Busch DH, Gailus-Durner V, de Angelis MH, Egea J, Lopez MG, Kleinschnitz C, Schmidt HH.

J Clin Invest. 2019 Mar 18;130:1772-1778. doi: 10.1172/JCI124283. eCollection 2019 Mar 18.

9.

Alectinib in the treatment of ALK-positive metastatic non-small cell lung cancer: clinical trial evidence and experience with a focus on brain metastases.

Tomasini P, Egea J, Souquet-Bressand M, Greillier L, Barlesi F.

Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619831906. doi: 10.1177/1753466619831906.

10.

Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model.

Llopiz D, Ruiz M, Villanueva L, Iglesias T, Silva L, Egea J, Lasarte JJ, Pivette P, Trochon-Joseph V, Vasseur B, Dixon G, Sangro B, Sarobe P.

Cancer Immunol Immunother. 2019 Mar;68(3):379-393. doi: 10.1007/s00262-018-2283-0. Epub 2018 Dec 13.

PMID:
30547218
11.

Improving the EFMs quality by augmenting their representativeness in LP methods.

Hidalgo JF, Egea JA, Guil F, García JM.

BMC Syst Biol. 2018 Nov 20;12(Suppl 5):101. doi: 10.1186/s12918-018-0619-1.

12.

proBDNF is modified by advanced glycation end products in Alzheimer's disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing.

Fleitas C, Piñol-Ripoll G, Marfull P, Rocandio D, Ferrer I, Rampon C, Egea J, Espinet C.

Mol Brain. 2018 Nov 14;11(1):68. doi: 10.1186/s13041-018-0411-6.

13.

Bioinactivation FE: A free web application for modelling isothermal and dynamic microbial inactivation.

Garre A, Clemente-Carazo M, Fernández PS, Lindqvist R, Egea JA.

Food Res Int. 2018 Oct;112:353-360. doi: 10.1016/j.foodres.2018.06.057. Epub 2018 Jun 25.

PMID:
30131146
14.

Relevance of the Induced Stress Resistance When Identifying the Critical Microorganism for Microbial Risk Assessment.

Garre A, Egea JA, Iguaz A, Palop A, Fernandez PS.

Front Microbiol. 2018 Jul 24;9:1663. doi: 10.3389/fmicb.2018.01663. eCollection 2018.

15.

Role of self-expanding stents in the treatment of intrathoracic dehiscence after Ivor Lewis esophagectomy.

Ruiz de Angulo D, Ortiz MÁ, Munitiz V, Martínez de Haro LF, Alberca F, Serrano A, Egea J, Parrilla P.

Cir Esp. 2018 Nov;96(9):555-559. doi: 10.1016/j.ciresp.2018.05.004. Epub 2018 Jun 20. English, Spanish.

PMID:
29934256
16.

Modulation of serine/threonine phosphatases by melatonin: therapeutic approaches in neurodegenerative diseases.

Arribas RL, Romero A, Egea J, de Los Ríos C.

Br J Pharmacol. 2018 Aug;175(16):3220-3229. doi: 10.1111/bph.14365. Epub 2018 Jun 19. Review.

PMID:
29781146
17.

Optimal characterization of thermal microbial inactivation simulating non-isothermal processes.

Garre A, González-Tejedor G, Peñalver-Soto JL, Fernández PS, Egea JA.

Food Res Int. 2018 May;107:267-274. doi: 10.1016/j.foodres.2018.02.040. Epub 2018 Feb 16. No abstract available.

PMID:
29580484
18.

Analysis of gene expression profiles of CR80, a neuroprotective 1,8-Naphthyridine.

Ramos E, Romero A, Egea J, Marco-Contelles J, Del Pino J, de Los Ríos C.

Future Med Chem. 2018 Jun 1;10(11):1289-1300. doi: 10.4155/fmc-2018-0004. Epub 2018 Mar 21.

PMID:
29560738
19.

Enhanced synaptic plasticity and spatial memory in female but not male FLRT2-haplodeficient mice.

