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Items: 29

1.

ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα.

Gonzalez D, Luyten A, Bartholdy B, Zhou Q, Kardosova M, Ebralidze A, Swanson KD, Radomska HS, Zhang P, Kobayashi SS, Welner RS, Levantini E, Steidl U, Chong G, Collombet S, Choi MH, Friedman AD, Scott LM, Alberich-Jorda M, Tenen DG.

J Biol Chem. 2017 Nov 17;292(46):18924-18936. doi: 10.1074/jbc.M117.811109. Epub 2017 Sep 12.

2.

Acetylation of C/EBPα inhibits its granulopoietic function.

Bararia D, Kwok HS, Welner RS, Numata A, Sárosi MB, Yang H, Wee S, Tschuri S, Ray D, Weigert O, Levantini E, Ebralidze AK, Gunaratne J, Tenen DG.

Nat Commun. 2016 Mar 23;7:10968. doi: 10.1038/ncomms10968.

3.

Dissecting the role of aberrant DNA methylation in human leukaemia.

Amabile G, Di Ruscio A, Müller F, Welner RS, Yang H, Ebralidze AK, Zhang H, Levantini E, Qi L, Martinelli G, Brummelkamp T, Le Beau MM, Figueroa ME, Bock C, Tenen DG.

Nat Commun. 2015 May 22;6:7091. doi: 10.1038/ncomms8091.

4.

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.

Staber PB, Zhang P, Ye M, Welner RS, Levantini E, Di Ruscio A, Ebralidze AK, Bach C, Zhang H, Zhang J, Vanura K, Delwel R, Yang H, Huang G, Tenen DG.

Blood. 2014 Oct 9;124(15):2391-9. doi: 10.1182/blood-2014-01-550855. Epub 2014 Sep 3.

5.

Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.

Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, Nerlov C, Cammenga J, Saez B, Scadden DT, Bonifer C, Ye M, Tenen DG.

Cancer Cell. 2013 Nov 11;24(5):575-88. doi: 10.1016/j.ccr.2013.09.018. Epub 2013 Oct 31. Erratum in: Cancer Cell. 2014 Feb 10;25(2):257. Diruscio, Annalisa [corrected to Di Ruscio, Annalisa].

6.

DNMT1-interacting RNAs block gene-specific DNA methylation.

Di Ruscio A, Ebralidze AK, Benoukraf T, Amabile G, Goff LA, Terragni J, Figueroa ME, De Figueiredo Pontes LL, Alberich-Jorda M, Zhang P, Wu M, D'Alò F, Melnick A, Leone G, Ebralidze KK, Pradhan S, Rinn JL, Tenen DG.

Nature. 2013 Nov 21;503(7476):371-6. doi: 10.1038/nature12598. Epub 2013 Oct 9.

7.

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells.

Amabile G, Welner RS, Nombela-Arrieta C, D'Alise AM, Di Ruscio A, Ebralidze AK, Kraytsberg Y, Ye M, Kocher O, Neuberg DS, Khrapko K, Silberstein LE, Tenen DG.

Blood. 2013 Feb 21;121(8):1255-64. doi: 10.1182/blood-2012-06-434407. Epub 2012 Dec 4.

8.

C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.

Alberich-Jordà M, Wouters B, Balastik M, Shapiro-Koss C, Zhang H, Di Ruscio A, Radomska HS, Ebralidze AK, Amabile G, Ye M, Zhang J, Lowers I, Avellino R, Melnick A, Figueroa ME, Valk PJ, Delwel R, Tenen DG.

J Clin Invest. 2012 Dec;122(12):4490-504. doi: 10.1172/JCI65102. Epub 2012 Nov 19. Erratum in: J Clin Invest. 2013 Jan 2;123(1):526. DiRuscio, Annalisa [corrected to Di Ruscio, Annalisa].

9.

RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.

Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG.

EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285.

10.

CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells.

O'Brien KB, Alberich-Jordà M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S.

Development. 2010 Jul;137(13):2147-56. doi: 10.1242/dev.037150.

11.

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

Guibal FC, Alberich-Jorda M, Hirai H, Ebralidze A, Levantini E, Di Ruscio A, Zhang P, Santana-Lemos BA, Neuberg D, Wagers AJ, Rego EM, Tenen DG.

Blood. 2009 Dec 24;114(27):5415-25. doi: 10.1182/blood-2008-10-182071. Epub 2009 Oct 1.

