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Items: 1 to 50 of 225

1.

Insulin is produced in choroid plexus and its release is regulated by serotonergic signaling.

Mazucanti CH, Liu QR, Lang D, Huang N, O'Connell JF, Camandola S, Egan JM.

JCI Insight. 2019 Oct 24. pii: 131682. doi: 10.1172/jci.insight.131682. [Epub ahead of print]

2.

A Pilot Study of Exenatide Actions in Alzheimer's Disease.

Mullins RJ, Mustapic M, Chia CW, Carlson O, Gulyani S, Tran J, Li Y, Mattson MP, Resnick S, Egan JM, Greig NH, Kapogiannis D.

Curr Alzheimer Res. 2019;16(8):741-752. doi: 10.2174/1567205016666190913155950.

PMID:
31518224
3.

Linoleic acid in diets of mice increases total endocannabinoid levels in bowel and liver: modification by dietary glucose.

Ghosh S, O'Connell JF, Carlson OD, González-Mariscal I, Kim Y, Moaddel R, Ghosh P, Egan JM.

Obes Sci Pract. 2019 Jul 16;5(4):383-394. doi: 10.1002/osp4.344. eCollection 2019 Aug.

4.

Effect of Rifaximin Treatment on Endotoxemia and Insulin Sensitivity in Humans.

Finlin BS, Zhu B, Boyechko T, Westgate PM, Chia CW, Egan JM, Kern PA.

J Endocr Soc. 2019 Jun 26;3(9):1641-1651. doi: 10.1210/js.2019-00148. eCollection 2019 Sep 1.

5.

Incretins in obesity and diabetes.

Chia CW, Egan JM.

Ann N Y Acad Sci. 2019 Aug 7. doi: 10.1111/nyas.14211. [Epub ahead of print] Review.

PMID:
31392745
6.

Dietary curcumin enhances insulin clearance in diet-induced obese mice via regulation of hepatic PI3K-AKT axis and IDE, and preservation of islet integrity.

Kim Y, Rouse M, González-Mariscal I, Egan JM, O'Connell JF.

Nutr Metab (Lond). 2019 Jul 25;16:48. doi: 10.1186/s12986-019-0377-0. eCollection 2019.

7.

Correction to: Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease.

Hishimoto A, Pletnikova O, Lang DL, Troncoso JC, Egan JM, Liu QR.

Alzheimers Res Ther. 2019 May 7;11(1):39. doi: 10.1186/s13195-019-0493-0.

8.

Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease.

Hishimoto A, Pletnikova O, Lang DL, Troncoso JC, Egan JM, Liu QR.

Alzheimers Res Ther. 2019 Mar 21;11(1):28. doi: 10.1186/s13195-019-0475-2. Erratum in: Alzheimers Res Ther. 2019 May 7;11(1):39.

9.

Electrophysiological properties of rat subfornical organ neurons expressing calbindin D28K.

Huang S, Egan JM, Fry WM.

Neuroscience. 2019 Apr 15;404:459-469. doi: 10.1016/j.neuroscience.2019.02.017. Epub 2019 Feb 21.

PMID:
30797023
10.

Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism.

González-Mariscal I, Montoro RA, O'Connell JF, Kim Y, Gonzalez-Freire M, Liu QR, Alfaras I, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Hardivillé S, Ghosh P, Egan JM.

FASEB J. 2019 May;33(5):5850-5863. doi: 10.1096/fj.201801145R. Epub 2019 Feb 6.

PMID:
30726112
11.

IGFBP-2 and aging: a 20-year longitudinal study on IGFBP-2, IGF-I, BMI, insulin sensitivity and mortality in an aging population.

van den Beld AW, Carlson OD, Doyle ME, Rizopoulos D, Ferrucci L, van der Lely AJ, Egan JM.

Eur J Endocrinol. 2019 Feb 1;180(2):109-116. doi: 10.1530/EJE-18-0422.

12.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):248-249. doi: 10.1039/c8np90041h. Epub 2018 Nov 23.

13.

Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.

Semba RD, Zhang P, Zhu M, Fabbri E, Gonzalez-Freire M, Carlson OD, Moaddel R, Tanaka T, Egan JM, Ferrucci L.

J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):129-136. doi: 10.1093/gerona/gly255.

PMID:
30380014
14.

Age-Related Changes in Glucose Metabolism, Hyperglycemia, and Cardiovascular Risk.

Chia CW, Egan JM, Ferrucci L.

Circ Res. 2018 Sep 14;123(7):886-904. doi: 10.1161/CIRCRESAHA.118.312806. Review.

