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Secondary forest fragments offer important carbon-biodiversity co-benefits.

Matos FAR, Magnago LFS, Aquila Chan Miranda C, de Menezes LFT, Gastauer M, Safar NVH, Schaefer CEGR, Da Silva MP, Simonelli M, Edwards FA, Martins SV, Meira-Neto JAA, Edwards DP.

Glob Chang Biol. 2019 Sep 4. doi: 10.1111/gcb.14824. [Epub ahead of print]


The impact of secondary forest regeneration on ground-dwelling ant communities in the Tropical Andes.

Hethcoat MG, King BJ, Castiblanco FF, Ortiz-Sepúlveda CM, Achiardi FCP, Edwards FA, Medina C, Gilroy JJ, Haugaasen T, Edwards DP.

Oecologia. 2019 Sep 4. doi: 10.1007/s00442-019-04497-8. [Epub ahead of print]


FragSAD: A database of diversity and species abundance distributions from habitat fragments.

Chase JM, Liebergesell M, Sagouis A, May F, Blowes SA, Berg Å, Bernard E, Brosi BJ, Cadotte MW, Cayuela L, Chiarello AG, Cosson JF, Cresswell W, Dami FD, Dauber J, Dickman CR, Didham RK, Edwards DP, Farneda FZ, Gavish Y, Gonçalves-Souza T, Guadagnin DL, Henry M, López-Baucells A, Kappes H, MacNally R, Manu S, Martensen AC, McCollin D, Meyer CFJ, Neckel-Oliveira S, Nogueira A, Pons JM, Raheem DC, Ramos FN, Rocha R, Sam K, Slade E, Stireman JO III, Struebig MJ, Vasconcelos H, Ziv Y.

Ecology. 2019 Aug 5. doi: 10.1002/ecy.2861. [Epub ahead of print]


Phylogenetic and Trait-Based Prediction of Extinction Risk for Data-Deficient Amphibians.

González-Del-Pliego P, Freckleton RP, Edwards DP, Koo MS, Scheffers BR, Pyron RA, Jetz W.

Curr Biol. 2019 May 6;29(9):1557-1563.e3. doi: 10.1016/j.cub.2019.04.005.


Progesterone receptor isoform B expression in pulmonary neuroendocrine cells decreases cell proliferation.

Asavasupreechar T, Saito R, Edwards DP, Sasano H, Boonyaratanakornkit V.

J Steroid Biochem Mol Biol. 2019 Jun;190:212-223. doi: 10.1016/j.jsbmb.2019.03.022. Epub 2019 Mar 26.


Land-sparing agriculture sustains higher levels of avian functional diversity than land sharing.

Cannon PG, Gilroy JJ, Tobias JA, Anderson A, Haugaasen T, Edwards DP.

Glob Chang Biol. 2019 May;25(5):1576-1590. doi: 10.1111/gcb.14601. Epub 2019 Mar 13.


UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors.

Finnerty BM, Moore M, Verma A, Aronova A, Huang S, Edwards DP, Chen Z, Seandel M, Scognamiglio T, Du N, Elemento O, Zarnegar R, Min IM, Fahey TJ.

Endocr Relat Cancer. 2019 Apr 1;26(4):411-423. doi: 10.1530/ERC-18-0507. Epub 2019 Jan 1.


Increasing Adherence to Evidence-Based Clinical Practice.

Knighton AJ, McLaughlin M, Blackburn R, Wolfe D, Andrews S, Hellewell JL, Moore R, Edwards DP, Allen TL, Srivastava R.

Qual Manag Health Care. 2019 Jan/Mar;28(1):65-67. doi: 10.1097/QMH.0000000000000195. No abstract available.


Rapid and scale-independent microfluidic manufacture of liposomes entrapping protein incorporating in-line purification and at-line size monitoring.

Forbes N, Hussain MT, Briuglia ML, Edwards DP, Horst JHT, Szita N, Perrie Y.

Int J Pharm. 2019 Feb 10;556:68-81. doi: 10.1016/j.ijpharm.2018.11.060. Epub 2018 Nov 29.


