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Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury.

Rangon CM, Schang AL, Van Steenwinckel J, Schwendimann L, Lebon S, Fu T, Chen L, Beneton V, Journiac N, Young-Ten P, Bourgeois T, Maze J, Matrot B, Baburamani AA, Supramaniam V, Mallard C, Trottet L, Edwards AD, Hagberg H, Fleiss B, Li J, Chuang TT, Gressens P.

Brain Behav Immun. 2018 Sep 12. pii: S0889-1591(18)30295-2. doi: 10.1016/j.bbi.2018.09.017. [Epub ahead of print]


High potency of lipid conjugated TLR7 agonist requires nanoparticulate or liposomal formulation.

Gadd AJR, Castelletto V, Kabova E, Shankland K, Perrie Y, Hamley I, Cobb AJA, Greco F, Edwards AD.

Eur J Pharm Sci. 2018 Oct 15;123:268-276. doi: 10.1016/j.ejps.2018.07.048. Epub 2018 Jul 24.


Mixing is required for uniform reconstitution of filter-dried protein antigens in a single-injection vaccine formulation.

Thangsupanimitchai N, Edwards AD.

Vaccine. 2018 Aug 9;36(33):5058-5064. doi: 10.1016/j.vaccine.2018.07.001. Epub 2018 Jul 10.


Hypothermia for perinatal asphyxia: trial-based resource use and costs at 6-7 years.

Rivero-Arias O, Eddama O, Azzopardi D, Edwards AD, Strohm B, Campbell H.

Arch Dis Child Fetal Neonatal Ed. 2018 Jul 11. pii: fetalneonatal-2017-314685. doi: 10.1136/archdischild-2017-314685. [Epub ahead of print]


Somatotopic Mapping of the Developing Sensorimotor Cortex in the Preterm Human Brain.

Dall'Orso S, Steinweg J, Allievi AG, Edwards AD, Burdet E, Arichi T.

Cereb Cortex. 2018 Jul 1;28(7):2507-2515. doi: 10.1093/cercor/bhy050.


Construction of a neonatal cortical surface atlas using Multimodal Surface Matching in the Developing Human Connectome Project.

Bozek J, Makropoulos A, Schuh A, Fitzgibbon S, Wright R, Glasser MF, Coalson TS, O'Muircheartaigh J, Hutter J, Price AN, Cordero-Grande L, Teixeira RPAG, Hughes E, Tusor N, Baruteau KP, Rutherford MA, Edwards AD, Hajnal JV, Smith SM, Rueckert D, Jenkinson M, Robinson EC.

Neuroimage. 2018 Oct 1;179:11-29. doi: 10.1016/j.neuroimage.2018.06.018. Epub 2018 Jun 14.


Automated processing pipeline for neonatal diffusion MRI in the developing Human Connectome Project.

Bastiani M, Andersson JLR, Cordero-Grande L, Murgasova M, Hutter J, Price AN, Makropoulos A, Fitzgibbon SP, Hughes E, Rueckert D, Victor S, Rutherford M, Edwards AD, Smith SM, Tournier JD, Hajnal JV, Jbabdi S, Sotiropoulos SN.

Neuroimage. 2018 May 28. pii: S1053-8119(18)30488-9. doi: 10.1016/j.neuroimage.2018.05.064. [Epub ahead of print]


Different patterns of cortical maturation before and after 38 weeks gestational age demonstrated by diffusion MRI in vivo.

Batalle D, O'Muircheartaigh J, Makropoulos A, Kelly CJ, Dimitrova R, Hughes EJ, Hajnal JV, Zhang H, Alexander DC, Edwards AD, Counsell SJ.

Neuroimage. 2018 May 23. pii: S1053-8119(18)30460-9. doi: 10.1016/j.neuroimage.2018.05.046. [Epub ahead of print]


A lateral-to-mesial organization of human ventral visual cortex at birth.

Barttfeld P, Abboud S, Lagercrantz H, Adén U, Padilla N, Edwards AD, Cohen L, Sigman M, Dehaene S, Dehaene-Lambertz G.

