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Discovery of Indole- and Indazole-Acylsulfonamides as Potent and Selective NaV1.7 Inhibitors for the Treatment of Pain.

Luo G, Chen L, Easton A, Newton A, Bourin C, Shields E, Mosure K, Soars MG, Knox RJ, Matchett M, Pieschl RL, Post-Munson D, Wang S, Herrington J, Graef J, Newberry K, Sivarao DV, Senapati A, Bristow L, Meanwell NA, Thompson LA, Dzierba CD.

J Med Chem. 2018 Dec 21. doi: 10.1021/acs.jmedchem.8b01550. [Epub ahead of print]


Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS.

Sengupta-Ghosh A, Dominguez SL, Xie L, Barck KH, Jiang Z, Earr T, Imperio J, Phu L, Budayeva HG, Kirkpatrick DS, Cai H, Eastham-Anderson J, Ngu H, Foreman O, Hedehus M, Reichelt M, Hotzel I, Shang Y, Carano RAD, Ayalon G, Easton A.

Neurobiol Dis. 2018 Dec 4;124:340-352. doi: 10.1016/j.nbd.2018.12.002. [Epub ahead of print]


A pragmatic cluster randomised controlled trial of a tailored intervention to improve the initial management of suspected encephalitis.

Backman R, Foy R, Diggle PJ, Kneen R, Easton A, Defres S, McGill F, Michael BD, Solomon T; ENCEPH UK Programme Steering Committee.

PLoS One. 2018 Dec 6;13(12):e0202257. doi: 10.1371/journal.pone.0202257. eCollection 2018.


Continual Trials Spontaneous Recognition Tasks in Mice: Reducing Animal Numbers and Improving Our Understanding of the Mechanisms Underlying Memory.

Chan M, Eacott MJ, Sanderson DJ, Wang J, Sun M, Easton A.

Front Behav Neurosci. 2018 Sep 13;12:214. doi: 10.3389/fnbeh.2018.00214. eCollection 2018.


Walking through doorways differentially affects recall and familiarity.

Seel SV, Easton A, McGregor A, Buckley MG, Eacott MJ.

Br J Psychol. 2018 Sep 16. doi: 10.1111/bjop.12343. [Epub ahead of print]


Development of MGD007, a gpA33 x CD3-Bispecific DART Protein for T-Cell Immunotherapy of Metastatic Colorectal Cancer.

Moore PA, Shah K, Yang Y, Alderson R, Roberts P, Long V, Liu D, Li JC, Burke S, Ciccarone V, Li H, Fieger CB, Hooley J, Easton A, Licea M, Gorlatov S, King KL, Young P, Adami A, Loo D, Chichili GR, Liu L, Smith DH, Brown JG, Chen FZ, Koenig S, Mather J, Bonvini E, Johnson S.

Mol Cancer Ther. 2018 Aug;17(8):1761-1772. doi: 10.1158/1535-7163.MCT-17-1086. Epub 2018 Jun 4.


Taxonomy of the order Mononegavirales: update 2018.

Amarasinghe GK, Aréchiga Ceballos NG, Banyard AC, Basler CF, Bavari S, Bennett AJ, Blasdell KR, Briese T, Bukreyev A, Caì Y, Calisher CH, Campos Lawson C, Chandran K, Chapman CA, Chiu CY, Choi KS, Collins PL, Dietzgen RG, Dolja VV, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Echevarría JE, Fooks AR, Formenty PBH, Fouchier RAM, Freuling CM, Ghedin E, Goldberg TL, Hewson R, Horie M, Hyndman TH, Jiāng D, Kityo R, Kobinger GP, Kondō H, Koonin EV, Krupovic M, Kurath G, Lamb RA, Lee B, Leroy EM, Maes P, Maisner A, Marston DA, Mor SK, Müller T, Mühlberger E, Ramírez VMN, Netesov SV, Ng TFF, Nowotny N, Palacios G, Patterson JL, Pawęska JT, Payne SL, Prieto K, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Siddell S, Smither SJ, Song Q, Song T, Stenglein MD, Stone DM, Takada A, Tesh RB, Thomazelli LM, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Vázquez-Morón S, Verdugo C, Volchkov VE, Wahl V, Walker PJ, Wang D, Wang LF, Wellehan JFX, Wiley MR, Whitfield AE, Wolf YI, Yè G, Zhāng YZ, Kuhn JH.

