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Items: 1 to 50 of 139

1.

Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen.

Simonneau C, Yang J, Kong X, Kilker R, Edelstein L, Fortina P, Londin E, Horowitz A.

Sci Rep. 2019 Oct 2;9(1):14238. doi: 10.1038/s41598-019-50588-0.

2.

Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis.

Madan N, Ghazi AR, Kong X, Chen ES, Shaw CA, Edelstein LC.

PLoS Genet. 2019 Jul 25;15(7):e1008287. doi: 10.1371/journal.pgen.1008287. eCollection 2019 Jul.

3.

Cytoarchitecture of the dorsal claustrum of the cat: a quantitative Golgi study.

Hinova-Palova D, Kotov G, Landzhov B, Edelstein L, Iliev A, Stanchev S, Georgiev GP, Kirkov V, Angelov T, Nikolov D, Fakih K, Paloff A.

J Mol Histol. 2019 Oct;50(5):435-457. doi: 10.1007/s10735-019-09839-7. Epub 2019 Jul 13.

PMID:
31302827
4.

Horizontal RNA transfer goes deep: platelet consumption and microRNA utilization by vascular smooth muscle cells.

Goldfinger LE, Edelstein LC.

J Thromb Haemost. 2019 Jul;17(7):1014-1017. doi: 10.1111/jth.14442. No abstract available.

PMID:
31257731
5.

Ultrastructure of the dorsal claustrum in cat. II. Synaptic organization.

Hinova-Palova D, Landzhov B, Iliev A, Kotov G, Stanchev S, Kirkov V, Georgiev GP, Edelstein L, Paloff A.

Acta Histochem. 2019 May;121(4):383-391. doi: 10.1016/j.acthis.2019.02.009. Epub 2019 Mar 4.

PMID:
30846200
6.

Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood.

Bhatlekar S, Basak I, Edelstein LC, Campbell RA, Lindsey CR, Italiano JE Jr, Weyrich AS, Rowley JW, Rondina MT, Sola-Visner M, Bray PF.

Haematologica. 2019 Oct;104(10):2075-2083. doi: 10.3324/haematol.2018.204685. Epub 2019 Feb 7.

7.

Identification of the Regulatory Elements and Target Genes of Megakaryopoietic Transcription Factor MEF2C.

Kong X, Ma L, Chen E, Shaw CA, Edelstein LC.

Thromb Haemost. 2019 May;119(5):716-725. doi: 10.1055/s-0039-1678694. Epub 2019 Feb 7.

PMID:
30731491
8.

miR-15a-5p regulates expression of multiple proteins in the megakaryocyte GPVI signaling pathway.

Basak I, Bhatlekar S, Manne BK, Stoller M, Hugo S, Kong X, Ma L, Rondina MT, Weyrich AS, Edelstein LC, Bray PF.

J Thromb Haemost. 2019 Mar;17(3):511-524. doi: 10.1111/jth.14382. Epub 2019 Feb 25.

PMID:
30632265
9.

The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y12 inhibition.

Whitley MJ, Henke DM, Ghazi A, Nieman M, Stoller M, Simon LM, Chen E, Vesci J, Holinstat M, McKenzie SE, Shaw CA, Edelstein LC, Bray PF.

J Thromb Haemost. 2018 Dec;16(12):2501-2514. doi: 10.1111/jth.14318. Epub 2018 Nov 22.

10.

Electron microscopic study of Golgi-impregnated and gold-toned neurons and fibers in the claustrum of the cat.

Hinova-Palova D, Iliev A, Edelstein L, Landzhov B, Kotov G, Paloff A.

J Mol Histol. 2018 Dec;49(6):615-630. doi: 10.1007/s10735-018-9799-7. Epub 2018 Oct 10.

PMID:
30306356
11.

Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial.

Tricoci P, Neely M, Whitley MJ, Edelstein LC, Simon LM, Shaw C, Fortina P, Moliterno DJ, Armstrong PW, Aylward P, White H, Van de Werf F, Jennings LK, Wallentin L, Held C, Harrington RA, Mahaffey KW, Bray PF.

Blood Cells Mol Dis. 2018 Sep;72:37-43. doi: 10.1016/j.bcmd.2018.07.004. Epub 2018 Jul 21.

