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Items: 1 to 50 of 65

1.

The United Kingdom Primary Immune Deficiency (UKPID) registry 2012 to 2017.

Shillitoe B, Bangs C, Guzman D, Gennery AR, Longhurst HJ, Slatter M, Edgar DM, Thomas M, Worth A, Huissoon A, Arkwright PD, Jolles S, Bourne H, Alachkar H, Savic S, Kumararatne DS, Patel S, Baxendale H, Noorani S, Yong PFK, Waruiru C, Pavaladurai V, Kelleher P, Herriot R, Bernatonienne J, Bhole M, Steele C, Hayman G, Richter A, Gompels M, Chopra C, Garcez T, Buckland M.

Clin Exp Immunol. 2018 Jun;192(3):284-291. doi: 10.1111/cei.13125.

2.

X-linked Inhibitor of Apoptosis Complicated by Granulomatous Lymphocytic Interstitial Lung Disease (GLILD) and Granulomatous Hepatitis.

Steele CL, Doré M, Ammann S, Loughrey M, Montero A, Burns SO, Morris EC, Gaspar B, Gilmour K, Bibi S, Shendi H, Devlin L, Speckmann C, Edgar DM.

J Clin Immunol. 2016 Oct;36(7):733-8. doi: 10.1007/s10875-016-0320-3. Epub 2016 Aug 5.

PMID:
27492372
3.

REM sleep homeostasis in the absence of REM sleep: Effects of antidepressants.

McCarthy A, Wafford K, Shanks E, Ligocki M, Edgar DM, Dijk DJ.

Neuropharmacology. 2016 Sep;108:415-25. doi: 10.1016/j.neuropharm.2016.04.047. Epub 2016 May 2.

4.

Distinct pro-vigilant profile induced in rats by the mGluR5 potentiator LSN2814617.

Loomis S, McCarthy A, Baxter C, Kellett DO, Edgar DM, Tricklebank M, Gilmour G.

Psychopharmacology (Berl). 2015 Nov;232(21-22):3977-89. doi: 10.1007/s00213-015-3936-8. Epub 2015 Apr 24.

5.

Decoupling of sleep-dependent cortical and hippocampal interactions in a neurodevelopmental model of schizophrenia.

Phillips KG, Bartsch U, McCarthy AP, Edgar DM, Tricklebank MD, Wafford KA, Jones MW.

Neuron. 2012 Nov 8;76(3):526-33. doi: 10.1016/j.neuron.2012.09.016.

6.

In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat.

Gilmour G, Broad LM, Wafford KA, Britton T, Colvin EM, Fivush A, Gastambide F, Getman B, Heinz BA, McCarthy AP, Prieto L, Shanks E, Smith JW, Taboada L, Edgar DM, Tricklebank MD.

Neuropharmacology. 2013 Jan;64:224-39. doi: 10.1016/j.neuropharm.2012.07.030. Epub 2012 Aug 1.

PMID:
22884720
7.

Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia.

Phillips KG, Cotel MC, McCarthy AP, Edgar DM, Tricklebank M, O'Neill MJ, Jones MW, Wafford KA.

Neuropharmacology. 2012 Mar;62(3):1359-70. doi: 10.1016/j.neuropharm.2011.04.006. Epub 2011 Apr 19.

PMID:
21521646
8.

Hibernation in black bears: independence of metabolic suppression from body temperature.

Tøien Ø, Blake J, Edgar DM, Grahn DA, Heller HC, Barnes BM.

Science. 2011 Feb 18;331(6019):906-9. doi: 10.1126/science.1199435.

9.

N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes.

Fell MJ, Witkin JM, Falcone JF, Katner JS, Perry KW, Hart J, Rorick-Kehn L, Overshiner CD, Rasmussen K, Chaney SF, Benvenga MJ, Li X, Marlow DL, Thompson LK, Luecke SK, Wafford KA, Seidel WF, Edgar DM, Quets AT, Felder CC, Wang X, Heinz BA, Nikolayev A, Kuo MS, Mayhugh D, Khilevich A, Zhang D, Ebert PJ, Eckstein JA, Ackermann BL, Swanson SP, Catlow JT, Dean RA, Jackson K, Tauscher-Wisniewski S, Marek GJ, Schkeryantz JM, Svensson KA.

J Pharmacol Exp Ther. 2011 Jan;336(1):165-77. doi: 10.1124/jpet.110.172957. Epub 2010 Oct 14.

PMID:
20947638
10.

Suspected anaphylactic reactions associated with anaesthesia.

