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Items: 1 to 50 of 474

1.

Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation.

Jan M, Leventhal MJ, Morgan EA, Wengrod JC, Nag A, Drinan SD, Wollison BM, Ducar MD, Thorner AR, Leppanen S, Baronas J, Stevens J, Lane WJ, Kekre N, Ho VT, Koreth J, Cutler CS, Nikiforow S, Alyea EP 3rd, Antin JH, Soiffer RJ, Ritz J, Lindsley RC, Ebert BL.

Blood Adv. 2019 Jul 23;3(14):2199-2204. doi: 10.1182/bloodadvances.2019000445.

2.

Profiling Cell Wall Monosaccharides and Nucleotide-Sugars from Plants.

Rautengarten C, Heazlewood JL, Ebert B.

Curr Protoc Plant Biol. 2019 Jun;4(2):e20092. doi: 10.1002/cppb.20092. Epub 2019 Jun 12.

PMID:
31187943
3.

Conserved Glu-47 and Lys-50 residues are critical for UDP-N-acetylglucosamine/UMP antiport activity of the mouse Golgi-associated transporter Slc35a3.

Toscanini MA, Favarolo MB, Gonzalez Flecha FL, Ebert B, Rautengarten C, Bredeston LM.

J Biol Chem. 2019 Jun 28;294(26):10042-10054. doi: 10.1074/jbc.RA119.008827. Epub 2019 May 22.

PMID:
31118275
4.

Elevated temperatures do not trigger a conserved metabolic network response among thermotolerant yeasts.

Lehnen M, Ebert BE, Blank LM.

BMC Microbiol. 2019 May 17;19(1):100. doi: 10.1186/s12866-019-1453-3.

5.

CHIP, CCUS, and Other Acronyms: Definition, Implications, and Impact on Practice.

DeZern AE, Malcovati L, Ebert BL.

Am Soc Clin Oncol Educ Book. 2019 Jan;39:400-410. doi: 10.1200/EDBK_239083. Epub 2019 May 17.

PMID:
31099654
6.

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.

Nandakumar SK, McFarland SK, Mateyka LM, Lareau CA, Ulirsch JC, Ludwig LS, Agarwal G, Engreitz JM, Przychodzen B, McConkey M, Cowley GS, Doench JG, Maciejewski JP, Ebert BL, Root DE, Sankaran VG.

Elife. 2019 May 9;8. pii: e44080. doi: 10.7554/eLife.44080.

7.

Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs.

Sperling AS, Burgess M, Keshishian H, Gasser JA, Bhatt S, Jan M, Słabicki M, Sellar RS, Fink EC, Miller PG, Liddicoat BJ, Sievers QL, Sharma R, Adams DN, Olesinski EA, Fulciniti M, Udeshi ND, Kuhn E, Letai A, Munshi NC, Carr SA, Ebert BL.

Blood. 2019 Jul 11;134(2):160-170. doi: 10.1182/blood.2019000789. Epub 2019 May 1.

PMID:
31043423
8.

Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background.

Yin M, Chung YJ, Lindsley RC, Walker RL, Zhu YJ, Ebert BL, Meltzer PS, Aplan PD.

Blood. 2019 Jun 13;133(24):2610-2614. doi: 10.1182/blood.2018864173. Epub 2019 Apr 16.

PMID:
30992267
9.

The Transcriptome and Flux Profiling of Crabtree-Negative Hydroxy Acid-Producing Strains of Saccharomyces cerevisiae Reveals Changes in the Central Carbon Metabolism.

Jessop-Fabre MM, Dahlin J, Biron MB, Stovicek V, Ebert BE, Blank LM, Budin I, Keasling JD, Borodina I.

Biotechnol J. 2019 Apr 10:e1900013. doi: 10.1002/biot.201900013. [Epub ahead of print]

PMID:
30969019
10.

Intergenerational epigenetic inheritance of cancer susceptibility in mammals.

Lesch BJ, Tothova Z, Morgan EA, Liao Z, Bronson RT, Ebert BL, Page DC.

Elife. 2019 Apr 9;8. pii: e39380. doi: 10.7554/eLife.39380.

11.

Genomic subtyping and therapeutic targeting of acute erythroleukemia.

Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM, Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, Payne-Turner D, Tomizawa D, Kiyokawa N, Valentine M, Valentine V, Basso G, Locatelli F, Enemark EJ, Kham SKY, Yeoh AEJ, Ma X, Zhou X, Sioson E, Rusch M, Ries RE, Stieglitz E, Hunger SP, Wei AH, To LB, Lewis ID, D'Andrea RJ, Kile BT, Brown AL, Scott HS, Hahn CN, Marlton P, Pei D, Cheng C, Loh ML, Ebert BL, Meshinchi S, Haferlach T, Mullighan CG.

Nat Genet. 2019 Apr;51(4):694-704. doi: 10.1038/s41588-019-0375-1. Epub 2019 Mar 29.

PMID:
30926971
12.

Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation.

Abdulhay NJ, Fiorini C, Verboon JM, Ludwig LS, Ulirsch JC, Zieger B, Lareau CA, Mi X, Roy A, Obeng EA, Erlacher M, Gupta N, Gabriel SB, Ebert BL, Niemeyer CM, Khoriaty RN, Ancliff P, Gazda HT, Wlodarski MW, Sankaran VG.

J Exp Med. 2019 May 6;216(5):1050-1060. doi: 10.1084/jem.20181625. Epub 2019 Mar 26.

PMID:
30914438
13.

Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription.

Struntz NB, Chen A, Deutzmann A, Wilson RM, Stefan E, Evans HL, Ramirez MA, Liang T, Caballero F, Wildschut MHE, Neel DV, Freeman DB, Pop MS, McConkey M, Muller S, Curtin BH, Tseng H, Frombach KR, Butty VL, Levine SS, Feau C, Elmiligy S, Hong JA, Lewis TA, Vetere A, Clemons PA, Malstrom SE, Ebert BL, Lin CY, Felsher DW, Koehler AN.

Cell Chem Biol. 2019 May 16;26(5):711-723.e14. doi: 10.1016/j.chembiol.2019.02.009. Epub 2019 Mar 14.

PMID:
30880155
14.

Mitochondrial Dysfunction in Astrocytes Impairs the Generation of Reactive Astrocytes and Enhances Neuronal Cell Death in the Cortex Upon Photothrombotic Lesion.

Fiebig C, Keiner S, Ebert B, Schäffner I, Jagasia R, Lie DC, Beckervordersandforth R.

Front Mol Neurosci. 2019 Feb 22;12:40. doi: 10.3389/fnmol.2019.00040. eCollection 2019.

15.

A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion.

Yin S, Gambe RG, Sun J, Martinez AZ, Cartun ZJ, Regis FFD, Wan Y, Fan J, Brooks AN, Herman SEM, Ten Hacken E, Taylor-Weiner A, Rassenti LZ, Ghia EM, Kipps TJ, Obeng EA, Cibulskis CL, Neuberg D, Campagna DR, Fleming MD, Ebert BL, Wiestner A, Leshchiner I, DeCaprio JA, Getz G, Reed R, Carrasco RD, Wu CJ, Wang L.

Cancer Cell. 2019 Feb 11;35(2):283-296.e5. doi: 10.1016/j.ccell.2018.12.013. Epub 2019 Jan 31.

16.

Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome.

Ribezzo F, Snoeren IAM, Ziegler S, Stoelben J, Olofsen PA, Henic A, Ferreira MV, Chen S, Stalmann USA, Buesche G, Hoogenboezem RM, Kramann R, Platzbecker U, Raaijmakers MHGP, Ebert BL, Schneider RK.

Leukemia. 2019 Jul;33(7):1759-1772. doi: 10.1038/s41375-018-0350-3. Epub 2019 Jan 16.

PMID:
30651631
17.

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.

Haase D, Stevenson KE, Neuberg D, Maciejewski JP, Nazha A, Sekeres MA, Ebert BL, Garcia-Manero G, Haferlach C, Haferlach T, Kern W, Ogawa S, Nagata Y, Yoshida K, Graubert TA, Walter MJ, List AF, Komrokji RS, Padron E, Sallman D, Papaemmanuil E, Campbell PJ, Savona MR, Seegmiller A, Adès L, Fenaux P, Shih LY, Bowen D, Groves MJ, Tauro S, Fontenay M, Kosmider O, Bar-Natan M, Steensma D, Stone R, Heuser M, Thol F, Cazzola M, Malcovati L, Karsan A, Ganster C, Hellström-Lindberg E, Boultwood J, Pellagatti A, Santini V, Quek L, Vyas P, Tüchler H, Greenberg PL, Bejar R; International Working Group for MDS Molecular Prognostic Committee.

