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Items: 30

1.

Safety, Pharmacokinetics, and Food Effect of Tebipenem Pivoxil Hydrobromide After Single and Multiple Ascending Oral Doses in Healthy Adult Subjects.

Eckburg PB, Jain A, Walpole S, Moore G, Utley L, Manyak E, Dane A, Melnick D.

Antimicrob Agents Chemother. 2019 Jul 1. pii: AAC.00618-19. doi: 10.1128/AAC.00618-19. [Epub ahead of print]

2.

Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, An Intravenous Potentiator, After Single and Multiple Ascending Doses and When Combined with Beta-Lactam Antibiotics in Healthy Subjects.

Eckburg PB, Lister T, Walpole S, Keutzer T, Utley L, Tomayko J, Kopp E, Farinola N, Coleman S.

Antimicrob Agents Chemother. 2019 Jul 1. pii: AAC.00892-19. doi: 10.1128/AAC.00892-19. [Epub ahead of print]

3.

Fosfomycin for injection (ZTI-01) vs Piperacillin-Tazobactam (PIP-TAZ) for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP): ZEUS, A Phase 2/3 Randomized Trial.

Kaye KS, Rice LB, Dane A, Stus V, Sagan O, Fedosiuk E, Das A, Skarinsky D, Eckburg PB, Ellis-Grosse EJ.

Clin Infect Dis. 2019 Mar 6. pii: ciz181. doi: 10.1093/cid/ciz181. [Epub ahead of print]

PMID:
30861061
4.

Omadacycline for Community-Acquired Bacterial Pneumonia.

Stets R, Popescu M, Gonong JR, Mitha I, Nseir W, Madej A, Kirsch C, Das AF, Garrity-Ryan L, Steenbergen JN, Manley A, Eckburg PB, Tzanis E, McGovern PC, Loh E.

N Engl J Med. 2019 Feb 7;380(6):517-527. doi: 10.1056/NEJMoa1800201.

PMID:
30726692
5.

Omadacycline for Acute Bacterial Skin and Skin-Structure Infections.

O'Riordan W, Green S, Overcash JS, Puljiz I, Metallidis S, Gardovskis J, Garrity-Ryan L, Das AF, Tzanis E, Eckburg PB, Manley A, Villano SA, Steenbergen JN, Loh E.

N Engl J Med. 2019 Feb 7;380(6):528-538. doi: 10.1056/NEJMoa1800170.

PMID:
30726689
6.

Macrolide therapy for community-acquired pneumonia due to atypical pathogens: outcome assessment at an early time point.

File TM Jr, Eckburg PB, Talbot GH, Llorens L, Friedland HD.

Int J Antimicrob Agents. 2017 Aug;50(2):247-251. doi: 10.1016/j.ijantimicag.2017.01.043. Epub 2017 Jun 6.

PMID:
28599867
7.

Single- and Multiple-Dose Study To Determine the Safety, Tolerability, Pharmacokinetics, and Food Effect of Oral MRX-I versus Linezolid in Healthy Adult Subjects.

Eckburg PB, Ge Y, Hafkin B.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02181-16. doi: 10.1128/AAC.02181-16. Print 2017 Apr.

8.

Efficacy of ceftaroline fosamil for bacteremia associated with community-acquired bacterial pneumonia.

Jandourek A, Smith A, Llorens L, Thye DA, Eckburg PB, Friedland HD.

Hosp Pract (1995). 2014 Feb;42(1):75-8. doi: 10.3810/hp.2014.02.1094.

PMID:
24566599
9.

Assessment of ceftaroline fosamil in the treatment of community-acquired bacterial pneumonia due to Streptococcus pneumoniae: insights from two randomized trials.

Shorr AF, Kollef M, Eckburg PB, Llorens L, Friedland HD.

Diagn Microbiol Infect Dis. 2013 Mar;75(3):298-303. doi: 10.1016/j.diagmicrobio.2012.12.002. Epub 2013 Jan 26.

PMID:
23357290
10.

CANVAS 1 and 2: analysis of clinical response at day 3 in two phase 3 trials of ceftaroline fosamil versus vancomycin plus aztreonam in treatment of acute bacterial skin and skin structure infections.

Friedland HD, O'Neal T, Biek D, Eckburg PB, Rank DR, Llorens L, Smith A, Witherell GW, Laudano JB, Thye D.

Antimicrob Agents Chemother. 2012 May;56(5):2231-6. doi: 10.1128/AAC.05738-11. Epub 2012 Feb 6.

11.

FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia.

Low DE, File TM Jr, Eckburg PB, Talbot GH, David Friedland H, Lee J, Llorens L, Critchley IA, Thye DA; FOCUS 2 investigators.

J Antimicrob Chemother. 2011 Apr;66 Suppl 3:iii33-44. doi: 10.1093/jac/dkr097.

PMID:
21482568
12.

FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia.

