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Items: 6

1.

Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates.

Pieper R, Ebert-Khosla S, Cane D, Khosla C.

Biochemistry. 1996 Feb 20;35(7):2054-60.

PMID:
8652546
2.

Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits.

McDaniel R, Ebert-Khosla S, Hopwood DA, Khosla C.

Nature. 1995 Jun 15;375(6532):549-54.

PMID:
7791871
3.

Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase.

McDaniel R, Ebert-Khosla S, Fu H, Hopwood DA, Khosla C.

Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11542-6.

4.

Engineered biosynthesis of novel polyketides.

McDaniel R, Ebert-Khosla S, Hopwood DA, Khosla C.

Science. 1993 Dec 3;262(5139):1546-50.

PMID:
8248802
5.

Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins.

Khosla C, McDaniel R, Ebert-Khosla S, Torres R, Sherman DH, Bibb MJ, Hopwood DA.

J Bacteriol. 1993 Apr;175(8):2197-204.

6.

Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: role for the acyl carrier protein.

Khosla C, Ebert-Khosla S, Hopwood DA.

Mol Microbiol. 1992 Nov;6(21):3237-49.

PMID:
1453961

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