Leukemia. 2019 Jul;33(7):1747-1758. doi: 10.1038/s41375-018-0351-2. Epub 2019 Jan 11.

18.

Clonal Hematopoiesis of Indeterminate Potential.

Boettcher S, Ebert BL.

J Clin Oncol. 2019 Feb 10;37(5):419-422. doi: 10.1200/JCO.2018.79.3588. Epub 2018 Dec 27. No abstract available.

PMID:
30589599
19.

Jak-ing Up the Plaque's Lipid Core…and Even More.

Libby P, Molinaro R, Sellar RS, Ebert BL.

Circ Res. 2018 Nov 9;123(11):1180-1182. doi: 10.1161/CIRCRESAHA.118.314074. No abstract available.

PMID:
30571474
20.

CHIPping Away at the Pathogenesis of Heart Failure.

Libby P, Jaiswal S, Lin AE, Ebert BL.

JAMA Cardiol. 2018 Dec 19. doi: 10.1001/jamacardio.2018.4039. [Epub ahead of print] No abstract available.

PMID:
30566187
21.

Isolation and Characterization of Amniotic Fluid-Derived Extracellular Vesicles for Biomarker Discovery.

Ebert B, Rai AJ.

Methods Mol Biol. 2019;1885:287-294. doi: 10.1007/978-1-4939-8889-1_19.

PMID:
30506205
22.

Inhibition of Casein Kinase 1 Alpha in Acute Myeloid Leukemia.

Ebert BL, Krönke J.

N Engl J Med. 2018 Nov 8;379(19):1873-1874. doi: 10.1056/NEJMcibr1811318. No abstract available.

PMID:
30403945
23.

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.

Sievers QL, Petzold G, Bunker RD, Renneville A, Słabicki M, Liddicoat BJ, Abdulrahman W, Mikkelsen T, Ebert BL, Thomä NH.

Science. 2018 Nov 2;362(6414). pii: eaat0572. doi: 10.1126/science.aat0572.

24.

CHIP (Clonal Hematopoiesis of Indeterminate Potential).

Libby P, Ebert BL.

Circulation. 2018 Aug 14;138(7):666-668. doi: 10.1161/CIRCULATIONAHA.118.034392. No abstract available.

PMID:
30359133
25.

Generations of physician-scientists.

Ebert BL.

J Clin Invest. 2018 Oct 1;128(10):4208-4212. doi: 10.1172/JCI124786. Epub 2018 Oct 1. No abstract available.

26.

A Freely Mobile Subcutaneous Nodule of the Dorsal Hand.

Schoenfeld J, Ebert B, Benedetto A, Benedetto P.

Dermatol Surg. 2019 Jul;45(7):991-993. doi: 10.1097/DSS.0000000000001675. No abstract available.

PMID:
30234653
27.

A Golgi UDP-GlcNAc transporter delivers substrates for N-linked glycans and sphingolipids.

Ebert B, Rautengarten C, McFarlane HE, Rupasinghe T, Zeng W, Ford K, Scheller HV, Bacic A, Roessner U, Persson S, Heazlewood JL.

Nat Plants. 2018 Oct;4(10):792-801. doi: 10.1038/s41477-018-0235-5. Epub 2018 Sep 17.

PMID:
30224661
28.

CO2 to succinic acid - Estimating the potential of biocatalytic routes.

Liebal UW, Blank LM, Ebert BE.

Metab Eng Commun. 2018 Jun 28;7:e00075. doi: 10.1016/j.mec.2018.e00075. eCollection 2018 Dec.

29.

The Three Members of the Arabidopsis Glycosyltransferase Family 92 are Functional β-1,4-Galactan Synthases.

