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Items: 1 to 50 of 394

1.

On-Demand Manufacturing of Direct Compressible Tablets: Can Formulation Be Simplified?

Azad MA, Osorio JG, Wang A, Klee DM, Eccles ME, Grela E, Sloan R, Hammersmith G, Rapp K, Brancazio D, Myerson AS.

Pharm Res. 2019 Oct 24;36(12):167. doi: 10.1007/s11095-019-2716-2.

PMID:
31650274
2.

Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types.

Rodger EJ, Chatterjee A, Stockwell PA, Eccles MR.

Clin Epigenetics. 2019 Aug 5;11(1):114. doi: 10.1186/s13148-019-0710-5.

3.

Genome-wide miRNA methylome analysis in oral cancer: possible biomarkers associated with patient survival.

Roy R, Chatterjee A, Das D, Ray A, Singh R, Chattopadhyay E, Sarkar N, Eccles M, Pal M, Maitra A, Roy B.

Epigenomics. 2019 Apr;11(5):473-487. doi: 10.2217/epi-2018-0078. Epub 2019 Mar 15.

PMID:
30875235
4.

Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy.

Emran AA, Chatterjee A, Rodger EJ, Tiffen JC, Gallagher SJ, Eccles MR, Hersey P.

Trends Immunol. 2019 Apr;40(4):328-344. doi: 10.1016/j.it.2019.02.004. Epub 2019 Mar 7. Review.

5.

Genome-Scale Single Nucleotide Resolution Analysis of DNA Methylation in Human Autosomal Dominant Polycystic Kidney Disease.

Bowden SA, Rodger EJ, Bates M, Chatterjee A, Eccles MR, Stayner C.

Am J Nephrol. 2018;48(6):415-424. doi: 10.1159/000494739. Epub 2018 Nov 21.

PMID:
30463078
6.

Marked Global DNA Hypomethylation Is Associated with Constitutive PD-L1 Expression in Melanoma.

Chatterjee A, Rodger EJ, Ahn A, Stockwell PA, Parry M, Motwani J, Gallagher SJ, Shklovskaya E, Tiffen J, Eccles MR, Hersey P.

iScience. 2018 Jun 29;4:312-325. doi: 10.1016/j.isci.2018.05.021. Epub 2018 Jun 28.

7.

SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma.

Kaur G, Li CG, Chantry A, Stayner C, Horsfield J, Eccles MR.

Oncotarget. 2018 Jun 1;9(42):26852-26867. doi: 10.18632/oncotarget.25516. eCollection 2018 Jun 1.

8.

MIS416 as a siRNA Delivery System with the Ability to Target Antigen-Presenting Cells.

Mainini F, Larsen DS, Webster GA, Young SL, Eccles MR.

Nucleic Acid Ther. 2018 Aug;28(4):225-232. doi: 10.1089/nat.2017.0695. Epub 2018 Jun 12.

9.

A Guide for Designing and Analyzing RNA-Seq Data.

Chatterjee A, Ahn A, Rodger EJ, Stockwell PA, Eccles MR.

Methods Mol Biol. 2018;1783:35-80. doi: 10.1007/978-1-4939-7834-2_3.

PMID:
29767357
10.

Targeted Therapies for Autosomal Dominant Polycystic Kidney Disease.

Stayner C, Brooke DG, Bates M, Eccles MR.

Curr Med Chem. 2019;26(17):3081-3102. doi: 10.2174/0929867325666180508095654. Review.

PMID:
29737248
11.

PAX2-Related Disorder.

Bower MA, Schimmenti LA, Eccles MR.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019.
2007 Jun 8 [updated 2018 Feb 8].

12.

Celebrate through self care.

Eccles M.

Aust Nurs Midwifery J. 2017 May;24(10):16-20.

PMID:
29274266
13.

The Genes of Life and Death: A Potential Role for Placental-Specific Genes in Cancer: Active retrotransposons in the placenta encode unique functional genes that may also be used by cancer cells to promote malignancy.

Macaulay EC, Chatterjee A, Cheng X, Baguley BC, Eccles MR, Morison IM.

Bioessays. 2017 Nov;39(11). doi: 10.1002/bies.201700091. Epub 2017 Oct 4. Review.

PMID:
28976008
14.

A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNA.

Ludgate JL, Wright J, Stockwell PA, Morison IM, Eccles MR, Chatterjee A.

BMC Med Genomics. 2017 Aug 31;10(1):54. doi: 10.1186/s12920-017-0290-1.

