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Polysomnographic Endotyping to Select Obstructive Sleep Apnea Patients for Oral Appliances.

Bamagoos AA, Cistulli PA, Sutherland K, Madronio M, Eckert DJ, Hess L, Edwards BA, Wellman A, Sands SA.

Ann Am Thorac Soc. 2019 Aug 9. doi: 10.1513/AnnalsATS.201903-190OC. [Epub ahead of print]


Pharmacokinetics of Risankizumab in Asian Healthy Subjects and Patients With Moderate to Severe Plaque Psoriasis, Generalized Pustular Psoriasis, and Erythrodermic Psoriasis.

Khatri A, Eckert D, Oberoi R, Suleiman A, Pang Y, Cheng L, Othman AA.

J Clin Pharmacol. 2019 Jun 30. doi: 10.1002/jcph.1473. [Epub ahead of print]


PKR activation by non-canonical ligands: a 5'-triphosphate requirement versus antisense contamination.

Safran SA, Eckert DM, Leslie EA, Bass BL.

RNA. 2019 Jun 25. pii: rna.071910.119. doi: 10.1261/rna.071910.119. [Epub ahead of print]


Combination therapy with mandibular advancement and expiratory positive airway pressure valves reduces obstructive sleep apnea severity.

Lai V, Tong BK, Tran C, Ricciardiello A, Donegan M, Murray NP, Carberry JC, Eckert DJ.

Sleep. 2019 Aug 1;42(8). pii: zsz119. doi: 10.1093/sleep/zsz119.


A small viral potassium ion channel with an inherent inward rectification.

Eckert D, Schulze T, Stahl J, Rauh O, Van Etten JL, Hertel B, Schroeder I, Moroni A, Thiel G.

Channels (Austin). 2019 Dec;13(1):124-135. doi: 10.1080/19336950.2019.1605813.


The effects of zolpidem in obstructive sleep apnea - An open-label pilot study.

Carberry JC, Grunstein RR, Eckert DJ.

J Sleep Res. 2019 Apr 10:e12853. doi: 10.1111/jsr.12853. [Epub ahead of print]


Upper airway collapsibility measured using a simple wakefulness test closely relates to the pharyngeal critical closing pressure during sleep in obstructive sleep apnea.

Osman AM, Carberry JC, Burke PGR, Toson B, Grunstein RR, Eckert DJ.

Sleep. 2019 Jul 8;42(7). pii: zsz080. doi: 10.1093/sleep/zsz080.


Dose-dependent effects of mandibular advancement on upper airway collapsibility and muscle function in obstructive sleep apnea.

Bamagoos AA, Cistulli PA, Sutherland K, Ngiam J, Burke PGR, Bilston LE, Butler JE, Eckert DJ.

Sleep. 2019 Jun 11;42(6). pii: zsz049. doi: 10.1093/sleep/zsz049.


A randomised controlled trial of nasal decongestant to treat obstructive sleep apnoea in people with cervical spinal cord injury.

Wijesuriya NS, Eckert DJ, Jordan AS, Schembri R, Lewis C, Meaklim H, Booker L, Brown D, Graco M, Berlowitz DJ.

Spinal Cord. 2019 Jul;57(7):579-585. doi: 10.1038/s41393-019-0256-6. Epub 2019 Feb 13.


Familial chronic megacolon presenting in childhood or adulthood: Seeking the presumed gene association.

Camilleri M, Wieben E, Eckert D, Carlson P, Hurley O'Dwyer R, Gibbons D, Acosta A, Klee EW.

Neurogastroenterol Motil. 2019 Apr;31(4):e13550. doi: 10.1111/nmo.13550. Epub 2019 Jan 20.


Editorial: Obstructive Sleep Apnea and the Brain.

Gouveris H, Eckert DJ.

Front Surg. 2018 Dec 21;5:78. doi: 10.3389/fsurg.2018.00078. eCollection 2018. No abstract available.


Reboxetine and hyoscine butylbromide improve upper airway function during nonrapid eye movement and suppress rapid eye movement sleep in healthy individuals.

Lim R, Carberry JC, Wellman A, Grunstein R, Eckert DJ.

Sleep. 2019 Apr 1;42(4). pii: zsy261. doi: 10.1093/sleep/zsy261.


The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial.

Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, Eckert DJ, White DP, Wellman A.

Am J Respir Crit Care Med. 2019 May 15;199(10):1267-1276. doi: 10.1164/rccm.201808-1493OC.


