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Items: 1 to 50 of 862

1.

Shaping the future of migraine targeting Calcitonin-Gene-Related-Peptide with the Disease-Modifying Migraine Drugs (DMMDs).

Martelletti P, Edvinsson L, Ashina M.

J Headache Pain. 2019 May 23;20(1):60. doi: 10.1186/s10194-019-1009-9. No abstract available.

2.

Exploration of purinergic receptors as potential anti-migraine targets using established pre-clinical migraine models.

Haanes KA, Labastida-Ramírez A, Blixt FW, Rubio-Beltrán E, Dirven CM, Danser AH, Edvinsson L, MaassenVanDenBrink A.

Cephalalgia. 2019 May 19:333102419851810. doi: 10.1177/0333102419851810. [Epub ahead of print]

PMID:
31104506
3.

The changing faces of migraine.

Martelletti P, Ashina M, Edvinsson L.

J Headache Pain. 2019 May 10;20(1):52. doi: 10.1186/s10194-019-1006-z. No abstract available.

4.

Pathophysiological Mechanisms in Migraine and the Identification of New Therapeutic Targets.

Haanes KA, Edvinsson L.

CNS Drugs. 2019 Jun;33(6):525-537. doi: 10.1007/s40263-019-00630-6.

PMID:
30989485
5.

MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats.

Christensen ST, Johansson SE, Radziwon-Balicka A, Warfvinge K, Haanes KA, Edvinsson L.

PLoS One. 2019 Apr 12;14(4):e0215398. doi: 10.1371/journal.pone.0215398. eCollection 2019.

6.

Some aspects on the pathophysiology of migraine and a review of device therapies for migraine and cluster headache.

Rapoport AM, Edvinsson L.

Neurol Sci. 2019 May;40(Suppl 1):75-80. doi: 10.1007/s10072-019-03828-0. Review.

PMID:
30906962
7.

Dr James Lance, Professor of Neurology in Sydney, Australia, died on 20 February 2019, age 92.

Edvinsson L, Evers S, Goadsby PJ.

Cephalalgia. 2019 Apr;39(5):681-682. doi: 10.1177/0333102419840639. Epub 2019 Mar 21. No abstract available.

PMID:
30897943
8.

Discovery of CGRP in relation to migraine.

Edvinsson L, Goadsby PJ.

Cephalalgia. 2019 Mar;39(3):331-332. doi: 10.1177/0333102418779544. No abstract available.

PMID:
30827155
9.

Role of CGRP in Migraine.

Edvinsson L.

Handb Exp Pharmacol. 2019 Feb 7. doi: 10.1007/164_2018_201. [Epub ahead of print]

PMID:
30725283
10.

Vascular pathology of large cerebral arteries in experimental subarachnoid hemorrhage: Vasoconstriction, functional CGRP depletion and maintained CGRP sensitivity.

Johansson SE, Abdolalizadeh B, Sheykhzade M, Edvinsson L, Sams A.

Eur J Pharmacol. 2019 Mar 5;846:109-118. doi: 10.1016/j.ejphar.2019.01.007. Epub 2019 Jan 14.

PMID:
30653947
11.

PAC1 receptor mRNA and protein distribution in rat and human trigeminal and sphenopalatine ganglia, spinal trigeminal nucleus and in dura mater.

Hensley K, Pretorius J, Chan B, Page K, Liu H, Choi C, Shi D, Xu C, Edvinsson L, Miller S.

Cephalalgia. 2019 Jun;39(7):827-840. doi: 10.1177/0333102418821621. Epub 2018 Dec 24.

PMID:
30582714
12.

CGRP Antibodies as Prophylaxis in Migraine.

Edvinsson L.

Cell. 2018 Dec 13;175(7):1719. doi: 10.1016/j.cell.2018.11.049.

PMID:
30550780
13.

Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion.

Kristiansen SB, Skovsted GF, Berchtold LA, Radziwon-Balicka A, Dreisig K, Edvinsson L, Sheykhzade M, Haanes KA.

Scand Cardiovasc J. 2018 Dec;52(6):340-343. doi: 10.1080/14017431.2018.1552793. Epub 2019 Jan 7.