Brain Struct Funct. 2018 May 11. doi: 10.1007/s00429-018-1676-3. [Epub ahead of print]


UC-1V150, a potent TLR7 agonist capable of activating macrophages and potentiating mAb-mediated target cell deletion.

Dahal LN, Gadd A, Edwards AD, Cragg MS, Beers SA.

Scand J Immunol. 2018 Jun;87(6):e12666. doi: 10.1111/sji.12666. Epub 2018 May 6.


Hypothermia for perinatal asphyxia: trial-based quality of life at 6-7 years.

Campbell H, Eddama O, Azzopardi D, Edwards AD, Strohm B, Rivero-Arias O.

Arch Dis Child. 2018 Jul;103(7):654-659. doi: 10.1136/archdischild-2017-313733. Epub 2018 Mar 6.


Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND).

Stolp HB, Ball G, So PW, Tournier JD, Jones M, Thornton C, Edwards AD.

Sci Rep. 2018 Mar 5;8(1):4011. doi: 10.1038/s41598-018-22295-9.


The developing human connectome project: A minimal processing pipeline for neonatal cortical surface reconstruction.

Makropoulos A, Robinson EC, Schuh A, Wright R, Fitzgibbon S, Bozek J, Counsell SJ, Steinweg J, Vecchiato K, Passerat-Palmbach J, Lenz G, Mortari F, Tenev T, Duff EP, Bastiani M, Cordero-Grande L, Hughes E, Tusor N, Tournier JD, Hutter J, Price AN, Teixeira RPAG, Murgasova M, Victor S, Kelly C, Rutherford MA, Smith SM, Edwards AD, Hajnal JV, Jenkinson M, Rueckert D.

Neuroimage. 2018 Jun;173:88-112. doi: 10.1016/j.neuroimage.2018.01.054. Epub 2018 Jan 31.


Machine learning shows association between genetic variability in PPARG and cerebral connectivity in preterm infants.

Krishnan ML, Wang Z, Aljabar P, Ball G, Mirza G, Saxena A, Counsell SJ, Hajnal JV, Montana G, Edwards AD.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13744-13749. doi: 10.1073/pnas.1704907114. Epub 2017 Dec 11.


Impaired development of the cerebral cortex in infants with congenital heart disease is correlated to reduced cerebral oxygen delivery.

Kelly CJ, Makropoulos A, Cordero-Grande L, Hutter J, Price A, Hughes E, Murgasova M, Teixeira RPAG, Steinweg JK, Kulkarni S, Rahman L, Zhang H, Alexander DC, Pushparajah K, Rueckert D, Hajnal JV, Simpson J, Edwards AD, Rutherford MA, Counsell SJ.

Sci Rep. 2017 Nov 8;7(1):15088. doi: 10.1038/s41598-017-14939-z.


Annual Research Review: Not just a small adult brain: understanding later neurodevelopment through imaging the neonatal brain.

Batalle D, Edwards AD, O'Muircheartaigh J.

J Child Psychol Psychiatry. 2018 Apr;59(4):350-371. doi: 10.1111/jcpp.12838. Epub 2017 Nov 3. Review.


Multimodal surface matching with higher-order smoothness constraints.

Robinson EC, Garcia K, Glasser MF, Chen Z, Coalson TS, Makropoulos A, Bozek J, Wright R, Schuh A, Webster M, Hutter J, Price A, Cordero Grande L, Hughes E, Tusor N, Bayly PV, Van Essen DC, Smith SM, Edwards AD, Hajnal J, Jenkinson M, Glocker B, Rueckert D.

Neuroimage. 2018 Feb 15;167:453-465. doi: 10.1016/j.neuroimage.2017.10.037. Epub 2017 Oct 31.


Punctate White Matter Lesions Associated With Altered Brain Development And Adverse Motor Outcome In Preterm Infants.

Tusor N, Benders MJ, Counsell SJ, Nongena P, Ederies MA, Falconer S, Chew A, Gonzalez-Cinca N, Hajnal JV, Gangadharan S, Chatzi V, Kersbergen KJ, Kennea N, Azzopardi DV, Edwards AD.

Sci Rep. 2017 Oct 16;7(1):13250. doi: 10.1038/s41598-017-13753-x.


Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation.

Edwards AD, Redshaw ME, Kennea N, Rivero-Arias O, Gonzales-Cinca N, Nongena P, Ederies M, Falconer S, Chew A, Omar O, Hardy P, Harvey ME, Eddama O, Hayward N, Wurie J, Azzopardi D, Rutherford MA, Counsell S; ePrime Investigators.

Arch Dis Child Fetal Neonatal Ed. 2018 Jan;103(1):F15-F21. doi: 10.1136/archdischild-2017-313102. Epub 2017 Oct 7.


Localization of spontaneous bursting neuronal activity in the preterm human brain with simultaneous EEG-fMRI.

Arichi T, Whitehead K, Barone G, Pressler R, Padormo F, Edwards AD, Fabrizi L.

Elife. 2017 Sep 12;6. pii: e27814. doi: 10.7554/eLife.27814.


Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants.

Krishnan ML, Van Steenwinckel J, Schang AL, Yan J, Arnadottir J, Le Charpentier T, Csaba Z, Dournaud P, Cipriani S, Auvynet C, Titomanlio L, Pansiot J, Ball G, Boardman JP, Walley AJ, Saxena A, Mirza G, Fleiss B, Edwards AD, Petretto E, Gressens P.

Nat Commun. 2017 Sep 5;8(1):428. doi: 10.1038/s41467-017-00422-w.


Multimodal image analysis of clinical influences on preterm brain development.

Ball G, Aljabar P, Nongena P, Kennea N, Gonzalez-Cinca N, Falconer S, Chew ATM, Harper N, Wurie J, Rutherford MA, Counsell SJ, Edwards AD.

Ann Neurol. 2017 Aug;82(2):233-246. doi: 10.1002/ana.24995. Epub 2017 Aug 19.


Time-efficient and flexible design of optimized multishell HARDI diffusion.

Hutter J, Tournier JD, Price AN, Cordero-Grande L, Hughes EJ, Malik S, Steinweg J, Bastiani M, Sotiropoulos SN, Jbabdi S, Andersson J, Edwards AD, Hajnal JV.

Magn Reson Med. 2018 Mar;79(3):1276-1292. doi: 10.1002/mrm.26765. Epub 2017 May 30.


Language ability in preterm children is associated with arcuate fasciculi microstructure at term.

Salvan P, Tournier JD, Batalle D, Falconer S, Chew A, Kennea N, Aljabar P, Dehaene-Lambertz G, Arichi T, Edwards AD, Counsell SJ.

Hum Brain Mapp. 2017 Aug;38(8):3836-3847. doi: 10.1002/hbm.23632. Epub 2017 May 4.


A tract-specific approach to assessing white matter in preterm infants.

Pecheva D, Yushkevich P, Batalle D, Hughes E, Aljabar P, Wurie J, Hajnal JV, Edwards AD, Alexander DC, Counsell SJ, Zhang H.

Neuroimage. 2017 Aug 15;157:675-694. doi: 10.1016/j.neuroimage.2017.04.057. Epub 2017 Apr 27.


Covalent immobilisation of antibodies in Teflon-FEP microfluidic devices for the sensitive quantification of clinically relevant protein biomarkers.

Pivetal J, Pereira FM, Barbosa AI, Castanheira AP, Reis NM, Edwards AD.

Analyst. 2017 Mar 13;142(6):959-968. doi: 10.1039/c6an02622b.


Early development of structural networks and the impact of prematurity on brain connectivity.

Batalle D, Hughes EJ, Zhang H, Tournier JD, Tusor N, Aljabar P, Wali L, Alexander DC, Hajnal JV, Nosarti C, Edwards AD, Counsell SJ.

Neuroimage. 2017 Apr 1;149:379-392. doi: 10.1016/j.neuroimage.2017.01.065. Epub 2017 Jan 30.


New mothers' experiences of the urban environment with their preterm infants involve complex social, emotional and psychological processes.

Gullino S, Kaiser A, Khan H, Phillips A, Elwin A, Edwards AD.

Acta Paediatr. 2017 Mar;106(3):405-410. doi: 10.1111/apa.13715. Epub 2017 Jan 26.


