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Items: 1 to 50 of 63

1.

Integration of transcriptomics and antibody-based proteomics for exploration of proteins expressed in specialized tissues.

Sjöstedt E, Sivertsson Å, Hikmet Noraddin F, Katona B, Näsström Å, Vuu J, Kesti D, Oksvold P, Edqvist PH, Olsson I, Uhlén M, Lindskog C.

J Proteome Res. 2018 Oct 1. doi: 10.1021/acs.jproteome.8b00406. [Epub ahead of print]

PMID:
30272454
2.

Affibody-derived drug conjugates: Potent cytotoxic molecules for treatment of HER2 over-expressing tumors.

Altai M, Liu H, Ding H, Mitran B, Edqvist PH, Tolmachev V, Orlova A, Gräslund T.

J Control Release. 2018 Oct 28;288:84-95. doi: 10.1016/j.jconrel.2018.08.040. Epub 2018 Aug 30.

PMID:
30172673
3.

Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity.

Roodakker KR, Alhuseinalkhudhur A, Al-Jaff M, Georganaki M, Zetterling M, Berntsson SG, Danfors T, Strand R, Edqvist PH, Dimberg A, Larsson EM, Smits A.

Eur J Nucl Med Mol Imaging. 2018 Aug 14. doi: 10.1007/s00259-018-4107-z. [Epub ahead of print]

PMID:
30109401
4.

Asparaginase-like protein 1 expression in curettage independently predicts lymph node metastasis in endometrial carcinoma: a multicentre study.

Fonnes T, Trovik J, Edqvist PH, Fasmer KE, Marcickiewicz J, Tingulstad S, Staff AC, Bjørge L, Amant F, Haldorsen IS, Werner H, Akslen LA, Tangen IL, Krakstad C.

BJOG. 2018 Jul 10. doi: 10.1111/1471-0528.15403. [Epub ahead of print]

PMID:
29989298
5.

Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma.

Huvila J, Laajala TD, Edqvist PH, Mardinoglu A, Talve L, Pontén F, Grénman S, Carpén O, Aittokallio T, Auranen A.

Gynecol Oncol. 2018 Apr;149(1):173-180. doi: 10.1016/j.ygyno.2018.02.016. Epub 2018 Mar 2.

PMID:
29486992
6.

Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients.

Niinivirta M, Enblad G, Edqvist PH, Pontén F, Dragomir A, Ullenhag GJ.

J Cancer. 2017 Oct 23;8(19):3975-3983. doi: 10.7150/jca.20889. eCollection 2017.

7.

A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.

Carreras-Puigvert J, Zitnik M, Jemth AS, Carter M, Unterlass JE, Hallström B, Loseva O, Karem Z, Calderón-Montaño JM, Lindskog C, Edqvist PH, Matuszewski DJ, Ait Blal H, Berntsson RPA, Häggblad M, Martens U, Studham M, Lundgren B, Wählby C, Sonnhammer ELL, Lundberg E, Stenmark P, Zupan B, Helleday T.

Nat Commun. 2017 Nov 16;8(1):1541. doi: 10.1038/s41467-017-01642-w.

8.

Targeting tumor cells based on Phosphodiesterase 3A expression.

Nazir M, Senkowski W, Nyberg F, Blom K, Edqvist PH, Jarvius M, Andersson C, Gustafsson MG, Nygren P, Larsson R, Fryknäs M.

Exp Cell Res. 2017 Dec 15;361(2):308-315. doi: 10.1016/j.yexcr.2017.10.032. Epub 2017 Oct 26.

PMID:
29107068
9.

Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions.

Fonnes T, Berg HF, Bredholt T, Edqvist PD, Sortland K, Berg A, Salvesen HB, Akslen LA, Werner HMJ, Trovik J, Tangen IL, Krakstad C.

Gynecol Oncol. 2018 Jan;148(1):197-203. doi: 10.1016/j.ygyno.2017.10.025. Epub 2017 Oct 31.

PMID:
29096882
10.

A pathology atlas of the human cancer transcriptome.

