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Items: 1 to 50 of 187

1.

Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut.

Patel PH, Pénalva C, Kardorff M, Roca M, Pavlović B, Thiel A, Teleman AA, Edgar BA.

Nat Commun. 2019 Sep 25;10(1):4365. doi: 10.1038/s41467-019-12336-w.

2.

Tumor suppressive autophagy in intestinal stem cells controls gut homeostasis.

Zhang P, Holowatyj AN, Ulrich CM, Edgar BA.

Autophagy. 2019 Sep;15(9):1668-1670. doi: 10.1080/15548627.2019.1633863. Epub 2019 Jun 20.

PMID:
31213134
3.

An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling.

Zhang P, Holowatyj AN, Roy T, Pronovost SM, Marchetti M, Liu H, Ulrich CM, Edgar BA.

Dev Cell. 2019 May 20;49(4):574-589.e5. doi: 10.1016/j.devcel.2019.03.029. Epub 2019 Apr 18.

PMID:
31006650
4.

Incorporate Indigenous perspectives for impactful research and effective management.

Ban NC, Frid A, Reid M, Edgar B, Shaw D, Siwallace P.

Nat Ecol Evol. 2018 Nov;2(11):1680-1683. doi: 10.1038/s41559-018-0706-0. No abstract available.

PMID:
30349090
5.

Experiences of transmasculine spectrum people who report nonsuicidal self-injury: A qualitative investigation.

Jackman K, Edgar B, Ling A, Honig J, Bockting W.

J Couns Psychol. 2018 Oct;65(5):586-597. doi: 10.1037/cou0000304. Epub 2018 Aug 2.

6.

Polyploidy in tissue homeostasis and regeneration.

Øvrebø JI, Edgar BA.

Development. 2018 Jul 18;145(14). pii: dev156034. doi: 10.1242/dev.156034. Review.

7.

Enhanced expression of thioredoxin-interacting-protein regulates oxidative DNA damage and aging.

Oberacker T, Bajorat J, Ziola S, Schroeder A, Röth D, Kastl L, Edgar BA, Wagner W, Gülow K, Krammer PH.

FEBS Lett. 2018 Jul;592(13):2297-2307. doi: 10.1002/1873-3468.13156. Epub 2018 Jun 27.

8.

In Vivo Analysis of Centromeric Proteins Reveals a Stem Cell-Specific Asymmetry and an Essential Role in Differentiated, Non-proliferating Cells.

García Del Arco A, Edgar BA, Erhardt S.

Cell Rep. 2018 Feb 20;22(8):1982-1993. doi: 10.1016/j.celrep.2018.01.079.

9.

Longer life through an odd Pol enzyme.

Edgar BA, Grewal SS.

Nature. 2017 Dec 14;552(7684):182-183. doi: 10.1038/d41586-017-07435-x. No abstract available.

PMID:
29239369
10.

A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size.

Zhang P, Pei C, Wang X, Xiang J, Sun BF, Cheng Y, Qi X, Marchetti M, Xu JW, Sun YP, Edgar BA, Yuan Z.

Dev Cell. 2017 Dec 4;43(5):603-617.e5. doi: 10.1016/j.devcel.2017.10.033.

11.

Health Literacy and Atrial Fibrillation: Relevance and Future Directions for Patient-centred Care.

Aronis KN, Edgar B, Lin W, Martins MAP, Paasche-Orlow MK, Magnani JW.

Eur Cardiol. 2017 Summer;12(1):52-7. doi: 10.15420/ecr.2017:2:2.

12.

EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration.

Xiang J, Bandura J, Zhang P, Jin Y, Reuter H, Edgar BA.

Nat Commun. 2017 May 9;8:15125. doi: 10.1038/ncomms15125.

13.

Intestinal Stem Cell Pool Regulation in Drosophila.

Jin Y, Patel PH, Kohlmaier A, Pavlovic B, Zhang C, Edgar BA.

Stem Cell Reports. 2017 Jun 6;8(6):1479-1487. doi: 10.1016/j.stemcr.2017.04.002. Epub 2017 May 4.

14.

ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration.

Zhou J, Edgar BA, Boutros M.

Nat Commun. 2017 Mar 8;8:14289. doi: 10.1038/ncomms14289.

15.

Activation of the Tor/Myc signaling axis in intestinal stem and progenitor cells affects longevity, stress resistance and metabolism in drosophila.

Strilbytska OM, Semaniuk UV, Storey KB, Edgar BA, Lushchak OV.

Comp Biochem Physiol B Biochem Mol Biol. 2017 Jan;203:92-99. doi: 10.1016/j.cbpb.2016.09.008. Epub 2016 Sep 29.

PMID:
27693629
16.

EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes.

Jin Y, Ha N, Forés M, Xiang J, Gläßer C, Maldera J, Jiménez G, Edgar BA.

PLoS Genet. 2015 Dec 18;11(12):e1005634. doi: 10.1371/journal.pgen.1005634. eCollection 2015 Dec.

17.

