Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 179


Public Health Consequences of e-Cigarette Use.

St Helen G, Eaton DL.

JAMA Intern Med. 2018 Jul 1;178(7):984-986. doi: 10.1001/jamainternmed.2018.1600. Review. No abstract available.


Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.

Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL.

JCI Insight. 2017 Nov 16;2(22). pii: 95978. doi: 10.1172/jci.insight.95978. eCollection 2017 Nov 16.


Microphysiological Systems to Assess Nonclinical Toxicity.

Van Ness KP, Chang SY, Weber EJ, Zumpano D, Eaton DL, Kelly EJ.

Curr Protoc Toxicol. 2017 Aug 4;73:14.18.1-14.18.28. doi: 10.1002/cptx.27.


Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.

Chang SY, Voellinger JL, Van Ness KP, Chapron B, Shaffer RM, Neumann T, White CC, Kavanagh TJ, Kelly EJ, Eaton DL.

Toxicol In Vitro. 2017 Apr;40:170-183. doi: 10.1016/j.tiv.2017.01.007. Epub 2017 Jan 13.


Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function.

Chang SY, Weber EJ, Ness KV, Eaton DL, Kelly EJ.

Clin Pharmacol Ther. 2016 Nov;100(5):464-478. doi: 10.1002/cpt.436. Epub 2016 Aug 27. Review.


Unliganded fibroblast growth factor receptor 1 forms density-independent dimers.

Comps-Agrar L, Dunshee DR, Eaton DL, Sonoda J.

J Biol Chem. 2015 Oct 2;290(40):24166-77. doi: 10.1074/jbc.M115.681395. Epub 2015 Aug 13.


Mortalin is Expressed by Astrocytes and Decreased in the Midbrain of Parkinson's Disease Patients.

Cook TJ, Hoekstra JG, Eaton DL, Zhang J.

Brain Pathol. 2016 Jan;26(1):75-81. doi: 10.1111/bpa.12274. Epub 2015 Jul 27.


The NIEHS Superfund Research Program: 25 Years of Translational Research for Public Health.

Landrigan PJ, Wright RO, Cordero JF, Eaton DL, Goldstein BD, Hennig B, Maier RM, Ozonoff DM, Smith MT, Tukey RH.

Environ Health Perspect. 2015 Oct;123(10):909-18. doi: 10.1289/ehp.1409247. Epub 2015 May 15.


FutureTox II: in vitro data and in silico models for predictive toxicology.

Knudsen TB, Keller DA, Sander M, Carney EW, Doerrer NG, Eaton DL, Fitzpatrick SC, Hastings KL, Mendrick DL, Tice RR, Watkins PB, Whelan M.

Toxicol Sci. 2015 Feb;143(2):256-67. doi: 10.1093/toxsci/kfu234.


The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function.

Johnston RJ, Comps-Agrar L, Hackney J, Yu X, Huseni M, Yang Y, Park S, Javinal V, Chiu H, Irving B, Eaton DL, Grogan JL.

Cancer Cell. 2014 Dec 8;26(6):923-937. doi: 10.1016/j.ccell.2014.10.018. Epub 2014 Nov 26.


Cruciferous vegetables have variable effects on biomarkers of systemic inflammation in a randomized controlled trial in healthy young adults.

Navarro SL, Schwarz Y, Song X, Wang CY, Chen C, Trudo SP, Kristal AR, Kratz M, Eaton DL, Lampe JW.

J Nutr. 2014 Nov;144(11):1850-7. doi: 10.3945/jn.114.197434. Epub 2014 Aug 27.


In vitro approaches to assessing the toxicity of quantum dots.

McMahan RS, Lee V, Parks WC, Kavanagh TJ, Eaton DL.

Methods Mol Biol. 2014;1199:155-63. doi: 10.1007/978-1-4939-1280-3_12.


Amphiphilic polymer-coated CdSe/ZnS quantum dots induce pro-inflammatory cytokine expression in mouse lung epithelial cells and macrophages.

Lee V, McMahan RS, Hu X, Gao X, Faustman EM, Griffith WC, Kavanagh TJ, Eaton DL, McGuire JK, Parks WC.

Nanotoxicology. 2015 May;9(3):336-43. doi: 10.3109/17435390.2014.930532. Epub 2014 Jul 1.


Of mice, rats, and men: could Nrf2 activation protect against aflatoxin heptocarcinogenesis in humans?

Eaton DL, Schaupp CM.

Cancer Prev Res (Phila). 2014 Jul;7(7):653-7. doi: 10.1158/1940-6207.CAPR-14-0119. Epub 2014 Jun 16.


Mechanism for neutralizing activity by the anti-CMV gH/gL monoclonal antibody MSL-109.

Fouts AE, Comps-Agrar L, Stengel KF, Ellerman D, Schoeffler AJ, Warming S, Eaton DL, Feierbach B.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8209-14. doi: 10.1073/pnas.1404653111. Epub 2014 May 19.


Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system.