Correction to: The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast.

Villanueva H, Grimm SL, Dhamne S, Rajapakshe K, Visbal AP, Davis CM, Ehli EA, Hartig SM, Coarfa C, Edwards DP.

J Mammary Gland Biol Neoplasia. 2019 Mar;24(1):109-110. doi: 10.1007/s10911-018-9421-3.


Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes.

Bu W, Liu Z, Jiang W, Nagi C, Huang S, Edwards DP, Jo E, Mo Q, Creighton CJ, Hilsenbeck SG, Leavitt AD, Lewis MT, Wong STC, Li Y.

Cancer Res. 2019 Jan 1;79(1):61-71. doi: 10.1158/0008-5472.CAN-18-1087. Epub 2018 Nov 6.


The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast.

Villanueva H, Grimm S, Dhamne S, Rajapakshe K, Visbal A, Davis CM, Ehli EA, Hartig SM, Coarfa C, Edwards DP.

J Mammary Gland Biol Neoplasia. 2018 Dec;23(4):237-248. doi: 10.1007/s10911-018-9416-0. Epub 2018 Oct 18. Review. Erratum in: J Mammary Gland Biol Neoplasia. 2018 Nov 21;:.


Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice.

Shrestha AK, Bettini ML, Menon RT, Gopal VYN, Huang S, Edwards DP, Pammi M, Barrios R, Shivanna B.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L229-L244. doi: 10.1152/ajplung.00560.2017. Epub 2018 Oct 11.


TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.

Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG.

Oncoimmunology. 2018 Jul 26;7(10):e1490853. doi: 10.1080/2162402X.2018.1490853. eCollection 2018.


Combined impacts of deforestation and wildlife trade on tropical biodiversity are severely underestimated.

Symes WS, Edwards DP, Miettinen J, Rheindt FE, Carrasco LR.

Nat Commun. 2018 Oct 3;9(1):4052. doi: 10.1038/s41467-018-06579-2.


Quantifying carbon stocks in shifting cultivation landscapes under divergent management scenarios relevant to REDD.

Borah JR, Evans KL, Edwards DP.

Ecol Appl. 2018 Sep;28(6):1581-1593. doi: 10.1002/eap.1764. Epub 2018 Jul 25.


A mouse model engineered to conditionally express the progesterone receptor-B isoform.

Hai L, Szwarc MM, Wetendorf M, Wu SP, Peavey MC, Grimm SL, Edwards DP, DeMayo FJ, Lydon JP.

Genesis. 2018 Aug;56(8):e23223. doi: 10.1002/dvg.23223. Epub 2018 Aug 10.


Ecosystem-based management of coral reefs under climate change.

Harvey BJ, Nash KL, Blanchard JL, Edwards DP.

Ecol Evol. 2018 May 20;8(12):6354-6368. doi: 10.1002/ece3.4146. eCollection 2018 Jun. Review.


Impacts of tropical forest disturbance on species vital rates.

Cosset CCP, Gilroy JJ, Edwards DP.

Conserv Biol. 2019 Feb;33(1):66-75. doi: 10.1111/cobi.13182. Epub 2018 Sep 27.


Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer.

Giles ED, Jindal S, Wellberg EA, Schedin T, Anderson SM, Thor AD, Edwards DP, MacLean PS, Schedin P.

Breast Cancer Res. 2018 Jun 14;20(1):50. doi: 10.1186/s13058-018-0974-2.


An Efficient, Clinically-Natural Electronic Medical Record System that Produces Computable Data.

James BC, Edwards DP, James AF, Bradshaw RL, White KS, Wood C, Huff S.

EGEMS (Wash DC). 2017 Dec 15;5(3):8. doi: 10.5334/egems.202.


Debugging diversity - a pan-continental exploration of the potential of terrestrial blood-feeding leeches as a vertebrate monitoring tool.