Uhlen M, Zhang C, Lee S, Sjöstedt E, Fagerberg L, Bidkhori G, Benfeitas R, Arif M, Liu Z, Edfors F, Sanli K, von Feilitzen K, Oksvold P, Lundberg E, Hober S, Nilsson P, Mattsson J, Schwenk JM, Brunnström H, Glimelius B, Sjöblom T, Edqvist PH, Djureinovic D, Micke P, Lindskog C, Mardinoglu A, Ponten F.

Science. 2017 Aug 18;357(6352). pii: eaan2507. doi: 10.1126/science.aan2507.

PMID:
28818916
11.

EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model.

Gustafsson H, Kale A, Dasu A, Lund A, Edqvist PH, Roberg K.

Cell Biochem Biophys. 2017 Dec;75(3-4):299-309. doi: 10.1007/s12013-017-0814-5. Epub 2017 Jul 29.

12.

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius B, Melin B, Enblad G, Alafuzoff I, Beskow A, Ahlström H, Bill-Axelson A, Birgisson H, Björ O, Edqvist PH, Hansson T, Helleday T, Hellman P, Henriksson K, Hesselager G, Hultdin M, Häggman M, Höglund M, Jonsson H, Larsson C, Lindman H, Ljuslinder I, Mindus S, Nygren P, Pontén F, Riklund K, Rosenquist R, Sandin F, Schwenk JM, Stenling R, Stålberg K, Stålberg P, Sundström C, Thellenberg Karlsson C, Westermark B, Bergh A, Claesson-Welsh L, Palmqvist R, Sjöblom T.

Acta Oncol. 2018 Feb;57(2):187-194. doi: 10.1080/0284186X.2017.1337926. Epub 2017 Jun 20.

PMID:
28631533
13.

Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression.

Roy A, Attarha S, Weishaupt H, Edqvist PH, Swartling FJ, Bergqvist M, Siebzehnrubl FA, Smits A, Pontén F, Tchougounova E.

Oncotarget. 2017 Apr 11;8(15):24815-24827. doi: 10.18632/oncotarget.15820.

14.

Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence.

Byström S, Fredolini C, Edqvist PH, Nyaiesh EN, Drobin K, Uhlén M, Bergqvist M, Pontén F, Schwenk JM.

Transl Oncol. 2017 Jun;10(3):385-395. doi: 10.1016/j.tranon.2017.03.002. Epub 2017 Apr 20.

15.

Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib.

Niinivirta M, Enblad G, Edqvist PH, Pontén F, Dragomir A, Ullenhag GJ.

J Cancer Res Clin Oncol. 2017 Jun;143(6):961-970. doi: 10.1007/s00432-017-2365-y. Epub 2017 Mar 4.

16.

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma.

Gremel G, Djureinovic D, Niinivirta M, Laird A, Ljungqvist O, Johannesson H, Bergman J, Edqvist PH, Navani S, Khan N, Patil T, Sivertsson Å, Uhlén M, Harrison DJ, Ullenhag GJ, Stewart GD, Pontén F.

BMC Cancer. 2017 Jan 4;17(1):9. doi: 10.1186/s12885-016-3030-6.

17.

Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

Jedlinski A, Garvin S, Johansson AC, Edqvist PH, Ponten F, Roberg K.

J Oral Pathol Med. 2017 Oct;46(9):717-724. doi: 10.1111/jop.12545. Epub 2017 Jan 28.

PMID:
28036101
18.

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.

van Kempen LC, Redpath M, Elchebly M, Klein KO, Papadakis AI, Wilmott JS, Scolyer RA, Edqvist PH, Pontén F, Schadendorf D, van Rijk AF, Michiels S, Dumay A, Helbling-Leclerc A, Dessen P, Wouters J, Stass M, Greenwood CM, Ghanem GE, van den Oord J, Feunteun J, Spatz A.

Sci Transl Med. 2016 Dec 14;8(369):369ra177.

PMID:
27974665
19.

Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data.

Zetterling M, Roodakker KR, Berntsson SG, Edqvist PH, Latini F, Landtblom AM, Pontén F, Alafuzoff I, Larsson EM, Smits A.

J Neurosurg. 2016 Nov;125(5):1155-1166. Epub 2016 Feb 26.

PMID:
26918468
20.

A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression.

Eriksson O, Asplund A, Hegde G, Edqvist PH, Navani S, Pontén F, Siegbahn A.

