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Items: 1 to 50 of 164

1.

Allometric scaling of skin thickness, elasticity, viscoelasticity to mass for micro-medical device translation: from mice, rats, rabbits, pigs to humans.

Wei JCJ, Edwards GA, Martin DJ, Huang H, Crichton ML, Kendall MAF.

Sci Rep. 2017 Nov 21;7(1):15885. doi: 10.1038/s41598-017-15830-7.

2.

Correlating in Vitro Solubilization and Supersaturation Profiles with in Vivo Exposure for Lipid Based Formulations of the CETP Inhibitor CP-532,623.

McEvoy CL, Trevaskis NL, Feeney OM, Edwards GA, Perlman ME, Ambler CM, Porter CJH.

Mol Pharm. 2017 Dec 4;14(12):4525-4538. doi: 10.1021/acs.molpharmaceut.7b00660. Epub 2017 Nov 9.

PMID:
29076741
3.

Flawed Theories to Explain Child Physical Abuse: What Are the Medical-Legal Consequences?

Leventhal JM, Edwards GA.

JAMA. 2017 Oct 10;318(14):1317-1318. doi: 10.1001/jama.2017.11703. No abstract available.

PMID:
28975235
4.

5-Benzylidene-4-oxazolidinones potently inhibit biofilm formation in Methicillin-resistant Staphylococcus aureus.

Edwards GA, Shymanska NV, Pierce JG.

Chem Commun (Camb). 2017 Jun 29;53(53):7353-7356. doi: 10.1039/c7cc03626d.

5.

Characterization of Bombyx mori and Antheraea pernyi silk fibroins and their blends as potential biomaterials.

Suzuki S, Chirila TV, Edwards GA.

Prog Biomater. 2016 Dec;5(3-4):193-198. Epub 2016 Oct 27.

6.

Lymphatic Transport and Lymphocyte Targeting of a Triglyceride Mimetic Prodrug Is Enhanced in a Large Animal Model: Studies in Greyhound Dogs.

Han S, Hu L, Gracia, Quach T, Simpson JS, Edwards GA, Trevaskis NL, Porter CJ.

Mol Pharm. 2016 Oct 3;13(10):3351-3361. Epub 2016 Sep 21.

PMID:
27608166
7.

Management of Bennett's fractures: a review of treatment outcomes.

Edwards GA, Giddins GE.

J Hand Surg Eur Vol. 2017 Feb;42(2):201-203. doi: 10.1177/1753193416642691. Epub 2016 Sep 28. Review. No abstract available.

PMID:
27066999
8.

Major complications associated with fork-based and screw-based tibial tuberosity advancement implants: 438 cases.

Edwards GA, Hosgood G, Hancock RB, Stubbs WP, Jackson AH.

Can Vet J. 2016 Apr;57(4):415-20.

9.

Rigid removable cover for dorsal wound protection and tube fixation in pigs.

Stynes GD, Kiroff GK, Morrison WA, Edwards GA, Page RS, Kirkland MA.

Aust Vet J. 2016 Apr;94(4):111-6. doi: 10.1111/avj.12424.

PMID:
27021892
10.

Response to Edwards GA. Mimics of child abuse: Can choking explain abusive head trauma?

Edwards GA.

J Forensic Leg Med. 2016 Apr;39:135-7. doi: 10.1016/j.jflm.2016.01.031. Epub 2016 Feb 3. No abstract available.

PMID:
26878607
11.

Incorporation of Human Recombinant Tropoelastin into Silk Fibroin Membranes with the View to Repairing Bruch's Membrane.

Shadforth AM, Suzuki S, Alzonne R, Edwards GA, Richardson NA, Chirila TV, Harkin DG.

J Funct Biomater. 2015 Sep 16;6(3):946-62. doi: 10.3390/jfb6030946.

12.

Mimics of child abuse: Can choking explain abusive head trauma?

Edwards GA.

J Forensic Leg Med. 2015 Oct;35:33-7. doi: 10.1016/j.jflm.2015.06.012. Epub 2015 Jul 3. Review.

PMID:
26344456
13.

Treatment of Silk Fibroin with Poly(ethylene glycol) for the Enhancement of Corneal Epithelial Cell Growth.

