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Items: 1 to 50 of 173

1.

Acetaminophen-induced liver injury is mediated by the ion channel TRPV4.

Echtermeyer F, Eberhardt M, Risser L, Herzog C, Gueler F, Khalil M, Engel M, Vondran F, Leffler A.

FASEB J. 2019 Jun 17:fj201802233R. doi: 10.1096/fj.201802233R. [Epub ahead of print]

PMID:
31207191
2.

Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis.

Hannemann N, Cao S, Eriksson D, Schnelzer A, Jordan J, Eberhardt M, Schleicher U, Rech J, Ramming A, Uebe S, Ekici A, Cañete JD, Chen X, Bäuerle T, Vera J, Bogdan C, Schett G, Bozec A.

J Clin Invest. 2019 Apr 16;130:2669-2684. doi: 10.1172/JCI96832.

3.

SEIS: Insight's Seismic Experiment for Internal Structure of Mars.

Lognonné P, Banerdt WB, Giardini D, Pike WT, Christensen U, Laudet P, de Raucourt S, Zweifel P, Calcutt S, Bierwirth M, Hurst KJ, Ijpelaan F, Umland JW, Llorca-Cejudo R, Larson SA, Garcia RF, Kedar S, Knapmeyer-Endrun B, Mimoun D, Mocquet A, Panning MP, Weber RC, Sylvestre-Baron A, Pont G, Verdier N, Kerjean L, Facto LJ, Gharakanian V, Feldman JE, Hoffman TL, Klein DB, Klein K, Onufer NP, Paredes-Garcia J, Petkov MP, Willis JR, Smrekar SE, Drilleau M, Gabsi T, Nebut T, Robert O, Tillier S, Moreau C, Parise M, Aveni G, Ben Charef S, Bennour Y, Camus T, Dandonneau PA, Desfoux C, Lecomte B, Pot O, Revuz P, Mance D, tenPierick J, Bowles NE, Charalambous C, Delahunty AK, Hurley J, Irshad R, Liu H, Mukherjee AG, Standley IM, Stott AE, Temple J, Warren T, Eberhardt M, Kramer A, Kühne W, Miettinen EP, Monecke M, Aicardi C, André M, Baroukh J, Borrien A, Bouisset A, Boutte P, Brethomé K, Brysbaert C, Carlier T, Deleuze M, Desmarres JM, Dilhan D, Doucet C, Faye D, Faye-Refalo N, Gonzalez R, Imbert C, Larigauderie C, Locatelli E, Luno L, Meyer JR, Mialhe F, Mouret JM, Nonon M, Pahn Y, Paillet A, Pasquier P, Perez G, Perez R, Perrin L, Pouilloux B, Rosak A, Savin de Larclause I, Sicre J, Sodki M, Toulemont N, Vella B, Yana C, Alibay F, Avalos OM, Balzer MA, Bhandari P, Blanco E, Bone BD, Bousman JC, Bruneau P, Calef FJ, Calvet RJ, D'Agostino SA, de Los Santos G, Deen RG, Denise RW, Ervin J, Ferraro NW, Gengl HE, Grinblat F, Hernandez D, Hetzel M, Johnson ME, Khachikyan L, Lin JY, Madzunkov SM, Marshall SL, Mikellides IG, Miller EA, Raff W, Singer JE, Sunday CM, Villalvazo JF, Wallace MC, Banfield D, Rodriguez-Manfredi JA, Russell CT, Trebi-Ollennu A, Maki JN, Beucler E, Böse M, Bonjour C, Berenguer JL, Ceylan S, Clinton J, Conejero V, Daubar I, Dehant V, Delage P, Euchner F, Estève I, Fayon L, Ferraioli L, Johnson CL, Gagnepain-Beyneix J, Golombek M, Khan A, Kawamura T, Kenda B, Labrot P, Murdoch N, Pardo C, Perrin C, Pou L, Sauron A, Savoie D, Stähler S, Stutzmann E, Teanby NA, Tromp J, van Driel M, Wieczorek M, Widmer-Schnidrig R, Wookey J.

Space Sci Rev. 2019;215(1):12. doi: 10.1007/s11214-018-0574-6. Epub 2019 Jan 28. Review.