Cicvaric A, Yang J, Bulat T, Zambon A, Dominguez-Rodriguez M, Kühn R, Sadowicz MG, Siwert A, Egea J, Pollak DD, Moeslinger T, Monje FJ.

Sci Rep. 2018 Feb 27;8(1):3703. doi: 10.1038/s41598-018-22030-4.

20.

Metabolomic Estimation of the Diagnosis and Onset Time of Permanent and Transient Cerebral Ischemia.

Cambray S, Portero-Otin M, Jové M, Torreguitart N, Colàs-Campàs L, Sanz A, Benabdelhak I, Yemisci M, Dalkara T, Dönmez-Demir B, Egea J, Purroy F.

Mol Neurobiol. 2018 Jul;55(7):6193-6200. doi: 10.1007/s12035-017-0827-5. Epub 2017 Dec 21.

PMID:
29270918
21.

Mathematical quantification of the induced stress resistance of microbial populations during non-isothermal stresses.

Garre A, Huertas JP, González-Tejedor GA, Fernández PS, Egea JA, Palop A, Esnoz A.

Int J Food Microbiol. 2018 Feb 2;266:133-141. doi: 10.1016/j.ijfoodmicro.2017.11.023. Epub 2017 Nov 27.

PMID:
29216553
22.

Podocytes are new cellular targets of haemoglobin-mediated renal damage.

Rubio-Navarro A, Sanchez-Niño MD, Guerrero-Hue M, García-Caballero C, Gutiérrez E, Yuste C, Sevillano Á, Praga M, Egea J, Román E, Cannata P, Ortega R, Cortegano I, de Andrés B, Gaspar ML, Cadenas S, Ortiz A, Egido J, Moreno JA.

J Pathol. 2018 Mar;244(3):296-310. doi: 10.1002/path.5011. Epub 2018 Jan 10.

PMID:
29205354
23.

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2018 Apr;14:694-696. doi: 10.1016/j.redox.2017.10.001. Epub 2017 Oct 26. No abstract available.

24.

NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.

Casas AI, Geuss E, Kleikers PWM, Mencl S, Herrmann AM, Buendia I, Egea J, Meuth SG, Lopez MG, Kleinschnitz C, Schmidt HHHW.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12315-12320. doi: 10.1073/pnas.1705034114. Epub 2017 Oct 31.

25.

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.

Bautista-Aguilera ÓM, Hagenow S, Palomino-Antolin A, Farré-Alins V, Ismaili L, Joffrin PL, Jimeno ML, Soukup O, Janočková J, Kalinowsky L, Proschak E, Iriepa I, Moraleda I, Schwed JS, Romero Martínez A, López-Muñoz F, Chioua M, Egea J, Ramsay RR, Marco-Contelles J, Stark H.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12765-12769. doi: 10.1002/anie.201706072. Epub 2017 Sep 1.

PMID:
28861918
26.

Four Years' Experience in the Diagnosis of Very Long-Chain Acyl-CoA Dehydrogenase Deficiency in Infants Detected in Three Spanish Newborn Screening Centers.

Merinero B, Alcaide P, Martín-Hernández E, Morais A, García-Silva MT, Quijada-Fraile P, Pedrón-Giner C, Dulin E, Yahyaoui R, Egea JM, Belanger-Quintana A, Blasco-Alonso J, Fernandez Ruano ML, Besga B, Ferrer-López I, Leal F, Ugarte M, Ruiz-Sala P, Pérez B, Pérez-Cerdá C.

JIMD Rep. 2018;39:63-74. doi: 10.1007/8904_2017_40. Epub 2017 Jul 29.

27.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2017 Oct;13:94-162. doi: 10.1016/j.redox.2017.05.007. Epub 2017 May 18. Review. Erratum in: Redox Biol. 2018 Apr;14 :694-696.

28.

Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia.

Hernansanz-Agustín P, Ramos E, Navarro E, Parada E, Sánchez-López N, Peláez-Aguado L, Cabrera-García JD, Tello D, Buendia I, Marina A, Egea J, López MG, Bogdanova A, Martínez-Ruiz A.

