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Items: 7


PSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in mice.

Langut Y, Talhami A, Mamidi S, Shir A, Zigler M, Joubran S, Sagalov A, Flashner-Abramson E, Edinger N, Klein S, Levitzki A.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13655-13660. doi: 10.1073/pnas.1714587115. Epub 2017 Dec 11.


S101, an Inhibitor of Proliferating T Cells, Rescues Mice From Superantigen-Induced Shock.

Shir A, Klein S, Sagiv-Barfi I, Geiger T, Zigler M, Langut Y, Edinger N, Levitzki A.

J Infect Dis. 2018 Jan 4;217(2):288-297. doi: 10.1093/infdis/jix576.


PSMA-homing dsRNA chimeric protein vector kills prostate cancer cells and activates anti-tumor bystander responses.

Langut Y, Edinger N, Flashner-Abramson E, Melamed-Book N, Lebendiker M, Levi-Kalisman Y, Klein S, Levitzki A.

Oncotarget. 2017 Apr 11;8(15):24046-24062. doi: 10.18632/oncotarget.15733.


Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF.

Edinger N, Lebendiker M, Klein S, Zigler M, Langut Y, Levitzki A.

PLoS One. 2016 Sep 6;11(9):e0162321. doi: 10.1371/journal.pone.0162321. eCollection 2016.


HER2-Targeted Polyinosine/Polycytosine Therapy Inhibits Tumor Growth and Modulates the Tumor Immune Microenvironment.

Zigler M, Shir A, Joubran S, Sagalov A, Klein S, Edinger N, Lau J, Yu SF, Mizraji G, Globerson Levin A, Sliwkowski MX, Levitzki A.

Cancer Immunol Res. 2016 Aug;4(8):688-97. doi: 10.1158/2326-6066.CIR-15-0203. Epub 2016 May 30.


Optimization of liganded polyethylenimine polyethylene glycol vector for nucleic acid delivery.

Joubran S, Zigler M, Pessah N, Klein S, Shir A, Edinger N, Sagalov A, Razvag Y, Reches M, Levitzki A.

Bioconjug Chem. 2014 Sep 17;25(9):1644-54. doi: 10.1021/bc500252a. Epub 2014 Aug 14.


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