AF-1 a novel regulator of the redox equilibrium during aging.

Bajorat J, Oberacker T, Ziola S, Edgar BA, Gülow K, Krammer PH.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S22-3. doi: 10.1016/j.freeradbiomed.2014.10.737. Epub 2014 Dec 10.

PMID:
26461309
18.

Using the Fly-FUCCI System for the Live Analysis of Cell Cycle Dynamics in Cultured Drosophila Cells.

Zielke N, van Straaten M, Bohlen J, Edgar BA.

Methods Mol Biol. 2016;1342:305-20. doi: 10.1007/978-1-4939-2957-3_19.

PMID:
26254933
19.

Niche appropriation by Drosophila intestinal stem cell tumours.

Patel PH, Dutta D, Edgar BA.

Nat Cell Biol. 2015 Sep;17(9):1182-92. doi: 10.1038/ncb3214. Epub 2015 Aug 3.

20.

Regional Cell Specific RNA Expression Profiling of FACS Isolated Drosophila Intestinal Cell Populations.

Dutta D, Buchon N, Xiang J, Edgar BA.

Curr Protoc Stem Cell Biol. 2015 Aug 3;34:2F.2.1-14. doi: 10.1002/9780470151808.sc02f02s34.

PMID:
26237570
21.

Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress.

Icreverzi A, de la Cruz AF, Walker DW, Edgar BA.

Aging Cell. 2015 Oct;14(5):896-906. doi: 10.1111/acel.12376. Epub 2015 Jul 29.

22.

Indwelling urinary catheter surveillance using a Task-oriented nurse acuity system.

Leis JA, Corpus C, Catt B, Jinnah F, Edgar B, Wong BM, Callery S, Simor AE, Vearncombe M.

Am J Infect Control. 2015 Oct 1;43(10):1112-3. doi: 10.1016/j.ajic.2015.05.046. Epub 2015 Jul 17.

PMID:
26190387
23.

Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut.

Dutta D, Dobson AJ, Houtz PL, Gläßer C, Revah J, Korzelius J, Patel PH, Edgar BA, Buchon N.

Cell Rep. 2015 Jul 14;12(2):346-58. doi: 10.1016/j.celrep.2015.06.009. Epub 2015 Jul 2.

24.

FUCCI sensors: powerful new tools for analysis of cell proliferation.

Zielke N, Edgar BA.

Wiley Interdiscip Rev Dev Biol. 2015 Sep-Oct;4(5):469-87. doi: 10.1002/wdev.189. Epub 2015 Apr 1. Review.

25.

Dpp/Gbb signaling is required for normal intestinal regeneration during infection.

Zhou J, Florescu S, Boettcher AL, Luo L, Dutta D, Kerr G, Cai Y, Edgar BA, Boutros M.

Dev Biol. 2015 Mar 15;399(2):189-203. doi: 10.1016/j.ydbio.2014.12.017. Epub 2014 Dec 29.

26.

Escargot maintains stemness and suppresses differentiation in Drosophila intestinal stem cells.

Korzelius J, Naumann SK, Loza-Coll MA, Chan JS, Dutta D, Oberheim J, Gläßer C, Southall TD, Brand AH, Jones DL, Edgar BA.

EMBO J. 2014 Dec 17;33(24):2967-82. doi: 10.15252/embj.201489072. Epub 2014 Oct 8.

27.

Power of two.

Edgar B.

Sci Am. 2014 Sep;311(3):62-7. No abstract available.

PMID:
25211906
28.

Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine.

Kohlmaier A, Fassnacht C, Jin Y, Reuter H, Begum J, Dutta D, Edgar BA.

Oncogene. 2015 Apr 30;34(18):2371-84. doi: 10.1038/onc.2014.163. Epub 2014 Jun 30.

PMID:
24975577
29.
30.

Fly-FUCCI: A versatile tool for studying cell proliferation in complex tissues.

Zielke N, Korzelius J, van Straaten M, Bender K, Schuhknecht GFP, Dutta D, Xiang J, Edgar BA.

Cell Rep. 2014 Apr 24;7(2):588-598. doi: 10.1016/j.celrep.2014.03.020. Epub 2014 Apr 13.

31.

Tissue design: how Drosophila tumors remodel their neighborhood.

Patel PH, Edgar BA.

Semin Cell Dev Biol. 2014 Apr;28:86-95. doi: 10.1016/j.semcdb.2014.03.012. Epub 2014 Mar 28. Review.

PMID:
24685612
32.

Temporal regulation of Dpp signaling output in the Drosophila wing.

O'Keefe DD, Thomas S, Edgar BA, Buttitta L.

Dev Dyn. 2014 Jun;243(6):818-32. doi: 10.1002/dvdy.24122. Epub 2014 Mar 21.

33.

Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth.

Edgar BA, Zielke N, Gutierrez C.

Nat Rev Mol Cell Biol. 2014 Mar;15(3):197-210. doi: 10.1038/nrm3756. Review. Erratum in: Nat Rev Mol Cell Biol. 2014 Apr;15(4):294.