4.

Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a.

Lee JH, Dindorf J, Eberhardt M, Lai X, Ostalecki C, Koliha N, Gross S, Blume K, Bruns H, Wild S, Schuler G, Vera J, Baur AS.

Life Sci Alliance. 2019 Mar 7;2(2). pii: e201800205. doi: 10.26508/lsa.201800205. Print 2019 Apr.

5.

A gene regulatory architecture that controls region-independent dynamics of oligodendrocyte differentiation.

Cantone M, Küspert M, Reiprich S, Lai X, Eberhardt M, Göttle P, Beyer F, Azim K, Küry P, Wegner M, Vera J.

Glia. 2019 May;67(5):825-843. doi: 10.1002/glia.23569. Epub 2019 Feb 7.

PMID:
30730593
6.

Photocrosslinked Dextran-Based Hydrogels as Carrier System for the Cells and Cytokines Induce Bone Regeneration in Critical Size Defects in Mice.

Ritz U, Eberhardt M, Klein A, Frank P, Götz H, Hofmann A, Rommens PM, Jonas U.

Gels. 2018 Jul 20;4(3). pii: E63. doi: 10.3390/gels4030063.

7.

Prevention of canine ocular thelaziosis (Thelazia callipaeda) with a combination of milbemycin oxime and afoxolaner (Nexgard Spectra®) in endemic areas in France and Spain.

Lebon W, Guillot J, Álvarez MJ, Antonio Bazaga J, Cortes-Dubly ML, Dumont P, Eberhardt M, Gómez H, Pennant O, Siméon N, Beugnet F, Halos L.

Parasite. 2019;26:1. doi: 10.1051/parasite/2019001. Epub 2019 Jan 15.

8.

Etomidate and propylene glycol activate nociceptive TRP ion channels.

Niedermirtl F, Eberhardt M, Namer B, Leffler A, Nau C, Reeh PW, Kistner K.

Mol Pain. 2018 Jan-Dec;14:1744806918811699. doi: 10.1177/1744806918811699. Epub 2018 Oct 22.

PMID:
30345869
9.

Prevalence of Total, Diagnosed, and Undiagnosed Diabetes Among Adults: United States, 2013-2016.

Mendola ND, Chen TC, Gu Q, Eberhardt MS, Saydah S.

NCHS Data Brief. 2018 Sep;(319):1-8.

10.

Anemia Prevalence and Trends in Adults Aged 65 and Older: U.S. National Health and Nutrition Examination Survey: 2001-2004 to 2013-2016.

Seitz AE, Eberhardt MS, Lukacs SL.

J Am Geriatr Soc. 2018 Dec;66(12):2431-2432. doi: 10.1111/jgs.15530. Epub 2018 Sep 24. No abstract available.

PMID:
30247771
11.

Suspected Exposure to Filoviruses Among People Contacting Wildlife in Southwestern Uganda.

Smiley Evans T, Tutaryebwa L, Gilardi KV, Barry PA, Marzi A, Eberhardt M, Ssebide B, Cranfield MR, Mugisha O, Mugisha E, Kellermann S, Mazet JAK, Johnson CK.

J Infect Dis. 2018 Nov 22;218(suppl_5):S277-S286. doi: 10.1093/infdis/jiy251.

12.

Bacterial Adherence and Dwelling Probability: Two Drivers of Early Alveolar Infection by Streptococcus pneumoniae Identified in Multi-Level Mathematical Modeling.

Santos G, Lai X, Eberhardt M, Vera J.

Front Cell Infect Microbiol. 2018 May 15;8:159. doi: 10.3389/fcimb.2018.00159. eCollection 2018.

13.

A web platform for the network analysis of high-throughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy.

Dreyer FS, Cantone M, Eberhardt M, Jaitly T, Walter L, Wittmann J, Gupta SK, Khan FM, Wolkenhauer O, Pützer BM, Jäck HM, Heinzerling L, Vera J.

Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt B):2315-2328. doi: 10.1016/j.bbadis.2018.01.020. Epub 2018 Feb 23.

14.

A single-cysteine mutant and chimeras of essential Leishmania Erv can complement the loss of Erv1 but not of Mia40 in yeast.

