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Items: 1 to 50 of 60

1.

GLP-1 action in the mouse bed nucleus of the stria terminalis.

Williams DL, Lilly NA, Edwards IJ, Yao P, Richards JE, Trapp S.

Neuropharmacology. 2018 Mar 15;131:83-95. doi: 10.1016/j.neuropharm.2017.12.007. Epub 2017 Dec 6.

2.

Cholinergic Enhancement of Cell Proliferation in the Postnatal Neurogenic Niche of the Mammalian Spinal Cord.

Corns LF, Atkinson L, Daniel J, Edwards IJ, New L, Deuchars J, Deuchars SA.

Stem Cells. 2015 Sep;33(9):2864-76. doi: 10.1002/stem.2077. Epub 2015 Jun 26.

3.

Co-expression of GAD67 and choline acetyltransferase reveals a novel neuronal phenotype in the mouse medulla oblongata.

Gotts J, Atkinson L, Edwards IJ, Yanagawa Y, Deuchars SA, Deuchars J.

Auton Neurosci. 2015 Dec;193:22-30. doi: 10.1016/j.autneu.2015.05.003. Epub 2015 May 16.

4.

Highlights in basic autonomic neurosciences: Changes to the autonomic nervous system associated with healthy ageing.

Edwards IJ.

Auton Neurosci. 2014 Jul;183:1-3. doi: 10.1016/j.autneu.2014.04.004. Epub 2014 May 6. No abstract available.

PMID:
24862159
5.

Neck muscle afferents influence oromotor and cardiorespiratory brainstem neural circuits.

Edwards IJ, Lall VK, Paton JF, Yanagawa Y, Szabo G, Deuchars SA, Deuchars J.

Brain Struct Funct. 2015;220(3):1421-36. doi: 10.1007/s00429-014-0734-8. Epub 2014 Mar 5.

6.

A simple method to fluorescently label pericytes in the CNS and skeletal muscle.

Edwards IJ, Singh M, Morris S, Osborne L, Le Ruez T, Fuad M, Deuchars SA, Deuchars J.

Microvasc Res. 2013 Sep;89:164-8. doi: 10.1016/j.mvr.2013.05.008. Epub 2013 Jun 10.

7.

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

Edwards IJ, Bruce G, Lawrenson C, Howe L, Clapcote SJ, Deuchars SA, Deuchars J.

J Neurosci. 2013 Jun 12;33(24):9913-9. doi: 10.1523/JNEUROSCI.5584-12.2013.

8.

Fatty acid metabolites in rapidly proliferating breast cancer.

O'Flaherty JT, Wooten RE, Samuel MP, Thomas MJ, Levine EA, Case LD, Akman SA, Edwards IJ.

PLoS One. 2013 May 2;8(5):e63076. doi: 10.1371/journal.pone.0063076. Print 2013.

9.

Polyunsaturated fatty acids affect the localization and signaling of PIP3/AKT in prostate cancer cells.

Gu Z, Wu J, Wang S, Suburu J, Chen H, Thomas MJ, Shi L, Edwards IJ, Berquin IM, Chen YQ.

Carcinogenesis. 2013 Sep;34(9):1968-75. doi: 10.1093/carcin/bgt147. Epub 2013 Apr 30.

10.

Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice.

Kirshenbaum GS, Dawson N, Mullins JG, Johnston TH, Drinkhill MJ, Edwards IJ, Fox SH, Pratt JA, Brotchie JM, Roder JC, Clapcote SJ.

PLoS One. 2013;8(3):e60141. doi: 10.1371/journal.pone.0060141. Epub 2013 Mar 20.

11.

15-Lipoxygenase-1-mediated metabolism of docosahexaenoic acid is required for syndecan-1 signaling and apoptosis in prostate cancer cells.

Hu Y, Sun H, O'Flaherty JT, Edwards IJ.

Carcinogenesis. 2013 Jan;34(1):176-82. doi: 10.1093/carcin/bgs324. Epub 2012 Oct 11.

12.

15-lipoxygenase metabolites of docosahexaenoic acid inhibit prostate cancer cell proliferation and survival.

O'Flaherty JT, Hu Y, Wooten RE, Horita DA, Samuel MP, Thomas MJ, Sun H, Edwards IJ.

PLoS One. 2012;7(9):e45480. doi: 10.1371/journal.pone.0045480. Epub 2012 Sep 20.

13.

Proteoglycans in prostate cancer.

Edwards IJ.

Nat Rev Urol. 2012 Feb 21;9(4):196-206. doi: 10.1038/nrurol.2012.19. Review.

PMID:
22349653
14.

Effect of dietary polyunsaturated fatty acids on castration-resistant Pten-null prostate cancer.

Wang S, Wu J, Suburu J, Gu Z, Cai J, Axanova LS, Cramer SD, Thomas MJ, Perry DL, Edwards IJ, Mucci LA, Sinnott JA, Loda MF, Sui G, Berquin IM, Chen YQ.

Carcinogenesis. 2012 Feb;33(2):404-12. doi: 10.1093/carcin/bgr290. Epub 2011 Dec 8.