Ebert B, Birdseye D, Liwanag AJM, Laursen T, Rennie EA, Guo X, Catena M, Rautengarten C, Stonebloom SH, Gluza P, Pidatala VR, Andersen MCF, Cheetamun R, Mortimer JC, Heazlewood JL, Bacic A, Clausen MH, Willats WGT, Scheller HV.

Plant Cell Physiol. 2018 Dec 1;59(12):2624-2636. doi: 10.1093/pcp/pcy180.

PMID:
30184190
30.

Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations.

Lee SC, North K, Kim E, Jang E, Obeng E, Lu SX, Liu B, Inoue D, Yoshimi A, Ki M, Yeo M, Zhang XJ, Kim MK, Cho H, Chung YR, Taylor J, Durham BH, Kim YJ, Pastore A, Monette S, Palacino J, Seiler M, Buonamici S, Smith PG, Ebert BL, Bradley RK, Abdel-Wahab O.

Cancer Cell. 2018 Aug 13;34(2):225-241.e8. doi: 10.1016/j.ccell.2018.07.003.

PMID:
30107174
31.

Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.

Schneider RK, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, Van Strien PMH, Bindels EM, Heckl D, Büsche G, Fleck D, Müller-Newen G, Wongboonsin J, Ventura Ferreira M, Puelles VG, Saez-Rodriguez J, Ebert BL, Humphreys BD, Kramann R.

Cell Stem Cell. 2018 Aug 2;23(2):308-309. doi: 10.1016/j.stem.2018.07.006. No abstract available.

PMID:
30075132
32.

Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome.

Donovan KA, An J, Nowak RP, Yuan JC, Fink EC, Berry BC, Ebert BL, Fischer ES.

Elife. 2018 Aug 1;7. pii: e38430. doi: 10.7554/eLife.38430.

33.

Crbn I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice.

Fink EC, McConkey M, Adams DN, Haldar SD, Kennedy JA, Guirguis AA, Udeshi ND, Mani DR, Chen M, Liddicoat B, Svinkina T, Nguyen AT, Carr SA, Ebert BL.

Blood. 2018 Oct 4;132(14):1535-1544. doi: 10.1182/blood-2018-05-852798. Epub 2018 Jul 31.

34.

Physiologic and metabolic characterization of Saccharomyces cerevisiae reveals limitations in the synthesis of the triterpene squalene.

Ebert BE, Czarnotta E, Blank LM.

FEMS Yeast Res. 2018 Dec 1;18(8). doi: 10.1093/femsyr/foy077.

PMID:
30053028
35.

Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity.

Sievers QL, Gasser JA, Cowley GS, Fischer ES, Ebert BL.

Blood. 2018 Sep 20;132(12):1293-1303. doi: 10.1182/blood-2018-01-821769. Epub 2018 Jul 24.

36.

Discovery and Evaluation of Biosynthetic Pathways for the Production of Five Methyl Ethyl Ketone Precursors.

Tokic M, Hadadi N, Ataman M, Neves D, Ebert BE, Blank LM, Miskovic L, Hatzimanikatis V.

ACS Synth Biol. 2018 Aug 17;7(8):1858-1873. doi: 10.1021/acssynbio.8b00049. Epub 2018 Aug 7.

PMID:
30021444
37.

Predicting progression to AML.

Sellar RS, Jaiswal S, Ebert BL.

Nat Med. 2018 Jul;24(7):904-906. doi: 10.1038/s41591-018-0114-7. No abstract available.

PMID:
29988142
38.

PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.

Kahn JD, Miller PG, Silver AJ, Sellar RS, Bhatt S, Gibson C, McConkey M, Adams D, Mar B, Mertins P, Fereshetian S, Krug K, Zhu H, Letai A, Carr SA, Doench J, Jaiswal S, Ebert BL.

Blood. 2018 Sep 13;132(11):1095-1105. doi: 10.1182/blood-2018-05-850339. Epub 2018 Jun 28.

39.

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.

Bellutti F, Tigan AS, Nebenfuehr S, Dolezal M, Zojer M, Grausenburger R, Hartenberger S, Kollmann S, Doma E, Prchal-Murphy M, Uras IZ, Höllein A, Neuberg DS, Ebert BL, Ringler A, Mueller AC, Loizou JI, Hinds PW, Vogl C, Heller G, Kubicek S, Zuber J, Malumbres M, Farlik M, Villunger A, Kollmann K, Sexl V.