A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.

Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch LJ, Eckert D, Hebisch M, Fischer J, Kesavan J, Weykopf B, Schneider L, Holtkamp D, Beck H, Till A, Wüllner U, Ziller MJ, Wagner W, Peitz M, Brüstle O.

Nat Commun. 2018 Oct 2;9(1):4047. doi: 10.1038/s41467-018-06398-5.


Polysomnography with an epiglottic pressure catheter does not alter obstructive sleep apnea severity or sleep efficiency.

Carter SG, Carberry JC, Grunstein RR, Eckert DJ.

J Sleep Res. 2018 Oct 1:e12773. doi: 10.1111/jsr.12773. [Epub ahead of print]


Screening for Postpartum Depression by Hospital-Based Perinatal Nurses.

Logsdon MC, Vogt K, Davis DW, Myers J, Hogan F, Eckert D, Masterson K.

MCN Am J Matern Child Nurs. 2018 Nov/Dec;43(6):324-329. doi: 10.1097/NMC.0000000000000470.


The effect of acute morphine on obstructive sleep apnoea: a randomised double-blind placebo-controlled crossover trial.

Rowsell L, Wong KKH, Yee BJ, Eckert DJ, Somogyi AA, Duffin J, Grunstein RR, Wang D.

Thorax. 2019 Feb;74(2):177-184. doi: 10.1136/thoraxjnl-2018-211675. Epub 2018 Aug 30.


New insights into the timing and potential mechanisms of respiratory-induced cortical arousals in obstructive sleep apnea.

Amatoury J, Jordan AS, Toson B, Nguyen C, Wellman A, Eckert DJ.

Sleep. 2018 Nov 1;41(11). doi: 10.1093/sleep/zsy160.


Extended-Release Morphine for Chronic Breathlessness in Pulmonary Arterial Hypertension-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.

Ferreira DH, Ekström M, Sajkov D, Vandersman Z, Eckert DJ, Currow DC.

J Pain Symptom Manage. 2018 Oct;56(4):483-492. doi: 10.1016/j.jpainsymman.2018.07.010. Epub 2018 Jul 19.


Challenges and Perspectives to the Rise in General Psychiatry Residency Applications.

Agapoff JR 4th, Tonai C, Eckert DM, Gavero G, Goebert DA.

Acad Psychiatry. 2018 Oct;42(5):674-676. doi: 10.1007/s40596-018-0923-5. Epub 2018 Jul 5. No abstract available.


Effect of 1 month of zopiclone on obstructive sleep apnoea severity and symptoms: a randomised controlled trial.

Carter SG, Carberry JC, Cho G, Fisher LP, Rollo CM, Stevens DJ, D'Rozario AL, McKenzie DK, Grunstein RR, Eckert DJ.

Eur Respir J. 2018 Jul 19;52(1). pii: 1800149. doi: 10.1183/13993003.00149-2018. Print 2018 Jul.


Inspiratory pre-motor potentials during quiet breathing in ageing and chronic obstructive pulmonary disease.

Nguyen DAT, Boswell-Ruys CL, McBain RA, Eckert DJ, Gandevia SC, Butler JE, Hudson AL.

J Physiol. 2018 Dec;596(24):6173-6189. doi: 10.1113/JP275764. Epub 2018 Jul 29.


PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo.

Parisotto M, Grelet E, El Bizri R, Dai Y, Terzic J, Eckert D, Gargowitsch L, Bornert JM, Metzger D.

J Exp Med. 2018 Jun 4;215(6):1749-1763. doi: 10.1084/jem.20171207. Epub 2018 May 9.


Effects of morphine on respiratory load detection, load magnitude perception, and tactile sensation in obstructive sleep apnea.

Tomazini Martins R, Carberry JC, Gandevia SC, Butler JE, Eckert DJ.

J Appl Physiol (1985). 2018 Aug 1;125(2):393-400. doi: 10.1152/japplphysiol.00065.2018. Epub 2018 Apr 26.


Genioglossus reflex responses to negative upper airway pressure are altered in people with tetraplegia and obstructive sleep apnoea.

Wijesuriya NS, Gainche L, Jordan AS, Berlowitz DJ, LeGuen M, Rochford PD, O'Donoghue FJ, Ruehland WR, Carberry JC, Butler JE, Eckert DJ.

J Physiol. 2018 Jul;596(14):2853-2864. doi: 10.1113/JP275222. Epub 2018 Apr 25.