Schnell IB, Bohmann K, Schultze SE, Richter SR, Murray DC, Sinding MS, Bass D, Cadle JE, Campbell MJ, Dolch R, Edwards DP, Gray TNE, Hansen T, Hoa ANQ, Noer CL, Heise-Pavlov S, Sander Pedersen AF, Ramamonjisoa JC, Siddall ME, Tilker A, Traeholt C, Wilkinson N, Woodcock P, Yu DW, Bertelsen MF, Bunce M, Gilbert MTP.

Mol Ecol Resour. 2018 Nov;18(6):1282-1298. doi: 10.1111/1755-0998.12912. Epub 2018 Jul 5.


TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis.

Singh R, Karri D, Shen H, Shao J, Dasgupta S, Huang S, Edwards DP, Ittmann MM, O'Malley BW, Yi P.

J Clin Invest. 2018 Jul 2;128(7):3129-3143. doi: 10.1172/JCI96060. Epub 2018 Jun 18.


Protecting tropical forests from the rapid expansion of rubber using carbon payments.

Warren-Thomas EM, Edwards DP, Bebber DP, Chhang P, Diment AN, Evans TD, Lambrick FH, Maxwell JF, Nut M, O'Kelly HJ, Theilade I, Dolman PM.

Nat Commun. 2018 Mar 2;9(1):911. doi: 10.1038/s41467-018-03287-9.


Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers.

Mundt F, Rajput S, Li S, Ruggles KV, Mooradian AD, Mertins P, Gillette MA, Krug K, Guo Z, Hoog J, Erdmann-Gilmore P, Primeau T, Huang S, Edwards DP, Wang X, Wang X, Kawaler E, Mani DR, Clauser KR, Gao F, Luo J, Davies SR, Johnson GL, Huang KL, Yoon CJ, Ding L, Fenyö D, Ellis MJ, Townsend RR, Held JM, Carr SA, Ma CX.

Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990. Epub 2018 Feb 22.


Tropical forests are thermally buffered despite intensive selective logging.

Senior RA, Hill JK, Benedick S, Edwards DP.

Glob Chang Biol. 2018 Mar;24(3):1267-1278. doi: 10.1111/gcb.13914. Epub 2017 Oct 20.


A pantropical analysis of the impacts of forest degradation and conversion on local temperature.

Senior RA, Hill JK, González Del Pliego P, Goode LK, Edwards DP.

Ecol Evol. 2017 Aug 30;7(19):7897-7908. doi: 10.1002/ece3.3262. eCollection 2017 Oct.


The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent.

Acharya KD, Nettles SA, Sellers KJ, Im DD, Harling M, Pattanayak C, Vardar-Ulu D, Lichti CF, Huang S, Edwards DP, Srivastava DP, Denner L, Tetel MJ.

eNeuro. 2017 Sep 20;4(5). pii: ENEURO.0272-17.2017. doi: 10.1523/ENEURO.0272-17.2017. eCollection 2017 Sep-Oct.


Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer.

Haricharan S, Punturi N, Singh P, Holloway KR, Anurag M, Schmelz J, Schmidt C, Lei JT, Suman V, Hunt K, Olson JA Jr, Hoog J, Li S, Huang S, Edwards DP, Kavuri SM, Bainbridge MN, Ma CX, Ellis MJ.

Cancer Discov. 2017 Oct;7(10):1168-1183. doi: 10.1158/2159-8290.CD-16-1179. Epub 2017 Aug 11.


The effects of restoring logged tropical forests on avian phylogenetic and functional diversity.

Cosset CCP, Edwards DP.

Ecol Appl. 2017 Sep;27(6):1932-1945. doi: 10.1002/eap.1578. Epub 2017 Jul 26.


NEMO, a Transcriptional Target of Estrogen and Progesterone, Is Linked to Tumor Suppressor PML in Breast Cancer.

Elsarraj HS, Valdez KE, Hong Y, Grimm SL, Ricci LR, Fan F, Tawfik O, May L, Cusick T, Inciardi M, Redick M, Gatewood J, Winblad O, Hilsenbeck S, Edwards DP, Hagan CR, Godwin AK, Fabian C, Behbod F.

Cancer Res. 2017 Jul 15;77(14):3802-3813. doi: 10.1158/0008-5472.CAN-16-2794. Epub 2017 May 17.


