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Items: 1 to 50 of 200

1.

Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A.

Burgermeister E, Battaglin F, Eladly F, Wu W, Herweck F, Schulte N, Betge J, Härtel N, Kather JN, Weis CA, Gaiser T, Marx A, Weiss C, Hofheinz R, Miller IS, Loupakis F, Lenz HJ, Byrne AT, Ebert MP.

EBioMedicine. 2019 Jul;45:139-154. doi: 10.1016/j.ebiom.2019.07.004. Epub 2019 Jul 9.

2.

Detection of mutational patterns in cell-free DNA of colorectal cancer by custom amplicon sequencing.

Herrmann S, Zhan T, Betge J, Rauscher B, Belle S, Gutting T, Schulte N, Jesenofsky R, Härtel N, Gaiser T, Hofheinz RD, Ebert MP, Boutros M.

Mol Oncol. 2019 Aug;13(8):1669-1683. doi: 10.1002/1878-0261.12539. Epub 2019 Jul 19.

3.

MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer.

Zhan T, Ambrosi G, Wandmacher AM, Rauscher B, Betge J, Rindtorff N, Häussler RS, Hinsenkamp I, Bamberg L, Hessling B, Müller-Decker K, Erdmann G, Burgermeister E, Ebert MP, Boutros M.

Nat Commun. 2019 May 16;10(1):2197. doi: 10.1038/s41467-019-09898-0.

4.

Analysis of the Course of Chronic Pancreatitis: Pancreatic Burnout Rates Are Only Increased in a Subgroup of Patients With Alcoholic Chronic Pancreatitis.

Hirth M, Weiss C, Hardt P, Gubergrits N, Härtel N, Ebert MP, Schneider A.

Pancreas. 2019 May/Jun;48(5):726-733. doi: 10.1097/MPA.0000000000001302.

PMID:
31091222
5.

Management of immune related adverse events induced by immune checkpoint inhibition.

Teufel A, Zhan T, Härtel N, Bornschein J, Ebert MP, Schulte N.

Cancer Lett. 2019 Aug 1;456:80-87. doi: 10.1016/j.canlet.2019.04.018. Epub 2019 Apr 30.

PMID:
31051213
6.

Random gene sets in predicting survival of patients with hepatocellular carcinoma.

Itzel T, Spang R, Maass T, Munker S, Roessler S, Ebert MP, Schlitt HJ, Herr W, Evert M, Teufel A.

J Mol Med (Berl). 2019 Jun;97(6):879-888. doi: 10.1007/s00109-019-01764-2. Epub 2019 Apr 17.

PMID:
31001651
7.

Aberrant brain structural large-scale connectome in Crohn's disease.

Thomann AK, Reindl W, Wüstenberg T, Kmuche D, Ebert MP, Szabo K, Wolf RC, Hirjak D, Niesler B, Griebe M, Thomann PA.

Neurogastroenterol Motil. 2019 Jun;31(6):e13593. doi: 10.1111/nmo.13593. Epub 2019 Apr 14.

PMID:
30983094
8.

Pharmacological treatment of hepatocellular carcinoma with cavoatrial tumor thrombus - case series and literature review.

Zhan T, Sollors J, Steinebrunner N, Schlitt HJ, Stroszczynski C, Weiss KH, Ebert MP, Teufel A.

Z Gastroenterol. 2019 Apr;57(4):501-507. doi: 10.1055/a-0855-4469. Epub 2019 Apr 9.

PMID:
30965380
9.

A multicenter open-label phase II trial to evaluate nivolumab and ipilimumab for 2nd line therapy in elderly patients with advanced esophageal squamous cell cancer (RAMONA).

Meindl-Beinker NM, Betge J, Gutting T, Burgermeister E, Belle S, Zhan T, Schulte N, Maenz M, Ebert MP, Haertel N.

BMC Cancer. 2019 Mar 14;19(1):231. doi: 10.1186/s12885-019-5446-2.

10.

Clinical Course of Chronic Pancreatitis in Elderly Patients.

Hirth M, Härtel N, Weiss C, Hardt P, Gubergrits N, Ebert MP, Schneider A.

Digestion. 2019 Jan 10:1-8. doi: 10.1159/000494349. [Epub ahead of print]

PMID:
30630169
11.

Clinical evaluation of the M-ANNHEIM classification: Development of the M-ANNHEIM-Surgery-Score as a new tool to monitor patients with chronic pancreatitis.

