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Items: 25


Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform.

Xu L, Durruthy-Durruthy R, Eastburn DJ, Pellegrino M, Shah O, Meyer E, Zehnder J.

Sci Rep. 2019 Jul 31;9(1):11119. doi: 10.1038/s41598-019-47297-z.


Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.

McMahon CM, Ferng T, Canaani J, Wang ES, Morrissette JJD, Eastburn DJ, Pellegrino M, Durruthy-Durruthy R, Watt CD, Asthana S, Lasater EA, DeFilippis R, Peretz CAC, McGary LHF, Deihimi S, Logan AC, Luger SM, Shah NP, Carroll M, Smith CC, Perl AE.

Cancer Discov. 2019 Aug;9(8):1050-1063. doi: 10.1158/2159-8290.CD-18-1453. Epub 2019 May 14.


High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics.

Pellegrino M, Sciambi A, Treusch S, Durruthy-Durruthy R, Gokhale K, Jacob J, Chen TX, Geis JA, Oldham W, Matthews J, Kantarjian H, Futreal PA, Patel K, Jones KW, Takahashi K, Eastburn DJ.

Genome Res. 2018 Sep;28(9):1345-1352. doi: 10.1101/gr.232272.117. Epub 2018 Aug 7.


A Global Meta-Analysis of Grazing Impacts on Soil Health Indicators.

Byrnes RC, Eastburn DJ, Tate KW, Roche LM.

J Environ Qual. 2018 Jul;47(4):758-765. doi: 10.2134/jeq2017.08.0313.


Seeding plants for long-term multiple ecosystem service goals.

Eastburn DJ, Roche LM, Doran MP, Blake PR, Bouril CS, Gamble G, Gornish ES.

J Environ Manage. 2018 Apr 1;211:191-197. doi: 10.1016/j.jenvman.2018.01.061. Epub 2018 Feb 4.


Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma.

Huang PY, Kandyba E, Jabouille A, Sjolund J, Kumar A, Halliwill K, McCreery M, DelRosario R, Kang HC, Wong CE, Seibler J, Beuger V, Pellegrino M, Sciambi A, Eastburn DJ, Balmain A.

Nat Genet. 2017 Nov;49(11):1624-1632. doi: 10.1038/ng.3957. Epub 2017 Sep 25.


Multiple ecosystem services in a working landscape.

Eastburn DJ, O'Geen AT, Tate KW, Roche LM.

PLoS One. 2017 Mar 16;12(3):e0166595. doi: 10.1371/journal.pone.0166595. eCollection 2017.


RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures.

Pellegrino M, Sciambi A, Yates JL, Mast JD, Silver C, Eastburn DJ.

BMC Genomics. 2016 May 17;17:361. doi: 10.1186/s12864-016-2694-2.


Microfluidic droplet enrichment for targeted sequencing.

Eastburn DJ, Huang Y, Pellegrino M, Sciambi A, Ptáček LJ, Abate AR.

Nucleic Acids Res. 2015 Jul 27;43(13):e86. doi: 10.1093/nar/gkv297. Epub 2015 Apr 14.


A molecular switch for the orientation of epithelial cell polarization.

Bryant DM, Roignot J, Datta A, Overeem AW, Kim M, Yu W, Peng X, Eastburn DJ, Ewald AJ, Werb Z, Mostov KE.

Dev Cell. 2014 Oct 27;31(2):171-87. doi: 10.1016/j.devcel.2014.08.027. Epub 2014 Oct 9.


Identification and genetic analysis of cancer cells with PCR-activated cell sorting.

Eastburn DJ, Sciambi A, Abate AR.

Nucleic Acids Res. 2014;42(16):e128. doi: 10.1093/nar/gku606. Epub 2014 Jul 16.


Ultrahigh-throughput Mammalian single-cell reverse-transcriptase polymerase chain reaction in microfluidic drops.

Eastburn DJ, Sciambi A, Abate AR.

Anal Chem. 2013 Aug 20;85(16):8016-21. doi: 10.1021/ac402057q. Epub 2013 Aug 8.


Picoinjection enables digital detection of RNA with droplet rt-PCR.

Eastburn DJ, Sciambi A, Abate AR.

PLoS One. 2013 Apr 26;8(4):e62961. doi: 10.1371/journal.pone.0062961. Print 2013.


Electrode-free picoinjection of microfluidic drops.

O'Donovan B, Eastburn DJ, Abate AR.

Lab Chip. 2012 Oct 21;12(20):4029-32.


Scrib regulates HGF-mediated epithelial morphogenesis and is stabilized by Sgt1-HSP90.

Eastburn DJ, Zegers MM, Mostov KE.

J Cell Sci. 2012 Sep 1;125(Pt 17):4147-57. doi: 10.1242/jcs.108670. Epub 2012 May 23.


Cattle grazing and conservation of a meadow-dependent amphibian species in the Sierra Nevada.

Roche LM, Latimer AM, Eastburn DJ, Tate KW.

PLoS One. 2012;7(4):e35734. doi: 10.1371/journal.pone.0035734. Epub 2012 Apr 25.


Phosphoinositides in cell architecture.

Shewan A, Eastburn DJ, Mostov K.

Cold Spring Harb Perspect Biol. 2011 Aug 1;3(8):a004796. doi: 10.1101/cshperspect.a004796. Review.


p120 catenin is required for normal renal tubulogenesis and glomerulogenesis.

Marciano DK, Brakeman PR, Lee CZ, Spivak N, Eastburn DJ, Bryant DM, Beaudoin GM 3rd, Hofmann I, Mostov KE, Reichardt LF.

Development. 2011 May;138(10):2099-109. doi: 10.1242/dev.056564. Erratum in: Development. 2011 Jun;138(12):2632.


A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor.

Su T, Bryant DM, Luton F, Vergés M, Ulrich SM, Hansen KC, Datta A, Eastburn DJ, Burlingame AL, Shokat KM, Mostov KE.

Nat Cell Biol. 2010 Dec;12(12):1143-53. doi: 10.1038/ncb2118. Epub 2010 Oct 31.


The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis.

Rodriguez-Fraticelli AE, Vergarajauregui S, Eastburn DJ, Datta A, Alonso MA, Mostov K, Martín-Belmonte F.

J Cell Biol. 2010 May 17;189(4):725-38. doi: 10.1083/jcb.201002047.


Laying the foundation for epithelia: insights into polarized basement membrane deposition.

Eastburn DJ, Mostov KE.

EMBO Rep. 2010 May;11(5):329-30. doi: 10.1038/embor.2010.54. Epub 2010 Apr 9. No abstract available.


Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity.

Yu W, Shewan AM, Brakeman P, Eastburn DJ, Datta A, Bryant DM, Fan QW, Weiss WA, Zegers MM, Mostov KE.

EMBO Rep. 2008 Sep;9(9):923-9. doi: 10.1038/embor.2008.135. Epub 2008 Jul 25.


Differential expression of members of the annexin multigene family in Arabidopsis.

Clark GB, Sessions A, Eastburn DJ, Roux SJ.

Plant Physiol. 2001 Jul;126(3):1072-84.

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