Climate change mitigation: potential benefits and pitfalls of enhanced rock weathering in tropical agriculture.

Edwards DP, Lim F, James RH, Pearce CR, Scholes J, Freckleton RP, Beerling DJ.

Biol Lett. 2017 Apr;13(4). pii: 20160715. doi: 10.1098/rsbl.2016.0715. Review.


FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer.

Fu X, Jeselsohn R, Pereira R, Hollingsworth EF, Creighton CJ, Li F, Shea M, Nardone A, De Angelis C, Heiser LM, Anur P, Wang N, Grasso CS, Spellman PT, Griffith OL, Tsimelzon A, Gutierrez C, Huang S, Edwards DP, Trivedi MV, Rimawi MF, Lopez-Terrada D, Hilsenbeck SG, Gray JW, Brown M, Osborne CK, Schiff R.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6600-E6609. Epub 2016 Oct 6.


Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers.

Kim JA, Tan Y, Wang X, Cao X, Veeraraghavan J, Liang Y, Edwards DP, Huang S, Pan X, Li K, Schiff R, Wang XS.

Nat Commun. 2016 Oct 3;7:12991. doi: 10.1038/ncomms12991.


Denial of long-term issues with agriculture on tropical peatlands will have devastating consequences.

Wijedasa LS, Jauhiainen J, Könönen M, Lampela M, Vasander H, Leblanc MC, Evers S, Smith TE, Yule CM, Varkkey H, Lupascu M, Parish F, Singleton I, Clements GR, Aziz SA, Harrison ME, Cheyne S, Anshari GZ, Meijaard E, Goldstein JE, Waldron S, Hergoualc'h K, Dommain R, Frolking S, Evans CD, Posa MR, Glaser PH, Suryadiputra N, Lubis R, Santika T, Padfield R, Kurnianto S, Hadisiswoyo P, Lim TW, Page SE, Gauci V, Van Der Meer PJ, Buckland H, Garnier F, Samuel MK, Choo LN, O'Reilly P, Warren M, Suksuwan S, Sumarga E, Jain A, Laurance WF, Couwenberg J, Joosten H, Vernimmen R, Hooijer A, Malins C, Cochrane MA, Perumal B, Siegert F, Peh KS, Comeau LP, Verchot L, Harvey CF, Cobb A, Jaafar Z, Wösten H, Manuri S, Müller M, Giesen W, Phelps J, Yong DL, Silvius M, Wedeux BM, Hoyt A, Osaki M, Hirano T, Takahashi H, Kohyama TS, Haraguchi A, Nugroho NP, Coomes DA, Quoi LP, Dohong A, Gunawan H, Gaveau DL, Langner A, Lim FK, Edwards DP, Giam X, Van Der Werf G, Carmenta R, Verwer CC, Gibson L, Gandois L, Graham LL, Regalino J, Wich SA, Rieley J, Kettridge N, Brown C, Pirard R, Moore S, Capilla BR, Ballhorn U, Ho HC, Hoscilo A, Lohberger S, Evans TA, Yulianti N, Blackham G, Onrizal, Husson S, Murdiyarso D, Pangala S, Cole LE, Tacconi L, Segah H, Tonoto P, Lee JS, Schmilewski G, Wulffraat S, Putra EI, Cattau ME, Clymo RS, Morrison R, Mujahid A, Miettinen J, Liew SC, Valpola S, Wilson D, D'Arcy L, Gerding M, Sundari S, Thornton SA, Kalisz B, Chapman SJ, Su AS, Basuki I, Itoh M, Traeholt C, Sloan S, Sayok AK, Andersen R.

Glob Chang Biol. 2017 Mar;23(3):977-982. doi: 10.1111/gcb.13516. Epub 2017 Jan 10. No abstract available.


Generation of an in vitro 3D PDAC stroma rich spheroid model.

Ware MJ, Keshishian V, Law JJ, Ho JC, Favela CA, Rees P, Smith B, Mohammad S, Hwang RF, Rajapakshe K, Coarfa C, Huang S, Edwards DP, Corr SJ, Godin B, Curley SA.