12.

Design tools for MPRA experiments.

Ghazi AR, Chen ES, Henke DM, Madan N, Edelstein LC, Shaw CA.

Bioinformatics. 2018 Aug 1;34(15):2682-2683. doi: 10.1093/bioinformatics/bty150.

13.

Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics.

Tourdot BE, Stoveken H, Trumbo D, Yeung J, Kanthi Y, Edelstein LC, Bray PF, Tall GG, Holinstat M.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1632-1643. doi: 10.1161/ATVBAHA.118.311112. Epub 2018 May 10.

14.

Comparative investigation of neuronal nitric oxide synthase immunoreactivity in rat and human claustrum.

Landzhov B, Hinova-Palova D, Edelstein L, Dzhambazova E, Brainova I, Georgiev GP, Ivanova V, Paloff A, Ovtscharoff W.

J Chem Neuroanat. 2017 Dec;86:1-14. doi: 10.1016/j.jchemneu.2017.07.003. Epub 2017 Jul 15.

PMID:
28720408
15.

Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth.

Michael JV, Wurtzel JGT, Mao GF, Rao AK, Kolpakov MA, Sabri A, Hoffman NE, Rajan S, Tomar D, Madesh M, Nieman MT, Yu J, Edelstein LC, Rowley JW, Weyrich AS, Goldfinger LE.

Blood. 2017 Aug 3;130(5):567-580. doi: 10.1182/blood-2016-11-751099. Epub 2017 May 12.

16.

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.

Kong X, Simon LM, Holinstat M, Shaw CA, Bray PF, Edelstein LC.

Thromb Haemost. 2017 May 3;117(5):962-970. doi: 10.1160/TH16-09-0692. Epub 2017 Mar 2.

17.

The role of platelet microvesicles in intercellular communication.

Edelstein LC.

Platelets. 2017 May;28(3):222-227. doi: 10.1080/09537104.2016.1257114. Epub 2016 Dec 8. Review.

PMID:
27928930
18.

TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (FcγRIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice.

Zhou Y, Abraham S, Renna S, Edelstein LC, Dangelmaier CA, Tsygankov AY, Kunapuli SP, Bray PF, McKenzie SE.

Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2315-2323. Epub 2016 Oct 20.

PMID:
27765766
19.

NADPH-diaphorase-positive neurons in the human inferior colliculus: morphology, distribution and clinical implications.

Hinova-Palova D, Landzhov B, Dzhambazova E, Edelstein L, Minkov M, Fakih K, Minkov R, Paloff A, Ovtscharoff W.

Brain Struct Funct. 2017 May;222(4):1829-1846. doi: 10.1007/s00429-016-1310-1. Epub 2016 Sep 19.

PMID:
27646398
20.

Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.

Simon LM, Chen ES, Edelstein LC, Kong X, Bhatlekar S, Rigoutsos I, Bray PF, Shaw CA.

Am J Hum Genet. 2016 May 5;98(5):883-897. doi: 10.1016/j.ajhg.2016.03.007. Epub 2016 Apr 28.

21.

Telocytes in their context with other intercellular communication agents.

Edelstein L, Fuxe K, Levin M, Popescu BO, Smythies J.

Semin Cell Dev Biol. 2016 Jul;55:9-13. doi: 10.1016/j.semcdb.2016.03.010. Epub 2016 Mar 21. Review.

PMID:
27013113
22.

MicroRNAs in Platelet Physiology and Function.

Lindsay CR, Edelstein LC.

Semin Thromb Hemost. 2016 Apr;42(3):215-22. doi: 10.1055/s-0035-1570077. Epub 2016 Mar 7. Review.

PMID:
26951501
23.

Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice.

Zhou Y, Abraham S, Andre P, Edelstein LC, Shaw CA, Dangelmaier CA, Tsygankov AY, Kunapuli SP, Bray PF, McKenzie SE.

Blood. 2015 Dec 24;126(26):2871-81. doi: 10.1182/blood-2015-02-631135. Epub 2015 Oct 29.

24.

Calretinin immunoreactivity in the claustrum of the rat.

Druga R, Salaj M, Barinka F, Edelstein L, Kubová H.

Front Neuroanat. 2015 Jan 20;8:160. doi: 10.3389/fnana.2014.00160. eCollection 2014.