Harper NJ, Dixon T, Dugué P, Edgar DM, Fay A, Gooi HC, Herriot R, Hopkins P, Hunter JM, Mirakian R, Pumphrey RS, Seneviratne SL, Walls AF, Williams P, Wildsmith JA, Wood P, Nasser AS, Powell RK, Mirakhur R, Soar J; Working Party of the Association of Anaesthetists of Great Britain and Ireland.

Anaesthesia. 2009 Feb;64(2):199-211. doi: 10.1111/j.1365-2044.2008.05733.x. No abstract available.

11.

A novel quantitative trait locus on mouse chromosome 18, "era1," modifies the entrainment of circadian rhythms.

Wisor JP, Striz M, DeVoss J, Murphy GM Jr, Edgar DM, O'Hara BF.

Sleep. 2007 Oct;30(10):1255-63.

12.

Gene expression in the rat brain during sleep deprivation and recovery sleep: an Affymetrix GeneChip study.

Terao A, Wisor JP, Peyron C, Apte-Deshpande A, Wurts SW, Edgar DM, Kilduff TS.

Neuroscience. 2006;137(2):593-605. Epub 2005 Oct 28.

13.

Sleep and circadian abnormalities in a transgenic mouse model of Alzheimer's disease: a role for cholinergic transmission.

Wisor JP, Edgar DM, Yesavage J, Ryan HS, McCormick CM, Lapustea N, Murphy GM Jr.

Neuroscience. 2005;131(2):375-85.

PMID:
15708480
14.

Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release.

Zhang S, Zeitzer JM, Yoshida Y, Wisor JP, Nishino S, Edgar DM, Mignot E.

Sleep. 2004 Jun 15;27(4):619-27.

PMID:
15282996
15.

Altered rapid eye movement sleep timing in serotonin transporter knockout mice.

Wisor JP, Wurts SW, Hall FS, Lesch KP, Murphy DL, Uhl GR, Edgar DM.

Neuroreport. 2003 Feb 10;14(2):233-8.

PMID:
12598736
16.

Signature profiles in sleep-wake drug discovery.

Edgar DM.

Methods Find Exp Clin Pharmacol. 2002;24 Suppl D:71-2. No abstract available.

PMID:
12575472
17.

A role for cryptochromes in sleep regulation.

Wisor JP, O'Hara BF, Terao A, Selby CP, Kilduff TS, Sancar A, Edgar DM, Franken P.

BMC Neurosci. 2002 Dec 20;3:20. Epub 2002 Dec 20.

18.

Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptor.

Wisor JP, DeLorey TM, Homanics GE, Edgar DM.

Brain Res. 2002 Nov 15;955(1-2):221-8.

PMID:
12419540
19.

EEG delta activity during undisturbed sleep in the squirrel monkey.

Klerman EB, Boulos Z, Edgar DM, Mistlberger RE, Moore-Ede MC.

Sleep Res Online. 2000;3(3):113-9.

PMID:
11382909
20.
21.

Dopaminergic role in stimulant-induced wakefulness.

Wisor JP, Nishino S, Sora I, Uhl GH, Mignot E, Edgar DM.

J Neurosci. 2001 Mar 1;21(5):1787-94.

22.

Prepro-hypocretin (prepro-orexin) expression is unaffected by short-term sleep deprivation in rats and mice.

Terao A, Peyron C, Ding J, Wurts SW, Edgar DM, Heller HC, Kilduff TS.

Sleep. 2000 Nov 1;23(7):867-74.

PMID:
11083595
24.

Photic phase response curve in Octodon degus: assessment as a function of activity phase preference.

Kas MJ, Edgar DM.

Am J Physiol Regul Integr Comp Physiol. 2000 May;278(5):R1385-9.

25.

Caffeine during sleep deprivation: sleep tendency and dynamics of recovery sleep in rats.

Wurts SW, Edgar DM.

Pharmacol Biochem Behav. 2000 Jan 1;65(1):155-62.

PMID:
10638649
26.
27.

Response-rate suppression in operant paradigm as predictor of soporific potency in rats and identification of three novel sedative-hypnotic neuroactive steroids.

Vanover KE, Edgar DM, Seidel WF, Hogenkamp DJ, Fick DB, Lan NC, Gee KW, Carter RB.

J Pharmacol Exp Ther. 1999 Dec;291(3):1317-23.

PMID:
10565857
28.

Circadian and homeostatic influences on sleep in the squirrel monkey: sleep after sleep deprivation.

Klerman EB, Boulos Z, Edgar DM, Mistlberger RE, Moore-Ede MC.

Sleep. 1999 Feb 1;22(1):45-59.

PMID:
9989365
29.
30.