Specht S, Liedgens L, Duarte M, Stiegler A, Wirth U, Eberhardt M, Tomás A, Hell K, Deponte M.

Redox Biol. 2018 May;15:363-374. doi: 10.1016/j.redox.2017.12.010. Epub 2017 Dec 23.

15.

Activation of the capsaicin-receptor TRPV1 by the acetaminophen metabolite N-arachidonoylaminophenol results in cytotoxicity.

Stueber T, Meyer S, Jangra A, Hage A, Eberhardt M, Leffler A.

Life Sci. 2018 Feb 1;194:67-74. doi: 10.1016/j.lfs.2017.12.024. Epub 2017 Dec 19.

PMID:
29273526
16.

TRPA1 and TRPV1 are required for lidocaine-evoked calcium influx and neuropeptide release but not cytotoxicity in mouse sensory neurons.

Eberhardt M, Stueber T, de la Roche J, Herzog C, Leffler A, Reeh PW, Kistner K.

PLoS One. 2017 Nov 15;12(11):e0188008. doi: 10.1371/journal.pone.0188008. eCollection 2017.

17.

Differential cytotoxicity and intracellular calcium-signalling following activation of the calcium-permeable ion channels TRPV1 and TRPA1.

Stueber T, Eberhardt MJ, Caspi Y, Lev S, Binshtok A, Leffler A.

Cell Calcium. 2017 Dec;68:34-44. doi: 10.1016/j.ceca.2017.10.003. Epub 2017 Oct 18.

PMID:
29129206
18.

Blepharitis.

Eberhardt M, Rammohan G.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Feb 16.

19.

Reactive metabolites of acetaminophen activate and sensitize the capsaicin receptor TRPV1.

Eberhardt MJ, Schillers F, Eberhardt EM, Risser L, de la Roche J, Herzog C, Echtermeyer F, Leffler A.

Sci Rep. 2017 Oct 6;7(1):12775. doi: 10.1038/s41598-017-13054-3.

20.

Depressive states among adults with diabetes: Findings from the National Health and Nutrition Examination Survey, 2007-2012.

Albertorio-Diaz JR, Eberhardt MS, Oquendo M, Mesa-Frias M, He Y, Jonas B, Kang K.

Diabetes Res Clin Pract. 2017 May;127:80-88. doi: 10.1016/j.diabres.2017.02.031. Epub 2017 Feb 27.

21.

Stimulation of rat cranial dura mater with potassium chloride causes CGRP release into the cerebrospinal fluid and increases medullary blood flow.

Dux M, Will C, Eberhardt M, Fischer MJM, Messlinger K.

Neuropeptides. 2017 Aug;64:61-68. doi: 10.1016/j.npep.2017.02.080. Epub 2017 Feb 10.

PMID:
28202186
22.

An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data.

Wentker P, Eberhardt M, Dreyer FS, Bertrams W, Cantone M, Griss K, Schmeck B, Vera J.

J Immunol. 2017 Mar 1;198(5):2191-2201. doi: 10.4049/jimmunol.1502513. Epub 2017 Jan 30.

23.

Epigenetic divergence in the TRPA1 promoter correlates with pressure pain thresholds in healthy individuals.

Gombert S, Rhein M, Eberhardt M, Münster T, Bleich S, Leffler A, Frieling H.

Pain. 2017 Apr;158(4):698-704. doi: 10.1097/j.pain.0000000000000815.

PMID:
28030472
24.

Lactate is a potent inhibitor of the capsaicin receptor TRPV1.

de la Roche J, Walther I, Leonow W, Hage A, Eberhardt M, Fischer M, Reeh PW, Sauer S, Leffler A.

Sci Rep. 2016 Nov 9;6:36740. doi: 10.1038/srep36740.

25.

Hepatitis E in blood donors: investigation of the natural course of asymptomatic infection, Germany, 2011.

Vollmer T, Diekmann J, Eberhardt M, Knabbe C, Dreier J.

Euro Surveill. 2016 Sep 1;21(35). doi: 10.2807/1560-7917.ES.2016.21.35.30332.

26.

Exploitation of Interleukin-10 (IL-10) Signaling Pathways: Alternate Roles of Viral and Cellular IL-10 in Rhesus Cytomegalovirus Infection.

