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Items: 1 to 50 of 182

1.

Commentary: Is there more than one way to skin a pulmonary artery aneurysm?

Egan TM, Ikonomidis J.

J Thorac Cardiovasc Surg. 2019 Sep 23. pii: S0022-5223(19)32022-7. doi: 10.1016/j.jtcvs.2019.09.033. [Epub ahead of print] No abstract available.

PMID:
31679705
2.

Ca2+ flux through splice variants of the ATP-gated ionotropic receptor P2X7 is regulated by its cytoplasmic N terminus.

Liang X, Samways DSK, Cox J, Egan TM.

J Biol Chem. 2019 Aug 16;294(33):12521-12533. doi: 10.1074/jbc.RA119.009666. Epub 2019 Jun 27.

PMID:
31248985
3.

Overcoming challenges of lung recovery from uDCDDs - Felicidades!

Egan TM, Requard JJ 3rd.

Am J Transplant. 2019 Aug;19(8):2391-2392. doi: 10.1111/ajt.15506. Epub 2019 Jul 9. No abstract available.

PMID:
31220408
4.

Restructuring or replacing? The untold story of the 2018 OPTN contract renewal.

Egan TM, Requard Iii JJ.

Am J Transplant. 2019 May;19(5):1592. doi: 10.1111/ajt.15348. Epub 2019 Apr 3. No abstract available.

PMID:
30859676
5.

ATP-Gated P2X7 Receptors Require Chloride Channels To Promote Inflammation in Human Macrophages.

Janks L, Sprague RS, Egan TM.

J Immunol. 2019 Feb 1;202(3):883-898. doi: 10.4049/jimmunol.1801101. Epub 2018 Dec 31.

PMID:
30598517
6.

On broader geographic sharing of donor lungs.

Egan TM.

J Heart Lung Transplant. 2019 Feb;38(2):127-129. doi: 10.1016/j.healun.2018.11.010. Epub 2018 Nov 30. No abstract available.

PMID:
30554798
7.

A central role for P2X7 receptors in human microglia.

Janks L, Sharma CVR, Egan TM.

J Neuroinflammation. 2018 Nov 21;15(1):325. doi: 10.1186/s12974-018-1353-8.

8.

How Should Lungs Be Allocated for Transplant?

Egan TM.

Semin Respir Crit Care Med. 2018 Apr;39(2):126-137. doi: 10.1055/s-0037-1620265. Epub 2018 Mar 26. Review.

PMID:
29579766
9.

From 6 years to 5 days for organ allocation policy change.

Egan TM.

J Heart Lung Transplant. 2018 May;37(5):675-677. doi: 10.1016/j.healun.2017.12.010. Epub 2017 Dec 20. No abstract available.

PMID:
29358011
10.

Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease.

Jin H, Han J, Resing D, Liu H, Yue X, Miller RL, Schoch KM, Miller TM, Perlmutter JS, Egan TM, Tu Z.

Eur J Pharmacol. 2018 Feb 5;820:8-17. doi: 10.1016/j.ejphar.2017.12.006. Epub 2017 Dec 7.

11.

P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease.

Sáez-Orellana F, Fuentes-Fuentes MC, Godoy PA, Silva-Grecchi T, Panes JD, Guzmán L, Yévenes GE, Gavilán J, Egan TM, Aguayo LG, Fuentealba J.

Neuropharmacology. 2018 Jan;128:366-378. doi: 10.1016/j.neuropharm.2017.10.027. Epub 2017 Oct 25.

12.

Cardiac Risk Score-Halfway There.

Egan TM.

Transplantation. 2017 Dec;101(12):e350. doi: 10.1097/TP.0000000000001938. No abstract available.

PMID:
28885492
13.

Beware Cold Agglutinins in Organ Donors! Ex Vivo Lung Perfusion From an Uncontrolled Donation After Circulatory-Determination-of-Death Donor With a Cold Agglutinin: A Case Report.

Venkataraman A, Blackwell JW, Funkhouser WK, Birchard KR, Beamer SE, Simmons WT, Randell SH, Egan TM.

Transplant Proc. 2017 Sep;49(7):1678-1681. doi: 10.1016/j.transproceed.2017.04.004.

14.

Imitation is the Sincerest Form of Flattery.

Egan TM.

Dtsch Arztebl Int. 2017 Aug 7;114(31-32):543. doi: 10.3238/arztebl.2017.0543a. No abstract available.

15.

Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part III: Mechanisms: A 2016 Consensus Group Statement of the International Society for Heart and Lung Transplantation.

Gelman AE, Fisher AJ, Huang HJ, Baz MA, Shaver CM, Egan TM, Mulligan MS.

