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Items: 1 to 50 of 61

1.

Multicenter Study Using Desorption-Electrospray-Ionization-Mass-Spectrometry Imaging for Breast-Cancer Diagnosis.

Porcari AM, Zhang J, Garza KY, Rodrigues-Peres RM, Lin JQ, Young JH, Tibshirani R, Nagi C, Paiva GR, Carter SA, Sarian LO, Eberlin MN, Eberlin LS.

Anal Chem. 2018 Sep 18. doi: 10.1021/acs.analchem.8b01961. [Epub ahead of print]

PMID:
30170496
2.

Desorption Electrospray Ionization Coupled with Ultraviolet Photodissociation for Characterization of Phospholipid Isomers in Tissue Sections.

Klein DR, Feider CL, Garza KY, Lin JQ, Eberlin LS, Brodbelt JS.

Anal Chem. 2018 Sep 4;90(17):10100-10104. doi: 10.1021/acs.analchem.8b03026. Epub 2018 Aug 13.

PMID:
30080398
3.

Desorption Electrospray Ionization Mass Spectrometry Imaging of Proteins Directly from Biological Tissue Sections.

Garza KY, Feider CL, Klein DR, Rosenberg JA, Brodbelt JS, Eberlin LS.

Anal Chem. 2018 Jul 3;90(13):7785-7789. doi: 10.1021/acs.analchem.8b00967. Epub 2018 Jun 15.

PMID:
29800516
4.

Analytical Technologies to Improve Human Health.

Eberlin LS.

Anal Chem. 2018 Apr 3;90(7):4235. doi: 10.1021/acs.analchem.8b01232. No abstract available.

PMID:
29609467
5.

Advances in mass spectrometry imaging coupled to ion mobility spectrometry for enhanced imaging of biological tissues.

Sans M, Feider CL, Eberlin LS.

Curr Opin Chem Biol. 2018 Feb;42:138-146. doi: 10.1016/j.cbpa.2017.12.005. Epub 2017 Dec 21. Review.

PMID:
29275246
6.

Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system.

Zhang J, Rector J, Lin JQ, Young JH, Sans M, Katta N, Giese N, Yu W, Nagi C, Suliburk J, Liu J, Bensussan A, DeHoog RJ, Garza KY, Ludolph B, Sorace AG, Syed A, Zahedivash A, Milner TE, Eberlin LS.

Sci Transl Med. 2017 Sep 6;9(406). pii: eaan3968. doi: 10.1126/scitranslmed.aan3968.

7.

Metabolic Markers and Statistical Prediction of Serous Ovarian Cancer Aggressiveness by Ambient Ionization Mass Spectrometry Imaging.

Sans M, Gharpure K, Tibshirani R, Zhang J, Liang L, Liu J, Young JH, Dood RL, Sood AK, Eberlin LS.

Cancer Res. 2017 Jun 1;77(11):2903-2913. doi: 10.1158/0008-5472.CAN-16-3044. Epub 2017 Apr 17.

8.

Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma.

Gouw AM, Eberlin LS, Margulis K, Sullivan DK, Toal GG, Tong L, Zare RN, Felsher DW.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4300-4305. doi: 10.1073/pnas.1617709114. Epub 2017 Apr 11.

9.

Detection of Metastatic Breast and Thyroid Cancer in Lymph Nodes by Desorption Electrospray Ionization Mass Spectrometry Imaging.

Zhang J, Feider CL, Nagi C, Yu W, Carter SA, Suliburk J, Cao HST, Eberlin LS.

J Am Soc Mass Spectrom. 2017 Jun;28(6):1166-1174. doi: 10.1007/s13361-016-1570-2. Epub 2017 Feb 28.

10.

Cardiolipins Are Biomarkers of Mitochondria-Rich Thyroid Oncocytic Tumors.

Zhang J, Yu W, Ryu SW, Lin J, Buentello G, Tibshirani R, Suliburk J, Eberlin LS.

Cancer Res. 2016 Nov 15;76(22):6588-6597. doi: 10.1158/0008-5472.CAN-16-1545. Epub 2016 Sep 22.

11.

Ambient Ionization and FAIMS Mass Spectrometry for Enhanced Imaging of Multiply Charged Molecular Ions in Biological Tissues.

Feider CL, Elizondo N, Eberlin LS.

Anal Chem. 2016 Dec 6;88(23):11533-11541. Epub 2016 Nov 9.

12.

Pancreatic Cancer Surgical Resection Margins: Molecular Assessment by Mass Spectrometry Imaging.

Eberlin LS, Margulis K, Planell-Mendez I, Zare RN, Tibshirani R, Longacre TA, Jalali M, Norton JA, Poultsides GA.