PMID:
30481075
14.

MEK/ERK/1/2 sensitive vascular changes coincide with retinal functional deficit, following transient ophthalmic artery occlusion.

Blixt FW, Haanes KA, Ohlsson L, Dreisig K, Fedulov V, Warfvinge K, Edvinsson L.

Exp Eye Res. 2019 Feb;179:142-149. doi: 10.1016/j.exer.2018.11.003. Epub 2018 Nov 12.

PMID:
30439349
15.

Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans.

Frederiksen SD, Warfvinge K, Ohlsson L, Edvinsson L.

Neuroscience. 2018 Nov 21;393:319-332. doi: 10.1016/j.neuroscience.2018.10.004. Epub 2018 Oct 15.

PMID:
30336190
16.

Smoking and Endothelial Dysfunction.

Golbidi S, Edvinsson L, Laher I.

Curr Vasc Pharmacol. 2018 Sep 13. doi: 10.2174/1573403X14666180913120015. [Epub ahead of print]

PMID:
30210003
17.

Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries.

Ohlsson L, Kronvall E, Stratton J, Edvinsson L.

J Headache Pain. 2018 Aug 14;19(1):66. doi: 10.1186/s10194-018-0905-8.

18.

PACAP38 and PAC1 receptor blockade: a new target for headache?

Rubio-Beltrán E, Correnti E, Deen M, Kamm K, Kelderman T, Papetti L, Vigneri S, MaassenVanDenBrink A, Edvinsson L; European Headache Federation School of Advanced Studies (EHF-SAS).

J Headache Pain. 2018 Aug 7;19(1):64. doi: 10.1186/s10194-018-0893-8. Review.

19.

Vancouver Declaration on Global Headache Patient Advocacy 2018.

Dodick D, Edvinsson L, Makino T, Grisold W, Sakai F, Jensen R, Balch A, Ruiz de la Torre E, Henscheid-Lorenz D, Craven A, Ashina M.

Cephalalgia. 2018 Nov;38(13):1899-1909. doi: 10.1177/0333102418781644. Epub 2018 Jun 8.

PMID:
29882695
20.

The therapeutic impact of new migraine discoveries.

Vécsei L, Lukács M, Tajti J, Fülöp F, Toldi J, Edvinsson L.

Curr Med Chem. 2018 May 29. doi: 10.2174/0929867325666180530114534. [Epub ahead of print]

PMID:
29848264
21.

The CGRP Pathway in Migraine as a Viable Target for Therapies.

Edvinsson L.

Headache. 2018 May;58 Suppl 1:33-47. doi: 10.1111/head.13305.

PMID:
29697153
22.

CGRP as the target of new migraine therapies - successful translation from bench to clinic.

Edvinsson L, Haanes KA, Warfvinge K, Krause DN.

Nat Rev Neurol. 2018 Jun;14(6):338-350. doi: 10.1038/s41582-018-0003-1. Review.

PMID:
29691490
23.

Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX.

Sheykhzade M, Abdolalizadeh B, Koole C, Pickering DS, Dreisig K, Johansson SE, Abboud BK, Dreier R, Berg JO, Jeppesen JL, Sexton PM, Edvinsson L, Wootten D, Sams A.

Eur J Pharmacol. 2018 Jun 15;829:85-92. doi: 10.1016/j.ejphar.2018.04.007. Epub 2018 Apr 10.

PMID:
29653090
24.

PACAP and its role in primary headaches.

Edvinsson L, Tajti J, Szalárdy L, Vécsei L.

J Headache Pain. 2018 Mar 9;19(1):21. doi: 10.1186/s10194-018-0852-4. Review.

25.

Increased endothelin-1-mediated vasoconstriction after organ culture in rat and pig ocular arteries can be suppressed with MEK/ERK1/2 inhibitors.

Blixt FW, Haanes KA, Ohlsson L, Tolstrup Christiansen A, Warfvinge K, Edvinsson L.

Acta Ophthalmol. 2018 Aug;96(5):e619-e625. doi: 10.1111/aos.13651. Epub 2018 Jan 25.