Suzuki S, Dawson RA, Chirila TV, Shadforth AM, Hogerheyde TA, Edwards GA, Harkin DG.

J Funct Biomater. 2015 May 29;6(2):345-66. doi: 10.3390/jfb6020345.

14.

Allyl sulphides in olefin metathesis: catalyst considerations and traceless promotion of ring-closing metathesis.

Edwards GA, Culp PA, Chalker JM.

Chem Commun (Camb). 2015 Jan 11;51(3):515-8. doi: 10.1039/c4cc07932a.

PMID:
25410944
15.

New engineering treatment of bovine pericardium confers outstanding resistance to calcification in mitral and pulmonary implantations in a juvenile sheep model.

Brizard CP, Brink J, Horton SB, Edwards GA, Galati JC, Neethling WM.

J Thorac Cardiovasc Surg. 2014 Dec;148(6):3194-201. doi: 10.1016/j.jtcvs.2014.08.002. Epub 2014 Aug 7.

16.

In vitro-in vivo evaluation of lipid based formulations of the CETP inhibitors CP-529,414 (torcetrapib) and CP-532,623.

McEvoy CL, Trevaskis NL, Edwards GA, Perlman ME, Ambler CM, Mack MC, Brockhurst B, Porter CJ.

Eur J Pharm Biopharm. 2014 Nov;88(3):973-85. doi: 10.1016/j.ejpb.2014.08.006. Epub 2014 Aug 23.

PMID:
25152213
17.

Melamine and melamine-formaldehyde polymers as ligands for palladium and application to Suzuki-Miyaura cross-coupling reactions in sustainable solvents.

Edwards GA, Trafford MA, Hamilton AE, Buxton AM, Bardeaux MC, Chalker JM.

J Org Chem. 2014 Mar 7;79(5):2094-104. doi: 10.1021/jo402799t. Epub 2014 Feb 17.

PMID:
24533440
18.

Non-linear increases in danazol exposure with dose in older vs. younger beagle dogs: the potential role of differences in bile salt concentration, thermodynamic activity, and formulation digestion.

Anby MU, Williams HD, Feeney O, Edwards GA, Benameur H, Pouton CW, Porter CJ.

Pharm Res. 2014 Jun;31(6):1536-52. doi: 10.1007/s11095-013-1260-8. Epub 2014 Jan 30.

PMID:
24477676
19.

Organization of mixed dimethyldioctadecylammonium and choline modifiers on the surface of synthetic hectorite.

Andriani Y, Jack KS, Gilbert EP, Edwards GA, Schiller TL, Strounina E, Osman AF, Martin DJ.

J Colloid Interface Sci. 2013 Nov 1;409:72-9. doi: 10.1016/j.jcis.2013.07.055. Epub 2013 Aug 2.

PMID:
23978291
20.

In vitro biostability of poly(dimethyl siloxane/hexamethylene oxide)-based polyurethane/layered silicate nanocomposites.

Andriani Y, Morrow IC, Taran E, Edwards GA, Schiller TL, Osman AF, Martin DJ.

Acta Biomater. 2013 Sep;9(9):8308-17. doi: 10.1016/j.actbio.2013.05.021. Epub 2013 May 30.

PMID:
23727246
21.

An unusual cause of Grey Turner's sign.

Gosling OB, Hunter AE, Edwards GA, Squires B.

BMJ Case Rep. 2013 May 15;2013. pii: bcr2013008836. doi: 10.1136/bcr-2013-008836.

22.

Effect of the sterilization method on the properties of Bombyx mori silk fibroin films.

George KA, Shadforth AM, Chirila TV, Laurent MJ, Stephenson SA, Edwards GA, Madden PW, Hutmacher DW, Harkin DG.

Mater Sci Eng C Mater Biol Appl. 2013 Mar 1;33(2):668-74. doi: 10.1016/j.msec.2012.10.016. Epub 2012 Nov 2.

PMID:
25427472
23.

Silica-lipid hybrid (SLH) formulations enhance the oral bioavailability and efficacy of celecoxib: An in vivo evaluation.

