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Hyperpolarized Helium 3 MRI in Mild-to-Moderate Asthma: Prediction of Postbronchodilator Reversibility.

Eddy RL, Svenningsen S, Licskai C, McCormack DG, Parraga G.

Radiology. 2019 Oct;293(1):212-220. doi: 10.1148/radiol.2019190420. Epub 2019 Aug 6.


Normalisation of MRI ventilation heterogeneity in severe asthma by dupilumab.

Svenningsen S, Haider EA, Eddy RL, Parraga G, Nair P.

Thorax. 2019 Nov;74(11):1087-1088. doi: 10.1136/thoraxjnl-2019-213415. Epub 2019 Jul 8. No abstract available.


CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma.

Svenningsen S, Haider E, Boylan C, Mukherjee M, Eddy RL, Capaldi DPI, Parraga G, Nair P.

Chest. 2019 Jun;155(6):1178-1189. doi: 10.1016/j.chest.2019.02.403. Epub 2019 Mar 23.


Optimizing leading edge F-actin labeling using multiple actin probes, fixation methods and imaging modalities.

DesMarais V, Eddy RJ, Sharma VP, Stone O, Condeelis JS.

Biotechniques. 2019 Mar;66(3):113-119. doi: 10.2144/btn-2018-0112.


Oscillometry and pulmonary magnetic resonance imaging in asthma and COPD.

Eddy RL, Westcott A, Maksym GN, Parraga G, Dandurand RJ.

Physiol Rep. 2019 Jan;7(1):e13955. doi: 10.14814/phy2.13955.


An Academia-Industry Partnership for Planning and Executing a Community-Based Feeding Study.

Wong JM, Bielak L, Eddy RG, Stone L, Lakin PR, Sandman M, Devlin C, Seger-Shippee L, Wiroll D, Luoto PK, Klein GL, Ludwig DS, Ebbeling CB.

Curr Dev Nutr. 2018 Jul 5;2(9):nzy060. doi: 10.1093/cdn/nzy060. eCollection 2018 Sep.


What is the minimal clinically important difference for helium-3 magnetic resonance imaging ventilation defects?

Eddy RL, Svenningsen S, McCormack DG, Parraga G.

Eur Respir J. 2018 Jun 28;51(6). pii: 1800324. doi: 10.1183/13993003.00324-2018. Print 2018 Jun. No abstract available.


Test-Retest Reliability and the Effects of Exercise on the King-Devick Test.

Eddy R, Goetschius J, Hertel J, Resch J.

Clin J Sport Med. 2018 Mar 26. doi: 10.1097/JSM.0000000000000586. [Epub ahead of print]


Oscillometry and pulmonary MRI measurements of ventilation heterogeneity in obstructive lung disease: relationship to quality of life and disease control.

Young HM, Guo F, Eddy RL, Maksym G, Parraga G.

J Appl Physiol (1985). 2018 Jul 1;125(1):73-85. doi: 10.1152/japplphysiol.01031.2017. Epub 2018 Mar 15.


Free-breathing Pulmonary MR Imaging to Quantify Regional Ventilation.

Capaldi DPI, Eddy RL, Svenningsen S, Guo F, Baxter JSH, McLeod AJ, Nair P, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Radiology. 2018 May;287(2):693-704. doi: 10.1148/radiol.2018171993. Epub 2018 Feb 22.


Sputum Eosinophilia and Magnetic Resonance Imaging Ventilation Heterogeneity in Severe Asthma.

Svenningsen S, Eddy RL, Lim HF, Cox PG, Nair P, Parraga G.

Am J Respir Crit Care Med. 2018 Apr 1;197(7):876-884. doi: 10.1164/rccm.201709-1948OC.


A randomized study of dietary composition during weight-loss maintenance: Rationale, study design, intervention, and assessment.

Ebbeling CB, Klein GL, Luoto PK, Wong JMW, Bielak L, Eddy RG, Steltz SK, Devlin C, Sandman M, Hron B, Shimy K, Heymsfield SB, Wolfe RR, Wong WW, Feldman HA, Ludwig DS.

Contemp Clin Trials. 2018 Feb;65:76-86. doi: 10.1016/j.cct.2017.12.004. Epub 2017 Dec 9.


MRI and CT lung biomarkers: Towards an in vivo understanding of lung biomechanics.

Young HM, Eddy RL, Parraga G.

Clin Biomech (Bristol, Avon). 2019 Jun;66:107-122. doi: 10.1016/j.clinbiomech.2017.09.016. Epub 2017 Sep 29.


Free-breathing Functional Pulmonary MRI: Response to Bronchodilator and Bronchoprovocation in Severe Asthma.

Capaldi DPI, Sheikh K, Eddy RL, Guo F, Svenningsen S, Nair P, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Acad Radiol. 2017 Oct;24(10):1268-1276. doi: 10.1016/j.acra.2017.04.012. Epub 2017 May 24.


Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis.

Eddy RJ, Weidmann MD, Sharma VP, Condeelis JS.

Trends Cell Biol. 2017 Aug;27(8):595-607. doi: 10.1016/j.tcb.2017.03.003. Epub 2017 Apr 12. Review.