15.

Identification of novel mouse and rat CB1R isoforms and in silico modeling of human CB1R for peripheral cannabinoid therapeutics.

Liu QR, Huang NS, Qu H, O'Connell JF, Gonzalez-Mariscal I, Santa-Cruz-Calvo S, Doyle ME, Xi ZX, Wang Y, Onaivi ES, Egan JM.

Acta Pharmacol Sin. 2019 Mar;40(3):387-397. doi: 10.1038/s41401-018-0152-1. Epub 2018 Sep 10.

PMID:
30202012
16.

Oral glucose load and mixed meal feeding lowers testosterone levels in healthy eugonadal men.

Gagliano-Jucá T, Li Z, Pencina KM, Beleva YM, Carlson OD, Egan JM, Basaria S.

Endocrine. 2019 Jan;63(1):149-156. doi: 10.1007/s12020-018-1741-y. Epub 2018 Sep 6.

17.

Insulin Is Transcribed and Translated in Mammalian Taste Bud Cells.

Doyle ME, Fiori JL, Gonzalez Mariscal I, Liu QR, Goodstein E, Yang H, Shin YK, Santa-Cruz Calvo S, Indig FE, Egan JM.

Endocrinology. 2018 Sep 1;159(9):3331-3339. doi: 10.1210/en.2018-00534.

18.

The physiology of endocrine systems with ageing.

van den Beld AW, Kaufman JM, Zillikens MC, Lamberts SWJ, Egan JM, van der Lely AJ.

Lancet Diabetes Endocrinol. 2018 Aug;6(8):647-658. doi: 10.1016/S2213-8587(18)30026-3. Epub 2018 Jul 17. Review.

19.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Review. Erratum in: Nat Prod Rep. 2018 Nov 23;:.

20.

Lack of current observed in HEK293 cells expressing NALCN channels.

Egan JM, Peterson CA, Fry WM.

Biochim Open. 2018 Feb 5;6:24-28. doi: 10.1016/j.biopen.2018.01.001. eCollection 2018 Jun.

21.

Regular low-calorie sweetener consumption is associated with increased secretion of glucose-dependent insulinotropic polypeptide.

Chia CW, Shardell M, Gravenstein KS, Carlson OD, Simonsick EM, Ferrucci L, Egan JM.

Diabetes Obes Metab. 2018 Sep;20(9):2282-2285. doi: 10.1111/dom.13328. Epub 2018 May 9.

22.

Endocannabinoids in the Islets of Langerhans: the ugly, the bad, and the good facts.

González-Mariscal I, Egan JM.

Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E174-E179. doi: 10.1152/ajpendo.00338.2017. Epub 2018 Apr 6. Review.

23.

Measurement of fat fraction in the human thymus by localized NMR and three-point Dixon MRI techniques.

Fishbein KW, Makrogiannis SK, Lukas VA, Okine M, Ramachandran R, Ferrucci L, Egan JM, Chia CW, Spencer RG.

Magn Reson Imaging. 2018 Jul;50:110-118. doi: 10.1016/j.mri.2018.03.016. Epub 2018 Mar 29.

24.

Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets.

González-Mariscal I, Montoro RA, Doyle ME, Liu QR, Rouse M, O'Connell JF, Santa-Cruz Calvo S, Krzysik-Walker SM, Ghosh S, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Chia CW, Ghosh P, Egan JM.

Diabetologia. 2018 Jun;61(6):1470-1483. doi: 10.1007/s00125-018-4576-4. Epub 2018 Mar 1.

25.

Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells.

Shin H, Han JH, Yoon J, Sim HJ, Park TJ, Yang S, Lee EK, Kulkarni RN, Egan JM, Kim W.

J Cell Mol Med. 2018 Apr;22(4):2337-2345. doi: 10.1111/jcmm.13523. Epub 2018 Feb 12.

26.

Elevated Markers of Inflammation Are Associated With Longitudinal Changes in Brain Function in Older Adults.

Warren KN, Beason-Held LL, Carlson O, Egan JM, An Y, Doshi J, Davatzikos C, Ferrucci L, Resnick SM.

J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):770-778. doi: 10.1093/gerona/glx199.

27.

Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference.

Liu QR, Canseco-Alba A, Zhang HY, Tagliaferro P, Chung M, Dennis E, Sanabria B, Schanz N, Escosteguy-Neto JC, Ishiguro H, Lin Z, Sgro S, Leonard CM, Santos-Junior JG, Gardner EL, Egan JM, Lee JW, Xi ZX, Onaivi ES.