Redox Biol. 2017 Aug;12:1040-1051. doi: 10.1016/j.redox.2017.04.025. Epub 2017 Apr 21.

29.

Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration.

Ramos E, Egea J, de Los Ríos C, Marco-Contelles J, Romero A.

Future Med Chem. 2017 May;9(8):765-780. doi: 10.4155/fmc-2017-0014. Epub 2017 May 12. Review.

PMID:
28498717
30.

Targeting Nrf2 in Protection Against Renal Disease.

Guerrero-Hue M, Farre-Alins V, Palomino-Antolin A, Parada E, Rubio-Navarro A, Egido J, Egea J, Moreno JA.

Curr Med Chem. 2017;24(33):3583-3605. doi: 10.2174/0929867324666170511120814. Review.

PMID:
28494744
31.

Neuroprotective effects of E-PodoFavalin-15999 (Atremorine®).

Romero A, Parada E, González-Lafuente L, Farré-Alins V, Ramos E, Cacabelos R, Egea J.

CNS Neurosci Ther. 2017 May;23(5):450-452. doi: 10.1111/cns.12693. Epub 2017 Mar 30. No abstract available.

PMID:
28371323
32.

Bioinactivation: Software for modelling dynamic microbial inactivation.

Garre A, Fernández PS, Lindqvist R, Egea JA.

Food Res Int. 2017 Mar;93:66-74. doi: 10.1016/j.foodres.2017.01.012. Epub 2017 Jan 20.

PMID:
28290281
33.

Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.

Monjas L, Arce MP, León R, Egea J, Pérez C, Villarroya M, López MG, Gil C, Conde S, Rodríguez-Franco MI.

Eur J Med Chem. 2017 Apr 21;130:60-72. doi: 10.1016/j.ejmech.2017.02.034. Epub 2017 Feb 22.

PMID:
28242552
34.

Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS.

Budni J, Molz S, Dal-Cim T, Martín-de-Saavedra MD, Egea J, Lopéz MG, Tasca CI, Rodrigues ALS.

Mol Neurobiol. 2018 Feb;55(2):1580-1589. doi: 10.1007/s12035-017-0425-6. Epub 2017 Feb 10.

PMID:
28185129
35.

Parameter estimation in large-scale systems biology models: a parallel and self-adaptive cooperative strategy.

Penas DR, González P, Egea JA, Doallo R, Banga JR.

BMC Bioinformatics. 2017 Jan 21;18(1):52. doi: 10.1186/s12859-016-1452-4.

36.

Ischemic brain injury: New insights on the protective role of melatonin.

Ramos E, Patiño P, Reiter RJ, Gil-Martín E, Marco-Contelles J, Parada E, de Los Rios C, Romero A, Egea J.

Free Radic Biol Med. 2017 Mar;104:32-53. doi: 10.1016/j.freeradbiomed.2017.01.005. Epub 2017 Jan 6. Review.

PMID:
28065781
37.

Sensory Input-Dependent Changes in Glutamatergic Neurotransmission- Related Genes and Proteins in the Adult Rat Trigeminal Ganglion.

Fernández-Montoya J, Buendia I, Martin YB, Egea J, Negredo P, Avendaño C.

Front Mol Neurosci. 2016 Nov 28;9:132. eCollection 2016.

38.

Checklist for the crop weeds of Paraguay.

De Egea J, Mereles F, Peña-Chocarro MD, Céspedes G.

PhytoKeys. 2016 Oct 18;(73):13-92. eCollection 2016.

39.

The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators.

Benchekroun M, Romero A, Egea J, León R, Michalska P, Buendía I, Jimeno ML, Jun D, Janockova J, Sepsova V, Soukup O, Bautista-Aguilera OM, Refouvelet B, Ouari O, Marco-Contelles J, Ismaili L.

J Med Chem. 2016 Nov 10;59(21):9967-9973. Epub 2016 Oct 31.