Hirth M, Weiss C, Rückert F, Pfützer RH, Wilhelm TJ, Hetjens S, Hardt PD, Gubergrits N, Ebert MP, Schneider A.

Z Gastroenterol. 2018 Dec;56(12):1481-1490. doi: 10.1055/a-0752-0439. Epub 2018 Dec 10.

PMID:
30536253
12.

SOX9 expression decreases survival of patients with intrahepatic cholangiocarcinoma by conferring chemoresistance.

Yuan X, Li J, Coulouarn C, Lin T, Sulpice L, Bergeat D, De La Torre C, Liebe R, Gretz N, Ebert MPA, Dooley S, Weng HL.

Br J Cancer. 2018 Nov;119(11):1358-1366. doi: 10.1038/s41416-018-0338-9. Epub 2018 Nov 13.

13.

Correction to: Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours.

Nwosu ZC, Battello N, Rothley M, Piorońska W, Sitek B, Ebert MP, Hofmann U, Sleeman J, Wölfl S, Meyer C, Megger DA, Dooley S.

J Exp Clin Cancer Res. 2018 Nov 2;37(1):267. doi: 10.1186/s13046-018-0939-4.

14.

Spatial Distribution of Endogenous Tissue Protease Activity in Gastric Carcinoma Mapped by MALDI Mass Spectrometry Imaging.

Erich K, Reinle K, Müller T, Munteanu B, Sammour DA, Hinsenkamp I, Gutting T, Burgermeister E, Findeisen P, Ebert MP, Krijgsveld J, Hopf C.

Mol Cell Proteomics. 2019 Jan;18(1):151-161. doi: 10.1074/mcp.RA118.000980. Epub 2018 Oct 7.

PMID:
30293968
15.

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy.

Smeets D, Miller IS, O'Connor DP, Das S, Moran B, Boeckx B, Gaiser T, Betge J, Barat A, Klinger R, van Grieken NCT, Cremolini C, Prenen H, Mazzone M, Depreeuw J, Bacon O, Fender B, Brady J, Hennessy BT, McNamara DA, Kay E, Verheul HM, Maarten N, Gallagher WM, Murphy V, Prehn JHM, Koopman M, Punt CJA, Loupakis F, Ebert MPA, Ylstra B, Lambrechts D, Byrne AT.

Nat Commun. 2018 Oct 5;9(1):4112. doi: 10.1038/s41467-018-06567-6.

16.

Impact of direct acting antiviral (DAA) treatment on glucose metabolism and reduction of pre-diabetes in patients with chronic hepatitis C.

Weidner P, Boettche D, Zimmerer T, Burgermeister E, Teufel A, Ebert MPA, Antoni C.

J Gastrointestin Liver Dis. 2018 Sep;27(3):281-289. doi: 10.15403/jgld.2014.1121.273.daa.

17.

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours.

Nwosu ZC, Battello N, Rothley M, Piorońska W, Sitek B, Ebert MP, Hofmann U, Sleeman J, Wölfl S, Meyer C, Megger DA, Dooley S.

J Exp Clin Cancer Res. 2018 Sep 3;37(1):211. doi: 10.1186/s13046-018-0872-6. Erratum in: J Exp Clin Cancer Res. 2018 Nov 2;37(1):267.

18.

A multicenter phase 4 geriatric assessment directed trial to evaluate gemcitabine +/- nab-paclitaxel in elderly pancreatic cancer patients (GrantPax).

Betge J, Chi-Kern J, Schulte N, Belle S, Gutting T, Burgermeister E, Jesenofsky R, Maenz M, Wedding U, Ebert MP, Haertel N.

BMC Cancer. 2018 Jul 18;18(1):747. doi: 10.1186/s12885-018-4665-2.

19.

Confounding influence of tamoxifen in mouse models of Cre recombinase-induced gene activity or modulation.

Hammad S, Othman A, Meyer C, Telfah A, Lambert J, Dewidar B, Werle J, Nwosu ZC, Mahli A, Dormann C, Gao Y, Gould K, Han M, Yuan X, Gogiashvili M, Hergenröder R, Hellerbrand C, Thomas M, Ebert MP, Amasheh S, Hengstler JG, Dooley S.

Arch Toxicol. 2018 Aug;92(8):2549-2561. doi: 10.1007/s00204-018-2254-4. Epub 2018 Jul 4.

PMID:
29974145
20.

Galunisertib modifies the liver fibrotic composition in the Abcb4Ko mouse model.