J Heart Lung Transplant. 2017 Oct;36(10):1114-1120. doi: 10.1016/j.healun.2017.07.014. Epub 2017 Jul 24. Review. No abstract available.

16.

Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response.

Han J, Liu H, Liu C, Jin H, Perlmutter JS, Egan TM, Tu Z.

Nucl Med Commun. 2017 May;38(5):372-382. doi: 10.1097/MNM.0000000000000660.

17.

CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury.

Ulmasov B, Bruno J, Oshima K, Cheng YW, Holly SP, Parise LV, Egan TM, Edwards JC.

Physiol Rep. 2017 Mar;5(5). pii: e13169. doi: 10.14814/phy2.13169.

18.

HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.

Migita K, Ozaki T, Shimoyama S, Yamada J, Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S.

Mol Pharmacol. 2016 Aug;90(2):116-26. doi: 10.1124/mol.115.102988. Epub 2016 Jun 14.

PMID:
27301716
19.

Effect of the lung allocation score on lung transplantation in the United States.

Egan TM, Edwards LB.

J Heart Lung Transplant. 2016 Apr;35(4):433-9. doi: 10.1016/j.healun.2016.01.010. Epub 2016 Jan 15.

PMID:
26922274
20.

Lungs From the Controlled Donation After Circulatory Determination of Death Donor: Perspectives From the United States and Beyond.

Dark JH, Egan TM.

Am J Transplant. 2016 Apr;16(4):1047-8. doi: 10.1111/ajt.13600. Epub 2016 Feb 4. No abstract available.

21.

Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3.

Li C, Ma W, Yin S, Liang X, Shu X, Pei D, Egan TM, Huang J, Pan A, Li Z.

Traffic. 2016 May;17(5):500-14. doi: 10.1111/tra.12379. Epub 2016 Feb 23.

22.

Lung Transplant From an Uncontrolled Donation After Circulatory Determination of Death Donor: Moving to Other Countries.

Egan TM.

Am J Transplant. 2016 Apr;16(4):1051-2. doi: 10.1111/ajt.13658. Epub 2016 Feb 17. No abstract available.

23.

Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.

Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Koninck Y, Tosh DK, Jacobson KA, Salvemini D.

J Neurosci. 2015 Apr 15;35(15):6057-67. doi: 10.1523/JNEUROSCI.4495-14.2015. Erratum in: J Neurosci. 2015 Jun 10;35(23):8971.

24.

Uncontrolled Donation After Circulatory Determination of Death Donors (uDCDDs) as a Source of Lungs for Transplant.

Egan TM, Requard JJ 3rd.

Am J Transplant. 2015 Aug;15(8):2031-6. doi: 10.1111/ajt.13246. Epub 2015 Apr 14.

25.

Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors.

Liang X, Samways DS, Wolf K, Bowles EA, Richards JP, Bruno J, Dutertre S, DiPaolo RJ, Egan TM.

J Biol Chem. 2015 Mar 20;290(12):7930-42. doi: 10.1074/jbc.M114.627810. Epub 2015 Feb 2.

26.

Emergency medical services knowledge and attitudes about non-heart-beating donors: effect of an educational intervention.

Burker EJ, Fingerhut D, Ebneter D, Giza M, Espey Weber R, Noone PG, Egan TM.

J Heart Lung Transplant. 2015 Feb;34(2):204-12. doi: 10.1016/j.healun.2014.09.020. Epub 2014 Sep 28.

27.

Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin.

Xu J, Chai H, Ehinger K, Egan TM, Srinivasan R, Frick M, Khakh BS.

J Gen Physiol. 2014 Jul;144(1):81-104. doi: 10.1085/jgp.201411169. Epub 2014 Jun 16.

28.

The lung allocation score goes global.

Egan TM.

Am J Transplant. 2014 Jun;14(6):1234-5. No abstract available.

29.

A little bit of leak goes a long way.

Egan TM.

J Heart Lung Transplant. 2014 Jul;33(7):769. doi: 10.1016/j.healun.2014.04.008. Epub 2014 Apr 21. No abstract available.

PMID:
24815796
30.

Principles and properties of ion flow in P2X receptors.

Samways DS, Li Z, Egan TM.

Front Cell Neurosci. 2014 Feb 5;8:6. doi: 10.3389/fncel.2014.00006. eCollection 2014. Review.

31.

Rationing lung transplants.

Egan TM, Sweet SC.

N Engl J Med. 2013 Nov 21;369(21):2064-5. doi: 10.1056/NEJMc1311946. No abstract available.

PMID:
24256395
32.

Effect of a vascular endothelial cadherin antagonist in a rat lung transplant model.

Tian Z, Dong B, Blackwell JW, Stewart PW, Egan TM.

