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Items: 12

1.

Identification of small molecule inhibitors of the hepatitis C virus RNA-dependent RNA polymerase from a pyrrolidine combinatorial mixture.

Burton G, Ku TW, Carr TJ, Kiesow T, Sarisky RT, Lin-Goerke J, Baker A, Earnshaw DL, Hofmann GA, Keenan RM, Dhanak D.

Bioorg Med Chem Lett. 2005 Mar 15;15(6):1553-6.

PMID:
15745795
2.

Enzymatic activities of the GB virus-B RNA-dependent RNA polymerase.

Ranjith-Kumar CT, Santos JL, Gutshall LL, Johnston VK, Lin-Goerke J, Kim MJ, Porter DJ, Maley D, Greenwood C, Earnshaw DL, Baker A, Gu B, Silverman C, Sarisky RT, Kao C.

Virology. 2003 Aug 1;312(2):270-80.

3.

Identification and biological characterization of heterocyclic inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.

Dhanak D, Duffy KJ, Johnston VK, Lin-Goerke J, Darcy M, Shaw AN, Gu B, Silverman C, Gates AT, Nonnemacher MR, Earnshaw DL, Casper DJ, Kaura A, Baker A, Greenwood C, Gutshall LL, Maley D, DelVecchio A, Macarron R, Hofmann GA, Alnoah Z, Cheng HY, Chan G, Khandekar S, Keenan RM, Sarisky RT.

J Biol Chem. 2002 Oct 11;277(41):38322-7. Epub 2002 Aug 6.

4.

Real experiences of uHTS: a prototypic 1536-well fluorescence anisotropy-based uHTS screen and application of well-level quality control procedures.

Turconi S, Shea K, Ashman S, Fantom K, Earnshaw DL, Bingham RP, Haupts UM, Brown MJ, Pope AJ.

J Biomol Screen. 2001 Oct;6(5):275-90.

PMID:
11689128
6.

Time-Resolved Fluorescence Energy Transfer DNA Helicase Assays for High Throughput Screening.

Earnshaw DL, Moore KJ, Greenwood CJ, Djaballah H, Jurewicz AJ, Murray KJ, Pope AJ.

J Biomol Screen. 1999;4(5):239-248.

PMID:
10838444
7.

CD23 (FcepsilonRII) release from cell membranes is mediated by a membrane-bound metalloprotease.

Marolewski AE, Buckle DR, Christie G, Earnshaw DL, Flamberg PL, Marshall LA, Smith DG, Mayer RJ.

Biochem J. 1998 Aug 1;333 ( Pt 3):573-9.

10.

Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus.

Earnshaw DL, Bacon TH, Darlison SJ, Edmonds K, Perkins RM, Vere Hodge RA.

Antimicrob Agents Chemother. 1992 Dec;36(12):2747-57.

12.

Unusual RNA polymerase content of Trypanosoma brucei nuclei.

Earnshaw DL, Beebee TJ, Gutteridge WE.

Biochem Biophys Res Commun. 1985 Sep 16;131(2):844-8.

PMID:
2413850

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