15.

Epigenetic drivers of tumourigenesis and cancer metastasis.

Chatterjee A, Rodger EJ, Eccles MR.

Semin Cancer Biol. 2018 Aug;51:149-159. doi: 10.1016/j.semcancer.2017.08.004. Epub 2017 Aug 12. Review.

16.

The Slow Cycling Phenotype: A Growing Problem for Treatment Resistance in Melanoma.

Ahn A, Chatterjee A, Eccles MR.

Mol Cancer Ther. 2017 Jun;16(6):1002-1009. doi: 10.1158/1535-7163.MCT-16-0535. Review.

17.

Comparative assessment of DNA methylation patterns between reduced representation bisulfite sequencing and Sequenom EpiTyper methylation analysis.

Chatterjee A, Macaulay EC, Ahn A, Ludgate JL, Stockwell PA, Weeks RJ, Parry MF, Foster TJ, Knarston IM, Eccles MR, Morison IM.

Epigenomics. 2017 Jun;9(6):823-832. doi: 10.2217/epi-2016-0176. Epub 2017 May 19.

18.

An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations.

Stayner C, Poole CA, McGlashan SR, Pilanthananond M, Brauning R, Markie D, Lett B, Slobbe L, Chae A, Johnstone AC, Jensen CG, McEwan JC, Dittmer K, Parker K, Wiles A, Blackburne W, Leichter A, Leask M, Pinnapureddy A, Jennings M, Horsfield JA, Walker RJ, Eccles MR.

Sci Rep. 2017 May 9;7(1):1601. doi: 10.1038/s41598-017-01519-4.

19.

MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours.

Leichter AL, Sullivan MJ, Eccles MR, Chatterjee A.

Mol Cancer. 2017 Jan 19;16(1):15. doi: 10.1186/s12943-017-0584-0. Review.

20.

Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis.

Chatterjee A, Stockwell PA, Ahn A, Rodger EJ, Leichter AL, Eccles MR.

Oncotarget. 2017 Jan 24;8(4):6085-6101. doi: 10.18632/oncotarget.14042.

21.

Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns.

Chatterjee A, Rodger EJ, Morison IM, Eccles MR, Stockwell PA.

Methods Mol Biol. 2017;1537:249-277. Review.

PMID:
27924599
22.

"Better" clinical decisions do not necessarily require more time to make.

McCleary N, Francis JJ, Campbell MK, Ramsay CR, Eccles MP, Treweek S, Allan J.

J Clin Epidemiol. 2017 Feb;82:173-174. doi: 10.1016/j.jclinepi.2016.11.004. Epub 2016 Nov 15. No abstract available.

PMID:
27864067
23.

Repression of CMIP transcription by WT1 is relevant to podocyte health.

Moktefi A, Zhang SY, Vachin P, Ory V, Henique C, Audard V, Rucker-Martin C, Gouadon E, Eccles M, Schedl A, Heidet L, Ollero M, Sahali D, Pawlak A.

Kidney Int. 2016 Dec;90(6):1298-1311. doi: 10.1016/j.kint.2016.07.016. Epub 2016 Sep 17.

PMID:
27650733
24.

Printed educational messages fail to increase use of thiazides as first-line medication for hypertension in primary care: a cluster randomized controlled trial [ISRCTN72772651].

Zwarenstein M, Grimshaw JM, Presseau J, Francis JJ, Godin G, Johnston M, Eccles MP, Tetroe J, Shiller SK, Croxford R, Kelsall D, Paterson JM, Austin PC, Tu K, Yun L, Hux JE.

Implement Sci. 2016 Sep 17;11(1):124. doi: 10.1186/s13012-016-0486-3.

25.

scan_tcga tools for integrated epigenomic and transcriptomic analysis of tumor subgroups.

Chatterjee A, Stockwell PA, Rodger EJ, Parry MF, Eccles MR.

Epigenomics. 2016 Oct;8(10):1315-1330. Epub 2016 Sep 14.

26.

A theory-based process evaluation alongside a randomised controlled trial of printed educational messages to increase primary care physicians' prescription of thiazide diuretics for hypertension [ISRCTN72772651].

Presseau J, Grimshaw JM, Tetroe JM, Eccles MP, Francis JJ, Godin G, Graham ID, Hux JE, Johnston M, Légaré F, Lemyre L, Robinson N, Zwarenstein M.

Implement Sci. 2016 Sep 13;11(1):121. doi: 10.1186/s13012-016-0485-4.