12.

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.

Ebralidze AK, Guibal FC, Steidl U, Zhang P, Lee S, Bartholdy B, Jorda MA, Petkova V, Rosenbauer F, Huang G, Dayaram T, Klupp J, O'Brien KB, Will B, Hoogenkamp M, Borden KL, Bonifer C, Tenen DG.

Genes Dev. 2008 Aug 1;22(15):2085-92. doi: 10.1101/gad.1654808.

13.

The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis.

Hoogenkamp M, Krysinska H, Ingram R, Huang G, Barlow R, Clarke D, Ebralidze A, Zhang P, Tagoh H, Cockerill PN, Tenen DG, Bonifer C.

Mol Cell Biol. 2007 Nov;27(21):7425-38. Epub 2007 Sep 4.

14.

A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.

Steidl U, Steidl C, Ebralidze A, Chapuy B, Han HJ, Will B, Rosenbauer F, Becker A, Wagner K, Koschmieder S, Kobayashi S, Costa DB, Schulz T, O'Brien KB, Verhaak RG, Delwel R, Haase D, Trümper L, Krauter J, Kohwi-Shigematsu T, Griesinger F, Tenen DG.

J Clin Invest. 2007 Sep;117(9):2611-20.

15.

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.

Steidl U, Rosenbauer F, Verhaak RG, Gu X, Ebralidze A, Otu HH, Klippel S, Steidl C, Bruns I, Costa DB, Wagner K, Aivado M, Kobbe G, Valk PJ, Passegué E, Libermann TA, Delwel R, Tenen DG.

Nat Genet. 2006 Nov;38(11):1269-77. Epub 2006 Oct 15.

PMID:
17041602
16.

RNA leaching of transcription factors disrupts transcription in myotonic dystrophy.

Ebralidze A, Wang Y, Petkova V, Ebralidse K, Junghans RP.

Science. 2004 Jan 16;303(5656):383-7. Epub 2003 Dec 4.

17.
18.

Spinocerebellar mossy fiber terminal topography in the NR2C/PKC gamma double mutant cerebellum.

Ji Z, Ebralidze A, Tonegawa S, Vogel MW.

Brain Res Dev Brain Res. 1996 Nov 22;97(1):138-42.

PMID:
8946062
19.

Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.

Ebralidze AK, Rossi DJ, Tonegawa S, Slater NT.

J Neurosci. 1996 Aug 15;16(16):5014-25.

20.

Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice.

Poss KD, Thomas MJ, Ebralidze AK, O'Dell TJ, Tonegawa S.

Neuron. 1995 Oct;15(4):867-73.

21.

The mts1 gene and control of tumor metastasis.

Grigorian MS, Tulchinsky EM, Zain S, Ebralidze AK, Kramerov DA, Kriajevska MV, Georgiev GP, Lukanidin EM.

Gene. 1993 Dec 15;135(1-2):229-38. Review.

PMID:
8276262
22.

[Preparation of recombinant metastazin and characteristics of it].

Cardenas MA, Vorovich MF, Ebralidze AK, Chertov OIu, Lukanidin EM.

Bioorg Khim. 1993 Apr;19(4):420-6. Russian.

PMID:
8494565
23.

Structure of gene mts1, transcribed in metastatic mouse tumor cells.

Tulchinsky EM, Grigorian MS, Ebralidze AK, Milshina NI, Lukanidin EM.

Gene. 1990 Mar 15;87(2):219-23.

PMID:
2332170
24.

[Structure of the mts271 gene, coding a new calcium-binding protein].

Tul'chinskiĭ EM, Ebralidze AK, Grigorian MS, Mil'shchina NV, Lukanidin EM.

Genetika. 1989 Jul;25(7):1150-9. Russian.

PMID:
2806900
25.
26.

[Study of transcription of the DNA sequence of a mts271 clone in various tumor and normal mouse cells].

Grigorian MS, Ebralidze AK, Tyl'chinskiĭ EM, Revazova ES, Senin VM, Lukanidin EM.

Genetika. 1989 Jun;25(6):993-1000. Russian.

PMID:
2478418
27.

[Isolation of cDNA clones which are specifically transcribed in metastatic and nonmetastatic murine tumors].

Ebralidze AK, Tul'chinskiĭ EM, Grigorian MS, Senin VM, Lukanidin EM.

Genetika. 1989 May;25(5):932-6. Russian.

PMID:
2744442
29.

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