A dedicated neonatal brain imaging system.

Hughes EJ, Winchman T, Padormo F, Teixeira R, Wurie J, Sharma M, Fox M, Hutter J, Cordero-Grande L, Price AN, Allsop J, Bueno-Conde J, Tusor N, Arichi T, Edwards AD, Rutherford MA, Counsell SJ, Hajnal JV.

Magn Reson Med. 2017 Aug;78(2):794-804. doi: 10.1002/mrm.26462. Epub 2016 Sep 19.


Cerebello-cerebral connectivity in the developing brain.

Pieterman K, Batalle D, Dudink J, Tournier JD, Hughes EJ, Barnett M, Benders MJ, Edwards AD, Hoebeek FE, Counsell SJ.

Brain Struct Funct. 2017 May;222(4):1625-1634. doi: 10.1007/s00429-016-1296-8. Epub 2016 Aug 29.


Involving Older Adults in the Technology Design Process: A Case Study on Mobility and Wellbeing in the Built Environment.

Swallow D, Petrie H, Power C, Lewis A, Edwards AD.

Stud Health Technol Inform. 2016;229:615-23.


Hemodynamic response to burst-suppressed and discontinuous electroencephalography activity in infants with hypoxic ischemic encephalopathy.

Chalia M, Lee CW, Dempsey LA, Edwards AD, Singh H, Michell AW, Everdell NL, Hill RW, Hebden JC, Austin T, Cooper RJ.

Neurophotonics. 2016 Jul;3(3):031408. doi: 10.1117/1.NPh.3.3.031408. Epub 2016 May 2.


Characterising brain network topologies: A dynamic analysis approach using heat kernels.

Chung AW, Schirmer MD, Krishnan ML, Ball G, Aljabar P, Edwards AD, Montana G.

Neuroimage. 2016 Nov 1;141:490-501. doi: 10.1016/j.neuroimage.2016.07.006. Epub 2016 Jul 14.


Lab on a stick: multi-analyte cellular assays in a microfluidic dipstick.

Reis NM, Pivetal J, Loo-Zazueta AL, Barros JM, Edwards AD.

Lab Chip. 2016 Aug 7;16(15):2891-9. doi: 10.1039/c6lc00332j. Epub 2016 Jul 4.


Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants.

Krishnan ML, Wang Z, Silver M, Boardman JP, Ball G, Counsell SJ, Walley AJ, Montana G, Edwards AD.

Brain Behav. 2016 Apr 2;6(7):e00434. doi: 10.1002/brb3.434. eCollection 2016 Jul.


Evaluating and optimizing oral formulations of live bacterial vaccines using a gastro-small intestine model.

de Barros JM, Costabile A, Charalampopoulos D, Khutoryanskiy VV, Edwards AD.

Eur J Pharm Biopharm. 2016 May;102:115-22. doi: 10.1016/j.ejpb.2016.03.010. Epub 2016 Mar 8.


Reinforcement of the Brain's Rich-Club Architecture Following Early Neurodevelopmental Disruption Caused by Very Preterm Birth.

Karolis VR, Froudist-Walsh S, Brittain PJ, Kroll J, Ball G, Edwards AD, Dell'Acqua F, Williams SC, Murray RM, Nosarti C.

Cereb Cortex. 2016 Mar;26(3):1322-35. doi: 10.1093/cercor/bhv305. Epub 2016 Jan 7.


Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial.

Azzopardi D, Robertson NJ, Bainbridge A, Cady E, Charles-Edwards G, Deierl A, Fagiolo G, Franks NP, Griffiths J, Hajnal J, Juszczak E, Kapetanakis B, Linsell L, Maze M, Omar O, Strohm B, Tusor N, Edwards AD.

Lancet Neurol. 2016 Feb;15(2):145-153. doi: 10.1016/S1474-4422(15)00347-6. Epub 2015 Dec 19.


Characteristics of Two-Year College Students on the Autism Spectrum and Their Support Services Experiences.

Roux AM, Shattuck PT, Rast JE, Rava JA, Edwards AD, Wei X, McCracken M, Yu JW.

Autism Res Treat. 2015;2015:391693. doi: 10.1155/2015/391693. Epub 2015 Nov 15.