Arch Virol. 2018 Aug;163(8):2283-2294. doi: 10.1007/s00705-018-3814-x. Epub 2018 Apr 11.


Evidence for Cholinergic Dysfunction in Autosomal Dominant Kufs Disease.

Jarrett P, Easton A, Rockwood K, Dyack S, McCollum A, Siu V, Mirsattari SM, Massot-Tarrús A, Beis MJ, D'Souza N, Darvesh S.

Can J Neurol Sci. 2018 Mar;45(2):150-157. doi: 10.1017/cjn.2017.261.


Increasing understanding of encephalitis.

Easton A.

Lancet Neurol. 2018 Apr;17(4):301. doi: 10.1016/S1474-4422(18)30077-2. Epub 2018 Feb 21. No abstract available.


Focal Cortical Dysplasia Type IIIb with Oligodendroglioma in a Seizure-Free Patient.

MacLean MA, Easton AS, Pickett GE.

Can J Neurol Sci. 2018 May;45(3):360-362. doi: 10.1017/cjn.2017.295. Epub 2018 Feb 12. No abstract available.


The optimal timing of post-treatment sampling for the assessment of anthelminthic drug efficacy against Ascaris infections in humans.

Levecke B, Easton AV, Cools P, Albonico M, Ame S, Gilleard JS, Keiser J, Montresor A, Prichard R, Vlaminck J, Vercruysse J.

Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):67-69. doi: 10.1016/j.ijpddr.2017.12.004. Epub 2018 Jan 13.


Problems of classification in the family Paramyxoviridae.

Rima B, Collins P, Easton A, Fouchier R, Kurath G, Lamb RA, Lee B, Maisner A, Rota P, Wang LF.

Arch Virol. 2018 May;163(5):1395-1404. doi: 10.1007/s00705-018-3720-2. Epub 2018 Jan 25.


Testing for soil-transmitted helminth transmission elimination: Analysing the impact of the sensitivity of different diagnostic tools.

Werkman M, Wright JE, Truscott JE, Easton AV, Oliveira RG, Toor J, Ower A, Ásbjörnsdóttir KH, Means AR, Farrell SH, Walson JL, Anderson RM.

PLoS Negl Trop Dis. 2018 Jan 18;12(1):e0006114. doi: 10.1371/journal.pntd.0006114. eCollection 2018 Jan.


Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis.

Warford JR, Lamport AC, Clements DR, Malone A, Kennedy BE, Kim Y, Gujar SA, Hoskin DW, Easton AS.

Acta Neuropathol Commun. 2018 Jan 4;6(1):4. doi: 10.1186/s40478-017-0506-9.


Can defective interfering RNAs affect the live attenuated influenza vaccine?

Dimmock NJ, Easton AJ.

Lancet Infect Dis. 2017 Dec;17(12):1234-1235. doi: 10.1016/S1473-3099(17)30637-0. No abstract available.


Comparative genome analysis of programmed DNA elimination in nematodes.

Wang J, Gao S, Mostovoy Y, Kang Y, Zagoskin M, Sun Y, Zhang B, White LK, Easton A, Nutman TB, Kwok PY, Hu S, Nielsen MK, Davis RE.

Genome Res. 2017 Dec;27(12):2001-2014. doi: 10.1101/gr.225730.117. Epub 2017 Nov 8.


ICTV Virus Taxonomy Profile: Pneumoviridae.

Rima B, Collins P, Easton A, Fouchier R, Kurath G, Lamb RA, Lee B, Maisner A, Rota P, Wang L, Ictv Report Consortium.

J Gen Virol. 2017 Dec;98(12):2912-2913. doi: 10.1099/jgv.0.000959. Epub 2017 Oct 31.