Contaminant concentration versus flow velocity: drivers of biodegradation and microbial growth in groundwater model systems.

Grösbacher M, Eckert D, Cirpka OA, Griebler C.

Biodegradation. 2018 Jun;29(3):211-232. doi: 10.1007/s10532-018-9824-2. Epub 2018 Feb 28.


Pharmacokinetic and Chemical Synthesis Optimization of a Potent d-Peptide HIV Entry Inhibitor Suitable for Extended-Release Delivery.

Redman JS, Francis JN, Marquardt R, Papac D, Mueller AL, Eckert DM, Welch BD, Kay MS.

Mol Pharm. 2018 Mar 5;15(3):1169-1179. doi: 10.1021/acs.molpharmaceut.7b01004. Epub 2018 Feb 22.


Obstructive sleep apnea: current perspectives.

Osman AM, Carter SG, Carberry JC, Eckert DJ.

Nat Sci Sleep. 2018 Jan 23;10:21-34. doi: 10.2147/NSS.S124657. eCollection 2018. Review.


Sleep-Disordered Breathing in People with Multiple Sclerosis: Prevalence, Pathophysiological Mechanisms, and Disease Consequences.

Hensen HA, Krishnan AV, Eckert DJ.

Front Neurol. 2018 Jan 15;8:740. doi: 10.3389/fneur.2017.00740. eCollection 2017. Review.


Role of common hypnotics on the phenotypic causes of obstructive sleep apnoea: paradoxical effects of zolpidem.

Carberry JC, Fisher LP, Grunstein RR, Gandevia SC, McKenzie DK, Butler JE, Eckert DJ.

Eur Respir J. 2017 Dec 28;50(6). pii: 1701344. doi: 10.1183/13993003.01344-2017. Print 2017 Dec.


PGE2 EP1 receptor inhibits vasopressin-dependent water reabsorption and sodium transport in mouse collecting duct.

Nasrallah R, Zimpelmann J, Eckert D, Ghossein J, Geddes S, Beique JC, Thibodeau JF, Kennedy CRJ, Burns KD, Hébert RL.

Lab Invest. 2018 Mar;98(3):360-370. doi: 10.1038/labinvest.2017.133. Epub 2017 Dec 18.


Effects of liraglutide on weight, satiation, and gastric functions in obesity: a randomised, placebo-controlled pilot trial.

Halawi H, Khemani D, Eckert D, O'Neill J, Kadouh H, Grothe K, Clark MM, Burton DD, Vella A, Acosta A, Zinsmeister AR, Camilleri M.

Lancet Gastroenterol Hepatol. 2017 Dec;2(12):890-899. doi: 10.1016/S2468-1253(17)30285-6. Epub 2017 Sep 27.


Loquacious-PD facilitates Drosophila Dicer-2 cleavage through interactions with the helicase domain and dsRNA.

Trettin KD, Sinha NK, Eckert DM, Apple SE, Bass BL.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7939-E7948. doi: 10.1073/pnas.1707063114. Epub 2017 Sep 5.


Phenotypic approaches to positional therapy for obstructive sleep apnoea.

Eckert DJ.

Sleep Med Rev. 2018 Feb;37:175-176. doi: 10.1016/j.smrv.2017.06.007. Epub 2017 Jun 23. No abstract available.


A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.

Currow D, Watts GJ, Johnson M, McDonald CF, Miners JO, Somogyi AA, Denehy L, McCaffrey N, Eckert DJ, McCloud P, Louw S, Lam L, Greene A, Fazekas B, Clark KC, Fong K, Agar MR, Joshi R, Kilbreath S, Ferreira D, Ekström M; Australian national Palliative Care Clinical Studies Collaborative (PaCCSC).

BMJ Open. 2017 Jul 17;7(7):e018100. doi: 10.1136/bmjopen-2017-018100.


Personalized Management Approach for OSA.

Carberry JC, Amatoury J, Eckert DJ.

Chest. 2018 Mar;153(3):744-755. doi: 10.1016/j.chest.2017.06.011. Epub 2017 Jun 16. Review.


An automated and reliable method for breath detection during variable mask pressures in awake and sleeping humans.

Nguyen CD, Amatoury J, Carberry JC, Eckert DJ.

PLoS One. 2017 Jun 13;12(6):e0179030. doi: 10.1371/journal.pone.0179030. eCollection 2017.


