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Items: 42

1.

Discovery and Clinical Evaluation of MK-8150, A Novel Nitric Oxide Donor With a Unique Mechanism of Nitric Oxide Release.

Knox CD, de Kam PJ, Azer K, Wong P, Ederveen AG, Shevell D, Morabito C, Meehan AG, Liu W, Reynders T, Denef JF, Mitselos A, Jonathan D, Gutstein DE, Mitra K, Sun SY, Lo MM, Cully D, Ali A.

J Am Heart Assoc. 2016 Aug 25;5(9). pii: e003493. doi: 10.1161/JAHA.116.003493.

2.

Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.

Amos-Landgraf JM, Heijmans J, Wielenga MC, Dunkin E, Krentz KJ, Clipson L, Ederveen AG, Groothuis PG, Mosselman S, Muncan V, Hommes DW, Shedlovsky A, Dove WF, van den Brink GR.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16514-9. doi: 10.1073/pnas.1323064111. Epub 2014 Nov 3.

3.

Identification of coregulators influenced by estrogen receptor subtype specific binding of the ER antagonists 4-hydroxytamoxifen and fulvestrant.

Evers NM, Wang S, van den Berg JH, Houtman R, Melchers D, de Haan LH, Ederveen AG, Groten JP, Rietjens IM.

Chem Biol Interact. 2014 Sep 5;220:222-30. doi: 10.1016/j.cbi.2014.06.019. Epub 2014 Jul 8.

PMID:
25014417
4.

Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERα and ERβ agonists.

Evers NM, van den Berg JH, Wang S, Melchers D, Houtman R, de Haan LH, Ederveen AG, Groten JP, Rietjens IM.

J Steroid Biochem Mol Biol. 2014 Sep;143:376-85. doi: 10.1016/j.jsbmb.2014.06.002. Epub 2014 Jun 9.

PMID:
24923734
5.

Correction: Intestinal Tumorigenesis Is Not Affected by Progesterone Signaling in Rodent Models.

Heijmans J, Muncan V, Jacobs RJ, de Jonge-Muller ESM, Graven L, Biemond I, Ederveen AG, Groothuis PG, Mosselman S, Hardwick JC, Hommes DW, van den Brink GR.

PLoS One. 2013 Jun 5;8(6). doi: 10.1371/annotation/b60d4ec5-4c6f-43ab-9f63-322e3cd59636. eCollection 2013.

6.

Human T47D-ERβ breast cancer cells with tetracycline-dependent ERβ expression reflect ERα/ERβ ratios in rat and human breast tissue.

Evers NM, van de Klundert TM, van Aesch YM, Wang S, de Roos WK, Romano A, de Haan LH, Murk AJ, Ederveen AG, Rietjens IM, Groten JP.

Toxicol In Vitro. 2013 Sep;27(6):1753-61. doi: 10.1016/j.tiv.2013.04.014. Epub 2013 May 13.

PMID:
23680332
7.

Opposing roles of ERα and ERβ in the genesis and progression of adenocarcinoma in the rat ventral prostate.

Attia DM, Ederveen AG.

Prostate. 2012 Jun 15;72(9):1013-22. doi: 10.1002/pros.21507. Epub 2011 Oct 24.

PMID:
22025007
8.

Intestinal tumorigenesis is not affected by progesterone signaling in rodent models.

Heijmans J, Muncan V, Jacobs RJ, de Jonge-Muller ES, Graven L, Biemond I, Ederveen AG, Groothuis PG, Mosselman S, Hardwick JC, Hommes DW, van den Brink GR.

PLoS One. 2011;6(7):e22620. doi: 10.1371/journal.pone.0022620. Epub 2011 Jul 27. Erratum in: PLoS One. 2013 Jun 5;8(6):.

9.

Development of osteoarthritic features in estrogen receptor knockout mice.

Sniekers YH, van Osch GJ, Ederveen AG, Inzunza J, Gustafsson JA, van Leeuwen JP, Weinans H.

Osteoarthritis Cartilage. 2009 Oct;17(10):1356-61. doi: 10.1016/j.joca.2009.04.008. Epub 2009 Apr 17.

10.

The estrogenic component of tibolone reduces adiposity in female aromatase knockout mice.

Van Sinderen ML, Boon WC, Ederveen AG, Kloosterboer HJ, Simpson ER, Jones ME.

Menopause. 2009 May-Jun;16(3):582-8. doi: 10.1097/gme.0b013e31818fb20b.

PMID:
19182696
11.

Follicle-stimulating hormone responses to kisspeptin in the female rat at the preovulatory period: modulation by estrogen and progesterone receptors.