Biomaterials. 2016 Nov;108:129-42. doi: 10.1016/j.biomaterials.2016.08.041. Epub 2016 Sep 2.


Progesterone Receptor Signaling Mechanisms.

Grimm SL, Hartig SM, Edwards DP.

J Mol Biol. 2016 Sep 25;428(19):3831-49. doi: 10.1016/j.jmb.2016.06.020. Epub 2016 Jul 2. Review.


Conservation: The rainforest's 'do not disturb' signs.

Edwards DP.

Nature. 2016 Jul 7;535(7610):44-5. Epub 2016 Jun 29. No abstract available.


Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.

Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH.

Nat Cell Biol. 2016 Jun 28;18(7):822. doi: 10.1038/ncb3379. No abstract available.


The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.

Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B.

Prostate. 2016 Oct;76(14):1271-84. doi: 10.1002/pros.23213. Epub 2016 Jun 8.


Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer.

Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, Stossi F, Li H, Samanta S, Cao X, Tsouko E, Huang S, Frigo DE, Chan L, Edwards DP, Kaipparettu BA, Mitsiades N, Weigel NL, Mancini M, McGuire SE, Mehra R, Ittmann MM, Chinnaiyan AM, Putluri N, Palapattu GS, Michailidis G, Sreekumar A.

Nat Commun. 2016 May 19;7:11612. doi: 10.1038/ncomms11612.


Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.

Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH.

Nat Cell Biol. 2016 Jun;18(6):632-44. doi: 10.1038/ncb3355. Epub 2016 May 16. Erratum in: Nat Cell Biol. 2016 Jun 28;18(7):822.


Sparse Data Necessitate Explicit Treatment of Beta-Diversity: A Reply to Bush et al.

Socolar JB, Gilroy JJ, Kunin WE, Edwards DP.

Trends Ecol Evol. 2016 May;31(5):338-339. doi: 10.1016/j.tree.2016.02.019. Epub 2016 Mar 18. No abstract available.


The impact of tropical forest logging and oil palm agriculture on the soil microbiome.

Tripathi BM, Edwards DP, Mendes LW, Kim M, Dong K, Kim H, Adams JM.

Mol Ecol. 2016 May;25(10):2244-57. doi: 10.1111/mec.13620. Epub 2016 Apr 20.


Selective logging in tropical forests decreases the robustness of liana-tree interaction networks to the loss of host tree species.

Magrach A, Senior RA, Rogers A, Nurdin D, Benedick S, Laurance WF, Santamaria L, Edwards DP.

Proc Biol Sci. 2016 Mar 16;283(1826):20153008. doi: 10.1098/rspb.2015.3008.


How Should Beta-Diversity Inform Biodiversity Conservation?

Socolar JB, Gilroy JJ, Kunin WE, Edwards DP.

Trends Ecol Evol. 2016 Jan;31(1):67-80. doi: 10.1016/j.tree.2015.11.005. Epub 2015 Dec 14. Review.


Preventing tropical mining disasters.

Edwards DP, Laurance WF.

Science. 2015 Dec 18;350(6267):1482. doi: 10.1126/science.350.6267.1482-c. No abstract available.


Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK.

Treviño LS, Bolt MJ, Grimm SL, Edwards DP, Mancini MA, Weigel NL.

Mol Endocrinol. 2016 Feb;30(2):158-72. doi: 10.1210/me.2015-1144. Epub 2015 Dec 11.


Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer.

Holdman XB, Welte T, Rajapakshe K, Pond A, Coarfa C, Mo Q, Huang S, Hilsenbeck SG, Edwards DP, Zhang X, Rosen JM.

Breast Cancer Res. 2015 Nov 18;17:141. doi: 10.1186/s13058-015-0649-1.


Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns.

Szafran AT, Mancini MG, Nickerson JA, Edwards DP, Mancini MA.

Methods. 2016 Mar 1;96:75-84. doi: 10.1016/j.ymeth.2015.10.021. Epub 2015 Oct 30.

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