MRI ventilation abnormalities predict quality-of-life and lung function changes in mild-to-moderate COPD: longitudinal TINCan study.

Kirby M, Eddy RL, Pike D, Svenningsen S, Coxson HO, Sin DD, McCormack DG, Parraga G; Canadian Respiratory Research Network.

Thorax. 2017 May;72(5):475-477. doi: 10.1136/thoraxjnl-2016-209770. Epub 2017 Mar 3.


Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.

Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS.

Sci Rep. 2016 Nov 30;6:37874. doi: 10.1038/srep37874.


Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway.

Leung E, Xue A, Wang Y, Rougerie P, Sharma VP, Eddy R, Cox D, Condeelis J.

Oncogene. 2017 May 11;36(19):2680-2692. doi: 10.1038/onc.2016.421. Epub 2016 Nov 28.


MenaINV dysregulates cortactin phosphorylation to promote invadopodium maturation.

Weidmann MD, Surve CR, Eddy RJ, Chen X, Gertler FB, Sharma VP, Condeelis JS.

Sci Rep. 2016 Nov 8;6:36142. doi: 10.1038/srep36142.


Ultrashort echo time MRI biomarkers of asthma.

Sheikh K, Guo F, Capaldi DP, Ouriadov A, Eddy RL, Svenningsen S, Parraga G; Canadian Respiratory Research Network.

J Magn Reson Imaging. 2017 Apr;45(4):1204-1215. doi: 10.1002/jmri.25503. Epub 2016 Oct 12.


Anatomical pulmonary magnetic resonance imaging segmentation for regional structure-function measurements of asthma.

Guo F, Svenningsen S, Eddy RL, Capaldi DPI, Sheikh K, Fenster A, Parraga G.

Med Phys. 2016 Jun;43(6):2911-2926. doi: 10.1118/1.4948999.


Regional Heterogeneity of Chronic Obstructive Pulmonary Disease Phenotypes: Pulmonary (3)He Magnetic Resonance Imaging and Computed Tomography.

Pike D, Kirby M, Eddy RL, Guo F, Capaldi DP, Ouriadov A, McCormack DG, Parraga G.

COPD. 2016 Oct;13(5):601-9. doi: 10.3109/15412555.2015.1123682. Epub 2016 Jan 20.


Response to Letter on Appropriateness.

Eddy K, Eddy R, Mathieson J.

Can Assoc Radiol J. 2015 Nov;66(4):395-6. doi: 10.1016/j.carj.2015.09.010. No abstract available.


PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.

Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442. Epub 2015 Sep 2.


ACR Select Identifies Inappropriate Underutilization of Magnetic Resonance Imaging in British Columbia.

Eddy K, Beaton A, Eddy R, Mathieson J.

Can Assoc Radiol J. 2015 Aug;66(3):208-11. doi: 10.1016/j.carj.2014.12.009. Epub 2015 Jun 12.


An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction.

Sharma VP, Beaty BT, Cox D, Condeelis JS, Eddy RJ.

Methods Mol Biol. 2014;1172:115-23. doi: 10.1007/978-1-4939-0928-5_10.


Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells.

Sharma VP, Eddy R, Entenberg D, Kai M, Gertler FB, Condeelis J.

Curr Biol. 2013 Nov 4;23(21):2079-89. doi: 10.1016/j.cub.2013.08.044. Epub 2013 Oct 24.


Functions of cofilin in cell locomotion and invasion.

Bravo-Cordero JJ, Magalhaes MA, Eddy RJ, Hodgson L, Condeelis J.

Nat Rev Mol Cell Biol. 2013 Jul;14(7):405-15. doi: 10.1038/nrm3609. Epub 2013 Jun 19. Review.


Spatial regulation of RhoC activity defines protrusion formation in migrating cells.

Bravo-Cordero JJ, Sharma VP, Roh-Johnson M, Chen X, Eddy R, Condeelis J, Hodgson L.

J Cell Sci. 2013 Aug 1;126(Pt 15):3356-69. doi: 10.1242/jcs.123547. Epub 2013 May 23.


β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.

Beaty BT, Sharma VP, Bravo-Cordero JJ, Simpson MA, Eddy RJ, Koleske AJ, Condeelis J.

Mol Biol Cell. 2013 Jun;24(11):1661-75, S1-11. doi: 10.1091/mbc.E12-12-0908. Epub 2013 Apr 3.


Reconstitution of in vivo macrophage-tumor cell pairing and streaming motility on one-dimensional micro-patterned substrates.

Sharma VP, Beaty BT, Patsialou A, Liu H, Clarke M, Cox D, Condeelis JS, Eddy RJ.

Intravital. 2012 Jul 1;1(1):77-85.


The "safe" triangle, contrast material, and particulate steroids in lumbar transforaminal injections: What are the right things to do?

Hilton JD, Eddy R, Connell D.

Clin Radiol. 2012 Jul;67(7):619-22. doi: 10.1016/j.crad.2012.02.001. Epub 2012 Apr 6. No abstract available.


Vasitis: clinical and ultrasound confusion with inguinal hernia clarified by computed tomography.

Eddy K, Piercy GB, Eddy R.