PLoS Med. 2016 Aug 30;13(8):e1002108. doi: 10.1371/journal.pmed.1002108. eCollection 2016 Aug.

13.

Will Ambient Ionization Mass Spectrometry Become an Integral Technology in the Operating Room of the Future?

Zhang J, Yu W, Suliburk J, Eberlin LS.

Clin Chem. 2016 Sep;62(9):1172-4. doi: 10.1373/clinchem.2016.258723. Epub 2016 Jul 18. No abstract available.

14.

Probabilistic Segmentation of Mass Spectrometry (MS) Images Helps Select Important Ions and Characterize Confidence in the Resulting Segments.

Bemis KD, Harry A, Eberlin LS, Ferreira CR, van de Ven SM, Mallick P, Stolowitz M, Vitek O.

Mol Cell Proteomics. 2016 May;15(5):1761-72. doi: 10.1074/mcp.O115.053918. Epub 2016 Jan 21.

15.

Forensic Chemistry and Ambient Mass Spectrometry: A Perfect Couple Destined for a Happy Marriage?

Correa DN, Santos JM, Eberlin LS, Eberlin MN, Teunissen SF.

Anal Chem. 2016 Mar 1;88(5):2515-26. doi: 10.1021/acs.analchem.5b02397. Epub 2016 Feb 2.

PMID:
26768158
16.

Protein Analysis by Ambient Ionization Mass Spectrometry Using Trypsin-Immobilized Organosiloxane Polymer Surfaces.

Dulay MT, Eberlin LS, Zare RN.

Anal Chem. 2015 Dec 15;87(24):12324-30. doi: 10.1021/acs.analchem.5b03669. Epub 2015 Nov 24.

PMID:
26567450
17.

Ambient Ionization Mass Spectrometry for Cancer Diagnosis and Surgical Margin Evaluation.

Ifa DR, Eberlin LS.

Clin Chem. 2016 Jan;62(1):111-23. doi: 10.1373/clinchem.2014.237172. Epub 2015 Nov 10. Review.

18.

MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.

Shroff EH, Eberlin LS, Dang VM, Gouw AM, Gabay M, Adam SJ, Bellovin DI, Tran PT, Philbrick WM, Garcia-Ocana A, Casey SC, Li Y, Dang CV, Zare RN, Felsher DW.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6539-44. doi: 10.1073/pnas.1507228112. Epub 2015 May 11.

19.

Cardinal: an R package for statistical analysis of mass spectrometry-based imaging experiments.

Bemis KD, Harry A, Eberlin LS, Ferreira C, van de Ven SM, Mallick P, Stolowitz M, Vitek O.

Bioinformatics. 2015 Jul 15;31(14):2418-20. doi: 10.1093/bioinformatics/btv146. Epub 2015 Mar 15.

20.

The role of Abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans.

Zheng M, Zhang H, Dill DL, Clark JD, Tu S, Yablonovitch AL, Tan MH, Zhang R, Rujescu D, Wu M, Tessarollo L, Vieira W, Gottesman MM, Deng S, Eberlin LS, Zare RN, Billard JM, Gillet JP, Li JB, Peltz G.

PLoS Med. 2015 Feb 3;12(2):e1001782. doi: 10.1371/journal.pmed.1001782. eCollection 2015 Feb.

21.

DESI-MS imaging of lipids and metabolites from biological samples.

Eberlin LS.

Methods Mol Biol. 2014;1198:299-311. doi: 10.1007/978-1-4939-1258-2_20.

PMID:
25270938
22.

Imaging of whole zebra fish (Danio rerio) by desorption electrospray ionization mass spectrometry.

Chramow A, Hamid TS, Eberlin LS, Girod M, Ifa DR.

Rapid Commun Mass Spectrom. 2014 Oct 15;28(19):2084-8. doi: 10.1002/rcm.6993.

PMID:
25156598
23.

Alteration of the lipid profile in lymphomas induced by MYC overexpression.

Eberlin LS, Gabay M, Fan AC, Gouw AM, Tibshirani RJ, Felsher DW, Zare RN.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10450-5. doi: 10.1073/pnas.1409778111. Epub 2014 Jul 3.

24.

Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery.

Santagata S, Eberlin LS, Norton I, Calligaris D, Feldman DR, Ide JL, Liu X, Wiley JS, Vestal ML, Ramkissoon SH, Orringer DA, Gill KK, Dunn IF, Dias-Santagata D, Ligon KL, Jolesz FA, Golby AJ, Cooks RG, Agar NY.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11121-6. doi: 10.1073/pnas.1404724111. Epub 2014 Jun 30.

25.

Visualizing dermal permeation of sodium channel modulators by mass spectrometric imaging.