Thromb Haemost. 2016 Nov 30;116(6):1050-1059. Epub 2016 Sep 22.

PMID:
27656710
21.

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

Roodakker KR, Elsir T, Edqvist PD, Hägerstrand D, Carlson J, Lysiak M, Henriksson R, Pontén F, Rosell J, Söderkvist P, Stupp R, Tchougounova E, Nistér M, Malmström A, Smits A.

Oncotarget. 2016 Nov 8;7(45):72431-72442. doi: 10.18632/oncotarget.11957.

22.

Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.

Kundu S, Xiong A, Spyrou A, Wicher G, Marinescu VD, Edqvist PD, Zhang L, Essand M, Dimberg A, Smits A, Ilan N, Vlodavsky I, Li JP, Forsberg-Nilsson K.

Mol Cancer Res. 2016 Dec;14(12):1243-1253. Epub 2016 Aug 26. Erratum in: Mol Cancer Res. 2018 Apr;16(4):740-741.

23.

Horizontal Cells, the Odd Ones Out in the Retina, Give Insights into Development and Disease.

Boije H, Shirazi Fard S, Edqvist PH, Hallböök F.

Front Neuroanat. 2016 Jul 19;10:77. doi: 10.3389/fnana.2016.00077. eCollection 2016. Review.

24.

Expression of possible targets for new proteasome inhibitors in diffuse large B-cell lymphoma.

Delforoush M, Berglund M, Edqvist PH, Sundström C, Gullbo J, Enblad G.

Eur J Haematol. 2017 Jan;98(1):52-56. doi: 10.1111/ejh.12784. Epub 2016 Jul 12.

PMID:
27301795
25.

SATB2 is expressed in Merkel cell carcinoma.

Fukuhara M, Agnarsdóttir M, Edqvist PH, Coter A, Ponten F.

Arch Dermatol Res. 2016 Aug;308(6):449-54. doi: 10.1007/s00403-016-1655-6. Epub 2016 Jun 4.

PMID:
27262585
26.

Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.

Landegren N, Sharon D, Freyhult E, Hallgren Å, Eriksson D, Edqvist PH, Bensing S, Wahlberg J, Nelson LM, Gustafsson J, Husebye ES, Anderson MS, Snyder M, Kämpe O.

Sci Rep. 2016 Feb 1;6:20104. doi: 10.1038/srep20104.

27.

Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma.

Edqvist PH, Huvila J, Forsström B, Talve L, Carpén O, Salvesen HB, Krakstad C, Grénman S, Johannesson H, Ljungqvist O, Uhlén M, Pontén F, Auranen A.

Gynecol Oncol. 2015 Jun;137(3):529-37. doi: 10.1016/j.ygyno.2015.03.055. Epub 2015 Apr 7.

PMID:
25858696
28.

Proteomics. Tissue-based map of the human proteome.

Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson Å, Kampf C, Sjöstedt E, Asplund A, Olsson I, Edlund K, Lundberg E, Navani S, Szigyarto CA, Odeberg J, Djureinovic D, Takanen JO, Hober S, Alm T, Edqvist PH, Berling H, Tegel H, Mulder J, Rockberg J, Nilsson P, Schwenk JM, Hamsten M, von Feilitzen K, Forsberg M, Persson L, Johansson F, Zwahlen M, von Heijne G, Nielsen J, Pontén F.

Science. 2015 Jan 23;347(6220):1260419. doi: 10.1126/science.1260419.

29.

Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling.

Edqvist PH, Fagerberg L, Hallström BM, Danielsson A, Edlund K, Uhlén M, Pontén F.

J Histochem Cytochem. 2015 Feb;63(2):129-41. doi: 10.1369/0022155414562646. Epub 2014 Nov 19.

30.

FGF2 as a potential prognostic biomarker for proneural glioma patients.

Sooman L, Freyhult E, Jaiswal A, Navani S, Edqvist PH, Pontén F, Tchougounova E, Smits A, Elsir T, Gullbo J, Lennartsson J, Bergqvist M, Ekman S.

Acta Oncol. 2015 Mar;54(3):385-94. doi: 10.3109/0284186X.2014.951492. Epub 2014 Sep 29.