Can Urol Assoc J. 2011 Aug;5(4):E74-6. doi: 10.5489/cuaj.10116.


A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.

Bravo-Cordero JJ, Oser M, Chen X, Eddy R, Hodgson L, Condeelis J.

Curr Biol. 2011 Apr 26;21(8):635-44. doi: 10.1016/j.cub.2011.03.039. Epub 2011 Apr 7.


Imaging findings prevent unnecessary surgery in vasitis: an under-reported condition mimicking inguinal hernia.

Eddy K, Connell D, Goodacre B, Eddy R.

Clin Radiol. 2011 May;66(5):475-7. doi: 10.1016/j.crad.2010.12.006. No abstract available.


Bowel preparation suitable for same-day computed tomography colonography and colonoscopy.

Eddy M, Stevenson G, Mathieson J, Behrens C, Eddy R.

Can Assoc Radiol J. 2011 Nov;62(4):256-9. doi: 10.1016/j.carj.2010.05.003. Epub 2010 Jul 9.


Bowel preparation regimen for computed tomography colonography.

Behrens C, Eddy R, Stevenson G, Audet L, Mathieson J.

Can Assoc Radiol J. 2010 Dec;61(5):280-5. doi: 10.1016/j.carj.2009.12.008. Epub 2010 Mar 2.


The benefits of computed tomographic colonography in reducing a long colonoscopy waiting list.

Behrens C, Stevenson G, Eddy R, Pearson D, Hayashi A, Audet L, Mathieson J.

Can Assoc Radiol J. 2010 Feb;61(1):33-40; quiz 2. doi: 10.1016/j.carj.2009.09.003. Epub 2009 Dec 10.


Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering.

Leyman S, Sidani M, Ritsma L, Waterschoot D, Eddy R, Dewitte D, Debeir O, Decaestecker C, Vandekerckhove J, van Rheenen J, Ampe C, Condeelis J, Van Troys M.

Mol Biol Cell. 2009 Nov;20(21):4509-23. doi: 10.1091/mbc.E09-02-0121. Epub 2009 Sep 9.


N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells.

Desmarais V, Yamaguchi H, Oser M, Soon L, Mouneimne G, Sarmiento C, Eddy R, Condeelis J.

Cell Motil Cytoskeleton. 2009 Jun;66(6):303-16. doi: 10.1002/cm.20361.


Tuberculous epididymitis following intravesical Bacillus Calmette-Guérin immunotherapy.

Hoag N, Pommerville PJ, Kibsey PC, Cavers DJ, Eddy RJ.

Can J Urol. 2009 Apr;16(2):4589-91.


Effect of intravenous Buscopan on colonic distention during computed tomography colonography.

Behrens C, Stevenson G, Eddy R, Mathieson J.

Can Assoc Radiol J. 2008 Oct;59(4):183-90.


Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding.

Frantz C, Barreiro G, Dominguez L, Chen X, Eddy R, Condeelis J, Kelly MJ, Jacobson MP, Barber DL.

J Cell Biol. 2008 Dec 1;183(5):865-79. doi: 10.1083/jcb.200804161. Epub 2008 Nov 24.


Quantification of PtdIns(3,4,5)P(3) dynamics in EGF-stimulated carcinoma cells: a comparison of PH-domain-mediated methods with immunological methods.

Yip SC, Eddy RJ, Branch AM, Pang H, Wu H, Yan Y, Drees BE, Neilsen PO, Condeelis J, Backer JM.

Biochem J. 2008 Apr 15;411(2):441-8. doi: 10.1042/BJ20071179.


EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells.

van Rheenen J, Song X, van Roosmalen W, Cammer M, Chen X, Desmarais V, Yip SC, Backer JM, Eddy RJ, Condeelis JS.

J Cell Biol. 2007 Dec 17;179(6):1247-59.


Cofilin determines the migration behavior and turning frequency of metastatic cancer cells.

Sidani M, Wessels D, Mouneimne G, Ghosh M, Goswami S, Sarmiento C, Wang W, Kuhl S, El-Sibai M, Backer JM, Eddy R, Soll D, Condeelis J.

J Cell Biol. 2007 Nov 19;179(4):777-91.


The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration.

Yip SC, El-Sibai M, Coniglio SJ, Mouneimne G, Eddy RJ, Drees BE, Neilsen PO, Goswami S, Symons M, Condeelis JS, Backer JM.

J Cell Sci. 2007 Sep 1;120(Pt 17):3138-46. Epub 2007 Aug 14.


The cofilin pathway in breast cancer invasion and metastasis.

Wang W, Eddy R, Condeelis J.

Nat Rev Cancer. 2007 Jun;7(6):429-40. Review.


Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis.

Mouneimne G, DesMarais V, Sidani M, Scemes E, Wang W, Song X, Eddy R, Condeelis J.

Curr Biol. 2006 Nov 21;16(22):2193-205.


Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells.

Song X, Chen X, Yamaguchi H, Mouneimne G, Condeelis JS, Eddy RJ.

J Cell Sci. 2006 Jul 15;119(Pt 14):2871-81. Epub 2006 Jun 27.

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