27.

Tools developed and disseminated by guideline producers to promote the uptake of their guidelines.

Flodgren G, Hall AM, Goulding L, Eccles MP, Grimshaw JM, Leng GC, Shepperd S.

Cochrane Database Syst Rev. 2016 Aug 22;(8):CD010669. doi: 10.1002/14651858.CD010669.pub2. Review.

PMID:
27546228
28.

A primary care Web-based Intervention Modeling Experiment replicated behavior changes seen in earlier paper-based experiment.

Treweek S, Francis JJ, Bonetti D, Barnett K, Eccles MP, Hudson J, Jones C, Pitts NB, Ricketts IW, Sullivan F, Weal M, MacLennan G.

J Clin Epidemiol. 2016 Dec;80:116-122. doi: 10.1016/j.jclinepi.2016.07.008. Epub 2016 Jul 26.

PMID:
27470610
29.

NRAS and EPHB6 mutation rates differ in metastatic melanomas of patients in the North Island versus South Island of New Zealand.

Jones AM, Ferguson P, Gardner J, Rooker S, Sutton T, Ahn A, Chatterjee A, Bickley VM, Sarwar M, Emanuel P, Kenwright D, Shepherd PR, Eccles MR.

Oncotarget. 2016 Jul 5;7(27):41017-41030. doi: 10.18632/oncotarget.9351.

30.

Bridging Small Molecules to Modified Bacterial Microparticles Using a Disulphide Linkage: MIS416 as a Cargo Delivery System.

Mainini F, Larsen DS, Webster GA, Young SL, Eccles MR.

PLoS One. 2015 Dec 22;10(12):e0145403. doi: 10.1371/journal.pone.0145403. eCollection 2015.

31.

Multi-platform microRNA profiling of hepatoblastoma patients using formalin fixed paraffin embedded archival samples.

Leichter AL, Purcell RV, Sullivan MJ, Eccles MR, Chatterjee A.

Gigascience. 2015 Nov 25;4:54. doi: 10.1186/s13742-015-0099-9. eCollection 2015.

32.

Large animal models of rare genetic disorders: sheep as phenotypically relevant models of human genetic disease.

Pinnapureddy AR, Stayner C, McEwan J, Baddeley O, Forman J, Eccles MR.

Orphanet J Rare Dis. 2015 Sep 2;10:107. doi: 10.1186/s13023-015-0327-5. Review.

33.

Erratum: A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients.

Chatterjee A, Leichter AL, Fan V, Tsai P, Purcell RV, Sullivan MJ, Eccles MR.

Sci Rep. 2015 Sep 2;5:13505. doi: 10.1038/srep13505. No abstract available.

34.

Understanding effects in reviews of implementation interventions using the Theoretical Domains Framework.

Little EA, Presseau J, Eccles MP.

Implement Sci. 2015 Jun 17;10:90. doi: 10.1186/s13012-015-0280-7.

35.

A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients.

Chatterjee A, Leichter AL, Fan V, Tsai P, Purcell RV, Sullivan MJ, Eccles MR.

Sci Rep. 2015 Jun 3;5:10438. doi: 10.1038/srep10438. Erratum in: Sci Rep. 2015;5:13505.

36.

DNA methylation and epigenomics: new technologies and emerging concepts.

Chatterjee A, Eccles MR.

Genome Biol. 2015 May 21;16:103. doi: 10.1186/s13059-015-0674-5.

37.

Tailored interventions to address determinants of practice.

Baker R, Camosso-Stefinovic J, Gillies C, Shaw EJ, Cheater F, Flottorp S, Robertson N, Wensing M, Fiander M, Eccles MP, Godycki-Cwirko M, van Lieshout J, Jäger C.

Cochrane Database Syst Rev. 2015 Apr 29;(4):CD005470. doi: 10.1002/14651858.CD005470.pub3. Review.

PMID:
25923419
38.

A mixed-methods evaluation of transformational change in NHS North East.

Hunter DJ, Erskine J, Hicks C, McGovern T, Small A, Lugsden E, Whitty P, Steen IN, Eccles M.

Southampton (UK): NIHR Journals Library; 2014 Nov.

39.

The use of Latin squares and related block designs in implementation research.

Steen IN, Campbell MK, Eccles MP, Grimshaw JM, Ramsay CR, Russell IT.

J Clin Epidemiol. 2014 Dec;67(12):1299-301. doi: 10.1016/j.jclinepi.2014.07.007. Epub 2014 Oct 22. No abstract available.