Nguyen TH, Tan A, Santos L, Ngo D, Edwards GA, Porter CJ, Prestidge CA, Boyd BJ.

J Control Release. 2013 Apr 10;167(1):85-91. doi: 10.1016/j.jconrel.2013.01.012. Epub 2013 Jan 23.

PMID:
23353808
24.

Lipid digestion as a trigger for supersaturation: evaluation of the impact of supersaturation stabilization on the in vitro and in vivo performance of self-emulsifying drug delivery systems.

Anby MU, Williams HD, McIntosh M, Benameur H, Edwards GA, Pouton CW, Porter CJ.

Mol Pharm. 2012 Jul 2;9(7):2063-79. doi: 10.1021/mp300164u. Epub 2012 Jun 15.

PMID:
22656917
25.

Use of a TTA plate for correction of severe patella baja in a Chihuahua.

Edwards GA, Jackson AH.

J Am Anim Hosp Assoc. 2012 Mar-Apr;48(2):113-7. doi: 10.5326/JAAHA-MS-5686. Epub 2012 Jan 19.

PMID:
22267177
26.

A highly elastic and adhesive gelatin tissue sealant for gastrointestinal surgery and colon anastomosis.

Vuocolo T, Haddad R, Edwards GA, Lyons RE, Liyou NE, Werkmeister JA, Ramshaw JA, Elvin CM.

J Gastrointest Surg. 2012 Apr;16(4):744-52. doi: 10.1007/s11605-011-1771-8. Epub 2011 Nov 12.

PMID:
22081305
27.

Dislocation of the knee: an epidemic in waiting?

Edwards GA, Sarasin SM, Davies AP.

J Emerg Med. 2013 Jan;44(1):68-71. doi: 10.1016/j.jemermed.2011.06.064. Epub 2011 Nov 6.

PMID:
22056550
28.

A highly elastic tissue sealant based on photopolymerised gelatin.

Elvin CM, Vuocolo T, Brownlee AG, Sando L, Huson MG, Liyou NE, Stockwell PR, Lyons RE, Kim M, Edwards GA, Johnson G, McFarland GA, Ramshaw JA, Werkmeister JA.

Biomaterials. 2010 Nov;31(32):8323-31. doi: 10.1016/j.biomaterials.2010.07.032. Epub 2010 Aug 1.

PMID:
20674967
29.

Femoral component failure in canine cemented total hip replacement: a report of two cases.

Yates GD, Wasik SM, Edwards GA.

Aust Vet J. 2010 Jun;88(6):225-30. doi: 10.1111/j.1751-0813.2010.00574.x.

PMID:
20553571
30.

Atrial electrophysiology is altered by acute hypercapnia but not hypoxemia: implications for promotion of atrial fibrillation in pulmonary disease and sleep apnea.

Stevenson IH, Roberts-Thomson KC, Kistler PM, Edwards GA, Spence S, Sanders P, Kalman JM.

Heart Rhythm. 2010 Sep;7(9):1263-70. doi: 10.1016/j.hrthm.2010.03.020. Epub 2010 Mar 22.

PMID:
20338265
31.

The role of the intestinal lymphatics in the absorption of two highly lipophilic cholesterol ester transfer protein inhibitors (CP524,515 and CP532,623).

Trevaskis NL, McEvoy CL, McIntosh MP, Edwards GA, Shanker RM, Charman WN, Porter CJ.

Pharm Res. 2010 May;27(5):878-93. doi: 10.1007/s11095-010-0083-0. Epub 2010 Mar 11.

PMID:
20221896
32.

Human cord blood stem cells enhance neonatal right ventricular function in an ovine model of right ventricular training.

Davies B, Elwood NJ, Li S, Cullinane F, Edwards GA, Newgreen DF, Brizard CP.

Ann Thorac Surg. 2010 Feb;89(2):585-93, 593.e1-4. doi: 10.1016/j.athoracsur.2009.10.035.

PMID:
20103347
33.

Performance monitoring in hip fracture surgery--how big a database do we really need?

Edwards GA, Metcalfe AJ, Johansen A, O'Doherty D.

Injury. 2010 Apr;41(4):374-6. doi: 10.1016/j.injury.2009.10.006. Epub 2009 Nov 7.