Live Attenuated Influenza Vaccine contains Substantial and Unexpected Amounts of Defective Viral Genomic RNA.

Gould PS, Easton AJ, Dimmock NJ.

Viruses. 2017 Sep 21;9(10). pii: E269. doi: 10.3390/v9100269.


Care beyond the hospital ward: understanding the socio-medical trajectory of herpes simplex virus encephalitis.

Cooper J, Kierans C, Defres S, Easton A, Kneen R, Solomon T; ENCEPH-UK study group.

BMC Health Serv Res. 2017 Sep 12;17(1):646. doi: 10.1186/s12913-017-2608-2.


Discovery of non-zwitterionic aryl sulfonamides as Nav1.7 inhibitors with efficacy in preclinical behavioral models and translational measures of nociceptive neuron activation.

Wu YJ, Guernon J, McClure A, Luo G, Rajamani R, Ng A, Easton A, Newton A, Bourin C, Parker D, Mosure K, Barnaby O, Soars MG, Knox RJ, Matchett M, Pieschl R, Herrington J, Chen P, Sivarao DV, Bristow LJ, Meanwell NA, Bronson J, Olson R, Thompson LA, Dzierba C.

Bioorg Med Chem. 2017 Oct 15;25(20):5490-5505. doi: 10.1016/j.bmc.2017.08.012. Epub 2017 Aug 9.


Unexpected complexity in the interference activity of a cloned influenza defective interfering RNA.

Meng B, Bentley K, Marriott AC, Scott PD, Dimmock NJ, Easton AJ.

Virol J. 2017 Jul 24;14(1):138. doi: 10.1186/s12985-017-0805-6.


Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain.

Vandersarren L, Bosteels C, Vanheerswynghels M, Moon JJ, Easton AJ, Van Isterdael G, Janssens S, Lambrecht BN, van Helden MJ.

Sci Rep. 2017 Jun 14;7(1):3472. doi: 10.1038/s41598-017-03042-y.


Cholinergic input to the hippocampus is not required for a model of episodic memory in the rat, even with multiple consecutive events.

Seel SV, Eacott MJ, Langston RF, Easton A.

Behav Brain Res. 2018 Nov 15;354:48-54. doi: 10.1016/j.bbr.2017.06.001. Epub 2017 Jun 7.


Sources of variability in the measurement of Ascaris lumbricoides infection intensity by Kato-Katz and qPCR.

Easton AV, Oliveira RG, Walker M, O'Connell EM, Njenga SM, Mwandawiro CS, Webster JP, Nutman TB, Anderson RM.

Parasit Vectors. 2017 May 25;10(1):256. doi: 10.1186/s13071-017-2164-y.


Social factors predictive of social integration for adults with brain injury.

Batchos E, Easton A, Haak C, Ditchman N.

Disabil Rehabil. 2018 Aug;40(17):2062-2069. doi: 10.1080/09638288.2017.1326175. Epub 2017 May 18.


Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents.

Pieschl RL, Miller R, Jones KM, Post-Munson DJ, Chen P, Newberry K, Benitex Y, Molski T, Morgan D, McDonald IM, Macor JE, Olson RE, Asaka Y, Digavalli S, Easton A, Herrington J, Westphal RS, Lodge NJ, Zaczek R, Bristow LJ, Li YW.

Eur J Pharmacol. 2017 Jul 15;807:1-11. doi: 10.1016/j.ejphar.2017.04.024. Epub 2017 Apr 22.


Factors impacting sense of community among adults with brain injury.

Ditchman N, Chan F, Haak C, Easton AB.

Rehabil Psychol. 2017 May;62(2):130-142. doi: 10.1037/rep0000139. Epub 2017 Apr 20.


Taxonomy of the order Mononegavirales: update 2017.

Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Fang Q, Formenty P, Fouchier RAM, Ghedin E, Harding RM, Hewson R, Higgins CM, Hong J, Horie M, James AP, Jiāng D, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lee B, Leroy EM, Li M, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Pearson MN, Randall RE, Revill PA, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Smither SJ, Song Q, Stone DM, Takada A, Terregino C, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang B, Wang D, Wang F, Wang LF, Werren JH, Whitfield AE, Yan Z, Ye G, Kuhn JH.

Arch Virol. 2017 Aug;162(8):2493-2504. doi: 10.1007/s00705-017-3311-7. Epub 2017 Apr 7.


Randomised controlled trial of ketamine augmentation of electroconvulsive therapy to improve neuropsychological and clinical outcomes in depression (Ketamine-ECT study).

Anderson IM, Blamire A, Branton T, Brigadoi S, Clark R, Downey D, Dunn G, Easton A, Elliott R, Elwell C, Hayden K, Holland F, Karim S, Lowe J, Loo C, Nair R, Oakley T, Prakash A, Sharma PK, Williams SR, McAllister-Williams RH.

Southampton (UK): NIHR Journals Library; 2017 Mar.


Ketamine augmentation of electroconvulsive therapy to improve neuropsychological and clinical outcomes in depression (Ketamine-ECT): a multicentre, double-blind, randomised, parallel-group, superiority trial.

Anderson IM, Blamire A, Branton T, Clark R, Downey D, Dunn G, Easton A, Elliott R, Elwell C, Hayden K, Holland F, Karim S, Loo C, Lowe J, Nair R, Oakley T, Prakash A, Sharma PK, Williams SR, McAllister-Williams RH; Ketamine-ECT Study team.

Lancet Psychiatry. 2017 May;4(5):365-377. doi: 10.1016/S2215-0366(17)30077-9. Epub 2017 Mar 27.


BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.

King D, Iwuagwu C, Cook J, McDonald IM, Mate R, Zusi FC, Hill MD, Fang H, Zhao R, Wang B, Easton AE, Miller R, Post-Munson D, Knox RJ, Gallagher L, Westphal R, Molski T, Fan J, Clarke W, Benitex Y, Lentz KA, Denton R, Morgan D, Zaczek R, Lodge NJ, Bristow LJ, Macor JE, Olson RE.

ACS Med Chem Lett. 2017 Feb 8;8(3):366-371. doi: 10.1021/acsmedchemlett.7b00032. eCollection 2017 Mar 9.


Encephalitis awareness.

Easton A.

Nurs Stand. 2017 Mar 1;31(27):30. doi: 10.7748/ns.31.27.30.s32.


Development of New Benzenesulfonamides As Potent and Selective Nav1.7 Inhibitors for the Treatment of Pain.

Wu YJ, Guernon J, Shi J, Ditta J, Robbins KJ, Rajamani R, Easton A, Newton A, Bourin C, Mosure K, Soars MG, Knox RJ, Matchett M, Pieschl RL, Post-Munson DJ, Wang S, Herrington J, Graef J, Newberry K, Bristow LJ, Meanwell NA, Olson R, Thompson LA, Dzierba C.

J Med Chem. 2017 Mar 23;60(6):2513-2525. doi: 10.1021/acs.jmedchem.6b01918. Epub 2017 Mar 10.


Symptom severity and life satisfaction in brain injury: The mediating role of disability acceptance and social self-efficacy.

Ditchman N, Sung C, Easton AB, Johnson KS, Batchos E.

NeuroRehabilitation. 2017;40(4):531-543. doi: 10.3233/NRE-171440.


Incidental context information increases recollection.

Ameen-Ali KE, Norman LJ, Eacott MJ, Easton A.

Learn Mem. 2017 Feb 15;24(3):136-139. doi: 10.1101/lm.042622.116. Print 2017 Mar.


Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.

Hill MD, Fang H, King HD, Iwuagwu CI, McDonald IM, Cook J, Zusi FC, Mate RA, Knox RJ, Post-Munson D, Easton A, Miller R, Lentz K, Clarke W, Benitex Y, Lodge N, Zaczek R, Denton R, Morgan D, Bristow L, Macor JE, Olson R.