Therapeutic CPAP Level Predicts Upper Airway Collapsibility in Patients With Obstructive Sleep Apnea.

Landry SA, Joosten SA, Eckert DJ, Jordan AS, Sands SA, White DP, Malhotra A, Wellman A, Hamilton GS, Edwards BA.

Sleep. 2017 Jun 1;40(6). doi: 10.1093/sleep/zsx056.


Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults.

Taranto-Montemurro L, Sands SA, Azarbarzin A, Marques M, de Melo CM, Edwards BA, Eckert DJ, Messineo L, White DP, Wellman A.

Ann Am Thorac Soc. 2017 Jul;14(7):1177-1183. doi: 10.1513/AnnalsATS.201701-006OC.


Is fluid overload a target to treat sleep disordered breathing in patients with end-stage renal disease, and what are the underlying mechanisms?

Arzt M, Eckert DJ.

Eur Respir J. 2017 Apr 5;49(4). pii: 1700443. doi: 10.1183/13993003.00443-2017. Print 2017 Apr. No abstract available.


Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients With Obstructive Sleep Apnea.

Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A.

Sleep. 2017 Feb 1;40(2). doi: 10.1093/sleep/zsw047.


Potential mechanisms of effects of serum-derived bovine immunoglobulin/protein isolate therapy in patients with diarrhea-predominant irritable bowel syndrome.

Valentin N, Camilleri M, Carlson P, Harrington SC, Eckert D, O'Neill J, Burton D, Chen J, Shaw AL, Acosta A.

Physiol Rep. 2017 Mar;5(5). pii: e13170. doi: 10.14814/phy2.13170.


Rectal gas volume: Defining cut-offs for screening for evacuation disorders in patients with constipation.

Park SY, Khemani D, Acosta A, Eckert D, Camilleri M.

Neurogastroenterol Motil. 2017 Jul;29(7). doi: 10.1111/nmo.13044. Epub 2017 Mar 6.


Reply: Is the Muscle the Only Potential Target of Desipramine in Obstructive Sleep Apnea Syndrome?

Taranto-Montemurro L, Sands SA, Edwards BA, Eckert DJ, White DP, Wellman A.

Am J Respir Crit Care Med. 2017 Jun 15;195(12):1678-1679. doi: 10.1164/rccm.201701-0172LE. No abstract available.


Phenotypic approaches to obstructive sleep apnoea - New pathways for targeted therapy.

Eckert DJ.

Sleep Med Rev. 2018 Feb;37:45-59. doi: 10.1016/j.smrv.2016.12.003. Epub 2016 Dec 18. Review.


Central sleep apnea in multiple sclerosis: a pilot study.

Lin M, Krishnan AV, Eckert DJ.

Sleep Breath. 2017 Sep;21(3):691-696. doi: 10.1007/s11325-016-1442-9. Epub 2016 Dec 14.


Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep.

Randerath W, Verbraecken J, Andreas S, Arzt M, Bloch KE, Brack T, Buyse B, De Backer W, Eckert DJ, Grote L, Hagmeyer L, Hedner J, Jennum P, La Rovere MT, Miltz C, McNicholas WT, Montserrat J, Naughton M, Pepin JL, Pevernagie D, Sanner B, Testelmans D, Tonia T, Vrijsen B, Wijkstra P, Levy P.

Eur Respir J. 2017 Jan 18;49(1). pii: 1600959. doi: 10.1183/13993003.00959-2016. Print 2017 Jan.


Rectal Gas Volume Measured by Computerized Tomography Identifies Evacuation Disorders in Patients With Constipation.

Park SY, Khemani D, Nelson AD, Eckert D, Camilleri M.

Clin Gastroenterol Hepatol. 2017 Apr;15(4):543-552.e4. doi: 10.1016/j.cgh.2016.11.013. Epub 2016 Nov 14.


Population pharmacokinetics of paritaprevir, ombitasvir, dasabuvir, ritonavir and ribavirin in hepatitis C virus genotype 1 infection: analysis of six phase III trials.

Mensing S, Eckert D, Sharma S, Polepally AR, Khatri A, Podsadecki TJ, Awni WM, Menon RM, Dutta S.

Br J Clin Pharmacol. 2017 Mar;83(3):527-539. doi: 10.1111/bcp.13138. Epub 2016 Nov 3.


Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation.

Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A.

Eur Respir J. 2016 Nov;48(5):1340-1350. doi: 10.1183/13993003.00823-2016. Epub 2016 Oct 6.

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