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Items: 1 to 50 of 266

1.

Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis.

Lin Y, Qiu Y, Xu C, Liu Q, Peng B, Kaufmann GF, Chen X, Lan B, Wei C, Lu D, Zhang Y, Guo Y, Lu Z, Jiang B, Edgington TS, Guo F.

J Natl Cancer Inst. 2014 Apr;106(4):dju012. doi: 10.1093/jnci/dju012. Epub 2014 Mar 7.

PMID:
24610907
2.

The extrinsic coagulation cascade and tissue factor pathway inhibitor in macrophages: a potential therapeutic opportunity for atherosclerotic thrombosis.

Jiang P, Xue D, Zhang Y, Ye L, Liu Y, Makale M, Kesari S, Edgington TS, Liu C.

Thromb Res. 2014 Apr;133(4):657-66. doi: 10.1016/j.thromres.2014.01.012. Epub 2014 Jan 15.

PMID:
24485401
3.

Dose-dependent modulation of tissue factor protein and procoagulant activity in human monocyte-derived macrophages by oxidized low density lipoprotein.

Meisel SR, Xu XP, Edgington TS, Cercek B, Ong J, Kaul S, Shah PK.

J Atheroscler Thromb. 2011;18(7):596-603. Epub 2011 Apr 4.

4.

Control of RNA processing by a large non-coding RNA over-expressed in carcinomas.

Lin R, Roychowdhury-Saha M, Black C, Watt AT, Marcusson EG, Freier SM, Edgington TS.

FEBS Lett. 2011 Feb 18;585(4):671-6. doi: 10.1016/j.febslet.2011.01.030. Epub 2011 Jan 23.

5.

Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].

Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, Kaushal S, Bristow JM, Edgington TS, Hoffman RM, Bouvet M, Yates JR 3rd, Klemke RL.

Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10920-5. doi: 10.1073/pnas.0914776107. Epub 2010 Jun 1. Erratum in: Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13556.

6.

Prolonged hypercholesterolemia-induced tissue factor expression in rabbit vein grafts: a potential mechanism for graft failure.

Meisel SR, Ouyang Y, Fishbein MC, Edgington TS, Ruan XM, Cercek B, Shah PK, Chaux A.

Coron Artery Dis. 2010 Mar;21(2):97-103. doi: 10.1097/MCA.0b013e328336e9f3.

PMID:
20087175
7.

Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1.

Bhattacharjee G, Ahamed J, Pawlinski R, Liu C, Mackman N, Ruf W, Edgington TS.

Circ Res. 2008 Feb 29;102(4):457-64. doi: 10.1161/CIRCRESAHA.107.167759. Epub 2008 Jan 3.

8.
9.

A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas.

Lin R, Maeda S, Liu C, Karin M, Edgington TS.

Oncogene. 2007 Feb 8;26(6):851-8. Epub 2006 Jul 31.

PMID:
16878148
10.

A recombinant human enzyme for enhanced interstitial transport of therapeutics.

Bookbinder LH, Hofer A, Haller MF, Zepeda ML, Keller GA, Lim JE, Edgington TS, Shepard HM, Patton JS, Frost GI.

J Control Release. 2006 Aug 28;114(2):230-41. Epub 2006 Jun 7.

PMID:
16876899
11.

Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms.

Wu W, Luo Y, Sun C, Liu Y, Kuo P, Varga J, Xiang R, Reisfeld R, Janda KD, Edgington TS, Liu C.

Cancer Res. 2006 Jan 15;66(2):970-80.

12.

A selective tumor microvasculature thrombogen that targets a novel receptor complex in the tumor angiogenic microenvironment.

El-Sheikh A, Borgstrom P, Bhattacharjee G, Belting M, Edgington TS.

Cancer Res. 2005 Dec 1;65(23):11109-17.

13.

Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78.

Bhattacharjee G, Ahamed J, Pedersen B, El-Sheikh A, Mackman N, Ruf W, Liu C, Edgington TS.

Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1737-43. Epub 2005 Jun 9.

PMID:
15947236
14.

Platelet-induced expression of tissue factor procoagulant activity in freshly isolated human mononuclear cells: implications for experimental use.

Meisel SR, Shechter M, Xu XP, Edgington TS, Cercek B, Shah PK.

Clin Lab Haematol. 2003 Oct;25(5):321-5.

PMID:
12974724
15.
17.

Prostate-specific membrane antigen directed selective thrombotic infarction of tumors.

Liu C, Huang H, Doñate F, Dickinson C, Santucci R, El-Sheikh A, Vessella R, Edgington TS.

Cancer Res. 2002 Oct 1;62(19):5470-5.

18.

Differentiation of adherent human monocytes into macrophages markedly enhances tissue factor protein expression and procoagulant activity.

Meisel SR, Xu XP, Edgington TS, Dimayuga P, Kaul S, Lee S, Fishbein MC, Cercek B, Shah PK.

Atherosclerosis. 2002 Mar;161(1):35-43.

PMID:
11882315
19.
20.
21.

Association between the molecular pathobiology of essential hypertension and thrombotic diseases.

Edgington TS.

Am J Pathol. 2000 Jul;157(1):5-6. No abstract available.

22.