PMID:
29369532
26.

Headache advances in 2017: a new horizon in migraine therapy.

Edvinsson L.

Lancet Neurol. 2018 Jan;17(1):5-6. doi: 10.1016/S1474-4422(17)30415-5. Epub 2017 Dec 16. No abstract available.

PMID:
29263007
27.

Perivascular neurotransmitters: Regulation of cerebral blood flow and role in primary headaches.

Frederiksen SD, Haanes KA, Warfvinge K, Edvinsson L.

J Cereb Blood Flow Metab. 2019 Apr;39(4):610-632. doi: 10.1177/0271678X17747188. Epub 2017 Dec 18.

PMID:
29251523
28.

Contractile Responses in Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion.

Grell AS, Mostajeran M, Edvinsson L, Ansar S.

Pharmacology. 2018;101(3-4):120-132. doi: 10.1159/000481570. Epub 2017 Nov 30.

PMID:
29190633
29.

Cerebrovascular Gene Expression in Spontaneously Hypertensive Rats After Transient Middle Cerebral Artery Occlusion.

Grell AS, Mostajeran M, Frederiksen SD, Edvinsson L, Ansar S.

Neuroscience. 2017 Dec 26;367:219-232. doi: 10.1016/j.neuroscience.2017.10.036. Epub 2017 Nov 2.

PMID:
29102661
30.

A novel multicolor flow-cytometry application for quantitative detection of receptors on vascular smooth muscle cells.

Radziwon-Balicka A, Degn M, Johansson SE, Warfvinge K, Edvinsson L.

PLoS One. 2017 Oct 30;12(10):e0186504. doi: 10.1371/journal.pone.0186504. eCollection 2017.

31.

Acute mitogen-activated protein kinase 1/2 inhibition improves functional recovery and vascular changes after ischaemic stroke in rat-monitored by 9.4 T magnetic resonance imaging.

Mostajeran M, Wetterling F, Blixt FW, Edvinsson L, Ansar S.

Acta Physiol (Oxf). 2018 May;223(1):e12985. doi: 10.1111/apha.12985. Epub 2017 Nov 12.

PMID:
29055086
32.

Board Walk - October 2017.

Edvinsson L.

Cephalalgia. 2017 Oct;37(11):1111-1112. doi: 10.1177/0333102417731659. No abstract available.

PMID:
29039695
33.

Recognizing the role of CGRP and CGRP receptors in migraine and its treatment.

Edvinsson L, Warfvinge K.

Cephalalgia. 2019 Mar;39(3):366-373. doi: 10.1177/0333102417736900. Epub 2017 Oct 11.

PMID:
29020807
34.

CGRP receptor antagonist MK-8825 attenuates cortical spreading depression induced pain behavior.

Filiz A, Tepe N, Eftekhari S, Boran HE, Dilekoz E, Edvinsson L, Bolay H.

Cephalalgia. 2019 Mar;39(3):354-365. doi: 10.1177/0333102417735845. Epub 2017 Oct 3.

PMID:
28971699
35.

Blocking CGRP in migraine patients - a review of pros and cons.

Deen M, Correnti E, Kamm K, Kelderman T, Papetti L, Rubio-Beltrán E, Vigneri S, Edvinsson L, Maassen Van Den Brink A; European Headache Federation School of Advanced Studies (EHF-SAS).

J Headache Pain. 2017 Sep 25;18(1):96. doi: 10.1186/s10194-017-0807-1. Review.

36.

Changes in vasodilation following myocardial ischemia/reperfusion in rats.

Kristiansen SB, Sheykhzade M, Edvinsson L, Haanes KA.

Nitric Oxide. 2017 Nov 1;70:68-75. doi: 10.1016/j.niox.2017.09.002. Epub 2017 Sep 14.

PMID:
28919322
37.

Cerebrovascular gene expression in spontaneously hypertensive rats.

Grell AS, Frederiksen SD, Edvinsson L, Ansar S.

PLoS One. 2017 Sep 7;12(9):e0184233. doi: 10.1371/journal.pone.0184233. eCollection 2017.

38.

