Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 25

1.

Cholesterol Overload: Contact Sites to the Rescue!

Enrich C, Rentero C, Grewal T, Futter CE, Eden ER.

Contact (Thousand Oaks). 2019 Jan 1;2:2515256419893507. doi: 10.1177/2515256419893507. Epub 2019 Dec 5.

2.

NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress.

Höglinger D, Burgoyne T, Sanchez-Heras E, Hartwig P, Colaco A, Newton J, Futter CE, Spiegel S, Platt FM, Eden ER.

Nat Commun. 2019 Sep 19;10(1):4276. doi: 10.1038/s41467-019-12152-2.

3.

Roles for ER:endosome membrane contact sites in ligand-stimulated intraluminal vesicle formation.

Wong LH, Eden ER, Futter CE.

Biochem Soc Trans. 2018 Oct 19;46(5):1055-1062. doi: 10.1042/BST20170432. Epub 2018 Sep 20. Review.

4.

Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers.

Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP, Iaea DB, Maxfield FR, Futter CE, Eden ER, Judith D, van Vliet AR, Agostinis P, Tooze SA, Sugiura A, McBride HM.

BMC Biol. 2017 Oct 31;15(1):102. doi: 10.1186/s12915-017-0432-0.

5.

An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling.

Kilpatrick BS, Eden ER, Hockey LN, Yates E, Futter CE, Patel S.

Cell Rep. 2017 Feb 14;18(7):1636-1645. doi: 10.1016/j.celrep.2017.01.052.

6.

Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport.

Eden ER, Sanchez-Heras E, Tsapara A, Sobota A, Levine TP, Futter CE.

Dev Cell. 2016 Jun 6;37(5):473-83. doi: 10.1016/j.devcel.2016.05.005.

7.

Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes.

Starling GP, Yip YY, Sanger A, Morton PE, Eden ER, Dodding MP.

EMBO Rep. 2016 Jun;17(6):823-41. doi: 10.15252/embr.201541382. Epub 2016 Apr 13.

8.

The formation and function of ER-endosome membrane contact sites.

Eden ER.

Biochim Biophys Acta. 2016 Aug;1861(8 Pt B):874-879. doi: 10.1016/j.bbalip.2016.01.020. Epub 2016 Feb 16. Review.

9.

Coupling acidic organelles with the ER through Ca²⁺ microdomains at membrane contact sites.

Penny CJ, Kilpatrick BS, Eden ER, Patel S.

Cell Calcium. 2015 Oct;58(4):387-96. doi: 10.1016/j.ceca.2015.03.006. Epub 2015 Mar 23. Review.

PMID:
25866010
10.

Methods for monitoring lysosomal morphology.

Kilpatrick BS, Eden ER, Hockey LN, Futter CE, Patel S.

Methods Cell Biol. 2015;126:1-19. doi: 10.1016/bs.mcb.2014.10.018. Epub 2015 Jan 19.

PMID:
25665438
11.

Calcium signaling at ER membrane contact sites.

Burgoyne T, Patel S, Eden ER.

Biochim Biophys Acta. 2015 Sep;1853(9):2012-7. doi: 10.1016/j.bbamcr.2015.01.022. Epub 2015 Feb 4. Review.

12.

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition.

Hockey LN, Kilpatrick BS, Eden ER, Lin-Moshier Y, Brailoiu GC, Brailoiu E, Futter CE, Schapira AH, Marchant JS, Patel S.

J Cell Sci. 2015 Jan 15;128(2):232-8. doi: 10.1242/jcs.164152. Epub 2014 Nov 21.

13.

EGF receptor trafficking: consequences for signaling and cancer.

Tomas A, Futter CE, Eden ER.

Trends Cell Biol. 2014 Jan;24(1):26-34. doi: 10.1016/j.tcb.2013.11.002. Epub 2013 Nov 29. Review.

14.

Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles.

Edgar JR, Eden ER, Futter CE.

Traffic. 2014 Feb;15(2):197-211. doi: 10.1111/tra.12139. Epub 2014 Jan 8.

15.

Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals.

Kilpatrick BS, Eden ER, Schapira AH, Futter CE, Patel S.

J Cell Sci. 2013 Jan 1;126(Pt 1):60-6. doi: 10.1242/jcs.118836. Epub 2012 Oct 29.

16.

The relationship between ER-multivesicular body membrane contacts and the ESCRT machinery.

Eden ER, Burgoyne T, Edgar JR, Sorkin A, Futter CE.

Biochem Soc Trans. 2012 Apr;40(2):464-8. doi: 10.1042/BST20110774. Review.

PMID:
22435831
17.

The role of EGF receptor ubiquitination in regulating its intracellular traffic.

Eden ER, Huang F, Sorkin A, Futter CE.

Traffic. 2012 Feb;13(2):329-37. doi: 10.1111/j.1600-0854.2011.01305.x. Epub 2011 Nov 22.

18.

Increased secretion of lipoproteins in transgenic mice expressing human D374Y PCSK9 under physiological genetic control.

Herbert B, Patel D, Waddington SN, Eden ER, McAleenan A, Sun XM, Soutar AK.

Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1333-9. doi: 10.1161/ATVBAHA.110.204040. Epub 2010 May 6.

PMID:
20448210
19.

Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interaction.

Eden ER, White IJ, Tsapara A, Futter CE.

Nat Cell Biol. 2010 Mar;12(3):267-72. doi: 10.1038/ncb2026. Epub 2010 Jan 31.

PMID:
20118922
20.

Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies.

Eden ER, White IJ, Futter CE.

Biochem Soc Trans. 2009 Feb;37(Pt 1):173-7. doi: 10.1042/BST0370173. Review.

PMID:
19143625
21.
22.

Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia.

Sun XM, Eden ER, Tosi I, Neuwirth CK, Wile D, Naoumova RP, Soutar AK.

Hum Mol Genet. 2005 May 1;14(9):1161-9. Epub 2005 Mar 16.

PMID:
15772090
23.

Two novel missense mutations in ABCA1 result in altered trafficking and cause severe autosomal recessive HDL deficiency.

Albrecht C, Baynes K, Sardini A, Schepelmann S, Eden ER, Davies SW, Higgins CF, Feher MD, Owen JS, Soutar AK.

Biochim Biophys Acta. 2004 May 24;1689(1):47-57.

24.

Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1.

Eden ER, Patel DD, Sun XM, Burden JJ, Themis M, Edwards M, Lee P, Neuwirth C, Naoumova RP, Soutar AK.

J Clin Invest. 2002 Dec;110(11):1695-702.

25.

Supplemental Content

Support Center