Sci Rep. 2017 Dec 12;7(1):17410. doi: 10.1038/s41598-017-17796-y.

28.

Evidence for brain glucose dysregulation in Alzheimer's disease.

An Y, Varma VR, Varma S, Casanova R, Dammer E, Pletnikova O, Chia CW, Egan JM, Ferrucci L, Troncoso J, Levey AI, Lah J, Seyfried NT, Legido-Quigley C, O'Brien R, Thambisetty M.

Alzheimers Dement. 2018 Mar;14(3):318-329. doi: 10.1016/j.jalz.2017.09.011. Epub 2017 Oct 19.

29.

CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ9-Tetrahydrocannabinol (Δ9-THC)-Induced Aversive Effects in Mice.

Han X, He Y, Bi GH, Zhang HY, Song R, Liu QR, Egan JM, Gardner EL, Li J, Xi ZX.

Sci Rep. 2017 Sep 26;7(1):12315. doi: 10.1038/s41598-017-12399-z.

30.

Incretin secretion in humans is under the influence of cannabinoid receptors.

Chia CW, Carlson OD, Liu DD, González-Mariscal I, Santa-Cruz Calvo S, Egan JM.

Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E359-E366. doi: 10.1152/ajpendo.00080.2017. Epub 2017 Jun 27.

31.

Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis).

Egan JM, Kaur A, Raja HA, Kellogg JJ, Oberlies NH, Cech NB.

Phytochem Lett. 2016 Sep;17:219-225. doi: 10.1016/j.phytol.2016.07.031. Epub 2016 Aug 6.

32.

A gaze independent hybrid-BCI based on visual spatial attention.

Egan JM, Loughnane GM, Fletcher H, Meade E, Lalor EC.

J Neural Eng. 2017 Aug;14(4):046006. doi: 10.1088/1741-2552/aa6bb2.

PMID:
28513478
33.

Effects of transdermal testosterone gel or an aromatase inhibitor on serum concentration and pulsatility of growth hormone in older men with age-related low testosterone.

Dias JP, Veldhuis JD, Carlson O, Shardell M, Chia CW, Melvin D, Egan JM, Basaria S.

Metabolism. 2017 Apr;69:143-147. doi: 10.1016/j.metabol.2017.01.025. Epub 2017 Jan 19.

34.

Targeted proteomics of cannabinoid receptor CB1 and the CB1b isoform.

Ghosh S, González-Mariscal I, Egan JM, Moaddel R.

J Pharm Biomed Anal. 2017 Sep 10;144:154-158. doi: 10.1016/j.jpba.2016.11.003. Epub 2016 Nov 11.

35.

Chronic Low-Calorie Sweetener Use and Risk of Abdominal Obesity among Older Adults: A Cohort Study.

Chia CW, Shardell M, Tanaka T, Liu DD, Gravenstein KS, Simonsick EM, Egan JM, Ferrucci L.

PLoS One. 2016 Nov 23;11(11):e0167241. doi: 10.1371/journal.pone.0167241. eCollection 2016.

36.

Testosterone vs. aromatase inhibitor in older men with low testosterone: effects on cardiometabolic parameters.

Dias JP, Shardell MD, Carlson OD, Melvin D, Caturegli G, Ferrucci L, Chia CW, Egan JM, Basaria S.

Andrology. 2017 Jan;5(1):31-40. doi: 10.1111/andr.12284. Epub 2016 Oct 28.

37.

Insulin Resistance Is Associated With Reduced Mitochondrial Oxidative Capacity Measured by 31P-Magnetic Resonance Spectroscopy in Participants Without Diabetes From the Baltimore Longitudinal Study of Aging.

Fabbri E, Chia CW, Spencer RG, Fishbein KW, Reiter DA, Cameron D, Zane AC, Moore ZA, Gonzalez-Freire M, Zoli M, Studenski SA, Kalyani RR, Egan JM, Ferrucci L.

Diabetes. 2017 Jan;66(1):170-176. doi: 10.2337/db16-0754. Epub 2016 Oct 13.

38.

Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism.

González-Mariscal I, Krzysik-Walker SM, Doyle ME, Liu QR, Cimbro R, Santa-Cruz Calvo S, Ghosh S, Cieśla Ł, Moaddel R, Carlson OD, Witek RP, O'Connell JF, Egan JM.

Sci Rep. 2016 Sep 19;6:33302. doi: 10.1038/srep33302.

39.

Association of abdominal fat with serum amylase in an older cohort: The Baltimore Longitudinal Study of Aging.

Dias JP, Schrack JA, Shardell MD, Egan JM, Studenski S.