Eberhardt MK, Deshpande A, Fike J, Short R, Schmidt KA, Blozis SA, Walter MR, Barry PA.

J Virol. 2016 Oct 14;90(21):9920-9930. doi: 10.1128/JVI.00635-16. Print 2016 Nov 1.

27.
28.

Trends in Prevalence of Chronic Kidney Disease in the United States.

Murphy D, McCulloch CE, Lin F, Banerjee T, Bragg-Gresham JL, Eberhardt MS, Morgenstern H, Pavkov ME, Saran R, Powe NR, Hsu CY; Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team.

Ann Intern Med. 2016 Oct 4;165(7):473-481. doi: 10.7326/M16-0273. Epub 2016 Aug 2.

29.

Propacetamol-Induced Injection Pain Is Associated with Activation of Transient Receptor Potential Vanilloid 1 Channels.

Schillers F, Eberhardt E, Leffler A, Eberhardt M.

J Pharmacol Exp Ther. 2016 Oct;359(1):18-25. doi: 10.1124/jpet.116.233452. Epub 2016 Jul 25.

PMID:
27457427
30.

[Pain and analgesia : Mutations of voltage-gated sodium channels].

Eberhardt MJ, Leffler A.

Schmerz. 2017 Feb;31(1):14-22. doi: 10.1007/s00482-016-0139-0. German.

PMID:
27402262
31.

Local-anesthetic like inhibition of the cardiac sodium channel Nav1.5 α-subunit by 5-HT3 receptor antagonists.

Van't Klooster MP, Foadi N, Hage A, Stoetzer C, Wegner F, Eberhardt M, Leffler A.

Eur J Pharmacol. 2016 Oct 15;789:119-126. doi: 10.1016/j.ejphar.2016.07.020. Epub 2016 Jul 9.

PMID:
27401036
32.

Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity.

Moparthi L, Kichko TI, Eberhardt M, Högestätt ED, Kjellbom P, Johanson U, Reeh PW, Leffler A, Filipovic MR, Zygmunt PM.

Sci Rep. 2016 Jun 28;6:28763. doi: 10.1038/srep28763.

33.

Genome-wide Chromatin Profiling of Legionella pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2.

Du Bois I, Marsico A, Bertrams W, Schweiger MR, Caffrey BE, Sittka-Stark A, Eberhardt M, Vera J, Vingron M, Schmeck BT.

J Infect Dis. 2016 Aug 1;214(3):454-63. doi: 10.1093/infdis/jiw171. Epub 2016 Apr 29.

PMID:
27130431
34.

Model-based genotype-phenotype mapping used to investigate gene signatures of immune sensitivity and resistance in melanoma micrometastasis.

Santos G, Nikolov S, Lai X, Eberhardt M, Dreyer FS, Paul S, Schuler G, Vera J.

Sci Rep. 2016 Apr 26;6:24967. doi: 10.1038/srep24967.

35.

MicroRNAs Constitute a Negative Feedback Loop in Streptococcus pneumoniae-Induced Macrophage Activation.

Griss K, Bertrams W, Sittka-Stark A, Seidel K, Stielow C, Hippenstiel S, Suttorp N, Eberhardt M, Wilhelm J, Vera J, Schmeck B.

J Infect Dis. 2016 Jul 15;214(2):288-99. doi: 10.1093/infdis/jiw109. Epub 2016 Mar 16.

PMID:
26984146
36.

Reduced sensitivity to context in language comprehension: A characteristic of Autism Spectrum Disorders or of poor structural language ability?

Eberhardt M, Nadig A.

Res Dev Disabil. 2018 Jan;72:284-296. doi: 10.1016/j.ridd.2016.01.017. Epub 2016 Feb 18.

37.

Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity.

Stueber T, Eberhardt MJ, Hadamitzky C, Jangra A, Schenk S, Dick F, Stoetzer C, Kistner K, Reeh PW, Binshtok AM, Leffler A.

Anesthesiology. 2016 May;124(5):1153-65. doi: 10.1097/ALN.0000000000001050.

PMID:
26859646
38.

Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive.

Eberhardt M, Lai X, Tomar N, Gupta S, Schmeck B, Steinkasserer A, Schuler G, Vera J.

