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Items: 1 to 20 of 110

1.

Mitochondrial Pharmacology of Dimebon (Latrepirdine) Calls for a New Look at its Possible Therapeutic Potential in Alzheimer's Disease.

Eckert SH, Gaca J, Kolesova N, Friedland K, Eckert GP, Muller WE.

Aging Dis. 2018 Aug 1;9(4):729-744. doi: 10.14336/AD.2017.1014. eCollection 2018 Aug. Review.

2.

Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain.

Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP.

Biol Sex Differ. 2018 Jul 25;9(1):34. doi: 10.1186/s13293-018-0193-7.

3.

Mitochondrial Function, Dynamics, and Permeability Transition: A Complex Love Triangle as A Possible Target for the Treatment of Brain Aging and Alzheimer's Disease.

Stockburger C, Eckert S, Eckert GP, Friedland K, Müller WE.

J Alzheimers Dis. 2018;64(s1):S455-S467. doi: 10.3233/JAD-179915.

PMID:
29504539
4.

MH84 improves mitochondrial dysfunction in a mouse model of early Alzheimer's disease.

Pohland M, Pellowska M, Asseburg H, Hagl S, Reutzel M, Joppe A, Berressem D, Eckert SH, Wurglics M, Schubert-Zsilavecz M, Eckert GP.

Alzheimers Res Ther. 2018 Feb 13;10(1):18. doi: 10.1186/s13195-018-0342-6.

5.

Peptidomimetics That Inhibit and Partially Reverse the Aggregation of Aβ1-42.

Stark T, Lieblein T, Pohland M, Kalden E, Freund P, Zangl R, Grewal R, Heilemann M, Eckert GP, Morgner N, Göbel MW.

Biochemistry. 2017 Sep 12;56(36):4840-4849. doi: 10.1021/acs.biochem.7b00223. Epub 2017 Aug 25.

PMID:
28841311
6.

A diet rich in omega-3 fatty acids enhances expression of soluble epoxide hydrolase in murine brain.

Ostermann AI, Reutzel M, Hartung N, Franke N, Kutzner L, Schoenfeld K, Weylandt KH, Eckert GP, Schebb NH.

Prostaglandins Other Lipid Mediat. 2017 Nov;133:79-87. doi: 10.1016/j.prostaglandins.2017.06.001. Epub 2017 Jun 3.

PMID:
28583889
7.

Therapeutic efficacy of the Ginkgo special extract EGb761® within the framework of the mitochondrial cascade hypothesis of Alzheimer's disease.

Müller WE, Eckert A, Eckert GP, Fink H, Friedland K, Gauthier S, Hoerr R, Ihl R, Kasper S, Möller HJ.

World J Biol Psychiatry. 2017 May 2:1-17. doi: 10.1080/15622975.2017.1308552. [Epub ahead of print]

PMID:
28460580
8.

Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice.

Koch K, Berressem D, Konietzka J, Thinnes A, Eckert GP, Klein J.

J Am Heart Assoc. 2017 Apr 5;6(4). pii: e005556. doi: 10.1161/JAHA.117.005556.

9.

Intravenous Treatment with a Long-Chain Omega-3 Lipid Emulsion Provides Neuroprotection in a Murine Model of Ischemic Stroke - A Pilot Study.

Berressem D, Koch K, Franke N, Klein J, Eckert GP.

PLoS One. 2016 Nov 30;11(11):e0167329. doi: 10.1371/journal.pone.0167329. eCollection 2016.

10.

Effects of Grape Skin Extract on Age-Related Mitochondrial Dysfunction, Memory and Life Span in C57BL/6J Mice.

Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP.

Neuromolecular Med. 2016 Sep;18(3):378-95. doi: 10.1007/s12017-016-8428-4. Epub 2016 Jul 25.

PMID:
27455862
11.

Effects of Long-Term Rice Bran Extract Supplementation on Survival, Cognition and Brain Mitochondrial Function in Aged NMRI Mice.

Hagl S, Asseburg H, Heinrich M, Sus N, Blumrich EM, Dringen R, Frank J, Eckert GP.

Neuromolecular Med. 2016 Sep;18(3):347-63. doi: 10.1007/s12017-016-8420-z. Epub 2016 Jun 27.

PMID:
27350374
12.

Rice bran derivatives alleviate microglia activation: possible involvement of MAPK pathway.

Bhatia HS, Baron J, Hagl S, Eckert GP, Fiebich BL.

J Neuroinflammation. 2016 Jun 14;13(1):148. doi: 10.1186/s12974-016-0615-6.

13.

Pharmacology: The Pharmacodynamics of Nutrients and Nutrient Interactions in Biological Functions.

Mohajeri MH, Eckert GP, Pauly JR, Butt CM.

Biomed Res Int. 2015;2015:974572. doi: 10.1155/2015/974572. Epub 2015 Dec 22. No abstract available.

14.

MH84: A Novel γ-Secretase Modulator/PPARγ Agonist--Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer's Disease.

Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP.

Neurochem Res. 2016 Feb;41(1-2):231-42. doi: 10.1007/s11064-015-1765-0. Epub 2015 Dec 31.

PMID:
26721513
15.

Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.

Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP.

Brain. 2015 Dec;138(Pt 12):3632-53. doi: 10.1093/brain/awv290. Epub 2015 Oct 21.

PMID:
26490331
16.

Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components.

Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP.

Molecules. 2015 Sep 11;20(9):16524-39. doi: 10.3390/molecules200916524.

17.

Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability.

Hagl S, Kocher A, Schiborr C, Kolesova N, Frank J, Eckert GP.

Neurochem Int. 2015 Oct;89:234-42. doi: 10.1016/j.neuint.2015.07.026. Epub 2015 Aug 5.

PMID:
26254982
18.

Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice.

Hagl S, Berressem D, Grewal R, Sus N, Frank J, Eckert GP.

Nutr Neurosci. 2016;19(1):1-10. doi: 10.1179/1476830515Y.0000000040. Epub 2015 Aug 4.

PMID:
26241203
19.

¹H- and ¹³C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease.

Doert A, Pilatus U, Zanella F, Müller WE, Eckert GP.

J Neural Transm (Vienna). 2015 Apr;122(4):541-50. doi: 10.1007/s00702-015-1387-3. Epub 2015 Mar 6.

PMID:
25742870
20.

Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation--impact of Ras-/Rho-prenylation.

Afshordel S, Kern B, Clasohm J, König H, Priester M, Weissenberger J, Kögel D, Eckert GP.

Pharmacol Res. 2015 Jan;91:69-77. doi: 10.1016/j.phrs.2014.11.006. Epub 2014 Dec 8.

PMID:
25497898

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