Regional growth and atlasing of the developing human brain.

Makropoulos A, Aljabar P, Wright R, Hüning B, Merchant N, Arichi T, Tusor N, Hajnal JV, Edwards AD, Counsell SJ, Rueckert D.

Neuroimage. 2016 Jan 15;125:456-478. doi: 10.1016/j.neuroimage.2015.10.047. Epub 2015 Oct 21.


Maturation of Sensori-Motor Functional Responses in the Preterm Brain.

Allievi AG, Arichi T, Tusor N, Kimpton J, Arulkumaran S, Counsell SJ, Edwards AD, Burdet E.

Cereb Cortex. 2016 Jan;26(1):402-413. doi: 10.1093/cercor/bhv203. Epub 2015 Oct 21.


Machine-learning to characterise neonatal functional connectivity in the preterm brain.

Ball G, Aljabar P, Arichi T, Tusor N, Cox D, Merchant N, Nongena P, Hajnal JV, Edwards AD, Counsell SJ.

Neuroimage. 2016 Jan 1;124(Pt A):267-275. doi: 10.1016/j.neuroimage.2015.08.055. Epub 2015 Sep 2.


Implementation and Evaluation of a School-Based Human Papillomavirus Vaccination Program in Rural Kentucky.

Vanderpool RC, Breheny PJ, Tiller PA, Huckelby CA, Edwards AD, Upchurch KD, Phillips CA, Weyman CF.

Am J Prev Med. 2015 Aug;49(2):317-23. doi: 10.1016/j.amepre.2015.05.001.


Enteric coated spheres produced by extrusion/spheronization provide effective gastric protection and efficient release of live therapeutic bacteria.

de Barros JM, Lechner T, Charalampopoulos D, Khutoryanskiy VV, Edwards AD.

Int J Pharm. 2015 Sep 30;493(1-2):483-94. doi: 10.1016/j.ijpharm.2015.06.051. Epub 2015 Jul 15.


Targeted Activation of Toll-Like Receptors: Conjugation of a Toll-Like Receptor 7 Agonist to a Monoclonal Antibody Maintains Antigen Binding and Specificity.

Gadd AJ, Greco F, Cobb AJ, Edwards AD.

Bioconjug Chem. 2015 Aug 19;26(8):1743-52. doi: 10.1021/acs.bioconjchem.5b00302. Epub 2015 Jul 16.


Multiplexed femtomolar quantitation of human cytokines in a fluoropolymer microcapillary film.

Castanheira AP, Barbosa AI, Edwards AD, Reis NM.

Analyst. 2015 Aug 21;140(16):5609-18. doi: 10.1039/c5an00238a.


Specialization and integration of functional thalamocortical connectivity in the human infant.

Toulmin H, Beckmann CF, O'Muircheartaigh J, Ball G, Nongena P, Makropoulos A, Ederies A, Counsell SJ, Kennea N, Arichi T, Tusor N, Rutherford MA, Azzopardi D, Gonzalez-Cinca N, Hajnal JV, Edwards AD.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6485-90. doi: 10.1073/pnas.1422638112. Epub 2015 May 4.


Portable smartphone quantitation of prostate specific antigen (PSA) in a fluoropolymer microfluidic device.

Barbosa AI, Gehlot P, Sidapra K, Edwards AD, Reis NM.

Biosens Bioelectron. 2015 Aug 15;70:5-14. doi: 10.1016/j.bios.2015.03.006. Epub 2015 Mar 5.


Thalamocortical Connectivity Predicts Cognition in Children Born Preterm.

Ball G, Pazderova L, Chew A, Tusor N, Merchant N, Arichi T, Allsop JM, Cowan FM, Edwards AD, Counsell SJ.

Cereb Cortex. 2015 Nov;25(11):4310-8. doi: 10.1093/cercor/bhu331. Epub 2015 Jan 16.


Birth asphyxia: 100 years of progress.

Tusor N, Edwards AD.

J Pediatr. 2014 Dec;165(6):1081-3. doi: 10.1016/j.jpeds.2014.08.051. Epub 2014 Oct 1. No abstract available.


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