Distribution of CGRP and CGRP receptor components in the rat brain.

Warfvinge K, Edvinsson L.

Cephalalgia. 2019 Mar;39(3):342-353. doi: 10.1177/0333102417728873. Epub 2017 Aug 31.

PMID:
28856910
39.

Downregulation of Thromboxane A2 Receptor Occurs Mainly via Nuclear Factor-KappaB Signaling Pathway in Rat Renal Artery.

Zhang Y, Mi M, Xie YH, Wang SW, Edvinsson L, Xu CB.

Adv Pharmacol Sci. 2017;2017:6507048. doi: 10.1155/2017/6507048. Epub 2017 Jul 9.

40.

Endothelin receptor mediated Ca2+ signaling in coronary arteries after experimentally induced ischemia/reperfusion injury in rat.

Kristiansen SB, Haanes KA, Sheykhzade M, Edvinsson L.

J Mol Cell Cardiol. 2017 Oct;111:1-9. doi: 10.1016/j.yjmcc.2017.07.013. Epub 2017 Jul 27.

PMID:
28757442
41.

Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway.

Müller AH, Edwards AVG, Larsen MR, Nielsen J, Warfvinge K, Povlsen GK, Edvinsson L.

J Mol Neurosci. 2017 Aug;62(3-4):380-394. doi: 10.1007/s12031-017-0944-7. Epub 2017 Jul 24.

42.

Migraine, Neurogenic Inflammation, Drug Development - Pharmacochemical Aspects.

Lukacs M, Tajti J, Fulop F, Toldi J, Edvinsson L, Vecsei L.

Curr Med Chem. 2017;24(33):3649-3665. doi: 10.2174/0929867324666170712163437. Review.

PMID:
28707585
43.

Distribution of CGRP and its receptor components CLR and RAMP1 in the rat retina.

Blixt FW, Radziwon-Balicka A, Edvinsson L, Warfvinge K.

Exp Eye Res. 2017 Aug;161:124-131. doi: 10.1016/j.exer.2017.06.002. Epub 2017 Jun 8.

PMID:
28603014
44.
45.

Migraine associated with altitude: results from a population-based study in Nepal.

Linde M, Edvinsson L, Manandhar K, Risal A, Steiner TJ.

Eur J Neurol. 2017 Aug;24(8):1055-1061. doi: 10.1111/ene.13334. Epub 2017 May 29.

46.

The Trigeminovascular Pathway: Role of CGRP and CGRP Receptors in Migraine.

Edvinsson L.

Headache. 2017 May;57 Suppl 2:47-55. doi: 10.1111/head.13081. Review.

PMID:
28485848
47.

Topical dura mater application of CFA induces enhanced expression of c-fos and glutamate in rat trigeminal nucleus caudalis: attenuated by KYNA derivate (SZR72).

Lukács M, Warfvinge K, Tajti J, Fülöp F, Toldi J, Vécsei L, Edvinsson L.

J Headache Pain. 2017 Dec;18(1):39. doi: 10.1186/s10194-017-0746-x. Epub 2017 Mar 23.

48.

Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat.

Skovsted GF, Kruse LS, Berchtold LA, Grell AS, Warfvinge K, Edvinsson L.

PLoS One. 2017 Mar 21;12(3):e0174119. doi: 10.1371/journal.pone.0174119. eCollection 2017.

49.

Binding and functional pharmacological characteristics of gepant-type antagonists in rat brain and mesenteric arteries.

Sheykhzade M, Amandi N, Pla MV, Abdolalizadeh B, Sams A, Warfvinge K, Edvinsson L, Pickering DS.

Vascul Pharmacol. 2017 Mar;90:36-43. doi: 10.1016/j.vph.2017.02.001. Epub 2017 Feb 10.

PMID:
28192258
50.

Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat.

Spray S, Johansson SE, Edwards AV, Larsen MR, Radziwon-Balicka A, Povlsen GK, Edvinsson L.

J Mol Neurosci. 2017 Mar;61(3):396-411. doi: 10.1007/s12031-016-0875-8. Epub 2016 Dec 8.

PMID:
27933490

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