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Items: 25

1.

Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist.

McKeown MR, Corces MR, Eaton ML, Fiore C, Lee E, Lopez JT, Chen MW, Smith D, Chan SM, Koenig JL, Austgen K, Guenther MG, Orlando DA, Lovén J, Fritz CC, Majeti R.

Cancer Discov. 2017 Oct;7(10):1136-1153. doi: 10.1158/2159-8290.CD-17-0399. Epub 2017 Jul 20.

2.

Noncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant Cells.

Feng J, Gan H, Eaton ML, Zhou H, Li S, Belsky JA, MacAlpine DM, Zhang Z, Li Q.

Mol Cell Biol. 2016 Jun 15;36(13):1856-67. doi: 10.1128/MCB.00152-16. Print 2016 Jul 1.

3.

Alzheimer's loci: epigenetic associations and interaction with genetic factors.

Chibnik LB, Yu L, Eaton ML, Srivastava G, Schneider JA, Kellis M, Bennett DA, De Jager PL.

Ann Clin Transl Neurol. 2015 Jun;2(6):636-47. doi: 10.1002/acn3.201. Epub 2015 Apr 24.

4.

BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.

Hatchi E, Skourti-Stathaki K, Ventz S, Pinello L, Yen A, Kamieniarz-Gdula K, Dimitrov S, Pathania S, McKinney KM, Eaton ML, Kellis M, Hill SJ, Parmigiani G, Proudfoot NJ, Livingston DM.

Mol Cell. 2015 Feb 19;57(4):636-647. doi: 10.1016/j.molcel.2015.01.011.

5.

Integrative analysis of 111 reference human epigenomes.

Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M.

Nature. 2015 Feb 19;518(7539):317-30. doi: 10.1038/nature14248.

6.

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.

De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA.

Nat Neurosci. 2014 Sep;17(9):1156-63. doi: 10.1038/nn.3786. Epub 2014 Aug 17.

7.

Money and morals: ending clinical trials for financial reasons.

Eaton ML, Kwon BK, Scott CT.

Curr Top Behav Neurosci. 2015;19:297-315. doi: 10.1007/7854_2014_337. Review.

PMID:
25062706
8.

Developmental control of gene copy number by repression of replication initiation and fork progression.

Sher N, Bell GW, Li S, Nordman J, Eng T, Eaton ML, Macalpine DM, Orr-Weaver TL.

Genome Res. 2012 Jan;22(1):64-75. doi: 10.1101/gr.126003.111. Epub 2011 Nov 16.

9.

A cis-regulatory map of the Drosophila genome.

Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li Z, Ishii H, Spokony RF, Chen J, Hwang L, Cheng C, Auburn RP, Davis MB, Domanus M, Shah PK, Morrison CA, Zieba J, Suchy S, Senderowicz L, Victorsen A, Bild NA, Grundstad AJ, Hanley D, MacAlpine DM, Mannervik M, Venken K, Bellen H, White R, Gerstein M, Russell S, Grossman RL, Ren B, Posakony JW, Kellis M, White KP.

Nature. 2011 Mar 24;471(7339):527-31. doi: 10.1038/nature09990.

10.

Identification of functional elements and regulatory circuits by Drosophila modENCODE.

modENCODE Consortium, Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, Robine N, Washington NL, Di Stefano L, Berezikov E, Brown CD, Candeias R, Carlson JW, Carr A, Jungreis I, Marbach D, Sealfon R, Tolstorukov MY, Will S, Alekseyenko AA, Artieri C, Booth BW, Brooks AN, Dai Q, Davis CA, Duff MO, Feng X, Gorchakov AA, Gu T, Henikoff JG, Kapranov P, Li R, MacAlpine HK, Malone J, Minoda A, Nordman J, Okamura K, Perry M, Powell SK, Riddle NC, Sakai A, Samsonova A, Sandler JE, Schwartz YB, Sher N, Spokony R, Sturgill D, van Baren M, Wan KH, Yang L, Yu C, Feingold E, Good P, Guyer M, Lowdon R, Ahmad K, Andrews J, Berger B, Brenner SE, Brent MR, Cherbas L, Elgin SC, Gingeras TR, Grossman R, Hoskins RA, Kaufman TC, Kent W, Kuroda MI, Orr-Weaver T, Perrimon N, Pirrotta V, Posakony JW, Ren B, Russell S, Cherbas P, Graveley BR, Lewis S, Micklem G, Oliver B, Park PJ, Celniker SE, Henikoff S, Karpen GH, Lai EC, MacAlpine DM, Stein LD, White KP, Kellis M.