Diabetes Res Clin Pract. 2016 Jun;116:212-7. doi: 10.1016/j.diabres.2016.04.015. Epub 2016 Apr 26.

40.

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.

Mitchell SJ, Madrigal-Matute J, Scheibye-Knudsen M, Fang E, Aon M, González-Reyes JA, Cortassa S, Kaushik S, Gonzalez-Freire M, Patel B, Wahl D, Ali A, Calvo-Rubio M, Burón MI, Guiterrez V, Ward TM, Palacios HH, Cai H, Frederick DW, Hine C, Broeskamp F, Habering L, Dawson J, Beasley TM, Wan J, Ikeno Y, Hubbard G, Becker KG, Zhang Y, Bohr VA, Longo DL, Navas P, Ferrucci L, Sinclair DA, Cohen P, Egan JM, Mitchell JR, Baur JA, Allison DB, Anson RM, Villalba JM, Madeo F, Cuervo AM, Pearson KJ, Ingram DK, Bernier M, de Cabo R.

Cell Metab. 2016 Jun 14;23(6):1093-1112. doi: 10.1016/j.cmet.2016.05.027.

41.

Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells.

Kim J, Lee KJ, Kim JS, Rho JG, Shin JJ, Song WK, Lee EK, Egan JM, Kim W.

PLoS One. 2016 Mar 11;11(3):e0150981. doi: 10.1371/journal.pone.0150981. eCollection 2016.

42.

Effects of Transdermal Testosterone Gel or an Aromatase Inhibitor on Prostate Volume in Older Men.

Dias JP, Melvin D, Shardell M, Ferrucci L, Chia CW, Gharib M, Egan JM, Basaria S.

J Clin Endocrinol Metab. 2016 Apr;101(4):1865-71. doi: 10.1210/jc.2016-1111. Epub 2016 Mar 7.

43.

Bioavailable Testosterone Linearly Declines Over A Wide Age Spectrum in Men and Women From The Baltimore Longitudinal Study of Aging.

Fabbri E, An Y, Gonzalez-Freire M, Zoli M, Maggio M, Studenski SA, Egan JM, Chia CW, Ferrucci L.

J Gerontol A Biol Sci Med Sci. 2016 Sep;71(9):1202-9. doi: 10.1093/gerona/glw021. Epub 2016 Feb 27.

44.

Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds.

Kellogg JJ, Todd DA, Egan JM, Raja HA, Oberlies NH, Kvalheim OM, Cech NB.

J Nat Prod. 2016 Feb 26;79(2):376-86. doi: 10.1021/acs.jnatprod.5b01014. Epub 2016 Feb 3.

45.

Free Thyroxine and Functional Mobility, Fitness, and Fatigue in Euthyroid Older Men and Women in the Baltimore Longitudinal Study of Aging.

Simonsick EM, Chia CW, Mammen JS, Egan JM, Ferrucci L.

J Gerontol A Biol Sci Med Sci. 2016 Jul;71(7):961-7. doi: 10.1093/gerona/glv226. Epub 2016 Jan 20.

46.

Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice.

González-Mariscal I, Krzysik-Walker SM, Kim W, Rouse M, Egan JM.

Mol Cell Endocrinol. 2016 Mar 5;423:1-10. doi: 10.1016/j.mce.2015.12.015. Epub 2015 Dec 25.

47.

Effects of aromatase inhibition vs. testosterone in older men with low testosterone: randomized-controlled trial.

Dias JP, Melvin D, Simonsick EM, Carlson O, Shardell MD, Ferrucci L, Chia CW, Basaria S, Egan JM.

Andrology. 2016 Jan;4(1):33-40. doi: 10.1111/andr.12126. Epub 2015 Nov 20.

48.

Targeting Stem Cells in Chronic Myeloid Leukemia with a PPAR-γ Agonist.

Egan JM.

N Engl J Med. 2015 Nov 12;373(20):1973-5. doi: 10.1056/NEJMcibr1511276.

PMID:
26559576
49.

Does GLP-1 suppress its own basal secretion?

Elahi D, Ruff DA, Carlson OD, Meneilly GS, Habener JF, Egan JM.

Endocr Res. 2016;41(1):16-20. doi: 10.3109/07435800.2015.1038353. Epub 2015 Jul 17.

50.

A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition.

Brown AR, Ettefagh KA, Todd D, Cole PS, Egan JM, Foil DH, Graf TN, Schindler BD, Kaatz GW, Cech NB.

PLoS One. 2015 May 11;10(5):e0124814. doi: 10.1371/journal.pone.0124814. eCollection 2015.

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