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Items: 1 to 50 of 177

1.

Short communication: Milk fat payment affects the relative profitability of Jersey and Holstein-Friesian cows at optimal comparative stocking rate.

Edwards JP, Spaans OK, Neal M, Macdonald KA.

J Dairy Sci. 2019 Oct;102(10):9463-9467. doi: 10.3168/jds.2018-16152. Epub 2019 Aug 1.

PMID:
31378486
2.

Tear Lactoferrin and Lysozyme as Clinically Relevant Biomarkers of Mucosal Immune Competence.

Hanstock HG, Edwards JP, Walsh NP.

Front Immunol. 2019 May 31;10:1178. doi: 10.3389/fimmu.2019.01178. eCollection 2019.

3.

Electrochemical CO2 Reduction into Chemical Feedstocks: From Mechanistic Electrocatalysis Models to System Design.

Kibria MG, Edwards JP, Gabardo CM, Dinh CT, Seifitokaldani A, Sinton D, Sargent EH.

Adv Mater. 2019 Aug;31(31):e1807166. doi: 10.1002/adma.201807166. Epub 2019 May 16. Review.

PMID:
31095806
4.

Chimeric Antigen Receptors Incorporating D Domains Targeting CD123 Direct Potent Mono- and Bi-specific Antitumor Activity of T Cells.

Qin H, Edwards JP, Zaritskaya L, Gupta A, Mu CJ, Fry TJ, Hilbert DM, LaFleur DW.

Mol Ther. 2019 Jul 3;27(7):1262-1274. doi: 10.1016/j.ymthe.2019.04.010. Epub 2019 Apr 17.

PMID:
31043341
5.

Discovery, Optimization, and Evaluation of Potent and Highly Selective PI3Kγ-PI3Kδ Dual Inhibitors.

Jia H, Dai G, Su W, Xiao K, Weng J, Zhang Z, Wang Q, Yuan T, Shi F, Zhang Z, Chen W, Sai Y, Wang J, Li X, Cai Y, Yu J, Ren P, Venable J, Rao T, Edwards JP, Bembenek SD.

J Med Chem. 2019 May 23;62(10):4936-4948. doi: 10.1021/acs.jmedchem.8b02014. Epub 2019 May 8.

PMID:
31033293
6.

3-Substituted Quinolines as RORγt Inverse Agonists.

Tanis VM, Venkatesan H, Cummings MD, Albers M, Kent Barbay J, Herman K, Kummer DA, Milligan C, Nelen MI, Nishimura R, Schlueter T, Scott B, Spurlino J, Wolin R, Woods C, Xue X, Edwards JP, Fourie AM, Leonard K.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1463-1470. doi: 10.1016/j.bmcl.2019.04.021. Epub 2019 Apr 12.

PMID:
31010722
7.

Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry.

Damm-Ganamet KL, Arora N, Becart S, Edwards JP, Lebsack AD, McAllister HM, Nelen MI, Rao NL, Westover L, Wiener JJM, Mirzadegan T.

J Chem Inf Model. 2019 May 28;59(5):2046-2062. doi: 10.1021/acs.jcim.8b00941. Epub 2019 Mar 13.

PMID:
30817167
8.

Copper adparticle enabled selective electrosynthesis of n-propanol.

Li J, Che F, Pang Y, Zou C, Howe JY, Burdyny T, Edwards JP, Wang Y, Li F, Wang Z, De Luna P, Dinh CT, Zhuang TT, Saidaminov MI, Cheng S, Wu T, Finfrock YZ, Ma L, Hsieh SH, Liu YS, Botton GA, Pong WF, Du X, Guo J, Sham TK, Sargent EH, Sinton D.

Nat Commun. 2018 Nov 5;9(1):4614. doi: 10.1038/s41467-018-07032-0.

9.

Minisci-Photoredox-Mediated α-Heteroarylation of N-Protected Secondary Amines: Remarkable Selectivity of Azetidines.

Bosset C, Beucher H, Bretel G, Pasquier E, Queguiner L, Henry C, Vos A, Edwards JP, Meerpoel L, Berthelot D.

Org Lett. 2018 Oct 5;20(19):6003-6006. doi: 10.1021/acs.orglett.8b00991. Epub 2018 Sep 25.

PMID:
30252482
10.

Synchronous colorectal liver metastases: a national survey of surgeon opinions on simultaneous resection and multidisciplinary cooperation.

Howard C, Clements TW, Edwards JP, MacLean AR, Buie WD, Dixon E, Grondin SC, Gomes A, McColl M, Cleary SP, Jayaraman S, Daigle R, Ball CG.

Hepatobiliary Surg Nutr. 2018 Aug;7(4):242-250. doi: 10.21037/hbsn.2017.12.01.

11.

CO2 electroreduction to ethylene via hydroxide-mediated copper catalysis at an abrupt interface.