Hammad S, Cavalcanti E, Werle J, Caruso ML, Dropmann A, Ignazzi A, Ebert MP, Dooley S, Giannelli G.

Arch Toxicol. 2018 Jul;92(7):2297-2309. doi: 10.1007/s00204-018-2231-y. Epub 2018 May 28.

PMID:
29808285
21.

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

van Dijk E, Biesma HD, Cordes M, Smeets D, Neerincx M, Das S, Eijk PP, Murphy V, Barat A, Bacon O, Prehn JHM, Betge J, Gaiser T, Fender B, Meijer GA, McNamara DA, Klinger R, Koopman M, Ebert MPA, Kay EW, Hennessey BT, Verheul HMW, Gallagher WM, O'Connor DP, Punt CJA, Loupakis F, Lambrechts D, Byrne AT, van Grieken NCT, Ylstra B.

J Clin Oncol. 2018 Jul 10;36(20):2052-2060. doi: 10.1200/JCO.2017.77.1782. Epub 2018 May 24.

PMID:
29792754
22.

Prevalence of inflammatory bowel disease in alcoholic, non-alcoholic and autoimmune pancreatitis.

Schneider A, Hirth M, Weiss C, Weidner P, Antoni C, Thomann A, Reindl W, Ebert MP, Pfützer RH.

Z Gastroenterol. 2018 May;56(5):469-478. doi: 10.1055/s-0043-123881. Epub 2018 May 7.

PMID:
29734447
23.

PPARγ-activation increases intestinal M1 macrophages and mitigates formation of serrated adenomas in mutant KRAS mice.

Gutting T, Weber CA, Weidner P, Herweck F, Henn S, Friedrich T, Yin S, Kzhyshkowska J, Gaiser T, Janssen KP, Reindl W, Ebert MPA, Burgermeister E.

Oncoimmunology. 2018 Feb 1;7(5):e1423168. doi: 10.1080/2162402X.2017.1423168. eCollection 2018.

24.

Checkpoints and beyond - Immunotherapy in colorectal cancer.

Gutting T, Burgermeister E, Härtel N, Ebert MP.

Semin Cancer Biol. 2019 Apr;55:78-89. doi: 10.1016/j.semcancer.2018.04.003. Epub 2018 Apr 30. Review.

PMID:
29716829
25.

CRISPR/Cas9 for cancer research and therapy.

Zhan T, Rindtorff N, Betge J, Ebert MP, Boutros M.

Semin Cancer Biol. 2019 Apr;55:106-119. doi: 10.1016/j.semcancer.2018.04.001. Epub 2018 Apr 16. Review.

26.

Invitation letters increase participation in colorectal cancer screening - results from an observational study.

Zhan T, Hielscher T, Bilge A, Giese T, Schäfer C, Riemann JF, Ebert MP, Belle S.

Z Gastroenterol. 2017 Dec;55(12):1307-1312. doi: 10.1055/s-0043-121347. Epub 2017 Dec 6.

PMID:
29212101
27.

Monitoring and predicting disease activity in autoimmune pancreatitis with the M-ANNHEIM-AiP-Activity-Score.

Hirth M, Vujasinovic M, Münch M, Weiss C, Löhr M, Ebert MP, Schneider A.

Pancreatology. 2018 Jan;18(1):29-38. doi: 10.1016/j.pan.2017.10.005. Epub 2017 Oct 25.

PMID:
29158146
28.

Epigenetic silencing of tumor suppressor candidate 3 confers adverse prognosis in early colorectal cancer.

Burgermeister E, Höde P, Betge J, Gutting T, Merkel A, Wu W, Tänzer M, Mossner M, Nowak D, Magdeburg J, Rückert F, Sticht C, Breitkopf-Heinlein K, Schulte N, Härtel N, Belle S, Post S, Gaiser T, Heppner BI, Behrens HM, Röcken C, Ebert MPA.

Oncotarget. 2017 Sep 15;8(49):84714-84728. doi: 10.18632/oncotarget.20950. eCollection 2017 Oct 17.

29.

Di (2-Ethylhexyl) Phthalate and Its Role in Developing Cholestasis: An In Vitro Study on Different Liver Cell Types.

Gaitantzi H, Hakenberg P, Theobald J, Heinlein H, Cai C, Loff S, Wölfl S, Ebert MP, Breitkopf-Heinlein K, Subotic U.

J Pediatr Gastroenterol Nutr. 2018 Feb;66(2):e28-e35. doi: 10.1097/MPG.0000000000001813.

PMID:
29095348
30.