PMID:
25263081
31.

PTPN6 expression is epigenetically regulated and influences survival and response to chemotherapy in high-grade gliomas.

Sooman L, Ekman S, Tsakonas G, Jaiswal A, Navani S, Edqvist PH, Pontén F, Bergström S, Johansson M, Wu X, Blomquist E, Bergqvist M, Gullbo J, Lennartsson J.

Tumour Biol. 2014 May;35(5):4479-88. doi: 10.1007/s13277-013-1590-5. Epub 2014 Feb 9.

PMID:
24510345
32.

Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.

Popova SN, Bergqvist M, Dimberg A, Edqvist PH, Ekman S, Hesselager G, Ponten F, Smits A, Sooman L, Alafuzoff I.

Histopathology. 2014 Feb;64(3):365-79. doi: 10.1111/his.12252. Epub 2013 Nov 5.

33.

A systematic analysis of commonly used antibodies in cancer diagnostics.

Gremel G, Bergman J, Djureinovic D, Edqvist PH, Maindad V, Bharambe BM, Khan WA, Navani S, Elebro J, Jirström K, Hellberg D, Uhlén M, Micke P, Pontén F.

Histopathology. 2014 Jan;64(2):293-305. doi: 10.1111/his.12255. Epub 2013 Nov 5.

PMID:
24330150
34.

Detection of the human endogenous retrovirus ERV3-encoded Env-protein in human tissues using antibody-based proteomics.

Fei C, Atterby C, Edqvist PH, Pontén F, Zhang WW, Larsson E, Ryan FP.

J R Soc Med. 2014 Jan;107(1):22-9. doi: 10.1177/0141076813509981. Epub 2013 Nov 21.

35.

Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner.

Põlajeva J, Bergström T, Edqvist PH, Lundequist A, Sjösten A, Nilsson G, Smits A, Bergqvist M, Pontén F, Westermark B, Pejler G, Forsberg Nilsson K, Tchougounova E.

Mol Oncol. 2014 Feb;8(1):50-8. doi: 10.1016/j.molonc.2013.09.002. Epub 2013 Sep 18.

36.

A study of embryonic stem cell-related proteins in human astrocytomas: identification of Nanog as a predictor of survival.

Elsir T, Edqvist PH, Carlson J, Ribom D, Bergqvist M, Ekman S, Popova SN, Alafuzoff I, Ponten F, Nistér M, Smits A.

Int J Cancer. 2014 Mar 1;134(5):1123-31. doi: 10.1002/ijc.28441. Epub 2013 Sep 16.

37.

Vandetanib combined with a p38 MAPK inhibitor synergistically reduces glioblastoma cell survival.

Sooman L, Lennartsson J, Gullbo J, Bergqvist M, Tsakonas G, Johansson F, Edqvist PH, Pontén F, Jaiswal A, Navani S, Alafuzoff I, Popova S, Blomquist E, Ekman S.

Med Oncol. 2013;30(3):638. doi: 10.1007/s12032-013-0638-0. Epub 2013 Jun 20.

PMID:
23783486
38.

Progesterone receptor negativity is an independent risk factor for relapse in patients with early stage endometrioid endometrial adenocarcinoma.

Huvila J, Talve L, Carpén O, Edqvist PH, Pontén F, Grénman S, Auranen A.

Gynecol Oncol. 2013 Sep;130(3):463-9. doi: 10.1016/j.ygyno.2013.06.015. Epub 2013 Jun 15.

PMID:
23777659
39.

A texture based pattern recognition approach to distinguish melanoma from non-melanoma cells in histopathological tissue microarray sections.

Rexhepaj E, Agnarsdóttir M, Bergman J, Edqvist PH, Bergqvist M, Uhlén M, Gallagher WM, Lundberg E, Ponten F.

PLoS One. 2013 May 17;8(5):e62070. doi: 10.1371/journal.pone.0062070. Print 2013.

40.

Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP).

Fagerberg L, Oksvold P, Skogs M, Algenäs C, Lundberg E, Pontén F, Sivertsson A, Odeberg J, Klevebring D, Kampf C, Asplund A, Sjöstedt E, Al-Khalili Szigyarto C, Edqvist PH, Olsson I, Rydberg U, Hudson P, Ottosson Takanen J, Berling H, Björling L, Tegel H, Rockberg J, Nilsson P, Navani S, Jirström K, Mulder J, Schwenk JM, Zwahlen M, Hober S, Forsberg M, von Feilitzen K, Uhlén M.