Cancer Discov. 2018 Jul;8(7):884-897. doi: 10.1158/2159-8290.CD-17-0912. Epub 2018 Jun 13.

40.

Carbonyl reductases from Daphnia are regulated by redox cycling compounds.

Ebert B, Ebert D, Koebsch K, Maser E, Kisiela M.

FEBS J. 2018 Aug;285(15):2869-2887. doi: 10.1111/febs.14578. Epub 2018 Jun 20.

PMID:
29893480
41.

Clonal Hematopoiesis Confers Predisposition to Both Cardiovascular Disease and Cancer: A Newly Recognized Link Between Two Major Killers.

Ebert BL, Libby P.

Ann Intern Med. 2018 Jul 17;169(2):116-117. doi: 10.7326/M18-0737. Epub 2018 May 29. No abstract available.

PMID:
29809241
42.

Genetic Optimization Algorithm for Metabolic Engineering Revisited.

Alter TB, Blank LM, Ebert BE.

Metabolites. 2018 May 16;8(2). pii: E33. doi: 10.3390/metabo8020033.

43.

Congenital and iatrogenic laryngeal and vocal abnormalities in patients with 22q11.2 deletion.

Ebert B, Sidman J, Morrell N, Roby BB.

Int J Pediatr Otorhinolaryngol. 2018 Jun;109:17-20. doi: 10.1016/j.ijporl.2018.03.006. Epub 2018 Mar 13.

PMID:
29728175
44.

Upper airway obstruction in neonates: Does sleep exacerbate symptoms?

Van Heest T, Ebert B, Roby BB, Sidman J.

Laryngoscope Investig Otolaryngol. 2018 Feb 10;3(2):78-81. doi: 10.1002/lio2.137. eCollection 2018 Apr.

45.

Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms.

Wolach O, Sellar RS, Martinod K, Cherpokova D, McConkey M, Chappell RJ, Silver AJ, Adams D, Castellano CA, Schneider RK, Padera RF, DeAngelo DJ, Wadleigh M, Steensma DP, Galinsky I, Stone RM, Genovese G, McCarroll SA, Iliadou B, Hultman C, Neuberg D, Mullally A, Wagner DD, Ebert BL.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaan8292. doi: 10.1126/scitranslmed.aan8292.

46.

Clonal Hematopoiesis after Induction Chemotherapy for Acute Myeloid Leukemia.

Steensma DP, Ebert BL.

N Engl J Med. 2018 Mar 29;378(13):1244-1245. doi: 10.1056/NEJMe1802610. No abstract available.

PMID:
29590545
47.

A decade of progress in myelodysplastic syndrome with chromosome 5q deletion.

List A, Ebert BL, Fenaux P.

Leukemia. 2018 Jul;32(7):1493-1499. doi: 10.1038/s41375-018-0029-9. Epub 2018 Jan 30. Review.

PMID:
29445113
48.

Association of mutations with morphological dysplasia in de novo acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities.

Weinberg OK, Gibson CJ, Blonquist TM, Neuberg D, Pozdnyakova O, Kuo F, Ebert BL, Hasserjian RP.

Haematologica. 2018 Apr;103(4):626-633. doi: 10.3324/haematol.2017.181842. Epub 2018 Jan 11.

49.

Gene stacking of multiple traits for high yield of fermentable sugars in plant biomass.

Aznar A, Chalvin C, Shih PM, Maimann M, Ebert B, Birdseye DS, Loqué D, Scheller HV.

Biotechnol Biofuels. 2018 Jan 9;11:2. doi: 10.1186/s13068-017-1007-6. eCollection 2018.

50.

Three UDP-xylose transporters participate in xylan biosynthesis by conveying cytosolic UDP-xylose into the Golgi lumen in Arabidopsis.

Zhao X, Liu N, Shang N, Zeng W, Ebert B, Rautengarten C, Zeng QY, Li H, Chen X, Beahan C, Bacic A, Heazlewood JL, Wu AM.

J Exp Bot. 2018 Feb 23;69(5):1125-1134. doi: 10.1093/jxb/erx448.

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