Dinh CT, Burdyny T, Kibria MG, Seifitokaldani A, Gabardo CM, García de Arquer FP, Kiani A, Edwards JP, De Luna P, Bushuyev OS, Zou C, Quintero-Bermudez R, Pang Y, Sinton D, Sargent EH.

Science. 2018 May 18;360(6390):783-787. doi: 10.1126/science.aas9100.

PMID:
29773749
12.

Integral transforms of the quantum mechanical path integral: Hit function and path-averaged potential.

Edwards JP, Gerber U, Schubert C, Trejo MA, Weber A.

Phys Rev E. 2018 Apr;97(4-1):042114. doi: 10.1103/PhysRevE.97.042114.

PMID:
29758645
13.

Identification and biological evaluation of thiazole-based inverse agonists of RORγt.

Gege C, Cummings MD, Albers M, Kinzel O, Kleymann G, Schlüter T, Steeneck C, Nelen MI, Milligan C, Spurlino J, Xue X, Leonard K, Edwards JP, Fourie A, Goldberg SD, Hoffmann T.

Bioorg Med Chem Lett. 2018 May 15;28(9):1446-1455. doi: 10.1016/j.bmcl.2018.03.093. Epub 2018 Apr 3.

PMID:
29631962
14.

Hydronium-Induced Switching between CO2 Electroreduction Pathways.

Seifitokaldani A, Gabardo CM, Burdyny T, Dinh CT, Edwards JP, Kibria MG, Bushuyev OS, Kelley SO, Sinton D, Sargent EH.

J Am Chem Soc. 2018 Mar 21;140(11):3833-3837. doi: 10.1021/jacs.7b13542. Epub 2018 Mar 9.

PMID:
29504748
15.

Anxiety and perceived psychological stress play an important role in the immune response after exercise.

Edwards JP, Walsh NP, Diment PC, Roberts R.

Exerc Immunol Rev. 2018;24:26-34.

16.

High heart rate reactors display greater decreases in tear SIgA concentration following a novel acute stressor.

Hanstock HG, Edwards JP, Roberts R, Walsh NP.

Biol Psychol. 2018 Mar;133:85-88. doi: 10.1016/j.biopsycho.2018.02.002. Epub 2018 Feb 7.

PMID:
29427602
17.

Efficacy of a Dual-ring Wound Protector for Prevention of Surgical Site Infections After Pancreaticoduodenectomy in Patients With Intrabiliary Stents: A Randomized Clinical Trial.

Bressan AK, Aubin JM, Martel G, Dixon E, Bathe OF, Sutherland FR, Balaa F, Mimeault R, Edwards JP, Grondin SC, Isherwood S, Lillemoe KD, Saeed S, Ball CG.

Ann Surg. 2018 Jul;268(1):35-40. doi: 10.1097/SLA.0000000000002614.

PMID:
29240005
18.

6-Substituted quinolines as RORγt inverse agonists.

Barbay JK, Cummings MD, Abad M, Castro G, Kreutter KD, Kummer DA, Maharoof U, Milligan C, Nishimura R, Pierce J, Schalk-Hihi C, Spurlino J, Tanis VM, Urbanski M, Venkatesan H, Wang A, Woods C, Wolin R, Xue X, Edwards JP, Fourie AM, Leonard K.

Bioorg Med Chem Lett. 2017 Dec 1;27(23):5277-5283. doi: 10.1016/j.bmcl.2017.10.027. Epub 2017 Oct 16.

PMID:
29079472
19.

Small-Molecule Targets in Immuno-Oncology.

Dhanak D, Edwards JP, Nguyen A, Tummino PJ.

Cell Chem Biol. 2017 Sep 21;24(9):1148-1160. doi: 10.1016/j.chembiol.2017.08.019. Review.

20.

Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt.

Kummer DA, Cummings MD, Abad M, Barbay J, Castro G, Wolin R, Kreutter KD, Maharoof U, Milligan C, Nishimura R, Pierce J, Schalk-Hihi C, Spurlino J, Urbanski M, Venkatesan H, Wang A, Woods C, Xue X, Edwards JP, Fourie AM, Leonard K.

Bioorg Med Chem Lett. 2017 May 1;27(9):2047-2057. doi: 10.1016/j.bmcl.2017.02.044. Epub 2017 Feb 21.

PMID:
28318945
21.

Sorafenib combined with HER-2 targeted vaccination can promote effective T cell immunity in vivo.

Sunay MM, Foote JB, Leatherman JM, Edwards JP, Armstrong TD, Nirschl CJ, Hicks J, Emens LA.

Int Immunopharmacol. 2017 May;46:112-123. doi: 10.1016/j.intimp.2017.02.028. Epub 2017 Mar 7.

22.