25.

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race.

Edelstein LC, Simon LM, Lindsay CR, Kong X, Teruel-Montoya R, Tourdot BE, Chen ES, Ma L, Coughlin S, Nieman M, Holinstat M, Shaw CA, Bray PF.

Blood. 2014 Nov 27;124(23):3450-8. doi: 10.1182/blood-2014-04-572479. Epub 2014 Oct 7.

26.

Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis.

Tourdot BE, Conaway S, Niisuke K, Edelstein LC, Bray PF, Holinstat M.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2644-50. doi: 10.1161/ATVBAHA.114.304249. Epub 2014 Oct 2.

27.

Neuropeptide Y immunoreactivity in the cat claustrum: A light- and electron-microscopic investigation.

Hinova-Palova DV, Landzhov B, Dzhambazova E, Minkov M, Edelstein L, Malinova L, Paloff A, Ovtscharoff W.

J Chem Neuroanat. 2014 Nov;61-62:107-19. doi: 10.1016/j.jchemneu.2014.08.007. Epub 2014 Aug 23.

PMID:
25157673
28.

The desferrioxamine-prochlorperazine coma-clue to the role of dopamine-iron recycling in the synthesis of hydrogen peroxide in the brain.

Smythies J, Edelstein L.

Front Mol Neurosci. 2014 Aug 4;7:74. doi: 10.3389/fnmol.2014.00074. eCollection 2014. No abstract available.

29.

The role of epigenetic-related codes in neurocomputation: dynamic hardware in the brain.

Edelstein L, Smythies J.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 26;369(1652). pii: 20130519. doi: 10.1098/rstb.2013.0519. Review.

30.

Introduction.

Edelstein L, Smythies J, Noble D.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 26;369(1652). pii: 20130501. doi: 10.1098/rstb.2013.0501. No abstract available.

31.

MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression.

Teruel-Montoya R, Kong X, Abraham S, Ma L, Kunapuli SP, Holinstat M, Shaw CA, McKenzie SE, Edelstein LC, Bray PF.

PLoS One. 2014 Jul 16;9(7):e102259. doi: 10.1371/journal.pone.0102259. eCollection 2014.

32.

Topographical distribution and morphology of NADPH-diaphorase-stained neurons in the human claustrum.

Hinova-Palova DV, Edelstein L, Landzhov B, Minkov M, Malinova L, Hristov S, Denaro FJ, Alexandrov A, Kiriakova T, Brainova I, Paloff A, Ovtscharoff W.

Front Syst Neurosci. 2014 May 27;8:96. doi: 10.3389/fnsys.2014.00096. eCollection 2014.

33.

Molecular mechanisms for the inheritance of acquired characteristics-exosomes, microRNA shuttling, fear and stress: Lamarck resurrected?

Smythies J, Edelstein L, Ramachandran V.

Front Genet. 2014 May 15;5:133. doi: 10.3389/fgene.2014.00133. eCollection 2014. No abstract available.

34.

The role of telocytes in morphogenetic bioelectrical signaling: once more unto the breach.

Edelstein L, Smythies J.

Front Mol Neurosci. 2014 May 13;7:41. doi: 10.3389/fnmol.2014.00041. eCollection 2014. No abstract available.

35.

Life without glutamate: the epigenetic effects of glutamate deletion.

Edelstein L, Fuxe K, Smythies J.

Front Mol Neurosci. 2014 Feb 26;7:14. doi: 10.3389/fnmol.2014.00014. eCollection 2014. No abstract available.

36.

Epigenetic aspects of telocytes/cordocytes: jacks of all trades, masters of most.

Edelstein L, Smythies J.

Front Cell Neurosci. 2014 Feb 10;8:32. doi: 10.3389/fncel.2014.00032. eCollection 2014. No abstract available.

37.

The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome.

Londin ER, Hatzimichael E, Loher P, Edelstein L, Shaw C, Delgrosso K, Fortina P, Bray PF, McKenzie SE, Rigoutsos I.

Biol Direct. 2014 Feb 14;9:3. doi: 10.1186/1745-6150-9-3.

38.

Hypotheses relating to the function of the claustrum II: does the claustrum use frequency codes?