PMID:
19897187
34.

Lymphatic transport of Methylnortestosterone undecanoate (MU) and the bioavailability of methylnortestosterone are highly sensitive to the mass of coadministered lipid after oral administration of MU.

White KL, Nguyen G, Charman WN, Edwards GA, Faassen WA, Porter CJ.

J Pharmacol Exp Ther. 2009 Nov;331(2):700-9. doi: 10.1124/jpet.109.154542. Epub 2009 Aug 20.

PMID:
19696095
35.

Evaluation of photo-crosslinked fibrinogen as a rapid and strong tissue adhesive.

Elvin CM, Danon SJ, Brownlee AG, White JF, Hickey M, Liyou NE, Edwards GA, Ramshaw JA, Werkmeister JA.

J Biomed Mater Res A. 2010 May;93(2):687-95. doi: 10.1002/jbm.a.32572.

PMID:
19610050
36.

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism.

Trevaskis NL, Shackleford DM, Charman WN, Edwards GA, Gardin A, Appel-Dingemanse S, Kretz O, Galli B, Porter CJ.

Pharm Res. 2009 Jun;26(6):1486-95. doi: 10.1007/s11095-009-9860-z. Epub 2009 Mar 12.

PMID:
19280324
37.

Expert systems for clinical pathology reporting.

Edwards GA.

Clin Biochem Rev. 2008 Aug;29 Suppl 1:S105-9.

38.

Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs.

Cuiné JF, McEvoy CL, Charman WN, Pouton CW, Edwards GA, Benameur H, Porter CJ.

J Pharm Sci. 2008 Feb;97(2):995-1012.

PMID:
18064698
39.

Lymphatic absorption of subcutaneously administered proteins: influence of different injection sites on the absorption of darbepoetin alfa using a sheep model.

Kota J, Machavaram KK, McLennan DN, Edwards GA, Porter CJ, Charman SA.

Drug Metab Dispos. 2007 Dec;35(12):2211-7. Epub 2007 Sep 17.

PMID:
17875672
40.

Recurrent rectal prolapse caused by colonic duplication in a dog.

Landon BP, Abraham LA, Charles JA, Edwards GA.

Aust Vet J. 2007 Sep;85(9):381-5.

PMID:
17760944
41.
42.

Atrial electrical and structural abnormalities in an ovine model of chronic blood pressure elevation after prenatal corticosteroid exposure: implications for development of atrial fibrillation.

Kistler PM, Sanders P, Dodic M, Spence SJ, Samuel CS, Zhao C, Charles JA, Edwards GA, Kalman JM.

Eur Heart J. 2006 Dec;27(24):3045-56. Epub 2006 Nov 10.

PMID:
17098760
43.

The absorption of darbepoetin alfa occurs predominantly via the lymphatics following subcutaneous administration to sheep.

McLennan DN, Porter CJ, Edwards GA, Heatherington AC, Martin SW, Charman SA.

Pharm Res. 2006 Sep;23(9):2060-6. Epub 2006 Aug 9.

PMID:
16951999
44.

Lymphatic absorption is the primary contributor to the systemic availability of epoetin Alfa following subcutaneous administration to sheep.

McLennan DN, Porter CJ, Edwards GA, Martin SW, Heatherington AC, Charman SA.

J Pharmacol Exp Ther. 2005 Apr;313(1):345-51. Epub 2004 Dec 3.

PMID:
15579493
45.
46.

Autoaugmentation gastrocystoplasty: further studies of the sheep model.

Close CE, Anderson PD, Edwards GA, Mitchell ME, Dewan PA.

BJU Int. 2004 Sep;94(4):658-62.

47.

Efficacy of combined cyclosporine A and ketoconazole treatment of anal furunculosis.

O'Neill T, Edwards GA, Holloway S.

J Small Anim Pract. 2004 May;45(5):238-43.

PMID:
15163050
48.

Evaluation of closed pericardial patch grafting for management of severe pulmonic stenosis.

Staudte KL, Gibson NR, Read RA, Edwards GA.

Aust Vet J. 2004 Jan-Feb;82(1-2):33-7.

PMID:
15088955
50.

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