Leukaemia inhibitory factor enhances tissue factor expression in human monocyte-derived macrophages: a gp130-mediated mechanism.

Meisel SR, Shimon I, Edgington TS, Melmed S, Cercek B, Shah PK.

Br J Haematol. 1999 Dec;107(4):747-55.

PMID:
10606879
23.

Macromolecular substrate affinity for the tissue factor-factor VIIa complex is independent of scissile bond docking.

Shobe J, Dickinson CD, Edgington TS, Ruf W.

J Biol Chem. 1999 Aug 20;274(34):24171-5.

24.

Importance of factor VIIa Gla-domain residue Arg-36 for recognition of the macromolecular substrate factor X Gla-domain.

Ruf W, Shobe J, Rao SM, Dickinson CD, Olson A, Edgington TS.

Biochemistry. 1999 Feb 16;38(7):1957-66.

PMID:
10026279
25.

The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex.

Huang M, Syed R, Stura EA, Stone MJ, Stefanko RS, Ruf W, Edgington TS, Wilson IA.

J Mol Biol. 1998 Feb 6;275(5):873-94.

PMID:
9480775
26.

Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer.

Shoji M, Hancock WW, Abe K, Micko C, Casper KA, Baine RM, Wilcox JN, Danave I, Dillehay DL, Matthews E, Contrino J, Morrissey JH, Gordon S, Edgington TS, Kudryk B, Kreutzer DL, Rickles FR.

Am J Pathol. 1998 Feb;152(2):399-411. Review.

28.

The structural basis of function of the TF. VIIa complex in the cellular initiation of coagulation.

Edgington TS, Dickinson CD, Ruf W.

Thromb Haemost. 1997 Jul;78(1):401-5. Review.

PMID:
9198187
29.

Angiostatic therapy gets moving.

Huang X, Molema C, King S, Watkins L, Edgington TS, Thorpe PE.

Trends Cell Biol. 1997 May;7(5):180. No abstract available.

PMID:
17708939
30.
31.

Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature.

Huang X, Molema G, King S, Watkins L, Edgington TS, Thorpe PE.

Science. 1997 Jan 24;275(5299):547-50.

32.

Effector cell protease receptor-1 is a vascular receptor for coagulation factor Xa.

Nicholson AC, Nachman RL, Altieri DC, Summers BD, Ruf W, Edgington TS, Hajjar DP.

J Biol Chem. 1996 Nov 8;271(45):28407-13.

33.

Tissue Factor residue Asp44 regulates catalytic function of the bound proteinase Factor VIIa.

Kelly CR, Schullek JR, Ruf W, Edgington TS.

Biochem J. 1996 Apr 1;315 ( Pt 1):145-51.

34.

Procoagulant activity on injured arteries and associated thrombi is mediated primarily by the complex of tissue factor and factor VIIa.

Speidel CM, Thornton JD, Meng YY, Eisenberg PR, Edgington TS, Abendschein DR.

Coron Artery Dis. 1996 Jan;7(1):57-62.

PMID:
8773434
35.

Tissue factor mediates prolonged procoagulant activity on the luminal surface of balloon-injured aortas in rabbits.

Speidel CM, Eisenberg PR, Ruf W, Edgington TS, Abendschein DR.

Circulation. 1995 Dec 1;92(11):3323-30.

PMID:
7586321
37.

Vascular biology: integrative molecular cell biology.

Edgington TS.

FASEB J. 1995 Jul;9(10):841-2. No abstract available.

PMID:
7615153
38.

Energetic contributions and topographical organization of ligand binding residues of tissue factor.

Ruf W, Kelly CR, Schullek JR, Martin DM, Polikarpov I, Boys CW, Tuddenham EG, Edgington TS.

Biochemistry. 1995 May 16;34(19):6310-5.

PMID:
7756258
39.

The other AIDS crisis.

Edgington TS.

FASEB J. 1995 Apr;9(7):467. No abstract available.

PMID:
7737452
40.
41.

Looking to the future of the life sciences.

Edgington TS.

FASEB J. 1994 Dec;8(15):1213. No abstract available.

PMID:
8001730
42.

NIH funding policy.

Edgington TS.

FASEB J. 1994 Nov;8(14):1203; author reply 1203-4. No abstract available.

PMID:
7958629
43.

Defense.

Edgington TS.

FASEB J. 1994 Nov;8(14):1101. No abstract available.

PMID:
7958612
44.

Intellectual property rights.

Edgington TS.

FASEB J. 1994 Sep;8(12):901. No abstract available.

PMID:
8088455
46.

Key ligand interface residues in tissue factor contribute independently to factor VIIa binding.

Schullek JR, Ruf W, Edgington TS.

J Biol Chem. 1994 Jul 29;269(30):19399-403.

47.

High molecular weight kininogen binds to Mac-1 on neutrophils by its heavy chain (domain 3) and its light chain (domain 5).

Wachtfogel YT, DeLa Cadena RA, Kunapuli SP, Rick L, Miller M, Schultze RL, Altieri DC, Edgington TS, Colman RW.

J Biol Chem. 1994 Jul 29;269(30):19307-12.

49.
50.

The train has left the station.

Edgington TS.

FASEB J. 1994 May;8(8):469. No abstract available.

PMID:
8181663

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