Effects of adrenalectomy and subsequent corticosterone replacement on rat sleep state and EEG power spectra.

Bradbury MJ, Dement WC, Edgar DM.

Am J Physiol. 1998 Aug;275(2):R555-65. doi: 10.1152/ajpregu.1998.275.2.R555.

PMID:
9688693
31.

Compensatory sleep responses to wakefulness induced by the dopamine autoreceptor antagonist (-)DS121.

Olive MF, Seidel WF, Edgar DM.

J Pharmacol Exp Ther. 1998 Jun;285(3):1073-83.

PMID:
9618410
32.

Nicotine and nicotinic receptors in the circadian system.

O'Hara BF, Edgar DM, Cao VH, Wiler SW, Heller HC, Kilduff TS, Miller JD.

Psychoneuroendocrinology. 1998 Feb;23(2):161-73. Review.

PMID:
9621396
33.

Crepuscular rhythms of EEG sleep-wake in a hystricomorph rodent, Octodon degus.

Kas MJ, Edgar DM.

J Biol Rhythms. 1998 Feb;13(1):9-17.

PMID:
9486839
34.

The aged suprachiasmatic nucleus is phase-shifted by cAMP in vitro.

Ruby NF, Edgar DM, Heller HC, Miller JD.

Brain Res. 1998 Jan 1;779(1-2):338-41.

PMID:
9473717
35.

Sleep-promoting effects of melatonin: at what dose, in whom, under what conditions, and by what mechanisms?

Sack RL, Hughes RJ, Edgar DM, Lewy AJ.

Sleep. 1997 Oct;20(10):908-15. Review.

PMID:
9415954
36.

Serotonin-containing fibers in the suprachiasmatic hypothalamus attenuate light-induced phase delays in mice.

Bradbury MJ, Dement WC, Edgar DM.

Brain Res. 1997 Sep 12;768(1-2):125-34.

PMID:
9369309
37.
38.

Serotonergic afferents mediate activity-dependent entrainment of the mouse circadian clock.

Edgar DM, Reid MS, Dement WC.

Am J Physiol. 1997 Jul;273(1 Pt 2):R265-9.

PMID:
9249559
39.

CCD-3693: an orally bioavailable analog of the endogenous neuroactive steroid, pregnanolone, demonstrates potent sedative hypnotic actions in the rat.

Edgar DM, Seidel WF, Gee KW, Lan NC, Field G, Xia H, Hawkinson JE, Wieland S, Carter RB, Wood PL.

J Pharmacol Exp Ther. 1997 Jul;282(1):420-9.

PMID:
9223583
40.

Alpha-2 adrenergic modulation of sleep: time-of-day-dependent pharmacodynamic profiles of dexmedetomidine and clonidine in the rat.

Seidel WF, Maze M, Dement WC, Edgar DM.

J Pharmacol Exp Ther. 1995 Oct;275(1):263-73.

PMID:
7562559
41.

Biological rhythmicity in preterm infants prior to discharge from neonatal intensive care.

Glotzbach SF, Edgar DM, Ariagno RL.

Pediatrics. 1995 Feb;95(2):231-7.

PMID:
7838641
42.

Biological rhythmicity in normal infants during the first 3 months of life.

Glotzbach SF, Edgar DM, Boeddiker M, Ariagno RL.

Pediatrics. 1994 Oct;94(4 Pt 1):482-8.

PMID:
7936856
43.

Sleep-wake circadian rhythms and aging: potential etiologies and relevance to age-related changes in integrated physiological systems.

Edgar DM.

Neurobiol Aging. 1994 Jul-Aug;15(4):499-501. Review. No abstract available.

PMID:
7969730
44.
45.

A possible glial role in the mammalian circadian clock.

Prosser RA, Edgar DM, Heller HC, Miller JD.

Brain Res. 1994 Apr 18;643(1-2):296-301.

PMID:
8032923
46.

Pedunculated uterine fibroid simulating an incarcerated inguinal hernia in pregnancy.

Sherer DM, Edgar DM, Pulli GJ, Scibetta JJ.

Am J Obstet Gynecol. 1994 Mar;170(3):724-5.

PMID:
8141189
47.

Circadian rhythms in narcolepsy: studies on a 90 minute day.

Dantz B, Edgar DM, Dement WC.

Electroencephalogr Clin Neurophysiol. 1994 Jan;90(1):24-35.

PMID:
7509271
48.

Light variability in the modern neonatal nursery: chronobiologic issues.

Glotzbach SF, Rowlett EA, Edgar DM, Moffat RJ, Ariagno RL.

Med Hypotheses. 1993 Sep;41(3):217-24.

PMID:
8259078
49.

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