Eberlin LS, Mulcahy JV, Tzabazis A, Zhang J, Liu H, Logan MM, Roberts HJ, Lee GK, Yeomans DC, Du Bois J, Zare RN.

J Am Chem Soc. 2014 Apr 30;136(17):6401-5. doi: 10.1021/ja501635u. Epub 2014 Apr 17.

26.

A statistical modeling approach for tumor-type identification in surgical neuropathology using tissue mass spectrometry imaging.

Gholami B, Norton I, Eberlin LS, Agar NY.

IEEE J Biomed Health Inform. 2013 May;17(3):734-44.

PMID:
24592474
27.

Molecular assessment of surgical-resection margins of gastric cancer by mass-spectrometric imaging.

Eberlin LS, Tibshirani RJ, Zhang J, Longacre TA, Berry GJ, Bingham DB, Norton JA, Zare RN, Poultsides GA.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2436-41. doi: 10.1073/pnas.1400274111. Epub 2014 Feb 3.

28.

Mass spectrometry imaging as a tool for surgical decision-making.

Calligaris D, Norton I, Feldman DR, Ide JL, Dunn IF, Eberlin LS, Cooks RG, Jolesz FA, Golby AJ, Santagata S, Agar NY.

J Mass Spectrom. 2013 Nov;48(11):1178-87. doi: 10.1002/jms.3295.

29.

Desorption electrospray ionization mass spectrometry reveals lipid metabolism of individual oocytes and embryos.

González-Serrano AF, Pirro V, Ferreira CR, Oliveri P, Eberlin LS, Heinzmann J, Lucas-Hahn A, Niemann H, Cooks RG.

PLoS One. 2013 Sep 20;8(9):e74981. doi: 10.1371/journal.pone.0074981. eCollection 2013.

30.

"Dba-free" palladium intermediates of the Heck-Matsuda reaction.

Machado AH, Milagre HM, Eberlin LS, Sabino AA, Correia CR, Eberlin MN.

Org Biomol Chem. 2013 May 28;11(20):3277-81. doi: 10.1039/c3ob40142a.

PMID:
23511838
31.

Chemical aspects of the extractive methods of ambient ionization mass spectrometry.

Badu-Tawiah AK, Eberlin LS, Ouyang Z, Cooks RG.

Annu Rev Phys Chem. 2013;64:481-505. doi: 10.1146/annurev-physchem-040412-110026. Epub 2013 Jan 16. Review.

PMID:
23331308
32.

Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors.

Eberlin LS, Norton I, Orringer D, Dunn IF, Liu X, Ide JL, Jarmusch AK, Ligon KL, Jolesz FA, Golby AJ, Santagata S, Agar NY, Cooks RG.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1611-6. doi: 10.1073/pnas.1215687110. Epub 2013 Jan 8.

33.

Developmental phases of individual mouse preimplantation embryos characterized by lipid signatures using desorption electrospray ionization mass spectrometry.

Ferreira CR, Pirro V, Eberlin LS, Hallett JE, Cooks RG.

Anal Bioanal Chem. 2012 Dec;404(10):2915-26. doi: 10.1007/s00216-012-6426-4. Epub 2012 Oct 4.

34.

Mass spectrometry imaging under ambient conditions.

Wu C, Dill AL, Eberlin LS, Cooks RG, Ifa DR.

Mass Spectrom Rev. 2013 May-Jun;32(3):218-43. doi: 10.1002/mas.21360. Epub 2012 Sep 20. Review.

35.

Improved spatial resolution in the imaging of biological tissue using desorption electrospray ionization.

Campbell DI, Ferreira CR, Eberlin LS, Cooks RG.

Anal Bioanal Chem. 2012 Aug;404(2):389-98. doi: 10.1007/s00216-012-6173-6. Epub 2012 Jun 16.

PMID:
22706326
36.

Interactive hyperspectral approach for exploring and interpreting DESI-MS images of cancerous and normal tissue sections.

Pirro V, Eberlin LS, Oliveri P, Cooks RG.

Analyst. 2012 May 21;137(10):2374-80. doi: 10.1039/c2an35122f. Epub 2012 Apr 11.

37.

Data processing for 3D mass spectrometry imaging.

Xiong X, Xu W, Eberlin LS, Wiseman JM, Fang X, Jiang Y, Huang Z, Zhang Y, Cooks RG, Ouyang Z.

J Am Soc Mass Spectrom. 2012 Jun;23(6):1147-56. doi: 10.1007/s13361-012-0361-7. Epub 2012 Mar 3.

PMID:
22392622
38.

Single oocyte and single embryo lipid analysis by desorption electrospray ionization mass spectrometry.

Ferreira CR, Eberlin LS, Hallett JE, Cooks RG.

J Mass Spectrom. 2012 Jan;47(1):29-33. doi: 10.1002/jms.2022. No abstract available.