Gemcitabine combined with the monoclonal antibody nimotuzumab is an active first-line regimen in KRAS wildtype patients with locally advanced or metastatic pancreatic cancer: a multicenter, randomized phase IIb study.

Schultheis B, Reuter D, Ebert MP, Siveke J, Kerkhoff A, Berdel WE, Hofheinz R, Behringer DM, Schmidt WE, Goker E, De Dosso S, Kneba M, Yalcin S, Overkamp F, Schlegel F, Dommach M, Rohrberg R, Steinmetz T, Bulitta M, Strumberg D.

Ann Oncol. 2017 Oct 1;28(10):2429-2435. doi: 10.1093/annonc/mdx343.

PMID:
28961832
31.

Prevalence and Incidence of Autoimmune Pancreatitis in the Population Living in the Southwest of Germany.

Schneider A, Michaely H, Weiss C, Hirth M, Rückert F, Wilhelm TJ, Schönberg S, Marx A, Singer MV, Löhr JM, Ebert MP, Pfützer RH.

Digestion. 2017 Nov;96(4):187-198. doi: 10.1159/000479316. Epub 2017 Sep 29.

PMID:
28957814
32.

Intrinsic neural network dysfunction in quiescent Crohn's Disease.

Thomann AK, Griebe M, Thomann PA, Hirjak D, Ebert MP, Szabo K, Reindl W, Wolf RC.

Sci Rep. 2017 Sep 14;7(1):11579. doi: 10.1038/s41598-017-11792-y.

33.

Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma.

Nwosu ZC, Megger DA, Hammad S, Sitek B, Roessler S, Ebert MP, Meyer C, Dooley S.

Cell Mol Gastroenterol Hepatol. 2017 May 31;4(2):303-323.e1. doi: 10.1016/j.jcmgh.2017.05.004. eCollection 2017 Sep.

34.

Genetic Variants in the Manganese Superoxide Dismutase 2 Gene and in the Catalase Gene are not Associated With Alcoholic Chronic Pancreatitis.

Schneider A, Rosendahl J, Bugert P, Weiss C, Unterschütz H, Kylanpää-Bäck ML, Lempinen M, Kemppainen E, Diaconu BL, Ebert MP, Pfützer RH.

Alcohol Alcohol. 2017 Sep 1;52(5):535-541. doi: 10.1093/alcalc/agx039.

PMID:
28655148
35.

Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer.

Zuurbier L, Rahman A, Cordes M, Scheick J, Wong TJ, Rustenburg F, Joseph JC, Dynoodt P, Casey R, Drillenburg P, Gerhards M, Barat A, Klinger R, Fender B, O'Connor DP, Betge J, Ebert MP, Gaiser T, Prehn JHM, Griffioen AW, van Grieken NCT, Ylstra B, Byrne AT, van der Flier LG, Gallagher WM, Postel R.

Oncotarget. 2017 Jun 27;8(26):42949-42961. doi: 10.18632/oncotarget.17306.

36.

Diagnosing autoimmune pancreatitis with the Unifying-Autoimmune-Pancreatitis-Criteria.

Schneider A, Michaely H, Rückert F, Weiss C, Ströbel P, Belle S, Hirth M, Wilhelm TJ, Haas SL, Jesenofsky R, Schönberg S, Marx A, Singer MV, Ebert MP, Pfützer RH, Löhr JM.

Pancreatology. 2017 May - Jun;17(3):381-394. doi: 10.1016/j.pan.2017.03.005. Epub 2017 Mar 18.

PMID:
28365128
37.

BMP-9 interferes with liver regeneration and promotes liver fibrosis.

Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P.

Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23.

PMID:
28336518
38.

Risk of Cancer in Patients with Autoimmune Pancreatitis: A Single-Center Experience from Germany.

Schneider A, Hirth M, Münch M, Weiss C, Löhr JM, Ebert MP, Pfützer RH.

Digestion. 2017;95(2):172-180. doi: 10.1159/000455963. Epub 2017 Feb 23.

PMID:
28226313
39.

Lymph node retrieval in colorectal cancer: determining factors and prognostic significance.

Betge J, Harbaum L, Pollheimer MJ, Lindtner RA, Kornprat P, Ebert MP, Langner C.

Int J Colorectal Dis. 2017 Jul;32(7):991-998. doi: 10.1007/s00384-017-2778-8. Epub 2017 Feb 16.

40.

Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice.