PMID:
27736061
40.

ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels.

Rieger DK, Navarro E, Buendia I, Parada E, González-Lafuente L, Leon R, Costa AP, Heinrich IA, Nascimento KS, Cavada BS, Lopez MG, Egea J, Leal RB.

Neurochem Res. 2017 Feb;42(2):347-359. doi: 10.1007/s11064-016-2078-7. Epub 2016 Oct 17.

PMID:
27747481
41.

Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices.

Patiño P, Parada E, Farré-Alins V, Molz S, Cacabelos R, Marco-Contelles J, López MG, Tasca CI, Ramos E, Romero A, Egea J.

Neurotoxicology. 2016 Dec;57:61-68. doi: 10.1016/j.neuro.2016.09.002. Epub 2016 Sep 9.

PMID:
27620136
42.

Regulation by L channels of Ca(2+)-evoked secretory responses in ouabain-treated chromaffin cells.

De Pascual R, Colmena I, Ruiz-Pascual L, Baraibar AM, Egea J, Gandía L, García AG.

Pflugers Arch. 2016 Oct;468(10):1779-92. doi: 10.1007/s00424-016-1866-x. Epub 2016 Aug 24.

PMID:
27558258
43.

Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography.

Zha X, Lamba D, Zhang L, Lou Y, Xu C, Kang D, Chen L, Xu Y, Zhang L, De Simone A, Samez S, Pesaresi A, Stojan J, Lopez MG, Egea J, Andrisano V, Bartolini M.

J Med Chem. 2016 Jan 14;59(1):114-31. doi: 10.1021/acs.jmedchem.5b01119. Epub 2015 Dec 29.

PMID:
26632651
44.

Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases.

Buendia I, Michalska P, Navarro E, Gameiro I, Egea J, León R.

Pharmacol Ther. 2016 Jan;157:84-104. doi: 10.1016/j.pharmthera.2015.11.003. Epub 2015 Nov 23. Review.

PMID:
26617217
45.

Ion channels, guidance molecules, intracellular signaling and transcription factors regulating nervous and vascular system development.

Akita T, Kumada T, Yoshihara S, Egea J, Yamagishi S.

J Physiol Sci. 2016 Mar;66(2):175-88. doi: 10.1007/s12576-015-0416-1. Epub 2015 Oct 27. Review.

46.

New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection.

Buendia I, Navarro E, Michalska P, Gameiro I, Egea J, Abril S, López A, González-Lafuente L, López MG, León R.

Future Med Chem. 2015;7(15):1961-9. doi: 10.4155/fmc.15.99. Epub 2015 Oct 23.

PMID:
26496465
47.

CALHM1 and its polymorphism P86L differentially control Ca²⁺homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β.

Moreno-Ortega AJ, Buendia I, Mouhid L, Egea J, Lucea S, Ruiz-Nuño A, López MG, Cano-Abad MF.

Aging Cell. 2015 Dec;14(6):1094-102. doi: 10.1111/acel.12403. Epub 2015 Sep 29.

48.

Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection.

Egea J, Buendia I, Parada E, Navarro E, León R, Lopez MG.

Biochem Pharmacol. 2015 Oct 15;97(4):463-472. doi: 10.1016/j.bcp.2015.07.032. Epub 2015 Jul 29. Review.

PMID:
26232730
49.

Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction.

Navarro E, Buendia I, Parada E, León R, Jansen-Duerr P, Pircher H, Egea J, Lopez MG.

Biochem Pharmacol. 2015 Oct 15;97(4):473-481. doi: 10.1016/j.bcp.2015.07.022. Epub 2015 Jul 23.

PMID:
26212551
50.

Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related models.

Buendia I, Gómez-Rangel V, González-Lafuente L, Parada E, León R, Gameiro I, Michalska P, Laudon M, Egea J, López MG.

Neuropharmacology. 2015 Dec;99:187-95. doi: 10.1016/j.neuropharm.2015.07.014. Epub 2015 Jul 15.

PMID:
26188145

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