Sort by
Items per page

Send to

Choose Destination

Search results

Items: 23


Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes.

Fox JM, Roy V, Gunn BM, Huang L, Edeling MA, Mack M, Fremont DH, Doranz BJ, Johnson S, Alter G, Diamond MS.

Sci Immunol. 2019 Feb 22;4(32). pii: eaav5062. doi: 10.1126/sciimmunol.aav5062.


Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus.

Fernandez E, Kose N, Edeling MA, Adhikari J, Sapparapu G, Lazarte SM, Nelson CA, Govero J, Gross ML, Fremont DH, Crowe JE Jr, Diamond MS.

MBio. 2018 Feb 27;9(1). pii: e00008-18. doi: 10.1128/mBio.00008-18.


Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor.

Barrow AD, Edeling MA, Trifonov V, Luo J, Goyal P, Bohl B, Bando JK, Kim AH, Walker J, Andahazy M, Bugatti M, Melocchi L, Vermi W, Fremont DH, Cox S, Cella M, Schmedt C, Colonna M.

Cell. 2018 Jan 25;172(3):534-548.e19. doi: 10.1016/j.cell.2017.11.037. Epub 2017 Dec 21.


Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE Jr, Fremont DH, Rossmann MG, Diamond MS.

Cell. 2015 Nov 19;163(5):1095-1107. doi: 10.1016/j.cell.2015.10.050. Epub 2015 Nov 6.


Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement.

Edeling MA, Austin SK, Shrestha B, Dowd KA, Mukherjee S, Nelson CA, Johnson S, Mabila MN, Christian EA, Rucker J, Pierson TC, Diamond MS, Fremont DH.

PLoS Pathog. 2014 Apr 17;10(4):e1004072. doi: 10.1371/journal.ppat.1004072. eCollection 2014 Apr.


Structural basis of Flavivirus NS1 assembly and antibody recognition.

Edeling MA, Diamond MS, Fremont DH.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4285-90. doi: 10.1073/pnas.1322036111. Epub 2014 Mar 4.


The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states.

Lee PD, Mukherjee S, Edeling MA, Dowd KA, Austin SK, Manhart CJ, Diamond MS, Fremont DH, Pierson TC.

J Virol. 2013 Dec;87(24):13729-40. doi: 10.1128/JVI.02340-13. Epub 2013 Oct 9.


Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus.

Pal P, Dowd KA, Brien JD, Edeling MA, Gorlatov S, Johnson S, Lee I, Akahata W, Nabel GJ, Richter MK, Smit JM, Fremont DH, Pierson TC, Heise MT, Diamond MS.

PLoS Pathog. 2013;9(4):e1003312. doi: 10.1371/journal.ppat.1003312. Epub 2013 Apr 18.


Molecular basis for recognition of dilysine trafficking motifs by COPI.

Jackson LP, Lewis M, Kent HM, Edeling MA, Evans PR, Duden R, Owen DJ.

Dev Cell. 2012 Dec 11;23(6):1255-62. doi: 10.1016/j.devcel.2012.10.017. Epub 2012 Nov 21.


Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope.

Austin SK, Dowd KA, Shrestha B, Nelson CA, Edeling MA, Johnson S, Pierson TC, Diamond MS, Fremont DH.

PLoS Pathog. 2012;8(10):e1002930. doi: 10.1371/journal.ppat.1002930. Epub 2012 Oct 4.


Evidence for a genetic and physical interaction between nonstructural proteins NS1 and NS4B that modulates replication of West Nile virus.

Youn S, Li T, McCune BT, Edeling MA, Fremont DH, Cristea IM, Diamond MS.

J Virol. 2012 Jul;86(13):7360-71. doi: 10.1128/JVI.00157-12. Epub 2012 May 2.


The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1.

Shrestha B, Brien JD, Sukupolvi-Petty S, Austin SK, Edeling MA, Kim T, O'Brien KM, Nelson CA, Johnson S, Fremont DH, Diamond MS.

PLoS Pathog. 2010 Apr 1;6(4):e1000823. doi: 10.1371/journal.ppat.1000823.


Structural requirements for PACSIN/Syndapin operation during zebrafish embryonic notochord development.

Edeling MA, Sanker S, Shima T, Umasankar PK, Höning S, Kim HY, Davidson LA, Watkins SC, Tsang M, Owen DJ, Traub LM.

PLoS One. 2009 Dec 3;4(12):e8150. doi: 10.1371/journal.pone.0008150.


Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb.

Pryor PR, Jackson L, Gray SR, Edeling MA, Thompson A, Sanderson CM, Evans PR, Owen DJ, Luzio JP.

Cell. 2008 Sep 5;134(5):817-27. doi: 10.1016/j.cell.2008.07.023.


Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly.

Edeling MA, Mishra SK, Keyel PA, Steinhauser AL, Collins BM, Roth R, Heuser JE, Owen DJ, Traub LM.

Dev Cell. 2006 Mar;10(3):329-42.


Life of a clathrin coat: insights from clathrin and AP structures.

Edeling MA, Smith C, Owen D.

Nat Rev Mol Cell Biol. 2006 Jan;7(1):32-44. Review.


Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.

Bowers K, Piper SC, Edeling MA, Gray SR, Owen DJ, Lehner PJ, Luzio JP.

J Biol Chem. 2006 Feb 24;281(8):5094-105. Epub 2005 Dec 20.


Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein.

Mishra SK, Keyel PA, Edeling MA, Dupin AL, Owen DJ, Traub LM.

J Biol Chem. 2005 May 13;280(19):19270-80. Epub 2005 Feb 22.


Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide.

Heras B, Edeling MA, Schirra HJ, Raina S, Martin JL.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8876-81. Epub 2004 Jun 7.


The acidic nature of the CcmG redox-active center is important for cytochrome c maturation in Escherichia coli.

Edeling MA, Ahuja U, Heras B, Thöny-Meyer L, Martin JL.

J Bacteriol. 2004 Jun;186(12):4030-3.


Dehydration converts DsbG crystal diffraction from low to high resolution.

Heras B, Edeling MA, Byriel KA, Jones A, Raina S, Martin JL.

Structure. 2003 Feb;11(2):139-45.


Structure of CcmG/DsbE at 1.14 A resolution: high-fidelity reducing activity in an indiscriminately oxidizing environment.

Edeling MA, Guddat LW, Fabianek RA, Thöny-Meyer L, Martin JL.

Structure. 2002 Jul;10(7):973-9.


Crystallization and preliminary diffraction studies of native and selenomethionine CcmG (CycY, DsbE).

Edeling MA, Guddat LW, Fabianek RA, Halliday JA, Jones A, Thöny-Meyer L, Martin JL.

Acta Crystallogr D Biol Crystallogr. 2001 Sep;57(Pt 9):1293-5. Epub 2001 Aug 23.


Supplemental Content

Loading ...
Support Center