Roa J, Vigo E, Castellano JM, Gaytan F, García-Galiano D, Navarro VM, Aguilar E, Dijcks FA, Ederveen AG, Pinilla L, van Noort PI, Tena-Sempere M.

Endocrinology. 2008 Nov;149(11):5783-90. doi: 10.1210/en.2008-0604. Epub 2008 Jul 17.

PMID:
18635654
12.

Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.

Roa J, Vigo E, Castellano JM, Gaytan F, Navarro VM, Aguilar E, Dijcks FA, Ederveen AG, Pinilla L, van Noort PI, Tena-Sempere M.

Endocrinology. 2008 Apr;149(4):1627-37. doi: 10.1210/en.2007-1540. Epub 2008 Jan 3.

PMID:
18174277
13.

Metabolism of tibolone and its metabolites in uterine and vaginal tissue of rat and human origin.

Blom MJ, Wassink MG, De Gooyer ME, Ederveen AG, Kloosterboer HJ, Lange J, Lambert JG, Goos HJ.

J Steroid Biochem Mol Biol. 2006 Sep;101(1):42-9. Epub 2006 Aug 7.

PMID:
16893645
14.

Tibolone and metabolites induce prolactin production in human endometrial stromal cells in vitro: evidence for cell-specific metabolism.

Groothuis PG, De Gooyer ME, ten Kate J, Menheere PP, Dunselman GA, de Goeij AF, Verbost P, Ederveen AG, Kloosterboer HJ.

J Steroid Biochem Mol Biol. 2006 Aug;100(4-5):152-60. Epub 2006 Jun 14.

PMID:
16781141
15.

Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing.

McNamara LM, Ederveen AG, Lyons CG, Price C, Schaffler MB, Weinans H, Prendergast PJ.

Bone. 2006 Aug;39(2):392-400. Epub 2006 Apr 27.

PMID:
16644297
16.

Bone loss dynamics result in trabecular alignment in aging and ovariectomized rats.

Waarsing JH, Day JS, Verhaar JA, Ederveen AG, Weinans H.

J Orthop Res. 2006 May;24(5):926-35.

17.

Effects of tibolone on bone quality in ovariectomized monkeys.

Lees CJ, Ederveen AG, Spanjers CP, Clarkson TB.

Menopause. 2005 Sep-Oct;12(5):613-8. Epub 2005 Sep 1.

PMID:
16145316
18.

Multisystem evaluations of the long-term effects of tibolone on postmenopausal monkeys.

Clarkson TB, Anthony MS, Cline JM, Lees CJ, Ederveen AG.

Maturitas. 2004 Aug 30;48 Suppl 1:S24-9.

PMID:
15337245
19.

Detecting and tracking local changes in the tibiae of individual rats: a novel method to analyse longitudinal in vivo micro-CT data.

Waarsing JH, Day JS, van der Linden JC, Ederveen AG, Spanjers C, De Clerck N, Sasov A, Verhaar JA, Weinans H.

Bone. 2004 Jan;34(1):163-9.

PMID:
14751574
20.

Intestinal calcium transporter genes are upregulated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms.

Van Cromphaut SJ, Rummens K, Stockmans I, Van Herck E, Dijcks FA, Ederveen AG, Carmeliet P, Verhaeghe J, Bouillon R, Carmeliet G.

J Bone Miner Res. 2003 Oct;18(10):1725-36.

21.
22.

Tibolone: a compound with tissue specific inhibitory effects on sulfatase.

de Gooyer ME, Kleyn GT, Smits KC, Ederveen AG, Verheul HA, Kloosterboer HJ.

Mol Cell Endocrinol. 2001 Oct 25;183(1-2):55-62.

PMID:
11604225
23.

Effect of 16 months of treatment with tibolone on bone mass, turnover, and biomechanical quality in mature ovariectomized rats.

Ederveen AG, Spanjers CP, Quaijtaal JH, Kloosterboer HJ.

J Bone Miner Res. 2001 Sep;16(9):1674-81.

24.

Tibolone exerts its protective effect on trabecular bone loss through the estrogen receptor.

Ederveen AG, Kloosterboer HJ.

J Bone Miner Res. 2001 Sep;16(9):1651-7.

25.

Testosterone prevents orchidectomy-induced bone loss in estrogen receptor-alpha knockout mice.

Vandenput L, Ederveen AG, Erben RG, Stahr K, Swinnen JV, Van Herck E, Verstuyf A, Boonen S, Bouillon R, Vanderschueren D.

Biochem Biophys Res Commun. 2001 Jul 6;285(1):70-6.

PMID:
11437374
26.