PMID:
24556841
34.

RNA expression profiling from FACS-isolated cells of the Drosophila intestine.

Dutta D, Xiang J, Edgar BA.

Curr Protoc Stem Cell Biol. 2013 Nov 13;27:Unit 2F.2.. doi: 10.1002/9780470151808.sc02f02s27.

PMID:
24510286
35.

Hunting complex differential gene interaction patterns across molecular contexts.

Song M, Zhang Y, Katzaroff AJ, Edgar BA, Buttitta L.

Nucleic Acids Res. 2014 Apr;42(7):e57. doi: 10.1093/nar/gku086. Epub 2014 Jan 29.

36.

Stimulating cROSstalk between commensal bacteria and intestinal stem cells.

Patel PH, Maldera JA, Edgar BA.

EMBO J. 2013 Nov 27;32(23):3009-10. doi: 10.1038/emboj.2013.244. Epub 2013 Nov 5. No abstract available.

37.

Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110.

Kuo Y, Ren S, Lao U, Edgar BA, Wang T.

Cell Death Dis. 2013 Oct 3;4:e833. doi: 10.1038/cddis.2013.351.

38.

The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster.

Bandura JL, Jiang H, Nickerson DW, Edgar BA.

PLoS Genet. 2013;9(9):e1003835. doi: 10.1371/journal.pgen.1003835. Epub 2013 Sep 26.

39.

Brk regulates wing disc growth in part via repression of Myc expression.

Doumpas N, Ruiz-Romero M, Blanco E, Edgar B, Corominas M, Teleman AA.

EMBO Rep. 2013 Mar 1;14(3):261-8. doi: 10.1038/embor.2013.1. Epub 2013 Jan 22.

40.

Endoreplication.

Zielke N, Edgar BA, DePamphilis ML.

Cold Spring Harb Perspect Biol. 2013 Jan 1;5(1):a012948. doi: 10.1101/cshperspect.a012948. Review.

41.

The small GTPase Rheb affects central brain neuronal morphology and memory formation in Drosophila.

Brown HL, Kaun KR, Edgar BA.

PLoS One. 2012;7(9):e44888. doi: 10.1371/journal.pone.0044888. Epub 2012 Sep 19.

42.

Combinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters.

O'Keefe DD, Thomas SR, Bolin K, Griggs E, Edgar BA, Buttitta LA.

BMC Genomics. 2012 Sep 20;13:498. doi: 10.1186/1471-2164-13-498.

43.

Discontinuities in Rap1 activity determine epithelial cell morphology within the developing wing of Drosophila.

O'Keefe DD, Gonzalez-Niño E, Edgar BA, Curtiss J.

Dev Biol. 2012 Sep 15;369(2):223-34. doi: 10.1016/j.ydbio.2012.06.024. Epub 2012 Jul 7.

44.

Intestinal stem cell function in Drosophila and mice.

Jiang H, Edgar BA.

Curr Opin Genet Dev. 2012 Aug;22(4):354-60. doi: 10.1016/j.gde.2012.04.002. Epub 2012 May 19. Review.

45.

Intestinal stem cells: no longer immortal but ever so clever....

Edgar BA.

EMBO J. 2012 May 30;31(11):2441-3. doi: 10.1038/emboj.2012.133. Epub 2012 May 11.

46.

[Major changes in the global pharmaceutical industry].

Hedner T, Thornblad T, Edgar B, Cowlrick I, Olausson M, Lind L, Klofsten M.

Lakartidningen. 2012 Feb 15-21;109(7):324-5. Swedish. No abstract available.

PMID:
22574425
47.

LST8 regulates cell growth via target-of-rapamycin complex 2 (TORC2).

Wang T, Blumhagen R, Lao U, Kuo Y, Edgar BA.

Mol Cell Biol. 2012 Jun;32(12):2203-13. doi: 10.1128/MCB.06474-11. Epub 2012 Apr 9.

48.

Drosophila cyclin D/Cdk4 regulates mitochondrial biogenesis and aging and sensitizes animals to hypoxic stress.

Icreverzi A, de la Cruz AF, Van Voorhies WA, Edgar BA.

Cell Cycle. 2012 Feb 1;11(3):554-68. doi: 10.4161/cc.11.3.19062. Epub 2012 Feb 1.

49.

Control of Drosophila endocycles by E2F and CRL4(CDT2).

Zielke N, Kim KJ, Tran V, Shibutani ST, Bravo MJ, Nagarajan S, van Straaten M, Woods B, von Dassow G, Rottig C, Lehner CF, Grewal SS, Duronio RJ, Edgar BA.

Nature. 2011 Oct 30;480(7375):123-7. doi: 10.1038/nature10579.

50.

Intestinal stem cells in the adult Drosophila midgut.

Jiang H, Edgar BA.

Exp Cell Res. 2011 Nov 15;317(19):2780-8. doi: 10.1016/j.yexcr.2011.07.020. Epub 2011 Aug 11. Review.

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