Ann Thorac Surg. 2013 Mar;95(3):1028-33. doi: 10.1016/j.athoracsur.2012.11.023. Epub 2013 Jan 17.

PMID:
23333062
33.

Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors.

Dong B, Stewart PW, Egan TM.

J Thorac Cardiovasc Surg. 2013 Aug;146(2):429-36.e1. doi: 10.1016/j.jtcvs.2012.11.005. Epub 2012 Dec 20.

34.

Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals.

Samways DS, Khakh BS, Egan TM.

J Biol Chem. 2012 Mar 2;287(10):7594-602. doi: 10.1074/jbc.M111.322461. Epub 2012 Jan 4.

35.

Calcium-dependent decrease in the single-channel conductance of TRPV1.

Samways DS, Egan TM.

Pflugers Arch. 2011 Nov;462(5):681-91. doi: 10.1007/s00424-011-1013-7. Epub 2011 Sep 3.

36.

Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors).

Samways DS, Khakh BS, Dutertre S, Egan TM.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13800-5. doi: 10.1073/pnas.1017550108. Epub 2011 Aug 1.

37.

Simulation experience enhances medical students' interest in cardiothoracic surgery.

Tesche LJ, Feins RH, Dedmon MM, Newton KN, Egan TM, Haithcock BE, Veeramachaneni NK, Bowdish ME.

Ann Thorac Surg. 2010 Dec;90(6):1967-73; discussion 1973-4. doi: 10.1016/j.athoracsur.2010.06.117.

PMID:
21095347
38.

Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes.

Sridharan M, Adderley SP, Bowles EA, Egan TM, Stephenson AH, Ellsworth ML, Sprague RS.

Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1146-52. doi: 10.1152/ajpheart.00301.2010. Epub 2010 Jul 9.

39.

Depressive symptoms and mortality in lung transplant.

Evon DM, Burker EJ, Galanko JA, Dedert E, Egan TM.

Clin Transplant. 2010 Sep-Oct;24(5):E201-6. doi: 10.1111/j.1399-0012.2010.01236.x.

PMID:
20438580
40.

P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin.

Toulme E, Garcia A, Samways D, Egan TM, Carson MJ, Khakh BS.

J Gen Physiol. 2010 Apr;135(4):333-53. doi: 10.1085/jgp.200910336. Epub 2010 Mar 15.

41.

Nitric oxide ventilation of rat lungs from non-heart-beating donors improves posttransplant function.

Dong BM, Abano JB, Egan TM.

Am J Transplant. 2009 Dec;9(12):2707-15. doi: 10.1111/j.1600-6143.2009.02840.x. Epub 2009 Oct 21.

42.

In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation.

Casiraghi M, Tatreau JR, Abano JB, Blackwell JW, Watson L, Burridge K, Randell SH, Egan TM.

J Thorac Cardiovasc Surg. 2009 Sep;138(3):760-7. doi: 10.1016/j.jtcvs.2009.05.037.

43.

Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema.

Zanotti G, Casiraghi M, Abano JB, Tatreau JR, Sevala M, Berlin H, Smyth S, Funkhouser WK, Burridge K, Randell SH, Egan TM.

Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L52-63. doi: 10.1152/ajplung.90406.2008. Epub 2009 Apr 17.

44.

The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages.

Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H.

Eur J Immunol. 2009 Mar;39(3):820-5. doi: 10.1002/eji.200838683.

45.

Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry.

Samways DS, Harkins AB, Egan TM.

Cell Calcium. 2009 Apr;45(4):319-25. doi: 10.1016/j.ceca.2008.12.002. Epub 2009 Jan 29.

46.

Tunable calcium current through TRPV1 receptor channels.

Samways DS, Khakh BS, Egan TM.

J Biol Chem. 2008 Nov 14;283(46):31274-8. doi: 10.1074/jbc.C800131200. Epub 2008 Sep 5.

47.

Solid benefit of lung transplantation for some children with cystic fibrosis.

Egan TM.

Pediatr Transplant. 2008 Mar;12(2):125-8. doi: 10.1111/j.1399-3046.2008.00933.x. No abstract available.

PMID:
18307659
48.

On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor.

Samways DS, Migita K, Li Z, Egan TM.

J Biol Chem. 2008 Feb 22;283(8):5110-7. Epub 2007 Nov 29.

49.

Plus ça change...

Egan TM, McLeod R.

J Am Coll Surg. 2007 Oct;205(4):e5. No abstract available.

PMID:
17903720
50.

Functional expression of mammalian receptors and membrane channels in different cells.

Eifler N, Duckely M, Sumanovski LT, Egan TM, Oksche A, Konopka JB, Lüthi A, Engel A, Werten PJ.

J Struct Biol. 2007 Aug;159(2):179-93. Epub 2007 Feb 3.

PMID:
17368047

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