ACS Med Chem Lett. 2016 Dec 1;8(1):133-137. doi: 10.1021/acsmedchemlett.6b00471. eCollection 2017 Jan 12.


GSK249320, A Monoclonal Antibody Against the Axon Outgrowth Inhibition Molecule Myelin-Associated Glycoprotein, Improves Outcome of Rodents with Experimental Stroke.

Cash D, Easton AC, Mesquita M, Beech J, Williams S, Lloyd A, Irving E, Cramer SC.

J Neurol Exp Neurosci. 2016;2(2):28-33. Epub 2016 Nov 21.


Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators.

Hill MD, Fang H, Brown JM, Molski T, Easton A, Han X, Miller R, Hill-Drzewi M, Gallagher L, Matchett M, Gulianello M, Balakrishnan A, Bertekap RL, Santone KS, Whiterock VJ, Zhuo X, Bronson JJ, Macor JE, Degnan AP.

ACS Med Chem Lett. 2016 Oct 3;7(12):1082-1086. eCollection 2016 Dec 8.


A SNP Based Linkage Map of the Arctic Charr (Salvelinus alpinus) Genome Provides Insights into the Diploidization Process After Whole Genome Duplication.

Nugent CM, Easton AA, Norman JD, Ferguson MM, Danzmann RG.

G3 (Bethesda). 2017 Feb 9;7(2):543-556. doi: 10.1534/g3.116.038026.


Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship.

Cook J, Zusi FC, McDonald IM, King D, Hill MD, Iwuagwu C, Mate RA, Fang H, Zhao R, Wang B, Cutrone J, Ma B, Gao Q, Knox RJ, Matchett M, Gallagher L, Ferrante M, Post-Munson D, Molski T, Easton A, Miller R, Jones K, Digavalli S, Healy F, Lentz K, Benitex Y, Clarke W, Natale J, Siuciak JA, Lodge N, Zaczek R, Denton R, Morgan D, Bristow LJ, Macor JE, Olson RE.

J Med Chem. 2016 Dec 22;59(24):11171-11181. doi: 10.1021/acs.jmedchem.6b01506. Epub 2016 Dec 13.


Triazolopyridine ethers as potent, orally active mGlu2 positive allosteric modulators for treating schizophrenia.

Higgins MA, Marcin LR, Christopher Zusi F, Gentles R, Ding M, Pearce BC, Easton A, Kostich WA, Seager MA, Bourin C, Bristow LJ, Johnson KA, Miller R, Hogan J, Whiterock V, Gulianello M, Ferrante M, Huang Y, Hendricson A, Alt A, Macor JE, Bronson JJ.

Bioorg Med Chem. 2017 Jan 15;25(2):496-513. doi: 10.1016/j.bmc.2016.11.018. Epub 2016 Nov 14.


Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential.

Degnan AP, Maxwell D, Balakrishnan A, Brown JM, Easton A, Gulianello M, Hanumegowda U, Hill-Drzewi M, Miller R, Santone KS, Senapati A, Shields EE, Sivarao DV, Westphal R, Whiterock VJ, Zhuo X, Bronson JJ, Macor JE.

Bioorg Med Chem Lett. 2016 Dec 15;26(24):5871-5876. doi: 10.1016/j.bmcl.2016.11.014. Epub 2016 Nov 9.


Human Brain Chemokine and Cytokine Expression in Sepsis: A Report of Three Cases.

Warford J, Lamport AC, Kennedy B, Easton AS.

Can J Neurol Sci. 2017 Jan;44(1):96-104. doi: 10.1017/cjn.2016.310. Epub 2016 Nov 11.


ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial.

Iro MA, Sadarangani M, Absoud M, Chong WK, Clark CA, Easton A, Gray V, Kneen R, Lim M, Pike M, Solomon T, Vincent A, Willis L, Yu LM, Pollard AJ.

BMJ Open. 2016 Nov 3;6(11):e012356. doi: 10.1136/bmjopen-2016-012356.


Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials.