Smythies J, Edelstein L, Ramachandran V.

Front Integr Neurosci. 2014 Jan 29;8:7. doi: 10.3389/fnint.2014.00007. eCollection 2014. No abstract available.

39.

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics.

Simon LM, Edelstein LC, Nagalla S, Woodley AB, Chen ES, Kong X, Ma L, Fortina P, Kunapuli S, Holinstat M, McKenzie SE, Dong JF, Shaw CA, Bray PF.

Blood. 2014 Apr 17;123(16):e37-45. doi: 10.1182/blood-2013-12-544692. Epub 2014 Feb 12.

40.

Telocytes, exosomes, gap junctions and the cytoskeleton: the makings of a primitive nervous system?

Smythies J, Edelstein L.

Front Cell Neurosci. 2014 Jan 3;7:278. doi: 10.3389/fncel.2013.00278. eCollection 2014. No abstract available.

41.

Hypotheses concerning how Otx2 makes its incredible journey: a hitchhiker on the road to Rome?

Edelstein L, Smythies J.

Front Mol Neurosci. 2013 Dec 30;6:55. doi: 10.3389/fnmol.2013.00055. eCollection 2013. No abstract available.

42.

Rat rotator cuff tendon-to-bone healing properties are adversely affected by hypercholesterolemia.

Beason DP, Tucker JJ, Lee CS, Edelstein L, Abboud JA, Soslowsky LJ.

J Shoulder Elbow Surg. 2014 Jun;23(6):867-72. doi: 10.1016/j.jse.2013.08.018. Epub 2013 Dec 2.

43.

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c.

Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen ES, Bergeron A, Kong X, Nagalla S, Mohandas N, Cohen DE, Dong JF, Shaw C, Bray PF.

Nat Med. 2013 Dec;19(12):1609-16. doi: 10.1038/nm.3385. Epub 2013 Nov 10.

44.

MicroRNAs in platelet production and activation.

Edelstein LC, McKenzie SE, Shaw C, Holinstat MA, Kunapuli SP, Bray PF.

J Thromb Haemost. 2013 Jun;11 Suppl 1:340-50. doi: 10.1111/jth.12214. Review.

45.

Interactions between the spike code and the epigenetic code during information processing in the brain.

Smythies J, Edelstein L.

Front Mol Neurosci. 2013 Jul 8;6:17. doi: 10.3389/fnmol.2013.00017. eCollection 2013. No abstract available.

46.

Parvalbumin-immunoreactive neurons in the human claustrum.

Hinova-Palova DV, Edelstein L, Landzhov BV, Braak E, Malinova LG, Minkov M, Paloff A, Ovtscharoff W.

Brain Struct Funct. 2014 Sep;219(5):1813-30. doi: 10.1007/s00429-013-0603-x. Epub 2013 Jul 6.

PMID:
23832597
47.

Spike dynamic and epigenetic malfunctions in epilepsy: a tale of two codes.

Smythies J, Edelstein L.

Front Neurol. 2013 May 27;4:63. doi: 10.3389/fneur.2013.00063. eCollection 2013. No abstract available.

48.

The complex transcriptional landscape of the anucleate human platelet.

Bray PF, McKenzie SE, Edelstein LC, Nagalla S, Delgrosso K, Ertel A, Kupper J, Jing Y, Londin E, Loher P, Chen HW, Fortina P, Rigoutsos I.

BMC Genomics. 2013 Jan 16;14:1. doi: 10.1186/1471-2164-14-1.

49.

Transsynaptic modality codes in the brain: possible involvement of synchronized spike timing, microRNAs, exosomes and epigenetic processes.

Smythies J, Edelstein L.

Front Integr Neurosci. 2013 Jan 4;6:126. doi: 10.3389/fnint.2012.00126. eCollection 2012.

50.

Light and electron-microscopic study of leucine enkephalin immunoreactivity in the cat claustrum.

Hinova-Palova D, Edelstein L, Papantchev V, Landzhov B, Malinova L, Todorova-Papantcheva D, Minkov M, Paloff A, Ovtscharoff W.

J Mol Histol. 2012 Dec;43(6):641-9. doi: 10.1007/s10735-012-9448-5. Epub 2012 Sep 13.

PMID:
22972434

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