15.

Polyunsaturated fatty acid metabolism in prostate cancer.

Berquin IM, Edwards IJ, Kridel SJ, Chen YQ.

Cancer Metastasis Rev. 2011 Dec;30(3-4):295-309. doi: 10.1007/s10555-011-9299-7. Review.

16.

Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway.

Sun H, Hu Y, Gu Z, Owens RT, Chen YQ, Edwards IJ.

Carcinogenesis. 2011 Oct;32(10):1518-24. doi: 10.1093/carcin/bgr132. Epub 2011 Jul 18.

17.

Endogenous synthesis of n-3 polyunsaturated fatty acids in Fat-1 mice is associated with increased mammary gland and liver syndecan-1.

Sun H, Hu Y, Gu Z, Wilson MD, Chen YQ, Rudel LL, Willingham MC, Edwards IJ.

PLoS One. 2011;6(5):e20502. doi: 10.1371/journal.pone.0020502. Epub 2011 May 31.

18.

Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancer.

Hu Y, Sun H, Owens RT, Gu Z, Wu J, Chen YQ, O'Flaherty JT, Edwards IJ.

Neoplasia. 2010 Oct;12(10):826-36.

19.

Kv3.3 immunoreactivity in the vestibular nuclear complex of the rat with focus on the medial vestibular nucleus: targeting of Kv3.3 neurones by terminals positive for vesicular glutamate transporter 1.

Brooke RE, Corns L, Edwards IJ, Deuchars J.

Brain Res. 2010 Jul 23;1345:45-58. doi: 10.1016/j.brainres.2010.05.020. Epub 2010 May 13.

PMID:
20471378
20.

Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited.

Bütikofer P, Greganova E, Liu YC, Edwards IJ, Lehane MJ, Acosta-Serrano A.

Biochem J. 2010 May 27;428(3):409-18. doi: 10.1042/BJ20100229.

PMID:
20345369
21.

Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways.

Hu Y, Sun H, Owens RT, Wu J, Chen YQ, Berquin IM, Perry D, O'Flaherty JT, Edwards IJ.

Neoplasia. 2009 Oct;11(10):1042-53.

22.
23.

Omega-3 Fatty Acids and PPARgamma in Cancer.

Edwards IJ, O'Flaherty JT.

PPAR Res. 2008;2008:358052. doi: 10.1155/2008/358052.

24.

Multi-targeted therapy of cancer by omega-3 fatty acids.

Berquin IM, Edwards IJ, Chen YQ.

Cancer Lett. 2008 Oct 8;269(2):363-77. doi: 10.1016/j.canlet.2008.03.044. Epub 2008 May 13. Review.

25.

In vivo and in vitro regulation of syndecan 1 in prostate cells by n-3 polyunsaturated fatty acids.

Edwards IJ, Sun H, Hu Y, Berquin IM, O'Flaherty JT, Cline JM, Rudel LL, Chen YQ.

J Biol Chem. 2008 Jun 27;283(26):18441-9. doi: 10.1074/jbc.M802107200. Epub 2008 Apr 30.

26.

Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells.

Sun H, Berquin IM, Owens RT, O'Flaherty JT, Edwards IJ.

Cancer Res. 2008 Apr 15;68(8):2912-9. doi: 10.1158/0008-5472.CAN-07-2305.

27.

Asparagine deamidation and the role of higher order protein structure.

Rivers J, McDonald L, Edwards IJ, Beynon RJ.

J Proteome Res. 2008 Mar;7(3):921-7. doi: 10.1021/pr070425l. Epub 2008 Feb 5.

PMID:
18247555
28.

Dietary fat-gene interactions in cancer.

Chen YQ, Edwards IJ, Kridel SJ, Thornburg T, Berquin IM.

Cancer Metastasis Rev. 2007 Dec;26(3-4):535-51. Review.

PMID:
17849170
29.

The neurochemically diverse intermedius nucleus of the medulla as a source of excitatory and inhibitory synaptic input to the nucleus tractus solitarii.

Edwards IJ, Dallas ML, Poole SL, Milligan CJ, Yanagawa Y, Szabó G, Erdélyi F, Deuchars SA, Deuchars J.

J Neurosci. 2007 Aug 1;27(31):8324-33.

30.

Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids.

Berquin IM, Min Y, Wu R, Wu J, Perry D, Cline JM, Thomas MJ, Thornburg T, Kulik G, Smith A, Edwards IJ, D'Agostino R, Zhang H, Wu H, Kang JX, Chen YQ.

J Clin Invest. 2007 Jul;117(7):1866-75.

31.

Omega-3 fatty acids and cancer risk.

Chen YQ, Berquin IM, Daniel LW, Edwards IJ, O'Flaherty JT, Thomas MJ, Tooze JA, Wykle B.

JAMA. 2006 Jul 19;296(3):282; author reply 282. No abstract available.

PMID:
16849660
32.

HCN1 ion channel immunoreactivity in spinal cord and medulla oblongata.