The adequacy of hepatopancreatobiliary training: How does operative exposure and perceived readiness in fellowship translate into subsequent practice?

Aubin JM, Bressan AK, Edwards JP, Grondin SC, Dixon E, Minter RM, Jeyarajah DR, Hansen P, Cooper AB, Ball CG.

Can J Surg. 2017 Apr;60(2):140-143.

23.

Clinical Development of Histamine H4 Receptor Antagonists.

Thurmond RL, Venable J, Savall B, La D, Snook S, Dunford PJ, Edwards JP.

Handb Exp Pharmacol. 2017;241:301-320. doi: 10.1007/164_2016_130. Review.

PMID:
28233185
24.

The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance.

Edwards JP, Hand TW, Morais da Fonseca D, Glass DD, Belkaid Y, Shevach EM.

Eur J Immunol. 2016 Jun;46(6):1480-9. doi: 10.1002/eji.201546204. Epub 2016 Apr 23.

25.

A Prospective Virtual Screening Study: Enriching Hit Rates and Designing Focus Libraries To Find Inhibitors of PI3Kδ and PI3Kγ.

Damm-Ganamet KL, Bembenek SD, Venable JW, Castro GG, Mangelschots L, Peeters DC, Mcallister HM, Edwards JP, Disepio D, Mirzadegan T.

J Med Chem. 2016 May 12;59(9):4302-13. doi: 10.1021/acs.jmedchem.5b01974. Epub 2016 Apr 28.

PMID:
27043133
26.

Management of pulmonary arterial bleeding in the post induction setting.

Edwards JP, Balderson SS, D'Amico TA.

J Vis Surg. 2016 Mar 16;2:53. doi: 10.21037/jovs.2016.03.08. eCollection 2016.

27.

Division of the bronchus: an approach to the intraoperative management of difficult lymphadenopathy.

Edwards JP, Balderson SS, D'Amico TA.

J Vis Surg. 2016 Mar 2;2:30. doi: 10.3978/j.issn.2221-2965.2016.02.03. eCollection 2016.

28.

Forecasting the impact of stereotactic ablative radiotherapy for early-stage lung cancer on the thoracic surgery workforce.

Edwards JP, Datta I, Hunt JD, Stefan K, Ball CG, Dixon E, Grondin SC.

Eur J Cardiothorac Surg. 2016 Jun;49(6):1599-606. doi: 10.1093/ejcts/ezv421. Epub 2016 Jan 21.

PMID:
26796110
29.

Has the quality of reporting of randomized controlled trials in thoracic surgery improved?

Edwards JP, Dharampal N, Chung W, Brar MS, Ball CG, Seto J, Grondin SC.

Eur J Cardiothorac Surg. 2016 May;49(5):1476-82. doi: 10.1093/ejcts/ezv375. Epub 2015 Oct 25.

PMID:
26503723
30.

Tear Fluid SIgA as a Noninvasive Biomarker of Mucosal Immunity and Common Cold Risk.

Hanstock HG, Walsh NP, Edwards JP, Fortes MB, Cosby SL, Nugent A, Curran T, Coyle PV, Ward MD, Yong XH.

Med Sci Sports Exerc. 2016 Mar;48(3):569-77. doi: 10.1249/MSS.0000000000000801.

PMID:
26496418
31.

The adequacy of Hepato-Pancreato-Biliary training: how closely do perceptions of fellows and programme directors align?

Bressan AK, Edwards JP, Grondin SC, Dixon E, Minter RM, Jeyarajah DR, Ball CG.

HPB (Oxford). 2015 Sep;17(9):791-5. doi: 10.1111/hpb.12457. Epub 2015 Jul 7.

32.

Hepato-pancreato-biliary surgery workforce in Canada.

Edwards JP, Bressan A, Dharampal N, Grondin SC, Datta I, Dixon E, Cleary SP, Barkun JS, Butte JM, Ball CG.

Can J Surg. 2015 Jun;58(3):212-5.

33.

Surgeons and lung cancer screening: rules of engagement.

Grondin SC, Edwards JP, Rocco G.

Thorac Surg Clin. 2015 May;25(2):175-84. doi: 10.1016/j.thorsurg.2014.11.004. Epub 2015 Jan 28. Review.

PMID:
25901561
34.

Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H4 receptor modulators.

Savall BM, Meduna SP, Tays K, Cai H, Thurmond RL, McGovern P, Gaul M, Zhao BP, Edwards JP.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):956-9. doi: 10.1016/j.bmcl.2014.12.027. Epub 2014 Dec 23.

PMID:
25595684
35.

The effect of pK(a) on pyrimidine/pyridine-derived histamine H4 ligands.

Savall BM, Meduna SP, Venable J, Wei J, Smith RC, Hack MD, Thurmond RL, McGovern P, Edwards JP.