Metabolism of norethisterone and norethisterone derivatives in rat uterus, vagina, and aorta.

Blom MJ, Wassink MG, van Wijk F, Ederveen AG, Kloosterboer HJ, Verhoeven CH, Lambert JG, Goos HJ.

Drug Metab Dispos. 2001 Jul;29(7):976-82.

PMID:
11408363
27.

Metabolism of estradiol, ethynylestradiol, and moxestrol in rat uterus, vagina, and aorta: influence of sex steroid treatment.

Blom MJ, Wassink MG, Kloosterboer HJ, Ederveen AG, Lambert JG, Goos HJ.

Drug Metab Dispos. 2001 Jan;29(1):76-81.

PMID:
11124233
28.

Skeletal effects of estrogen deficiency as induced by an aromatase inhibitor in an aged male rat model.

Vanderschueren D, Boonen S, Ederveen AG, de Coster R, Van Herck E, Moermans K, Vandenput L, Verstuyf A, Bouillon R.

Bone. 2000 Nov;27(5):611-7.

PMID:
11062346
29.

Influence of exercise on bone mineral density of immature cortical and trabecular bone of the equine metacarpus and proximal sesamoid bone.

Cornelissen BP, van Weeren PR, Ederveen AG, Barneveld A.

Equine Vet J Suppl. 1999 Nov;(31):79-85.

PMID:
10999665
30.

Effects of delaying puberty on bone mineralization in female rats.

Rakover Y, Lu P, Briody JN, Tao C, Weiner E, Ederveen AG, Cowell CT, Ben-Shlomo I.

Hum Reprod. 2000 Jul;15(7):1457-61.

PMID:
10875850
31.
32.

Plasma nitrate+nitrite levels are regulated by ovarian steroids but do not correlate with trabecular bone mineral density in rats.

van Bezooijen RL, Que I, Ederveen AG, Kloosterboer HJ, Papapoulos SE, Löwik CW.

J Endocrinol. 1998 Oct;159(1):27-34.

PMID:
9795338
33.

Aromatase inhibition impairs skeletal modeling and decreases bone mineral density in growing male rats.

Vanderschueren D, van Herck E, Nijs J, Ederveen AG, De Coster R, Bouillon R.

Endocrinology. 1997 Jun;138(6):2301-7.

PMID:
9165015
34.

Accuracy and the influence of marrow fat on quantitative CT and dual-energy X-ray absorptiometry measurements of the femoral neck in vitro.

Kuiper JW, van Kuijk C, Grashuis JL, Ederveen AG, Schütte HE.

Osteoporos Int. 1996;6(1):25-30.

PMID:
8845596
35.

Oestrogen and progestogen synergistically stimulate human and rat osteoblast proliferation.

Slootweg MC, Ederveen AG, Schot LP, Schoonen WG, Kloosterboer HJ.

J Endocrinol. 1992 May;133(2):R5-8.

PMID:
1613416
36.

Purification and characterization of rabbit pancreas protein kinase C.

Ederveen AG, Van Emst-De Vries SE, Burgers LH, De Pont JJ.

Pancreas. 1992;7(1):34-44.

PMID:
1557344
37.

Effects of phorbol ester and cholecystokinin on the intracellular distribution of protein kinase C in rabbit pancreatic acini.

Ederveen AG, van Emst-de Vries SE, de Pont JJ, Willems PH.

Eur J Biochem. 1991 Feb 14;195(3):679-83.

38.
39.

The diacylglycerol kinase inhibitor, R59022, potentiates cholecystokinin-induced enzyme secretion from rabbit pancreatic acini.

Ederveen AG, van Emst-de Vries SE, De Pont JJ, Willems PH.

Eur J Biochem. 1990 Mar 10;188(2):333-8.

40.

Phosphorylation of low molecular mass cytosolic proteins by protein kinase C and protein kinase A in the rabbit exocrine pancreas.

Ederveen AG, van der Leest JV, van Emst-de Vries SE, de Pont JJ.

Eur J Biochem. 1989 Nov 6;185(2):461-8.

41.

The functional significance of glycosylation of pro-opiomelanocortin in melanotrophs of the mouse pituitary gland.

Jenks BG, Ederveen AG, Feyen JH, van Overbeeke AP.

J Endocrinol. 1985 Dec;107(3):365-74.

PMID:
2999283
42.

Lack of immunological cross reactivity between the transport enzymes (Na+ + K+)-ATPase and (K+ + H+)-ATPase.

Peters WH, Ederveen AG, Salden MH, de Pont JJ, Bonting SL.

J Bioenerg Biomembr. 1984 Jun;16(3):223-32.

PMID:
6100299

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