Kelly EJ, Wang Z, Voellinger JL, Yeung CK, Shen DD, Thummel KE, Zheng Y, Ligresti G, Eaton DL, Muczynski KA, Duffield JS, Neumann T, Tourovskaia A, Fauver M, Kramer G, Asp E, Himmelfarb J.

Stem Cell Res Ther. 2013;4 Suppl 1:S17. doi: 10.1186/scrt378. Epub 2013 Dec 20. Review.


The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice.

McConnachie LA, Botta D, White CC, Weldy CS, Wilkerson HW, Yu J, Dills R, Yu X, Griffith WC, Faustman EM, Farin FM, Gill SE, Parks WC, Hu X, Gao X, Eaton DL, Kavanagh TJ.

PLoS One. 2013 May 27;8(5):e64165. doi: 10.1371/journal.pone.0064165. Print 2013.


Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalacia.

Wang Z, Lin YS, Dickmann LJ, Poulton EJ, Eaton DL, Lampe JW, Shen DD, Davis CL, Shuhart MC, Thummel KE.

J Bone Miner Res. 2013 May;28(5):1101-16. doi: 10.1002/jbmr.1839.


Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo.

Poulton EJ, Levy L, Lampe JW, Shen DD, Tracy J, Shuhart MC, Thummel KE, Eaton DL.

Toxicol Appl Pharmacol. 2013 Jan 1;266(1):122-31. doi: 10.1016/j.taap.2012.10.029. Epub 2012 Nov 12.


In vitro toxicity assessment of amphiphillic polymer-coated CdSe/ZnS quantum dots in two human liver cell models.

Smith WE, Brownell J, White CC, Afsharinejad Z, Tsai J, Hu X, Polyak SJ, Gao X, Kavanagh TJ, Eaton DL.

ACS Nano. 2012 Nov 27;6(11):9475-84. doi: 10.1021/nn302288r. Epub 2012 Oct 18.


Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1).

Gross-Steinmeyer K, Eaton DL.

Toxicology. 2012 Sep 28;299(2-3):69-79. doi: 10.1016/j.tox.2012.05.016. Epub 2012 May 26. Review.


Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.

Stengel KF, Harden-Bowles K, Yu X, Rouge L, Yin J, Comps-Agrar L, Wiesmann C, Bazan JF, Eaton DL, Grogan JL.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5399-404. doi: 10.1073/pnas.1120606109. Epub 2012 Mar 15.


Heme oxygenase expression as a biomarker of exposure to amphiphilic polymer-coated CdSe/ZnS quantum dots.

McConnachie LA, White CC, Botta D, Zadworny ME, Cox DP, Beyer RP, Hu X, Eaton DL, Gao X, Kavanagh TJ.

Nanotoxicology. 2013 Mar;7(2):181-91. doi: 10.3109/17435390.2011.648224. Epub 2012 Jan 20.


Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression.

Gross-Steinmeyer K, Stapleton PL, Tracy JH, Bammler TK, Strom SC, Eaton DL.

Toxicol Sci. 2010 Aug;116(2):422-32. doi: 10.1093/toxsci/kfq135. Epub 2010 May 4.


CYP1A2, GSTM1, and GSTT1 polymorphisms and diet effects on CYP1A2 activity in a crossover feeding trial.

Peterson S, Schwarz Y, Li SS, Li L, King IB, Chen C, Eaton DL, Potter JD, Lampe JW.

Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3118-25. doi: 10.1158/1055-9965.EPI-09-0589. Epub 2009 Oct 20.


Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols.

Gross-Steinmeyer K, Stapleton PL, Tracy JH, Bammler TK, Strom SC, Buhler DR, Eaton DL.

Toxicol Sci. 2009 Dec;112(2):303-10. doi: 10.1093/toxsci/kfp206. Epub 2009 Sep 21.


Identification of glutathione S-transferase pi as a protein involved in Parkinson disease progression.

Shi M, Bradner J, Bammler TK, Eaton DL, Zhang J, Ye Z, Wilson AM, Montine TJ, Pan C, Zhang J.

Am J Pathol. 2009 Jul;175(1):54-65. doi: 10.2353/ajpath.2009.081019. Epub 2009 Jun 4.


B and T lymphocyte attenuator regulates B cell receptor signaling by targeting Syk and BLNK.

Vendel AC, Calemine-Fenaux J, Izrael-Tomasevic A, Chauhan V, Arnott D, Eaton DL.

J Immunol. 2009 Feb 1;182(3):1509-17.


Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment.

Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, Coyle J, McKhann G, Mobley WC, Nadel L, Neubert D, Schulte-Hermann R, Spencer PS.

Crit Rev Toxicol. 2008;38 Suppl 2:1-125. doi: 10.1080/10408440802272158 . Review.


Serum organochlorine pesticide residues and risk of testicular germ cell carcinoma: a population-based case-control study.

Biggs ML, Davis MD, Eaton DL, Weiss NS, Barr DB, Doody DR, Fish S, Needham LL, Chen C, Schwartz SM.

Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2012-8. doi: 10.1158/1055-9965.EPI-08-0032.


The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor.

Zhou C, Poulton EJ, GrĂ¼n F, Bammler TK, Blumberg B, Thummel KE, Eaton DL.

Mol Pharmacol. 2007 Jan;71(1):220-9. Epub 2006 Oct 6.


5' and 3' region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating study.

Kelada SN, Checkoway H, Kardia SL, Carlson CS, Costa-Mallen P, Eaton DL, Firestone J, Powers KM, Swanson PD, Franklin GM, Longstreth WT Jr, Weller TS, Afsharinejad Z, Costa LG.

Hum Mol Genet. 2006 Oct 15;15(20):3055-62. Epub 2006 Sep 8.


Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1.

Peterson S, Lampe JW, Bammler TK, Gross-Steinmeyer K, Eaton DL.

Food Chem Toxicol. 2006 Sep;44(9):1474-84. Epub 2006 Apr 27.


Genetic Susceptibility to Prostate Cancer: Prostate-specific Antigen and its Interaction with the Androgen Receptor (United States).

Sieh W, Edwards KL, Fitzpatrick AL, Srinouanprachanh SL, Farin FM, Monks SA, Kronmal RA, Eaton DL.

Cancer Causes Control. 2006 Mar;17(2):187-97.


Analysis of cellular responses to aflatoxin B(1) in yeast expressing human cytochrome P450 1A2 using cDNA microarrays.

Guo Y, Breeden LL, Fan W, Zhao LP, Eaton DL, Zarbl H.

Mutat Res. 2006 Jan 29;593(1-2):121-42. Epub 2005 Aug 24.


Influence of Matrigel-overlay on constitutive and inducible expression of nine genes encoding drug-metabolizing enzymes in primary human hepatocytes.

Gross-Steinmeyer K, Stapleton PL, Tracy JH, Bammler TK, Lehman T, Strom SC, Eaton DL.

Xenobiotica. 2005 May;35(5):419-38.


Glutathione S-transferases as putative host susceptibility genes for cancer risk in agricultural workers.

Eaton DL.

J Biochem Mol Toxicol. 2005;19(3):187-9. No abstract available.


Proteomic profiling of surface proteins on Th1 and Th2 cells.

Loyet KM, Ouyang W, Eaton DL, Stults JT.

J Proteome Res. 2005 Mar-Apr;4(2):400-9.


Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes.

Gross-Steinmeyer K, Stapleton PL, Liu F, Tracy JH, Bammler TK, Quigley SD, Farin FM, Buhler DR, Safe SH, Strom SC, Eaton DL.

Xenobiotica. 2004 Jul;34(7):619-32.


A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator.

Gonzalez LC, Loyet KM, Calemine-Fenaux J, Chauhan V, Wranik B, Ouyang W, Eaton DL.

Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1116-21. Epub 2005 Jan 12.


Estradiol metabolites as isoform-specific inhibitors of human glutathione S-transferases.

Abel EL, Lyon RP, Bammler TK, Verlinde CL, Lau SS, Monks TJ, Eaton DL.

Chem Biol Interact. 2004 Dec 30;151(1):21-32.


Characterization of atrazine biotransformation by human and murine glutathione S-transferases.

Abel EL, Opp SM, Verlinde CL, Bammler TK, Eaton DL.

Toxicol Sci. 2004 Aug;80(2):230-8. Epub 2004 Apr 28.


Biotransformation of methyl parathion by glutathione S-transferases.

Abel EL, Bammler TK, Eaton DL.

Toxicol Sci. 2004 Jun;79(2):224-32. Epub 2004 Apr 21.


Tellurium-mediated cycloaromatization of acyclic enediynes under mild conditions.

Landis CA, Payne MM, Eaton DL, Anthony JE.

J Am Chem Soc. 2004 Feb 11;126(5):1338-9.


The role of genetic polymorphisms in environmental health.

Kelada SN, Eaton DL, Wang SS, Rothman NR, Khoury MJ.

Environ Health Perspect. 2003 Jun;111(8):1055-64. Review.


Glutathione S-transferase M1, T1, and P1 polymorphisms and survival among lung cancer patients.

Sweeney C, Nazar-Stewart V, Stapleton PL, Eaton DL, Vaughan TL.

Cancer Epidemiol Biomarkers Prev. 2003 Jun;12(6):527-33.


A population-based study of glutathione S-transferase M1, T1 and P1 genotypes and risk for lung cancer.

Nazar-Stewart V, Vaughan TL, Stapleton P, Van Loo J, Nicol-Blades B, Eaton DL.

Lung Cancer. 2003 Jun;40(3):247-58.


Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's disease.

Kelada SN, Stapleton PL, Farin FM, Bammler TK, Eaton DL, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT Jr, Checkoway H.

Neurosci Lett. 2003 Jan 30;337(1):5-8.


Supplemental Content

Loading ...
Support Center