Feng T, Dzieran J, Yuan X, Dropmann A, Maass T, Teufel A, Marhenke S, Gaiser T, Rückert F, Kleiter I, Kanzler S, Ebert MP, Vogel A, Ten Dijke P, Dooley S, Meindl-Beinker NM.

Oncogenesis. 2017 Jan 30;6(1):e294. doi: 10.1038/oncsis.2016.85.

41.

Multiple behavioral factors are associated with occurrence of large, flat colorectal polyps.

Zhan T, Hahn F, Hielscher T, Bilge A, Grüger J, Weers J, Betge J, Gaiser T, Kähler G, Ebert MP, Belle S.

Int J Colorectal Dis. 2017 Apr;32(4):575-582. doi: 10.1007/s00384-016-2717-0. Epub 2016 Nov 28.

PMID:
27896421
42.

Caveolin-1 in the regulation of cell metabolism: a cancer perspective.

Nwosu ZC, Ebert MP, Dooley S, Meyer C.

Mol Cancer. 2016 Nov 16;15(1):71. Review.

43.

Outcome of Colorectal Cancer Patients Treated with Combination Bevacizumab Therapy: A Pooled Retrospective Analysis of Three European Cohorts from the Angiopredict Initiative.

Betge J, Barat A, Murphy V, Hielscher T, Van Grieken NC, Belle S, Zhan T, Härtel N, Kripp M, Bacon O, Cordes M, Kay EW, Verheul HM, Neerincx M, Hennessy B, Hofheinz RD, Gaiser T, Ylstra B, Prehn JH, Lambrechts D, Byrne AT, Ebert MP, Schulte N.

Digestion. 2016;94(3):129-137. doi: 10.1159/000449412. Epub 2016 Oct 19.

PMID:
27756074
44.

Altered Markers of Brain Development in Crohn's Disease with Extraintestinal Manifestations - A Pilot Study.

Thomann AK, Thomann PA, Wolf RC, Hirjak D, Schmahl C, Ebert MP, Szabo K, Reindl W, Griebe M.

PLoS One. 2016 Sep 21;11(9):e0163202. doi: 10.1371/journal.pone.0163202. eCollection 2016.

45.

Inhibition of Rho-Associated Kinase 1/2 Attenuates Tumor Growth in Murine Gastric Cancer.

Hinsenkamp I, Schulz S, Roscher M, Suhr AM, Meyer B, Munteanu B, Fuchser J, Schoenberg SO, Ebert MP, Wängler B, Hopf C, Burgermeister E.

Neoplasia. 2016 Aug;18(8):500-11. doi: 10.1016/j.neo.2016.07.002.

46.

Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer.

Friedrich T, Söhn M, Gutting T, Janssen KP, Behrens HM, Röcken C, Ebert MPA, Burgermeister E.

EBioMedicine. 2016 Jun;8:159-172. doi: 10.1016/j.ebiom.2016.05.003. Epub 2016 May 5.

47.

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.

Weidner P, Söhn M, Gutting T, Friedrich T, Gaiser T, Magdeburg J, Kienle P, Ruh H, Hopf C, Behrens HM, Röcken C, Hanoch T, Seger R, Ebert MP, Burgermeister E.

Oncotarget. 2016 Aug 2;7(31):50490-50506. doi: 10.18632/oncotarget.10466.

48.

MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.

Betge J, Schneider NI, Harbaum L, Pollheimer MJ, Lindtner RA, Kornprat P, Ebert MP, Langner C.

Virchows Arch. 2016 Sep;469(3):255-65. doi: 10.1007/s00428-016-1970-5.

49.

Risk Factors for Local Recurrence of Large, Flat Colorectal Polyps after Endoscopic Mucosal Resection.

Zhan T, Hielscher T, Hahn F, Hauf C, Betge J, Ebert MP, Belle S.

Digestion. 2016;93(4):311-7. doi: 10.1159/000446364. Epub 2016 Jun 7.

PMID:
27271329
50.

Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression.

Shen Z, Liu Y, Dewidar B, Hu J, Park O, Feng T, Xu C, Yu C, Li Q, Meyer C, Ilkavets I, Müller A, Stump-Guthier C, Munker S, Liebe R, Zimmer V, Lammert F, Mertens PR, Li H, Ten Dijke P, Augustin HG, Li J, Gao B, Ebert MP, Dooley S, Li Y, Weng HL.

Am J Pathol. 2016 Jul;186(7):1874-1889. doi: 10.1016/j.ajpath.2016.03.010. Epub 2016 May 10.

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