Bioorg Med Chem Lett. 2014 Dec 1;24(23):5489-92. doi: 10.1016/j.bmcl.2014.10.013. Epub 2014 Oct 13.

PMID:
25455490
36.

Exercise Intensity and Duration Effects on In Vivo Immunity.

Diment BC, Fortes MB, Edwards JP, Hanstock HG, Ward MD, Dunstall HM, Friedmann PS, Walsh NP.

Med Sci Sports Exerc. 2015 Jul;47(7):1390-8. doi: 10.1249/MSS.0000000000000562.

PMID:
25380472
37.
38.

Release of active TGF-β1 from the latent TGF-β1/GARP complex on T regulatory cells is mediated by integrin β8.

Edwards JP, Thornton AM, Shevach EM.

J Immunol. 2014 Sep 15;193(6):2843-9. doi: 10.4049/jimmunol.1401102. Epub 2014 Aug 15.

39.

Methotrexate pharmacotherapy for implant-related temporomandibular joint pain: a case report.

Edwards JP, Peterson EJ, Durham J, Nixdorf DR.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Aug;118(2):e44-7. doi: 10.1016/j.oooo.2014.05.008. Epub 2014 May 21.

PMID:
25047933
40.

The impact of computed tomographic screening for lung cancer on the thoracic surgery workforce.

Edwards JP, Datta I, Hunt JD, Stefan K, Ball CG, Dixon E, Grondin SC.

Ann Thorac Surg. 2014 Aug;98(2):447-52. doi: 10.1016/j.athoracsur.2014.04.076. Epub 2014 Jun 21.

PMID:
24961839
41.

Identifying areas of weakness in thoracic surgery residency training: a comparison of the perceptions of residents and program directors.

Edwards JP, Schofield A, Paolucci EO, Schieman C, Kelly E, Servatyari R, Dixon E, Ball CG, Grondin SC.

J Surg Educ. 2014 May-Jun;71(3):360-6. doi: 10.1016/j.jsurg.2013.11.001. Epub 2014 Jan 2.

PMID:
24797852
42.

A novel approach for the accurate prediction of thoracic surgery workforce requirements in Canada.

Edwards JP, Datta I, Hunt JD, Stefan K, Ball CG, Dixon E, Grondin SC.

J Thorac Cardiovasc Surg. 2014 Jul;148(1):7-12. doi: 10.1016/j.jtcvs.2014.03.031. Epub 2014 Mar 26.

43.

Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H₄ receptor antagonists.

Savall BM, Chavez F, Tays K, Dunford PJ, Cowden JM, Hack MD, Wolin RL, Thurmond RL, Edwards JP.

J Med Chem. 2014 Mar 27;57(6):2429-39. doi: 10.1021/jm401727m. Epub 2014 Feb 21.

PMID:
24495018
44.

A rare cavernous hemangioma of the adrenal gland.

Edwards JP, Stuart HC, Urbanski SJ, Pasieka JL.

Int J Surg Case Rep. 2014;5(2):52-5. doi: 10.1016/j.ijscr.2013.11.003. Epub 2013 Nov 20.

45.

Analysis of milking characteristics in New Zealand dairy cows.

Edwards JP, Jago JG, Lopez-Villalobos N.

J Dairy Sci. 2014;97(1):259-69. doi: 10.3168/jds.2013-7051. Epub 2013 Nov 7.

46.

Milking efficiency of swingover herringbone parlours in pasture-based dairy systems.

Edwards JP, O'Brien B, Lopez-Villalobos N, Jago JG.

J Dairy Res. 2013 Nov;80(4):467-74. doi: 10.1017/S0022029913000393. Epub 2013 Sep 4.

PMID:
24000951
47.

Overmilking causes deterioration in teat-end condition of dairy cows in late lactation.

Edwards JP, O'Brien B, Lopez-Villalobos N, Jago JG.

J Dairy Res. 2013 Aug;80(3):344-8. doi: 10.1017/S0022029913000307. Epub 2013 Jun 28.

PMID:
23806206
48.

Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation.

Edwards JP, Fujii H, Zhou AX, Creemers J, Unutmaz D, Shevach EM.

J Immunol. 2013 Jun 1;190(11):5506-15. doi: 10.4049/jimmunol.1300199. Epub 2013 May 3.

49.

Milking efficiency for grazing dairy cows can be improved by increasing automatic cluster remover thresholds without applying premilking stimulation.

Edwards JP, Jago JG, Lopez-Villalobos N.

J Dairy Sci. 2013 Jun;96(6):3766-73. doi: 10.3168/jds.2012-6394. Epub 2013 Apr 5.

50.

Coherent spin control by electrical manipulation of the magnetic anisotropy.

George RE, Edwards JP, Ardavan A.

Phys Rev Lett. 2013 Jan 11;110(2):027601. Epub 2013 Jan 7.

PMID:
23383938

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