PMID:
22282086
39.

Classifying human brain tumors by lipid imaging with mass spectrometry.

Eberlin LS, Norton I, Dill AL, Golby AJ, Ligon KL, Santagata S, Cooks RG, Agar NY.

Cancer Res. 2012 Feb 1;72(3):645-54. doi: 10.1158/0008-5472.CAN-11-2465. Epub 2011 Dec 2.

40.

Desorption electrospray ionization then MALDI mass spectrometry imaging of lipid and protein distributions in single tissue sections.

Eberlin LS, Liu X, Ferreira CR, Santagata S, Agar NY, Cooks RG.

Anal Chem. 2011 Nov 15;83(22):8366-71. doi: 10.1021/ac202016x. Epub 2011 Oct 18.

41.

Distinctive glycerophospholipid profiles of human seminoma and adjacent normal tissues by desorption electrospray ionization imaging mass spectrometry.

Masterson TA, Dill AL, Eberlin LS, Mattarozzi M, Cheng L, Beck SD, Bianchi F, Cooks RG.

J Am Soc Mass Spectrom. 2011 Aug;22(8):1326-33. doi: 10.1007/s13361-011-0134-8. Epub 2011 Apr 26.

PMID:
21953186
42.

Nondestructive, histologically compatible tissue imaging by desorption electrospray ionization mass spectrometry.

Eberlin LS, Ferreira CR, Dill AL, Ifa DR, Cheng L, Cooks RG.

Chembiochem. 2011 Sep 19;12(14):2129-32. doi: 10.1002/cbic.201100411. Epub 2011 Jul 26. No abstract available.

43.

Data quality in tissue analysis using desorption electrospray ionization.

Dill AL, Eberlin LS, Costa AB, Ifa DR, Cooks RG.

Anal Bioanal Chem. 2011 Oct;401(6):1949-61. doi: 10.1007/s00216-011-5249-z. Epub 2011 Jul 26.

PMID:
21789488
44.

Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging.

Eberlin LS, Ferreira CR, Dill AL, Ifa DR, Cooks RG.

Biochim Biophys Acta. 2011 Nov;1811(11):946-60. doi: 10.1016/j.bbalip.2011.05.006. Epub 2011 May 27. Review.

45.

New ionization methods and miniature mass spectrometers for biomedicine: DESI imaging for cancer diagnostics and paper spray ionization for therapeutic drug monitoring.

Cooks RG, Manicke NE, Dill AL, Ifa DR, Eberlin LS, Costa AB, Wang H, Huang G, Ouyang Z.

Faraday Discuss. 2011;149:247-67; discussion 333-56.

PMID:
21413184
46.

Multivariate statistical identification of human bladder carcinomas using ambient ionization imaging mass spectrometry.

Dill AL, Eberlin LS, Costa AB, Zheng C, Ifa DR, Cheng L, Masterson TA, Koch MO, Vitek O, Cooks RG.

Chemistry. 2011 Mar 1;17(10):2897-902. doi: 10.1002/chem.201001692. Epub 2011 Jan 31.

47.

Perspectives in imaging using mass spectrometry.

Dill AL, Eberlin LS, Ifa DR, Cooks RG.

Chem Commun (Camb). 2011 Mar 14;47(10):2741-6. doi: 10.1039/c0cc03518a. Epub 2010 Dec 16. Review.

PMID:
21161110
48.

Multivariate statistical differentiation of renal cell carcinomas based on lipidomic analysis by ambient ionization imaging mass spectrometry.

Dill AL, Eberlin LS, Zheng C, Costa AB, Ifa DR, Cheng L, Masterson TA, Koch MO, Vitek O, Cooks RG.

Anal Bioanal Chem. 2010 Dec;398(7-8):2969-78. doi: 10.1007/s00216-010-4259-6. Epub 2010 Oct 15.

PMID:
20953777
49.

Discrimination of human astrocytoma subtypes by lipid analysis using desorption electrospray ionization imaging mass spectrometry.

Eberlin LS, Dill AL, Golby AJ, Ligon KL, Wiseman JM, Cooks RG, Agar NY.

Angew Chem Int Ed Engl. 2010 Aug 9;49(34):5953-6. doi: 10.1002/anie.201001452. No abstract available.

50.

Instantaneous chemical profiles of banknotes by ambient mass spectrometry.

Eberlin LS, Haddad R, Sarabia Neto RC, Cosso RG, Maia DR, Maldaner AO, Zacca JJ, Sanvido GB, Romão W, Vaz BG, Ifa DR, Dill A, Cooks RG, Eberlin MN.

Analyst. 2010 Oct;135(10):2533-9. doi: 10.1039/c0an00243g. Epub 2010 Jun 30.

PMID:
20593076

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