File TM Jr, Low DE, Eckburg PB, Talbot GH, Friedland HD, Lee J, Llorens L, Critchley IA, Thye DA; FOCUS 1 investigators.

J Antimicrob Chemother. 2011 Apr;66 Suppl 3:iii19-32. doi: 10.1093/jac/dkr096.

PMID:
21482566
13.

Review of ceftaroline fosamil microbiology: integrated FOCUS studies.

Critchley IA, Eckburg PB, Jandourek A, Biek D, Friedland HD, Thye DA.

J Antimicrob Chemother. 2011 Apr;66 Suppl 3:iii45-51. doi: 10.1093/jac/dkr098. Review.

PMID:
21482569
14.

Integrated analysis of FOCUS 1 and FOCUS 2: randomized, doubled-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia.

File TM Jr, Low DE, Eckburg PB, Talbot GH, Friedland HD, Lee J, Llorens L, Critchley I, Thye D.

Clin Infect Dis. 2010 Dec 15;51(12):1395-405. doi: 10.1086/657313. Epub 2010 Nov 10. Erratum in: Clin Infect Dis. 2011 Apr 1;52(7):967.

PMID:
21067350
15.

The role of microbes in Crohn's disease.

Eckburg PB, Relman DA.

Clin Infect Dis. 2007 Jan 15;44(2):256-62. Epub 2006 Dec 12. Review.

PMID:
17173227
16.

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult.

Chiu CY, Rouskin S, Koshy A, Urisman A, Fischer K, Yagi S, Schnurr D, Eckburg PB, Tompkins LS, Blackburn BG, Merker JD, Patterson BK, Ganem D, DeRisi JL.

Clin Infect Dis. 2006 Oct 15;43(8):e71-6. Epub 2006 Sep 1.

PMID:
16983602
17.

Assembly of the human intestinal microbiota.

Dethlefsen L, Eckburg PB, Bik EM, Relman DA.

Trends Ecol Evol. 2006 Sep;21(9):517-23. Epub 2006 Jul 3. Review.

PMID:
16820245
18.

Metagenomic analysis of the human distal gut microbiome.

Gill SR, Pop M, Deboy RT, Eckburg PB, Turnbaugh PJ, Samuel BS, Gordon JI, Relman DA, Fraser-Liggett CM, Nelson KE.

Science. 2006 Jun 2;312(5778):1355-9.

19.

Rapid quantitative profiling of complex microbial populations.

Palmer C, Bik EM, Eisen MB, Eckburg PB, Sana TR, Wolber PK, Relman DA, Brown PO.

Nucleic Acids Res. 2006 Jan 10;34(1):e5.

20.

Molecular analysis of the bacterial microbiota in the human stomach.

Bik EM, Eckburg PB, Gill SR, Nelson KE, Purdom EA, Francois F, Perez-Perez G, Blaser MJ, Relman DA.

Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):732-7. Epub 2006 Jan 4.

21.

Diversity of the human intestinal microbial flora.

Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA.

Science. 2005 Jun 10;308(5728):1635-8. Epub 2005 Apr 14.

22.

Monkeypox and medical ethics.

DiGiulio DB, Eckburg PB.

Pediatr Infect Dis J. 2004 May;23(5):482; author reply 483. No abstract available.

PMID:
15131485
23.

Monkeypox in the Western hemisphere.

DiGiulio DB, Eckburg PB.

N Engl J Med. 2004 Apr 22;350(17):1790-1; author reply 1790-1. No abstract available.

PMID:
15106264
24.

Human monkeypox.

Di Giulio DB, Eckburg PB.

Lancet Infect Dis. 2004 Apr;4(4):199. No abstract available.

PMID:
15050935
25.

Human monkeypox: an emerging zoonosis.

Di Giulio DB, Eckburg PB.

Lancet Infect Dis. 2004 Jan;4(1):15-25. Review. Erratum in: Lancet Infect Dis. 2004 Apr;4(4):251.

PMID:
14720564
26.

Archaea and their potential role in human disease.

Eckburg PB, Lepp PW, Relman DA.

Infect Immun. 2003 Feb;71(2):591-6. Review. No abstract available.

27.
28.

Brain abscess due to Listeria monocytogenes: five cases and a review of the literature.

Eckburg PB, Montoya JG, Vosti KL.

Medicine (Baltimore). 2001 Jul;80(4):223-35. Review. No abstract available.

29.

Clinical and chest radiographic findings among persons with sputum culture positive for Mycobacterium gordonae: a review of 19 cases.

Eckburg PB, Buadu EO, Stark P, Sarinas PS, Chitkara RK, Kuschner WG.

Chest. 2000 Jan;117(1):96-102.

PMID:
10631205
30.

Invasive fungal sinusitis due to Scedosporium apiospermum in a patient with AIDS.

Eckburg PB, Zolopa AR, Montoya JG.

Clin Infect Dis. 1999 Jul;29(1):212-3. No abstract available.

PMID:
10433595

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