Science. 2010 Dec 24;330(6012):1787-97. doi: 10.1126/science.1198374. Epub 2010 Dec 22.

11.

Chromatin signatures of the Drosophila replication program.

Eaton ML, Prinz JA, MacAlpine HK, Tretyakov G, Kharchenko PV, MacAlpine DM.

Genome Res. 2011 Feb;21(2):164-74. doi: 10.1101/gr.116038.110. Epub 2010 Dec 22.

12.

WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration.

Dwyer MA, Joseph JD, Wade HE, Eaton ML, Kunder RS, Kazmin D, Chang CY, McDonnell DP.

Cancer Res. 2010 Nov 15;70(22):9298-308. doi: 10.1158/0008-5472.CAN-10-0226. Epub 2010 Sep 24.

13.

The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin.

Müller P, Park S, Shor E, Huebert DJ, Warren CL, Ansari AZ, Weinreich M, Eaton ML, MacAlpine DM, Fox CA.

Genes Dev. 2010 Jul 1;24(13):1418-33. doi: 10.1101/gad.1906410.

14.

Conserved nucleosome positioning defines replication origins.

Eaton ML, Galani K, Kang S, Bell SP, MacAlpine DM.

Genes Dev. 2010 Apr 15;24(8):748-53. doi: 10.1101/gad.1913210. Epub 2010 Mar 29.

15.

Multimodal regulation of E2F1 gene expression by progestins.

Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP.

Mol Cell Biol. 2010 Apr;30(8):1866-77. doi: 10.1128/MCB.01060-09. Epub 2010 Feb 1.

16.

Commercializing cognitive neurotechnology--the ethical terrain.

Eaton ML, Illes J.

Nat Biotechnol. 2007 Apr;25(4):393-7. No abstract available.

PMID:
17420741
17.

Surrogate decision making for genetic testing for Alzheimer disease.

Eaton ML.

Genet Test. 1999;3(1):93-7. Review.

PMID:
10464582
18.

Hospitalizations for painful episodes: association with school absenteeism and academic performance in children and adolescents with sickle cell anemia.

Eaton ML, Haye JS, Armstrong FD, Pegelow CH, Thomas M.

Issues Compr Pediatr Nurs. 1995 Jan-Mar;18(1):1-9.

PMID:
8707636
19.

Assessing differential drug effect.

Berry DA, Eaton ML, Ekholm BP, Fox TL.

Biometrics. 1984 Dec;40(4):1109-15.

PMID:
6398711
20.

Isotretinoin in severe, recalcitrant cystic acne: a review.

Rumsfield JA, West DP, Tse CS, Eaton ML, Robinson LA.

Drug Intell Clin Pharm. 1983 May;17(5):329-33. Review.

PMID:
6222891
21.

Effects of theophylline on breathlessness and exercise tolerance in patients with chronic airflow obstruction.

Eaton ML, MacDonald FM, Church TR, Niewoehner DE.

Chest. 1982 Nov;82(5):538-42.

PMID:
7128220
22.

Efficacy of theophylline in "irreversible" airflow obstruction.

Eaton ML, Green BA, Church TR, McGowan T, Niewoehner DE.

Ann Intern Med. 1980 Jun;92(6):758-61.

PMID:
7387018
23.

Patient comprehension of written drug information.

Eaton ML, Holloway RL.

Am J Hosp Pharm. 1980 Feb;37(2):240-3.

PMID:
7361799
24.

Chronic hypervitaminosis A.

Eaton ML.

Am J Hosp Pharm. 1978 Sep;35(9):1099-102.

PMID:
696755
25.

A validity study using the Leighton instrument.

Moses LE, Goldfarb A, Glock CY, Stark RW, Eaton ML.

Am J Public Health. 1971 Sep;61(9):1785-93. No abstract available.

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