Milligan CJ, Edwards IJ, Deuchars J.

Brain Res. 2006 Apr 7;1081(1):79-91. Epub 2006 Feb 28.

PMID:
16503331
33.

Omega-3 polyunsaturated fatty acids regulate syndecan-1 expression in human breast cancer cells.

Sun H, Berquin IM, Edwards IJ.

Cancer Res. 2005 May 15;65(10):4442-7.

34.

Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin.

Edwards IJ, Berquin IM, Sun H, O'flaherty JT, Daniel LW, Thomas MJ, Rudel LL, Wykle RL, Chen YQ.

Clin Cancer Res. 2004 Dec 15;10(24):8275-83.

35.

Arterial heparan sulfate is negatively associated with hyperglycemia and atherosclerosis in diabetic monkeys.

Edwards IJ, Wagner JD, Vogl-Willis CA, Litwak KN, Cefalu WT.

Cardiovasc Diabetol. 2004 Apr 29;3:6.

36.
37.

High glucose-induced alterations in subendothelial matrix perlecan leads to increased monocyte binding.

Vogl-Willis CA, Edwards IJ.

Arterioscler Thromb Vasc Biol. 2004 May;24(5):858-63. Epub 2004 Mar 18.

PMID:
15031130
38.

Improved glucose control decreases the interaction of plasma low-density lipoproteins with arterial proteoglycans.

Edwards IJ, Terry JG, Bell-Farrow AD, Cefalu WT.

Metabolism. 2002 Oct;51(10):1223-9.

PMID:
12370838
39.

Caloric restriction lowers plasma lipoprotein (a) in male but not female rhesus monkeys.

Edwards IJ, Rudel LL, Terry JG, Kemnitz JW, Weindruch R, Zaccaro DJ, Cefalu WT.

Exp Gerontol. 2001 Aug;36(8):1413-8.

PMID:
11602214
40.

In vitro oxidation of low-density lipoprotein in two species of nonhuman primates subjected to caloric restriction.

Cefalu WT, Terry JG, Thomas MJ, Morgan TM, Edwards IJ, Rudel LL, Kemnitz JW, Weindruch R.

J Gerontol A Biol Sci Med Sci. 2000 Jul;55(7):B355-61.

PMID:
10898249
41.

Influence of caloric restriction on the development of atherosclerosis in nonhuman primates: progress to date.

Cefalu WT, Wagner JD, Bell-Farrow AD, Edwards IJ, Terry JG, Weindruch R, Kemnitz JW.

Toxicol Sci. 1999 Dec;52(2 Suppl):49-55.

PMID:
10630590
42.

Glycation of plasma low density lipoproteins increases interaction with arterial proteoglycans.

Edwards IJ, Wagner JD, Litwak KN, Rudel LL, Cefalu WT.

Diabetes Res Clin Pract. 1999 Oct;46(1):9-18.

PMID:
10580610
43.

Caloric restriction in rhesus monkeys reduces low density lipoprotein interaction with arterial proteoglycans.

Edwards IJ, Rudel LL, Terry JG, Kemnitz JW, Weindruch R, Cefalu WT.

J Gerontol A Biol Sci Med Sci. 1998 Nov;53(6):B443-8.

PMID:
9823741
44.

Effects of contraceptive estrogen and progestin on the atherogenic potential of plasma LDLs in cynomolgus monkeys.

Manning JM, Edwards IJ, Wagner WD, Wagner JD, Adams MR, Parks JS.

Arterioscler Thromb Vasc Biol. 1997 Jul;17(7):1216-23.

PMID:
9261249
45.

Effects of hormone replacement modalities on low density lipoprotein composition and distribution in ovariectomized cynomolgus monkeys.

Manning JM, Campos G, Edwards IJ, Wagner WD, Wagner JD, Adams MR, Parks JS.

Atherosclerosis. 1996 Apr 5;121(2):217-29.

PMID:
9125296
46.

Differentiated macrophages synthesize a heparan sulfate proteoglycan and an oversulfated chondroitin sulfate proteoglycan that bind lipoprotein lipase.

Edwards IJ, Xu H, Obunike JC, Goldberg IJ, Wagner WD.

Arterioscler Thromb Vasc Biol. 1995 Mar;15(3):400-9.

PMID:
7749850
47.

Dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans.

Manning JM, Gebre AK, Edwards IJ, Wagner WD, Rudel LL, Parks JS.

Lipids. 1994 Sep;29(9):635-41.

PMID:
7815898
48.

Interleukin-1 upregulates decorin production by arterial smooth muscle cells.

Edwards IJ, Xu H, Wright MJ, Wagner WD.

Arterioscler Thromb. 1994 Jul;14(7):1032-9.

PMID:
8018657
49.

Cellular differences in lipoprotein lipase-mediated uptake of low density lipoproteins.

Obunike JC, Edwards IJ, Rumsey SC, Curtiss LK, Wagner WD, Deckelbaum RJ, Goldberg IJ.

J Biol Chem. 1994 May 6;269(18):13129-35.

50.

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