Postler TS, Clawson AN, Amarasinghe GK, Basler CF, Bavari S, Benko M, Blasdell KR, Briese T, Buchmeier MJ, Bukreyev A, Calisher CH, Chandran K, Charrel R, Clegg CS, Collins PL, Juan Carlos T, Derisi JL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Emonet S, Formenty P, Fouchier RAM, Ghedin E, Gonzalez JP, Harrach B, Hewson R, Horie M, Jiang D, Kobinger G, Kondo H, Kropinski AM, Krupovic M, Kurath G, Lamb RA, Leroy EM, Lukashevich IS, Maisner A, Mushegian AR, Netesov SV, Nowotny N, Patterson JL, Payne SL, PaWeska JT, Peters CJ, Radoshitzky SR, Rima BK, Romanowski V, Rubbenstroth D, Sabanadzovic S, Sanfaçon H, Salvato MS, Schwemmle M, Smither SJ, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang LF, Varsani A, Whitfield AE, Zerbini FM, Kuhn JH.

Syst Biol. 2017 May 1;66(3):463-473. doi: 10.1093/sysbio/syw096.


Increased rates of sequelae post-encephalitis in individuals attending primary care practices in the United Kingdom: a population-based retrospective cohort study.

Granerod J, Davies NW, Ramanuj PP, Easton A, Brown DW, Thomas SL.

J Neurol. 2017 Feb;264(2):407-415. doi: 10.1007/s00415-016-8316-8. Epub 2016 Oct 20.


A Defective Interfering Influenza RNA Inhibits Infectious Influenza Virus Replication in Human Respiratory Tract Cells: A Potential New Human Antiviral.

Smith CM, Scott PD, O'Callaghan C, Easton AJ, Dimmock NJ.

Viruses. 2016 Aug 22;8(8). pii: E237. doi: 10.3390/v8080237.


Oxazolidinone-based allosteric modulators of mGluR5: Defining molecular switches to create a pharmacological tool box.

Huang H, Degnan AP, Balakrishnan A, Easton A, Gulianello M, Huang Y, Matchett M, Mattson G, Miller R, Santone KS, Senapati A, Shields EE, Sivarao DV, Snyder LB, Westphal R, Whiterock VJ, Yang F, Bronson JJ, Macor JE.

Bioorg Med Chem Lett. 2016 Sep 1;26(17):4165-9. doi: 10.1016/j.bmcl.2016.07.065. Epub 2016 Jul 28.


The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia.

Bristow LJ, Easton AE, Li YW, Sivarao DV, Lidge R, Jones KM, Post-Munson D, Daly C, Lodge NJ, Gallagher L, Molski T, Pieschl R, Chen P, Hendricson A, Westphal R, Cook J, Iwuagwu C, Morgan D, Benitex Y, King D, Macor JE, Zaczek R, Olson R.

PLoS One. 2016 Jul 28;11(7):e0159996. doi: 10.1371/journal.pone.0159996. eCollection 2016.


Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain.

Kostich W, Hamman BD, Li YW, Naidu S, Dandapani K, Feng J, Easton A, Bourin C, Baker K, Allen J, Savelieva K, Louis JV, Dokania M, Elavazhagan S, Vattikundala P, Sharma V, Das ML, Shankar G, Kumar A, Holenarsipur VK, Gulianello M, Molski T, Brown JM, Lewis M, Huang Y, Lu Y, Pieschl R, O'Malley K, Lippy J, Nouraldeen A, Lanthorn TH, Ye G, Wilson A, Balakrishnan A, Denton R, Grace JE, Lentz KA, Santone KS, Bi Y, Main A, Swaffield J, Carson K, Mandlekar S, Vikramadithyan RK, Nara SJ, Dzierba C, Bronson J, Macor JE, Zaczek R, Westphal R, Kiss L, Bristow L, Conway CM, Zambrowicz B, Albright CF.

J Pharmacol Exp Ther. 2016 Sep;358(3):371-86. doi: 10.1124/jpet.116.235333. Epub 2016 Jul 13.

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