PMID:
25440752
40.

G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter.

Stevens AJ, Stuffrein-Roberts S, Cree SL, Gibb A, Miller AL, Doudney K, Aitchison A, Eccles MR, Joyce PR, Filichev VV, Kennedy MA.

PLoS One. 2014 Dec 1;9(12):e113955. doi: 10.1371/journal.pone.0113955. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0122940.

41.

Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media.

Kunnen B, Macdonald C, Doronin A, Jacques S, Eccles M, Meglinski I.

J Biophotonics. 2015 Apr;8(4):317-23. doi: 10.1002/jbio.201400104. Epub 2014 Oct 18.

PMID:
25328034
42.

Are multifaceted interventions more effective than single-component interventions in changing health-care professionals' behaviours? An overview of systematic reviews.

Squires JE, Sullivan K, Eccles MP, Worswick J, Grimshaw JM.

Implement Sci. 2014 Oct 6;9:152. doi: 10.1186/s13012-014-0152-6. Review.

43.

Predicting perioperative mortality after oesophagectomy: a systematic review of performance and methods of multivariate models.

Warnell I, Chincholkar M, Eccles M.

Br J Anaesth. 2015 Jan;114(1):32-43. doi: 10.1093/bja/aeu294. Epub 2014 Sep 17. Review.

44.

Looking inside the black box: results of a theory-based process evaluation exploring the results of a randomized controlled trial of printed educational messages to increase primary care physicians' diabetic retinopathy referrals [Trial registration number ISRCTN72772651].

Grimshaw JM, Presseau J, Tetroe J, Eccles MP, Francis JJ, Godin G, Graham ID, Hux JE, Johnston M, Légaré F, Lemyre L, Robinson N, Zwarenstein M.

Implement Sci. 2014 Aug 6;9:86. doi: 10.1186/1748-5908-9-86.

45.

Tailored implementation of evidence-based practice for patients with chronic diseases.

Wensing M, Huntink E, van Lieshout J, Godycki-Cwirko M, Kowalczyk A, Jäger C, Steinhäuser J, Aakhus E, Flottorp S, Eccles M, Baker R.

PLoS One. 2014 Jul 8;9(7):e101981. doi: 10.1371/journal.pone.0101981. eCollection 2014.

46.

Improving Diabetes care through Examining, Advising, and prescribing (IDEA): protocol for a theory-based cluster randomised controlled trial of a multiple behaviour change intervention aimed at primary healthcare professionals.

Presseau J, Hawthorne G, Sniehotta FF, Steen N, Francis JJ, Johnston M, Mackintosh J, Grimshaw JM, Kaner E, Elovainio M, Deverill M, Coulthard T, Brown H, Hunter M, Eccles MP.

Implement Sci. 2014 May 24;9:61. doi: 10.1186/1748-5908-9-61.

47.

Selective decontamination of the digestive tract in critically ill patients treated in intensive care units: a mixed-methods feasibility study (the SuDDICU study).

Francis JJ, Duncan EM, Prior ME, Maclennan GS, Dombrowski S, Bellingan GU, Campbell MK, Eccles MP, Rose L, Rowan KM, Shulman R, Peter R Wilson A, Cuthbertson BH.

Health Technol Assess. 2014 Apr;18(25):1-170. doi: 10.3310/hta18250.

48.

Polycystic kidney disease - where gene dosage counts.

Eccles MR, Stayner CA.

F1000Prime Rep. 2014 Apr 1;6:24. doi: 10.12703/P6-24. eCollection 2014. Review.

49.

Reflective and automatic processes in health care professional behaviour: a dual process model tested across multiple behaviours.

Presseau J, Johnston M, Heponiemi T, Elovainio M, Francis JJ, Eccles MP, Steen N, Hrisos S, Stamp E, Grimshaw JM, Hawthorne G, Sniehotta FF.

Ann Behav Med. 2014 Dec;48(3):347-58. doi: 10.1007/s12160-014-9609-8.

PMID:
24648021
50.

Increased paired box transcription factor 8 has a survival function in glioma.

Hung N, Chen YJ, Taha A, Olivecrona M, Boet R, Wiles A, Warr T, Shaw A, Eiholzer R, Baguley BC, Eccles MR, Braithwaite AW, Macfarlane M, Royds JA, Slatter T.

BMC Cancer. 2014 Mar 6;14:159. doi: 10.1186/1471-2407-14-159.

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