J Proteome Res. 2013 Jun 7;12(6):2439-48. doi: 10.1021/pr300924j. Epub 2012 Dec 31.

PMID:
23276153
41.

STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer.

Peña C, Céspedes MV, Lindh MB, Kiflemariam S, Mezheyeuski A, Edqvist PH, Hägglöf C, Birgisson H, Bojmar L, Jirström K, Sandström P, Olsson E, Veerla S, Gallardo A, Sjöblom T, Chang AC, Reddel RR, Mangues R, Augsten M, Ostman A.

Cancer Res. 2013 Feb 15;73(4):1287-97. doi: 10.1158/0008-5472.CAN-12-1875. Epub 2012 Dec 14.

42.

Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.

Edqvist PH, Niklasson M, Vidal-Sanz M, Hallböök F, Forsberg-Nilsson K.

PLoS One. 2012;7(8):e42488. doi: 10.1371/journal.pone.0042488. Epub 2012 Aug 3.

43.

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.

Dieterich LC, Mellberg S, Langenkamp E, Zhang L, Zieba A, Salomäki H, Teichert M, Huang H, Edqvist PH, Kraus T, Augustin HG, Olofsson T, Larsson E, Söderberg O, Molema G, Pontén F, Georgii-Hemming P, Alafuzoff I, Dimberg A.

J Pathol. 2012 Nov;228(3):378-90. doi: 10.1002/path.4072. Epub 2012 Aug 31.

PMID:
22786655
44.

Antibodies for profiling the human proteome-The Human Protein Atlas as a resource for cancer research.

Asplund A, Edqvist PH, Schwenk JM, Pontén F.

Proteomics. 2012 Jul;12(13):2067-77. doi: 10.1002/pmic.201100504.

PMID:
22623277
45.

GABA-A channel subunit expression in human glioma correlates with tumor histology and clinical outcome.

Smits A, Jin Z, Elsir T, Pedder H, Nistér M, Alafuzoff I, Dimberg A, Edqvist PH, Pontén F, Aronica E, Birnir B.

PLoS One. 2012;7(5):e37041. doi: 10.1371/journal.pone.0037041. Epub 2012 May 17.

46.

The Human Protein Atlas as a proteomic resource for biomarker discovery.

Pontén F, Schwenk JM, Asplund A, Edqvist PH.

J Intern Med. 2011 Nov;270(5):428-46. doi: 10.1111/j.1365-2796.2011.02427.x. Epub 2011 Aug 3. Review.

47.

Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells.

Niklasson M, Bergström T, Zhang XQ, Gustafsdottir SM, Sjögren M, Edqvist PH, Vennström B, Forsberg M, Forsberg-Nilsson K.

Exp Cell Res. 2010 Oct 15;316(17):2779-89. doi: 10.1016/j.yexcr.2010.07.009. Epub 2010 Jul 17.

PMID:
20643125
48.

YopD self-assembly and binding to LcrV facilitate type III secretion activity by Yersinia pseudotuberculosis.

Costa TR, Edqvist PJ, Bröms JE, Ahlund MK, Forsberg A, Francis MS.

J Biol Chem. 2010 Aug 13;285(33):25269-84. doi: 10.1074/jbc.M110.144311. Epub 2010 Jun 4.

49.

Horizontal cell progenitors arrest in G2-phase and undergo terminal mitosis on the vitreal side of the chick retina.

Boije H, Edqvist PH, Hallböök F.

Dev Biol. 2009 Jun 1;330(1):105-13. doi: 10.1016/j.ydbio.2009.03.013. Epub 2009 Mar 24.

50.

Axon-bearing and axon-less horizontal cell subtypes are generated consecutively during chick retinal development from progenitors that are sensitive to follistatin.

Edqvist PH, Lek M, Boije H, Lindbäck SM, Hallböök F.

BMC Dev Biol. 2008 Apr 25;8:46. doi: 10.1186/1471-213X-8-46.

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