Methods Mol Biol. 2016;1386:135-79. doi: 10.1007/978-1-4939-3283-2_9. Review.

PMID:
26677184
39.
40.

An uncommon complication of hyperosmolar hyperglycemic state: bilateral above knee amputations.

Milano A, Tadevosyan A, Hart R, Luizza A, Eberhardt M.

Am J Emerg Med. 2016 Feb;34(2):341.e1-2. doi: 10.1016/j.ajem.2015.06.023. Epub 2015 Jun 16. No abstract available.

PMID:
26184523
41.

The interplay between immune maturation, age, chronic viral infection and environment.

Oxford KL, Dela Pena-Ponce MGA, Jensen K, Eberhardt MK, Spinner A, Van Rompay KK, Rigdon J, Mollan KR, Krishnan VV, Hudgens MG, Barry PA, De Paris K.

Immun Ageing. 2015 May 9;12:3. doi: 10.1186/s12979-015-0030-3. eCollection 2015.

42.

Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE.

Andersson DA, Filipović MR, Gentry C, Eberhardt M, Vastani N, Leffler A, Reeh P, Bevan S.

J Biol Chem. 2015 Jun 12;290(24):15185-96. doi: 10.1074/jbc.M115.644476. Epub 2015 Apr 22.

43.

Diabetes and fracture risk in older U.S. adults.

Looker AC, Eberhardt MS, Saydah SH.

Bone. 2016 Jan;82:9-15. doi: 10.1016/j.bone.2014.12.008. Epub 2015 Jan 7.

44.

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway.

Eberhardt M, Dux M, Namer B, Miljkovic J, Cordasic N, Will C, Kichko TI, de la Roche J, Fischer M, Suárez SA, Bikiel D, Dorsch K, Leffler A, Babes A, Lampert A, Lennerz JK, Jacobi J, Martí MA, Doctorovich F, Högestätt ED, Zygmunt PM, Ivanovic-Burmazovic I, Messlinger K, Reeh P, Filipovic MR.

Nat Commun. 2014 Jul 15;5:4381. doi: 10.1038/ncomms5381.

45.

Pathogen manipulation of cIL-10 signaling pathways: opportunities for vaccine development?

Eberhardt MK, Barry PA.

Curr Top Microbiol Immunol. 2014;380:93-128. doi: 10.1007/978-3-662-43492-5_5. Review.

PMID:
25004815
46.

Altered sodium channel gating as molecular basis for pain: contribution of activation, inactivation, and resurgent currents.

Lampert A, Eberhardt M, Waxman SG.

Handb Exp Pharmacol. 2014;221:91-110. doi: 10.1007/978-3-642-41588-3_5. Review.

PMID:
24737233
47.

HCN2 channels account for mechanical (but not heat) hyperalgesia during long-standing inflammation.

Schnorr S, Eberhardt M, Kistner K, Rajab H, Käßer J, Hess A, Reeh P, Ludwig A, Herrmann S.

Pain. 2014 Jun;155(6):1079-90. doi: 10.1016/j.pain.2014.02.006. Epub 2014 Feb 10.

PMID:
24525276
48.

Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.

Eberhardt M, Nakajima J, Klinger AB, Neacsu C, Hühne K, O'Reilly AO, Kist AM, Lampe AK, Fischer K, Gibson J, Nau C, Winterpacht A, Lampert A.

J Biol Chem. 2014 Jan 24;289(4):1971-80. doi: 10.1074/jbc.M113.502211. Epub 2013 Dec 5.

49.

Recombinant production, crystallization and preliminary structural characterization of Schistosoma japonicum profilin.

Vervaet N, Kallio JP, Meier S, Salmivaara E, Eberhardt M, Zhang S, Sun X, Wu Z, Kursula P, Kursula I.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1264-7. doi: 10.1107/S174430911302647X. Epub 2013 Oct 30.

50.

Vaccination against a virus-encoded cytokine significantly restricts viral challenge.

Eberhardt MK, Deshpande A, Chang WL, Barthold SW, Walter MR, Barry PA.

J Virol. 2013 Nov;87(21):11323-31. doi: 10.1128/JVI.01925-13. Epub 2013 Aug 14.

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