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Items: 21


Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model.

Tomic MT, Espinoza Y, Martinez Z, Pham K, Cobb RR, Snow DM, Earnhart CG, Pals T, Syar ES, Niemuth N, Kobs DJ, Farr-Jones S, Marks JD.

Toxins (Basel). 2019 Apr 6;11(4). pii: E208. doi: 10.3390/toxins11040208.


Analysis of the antigenic determinants of the OspC protein of the Lyme disease spirochetes: Evidence that the C10 motif is not immunodominant or required to elicit bactericidal antibody responses.

Izac JR, Camire AC, Earnhart CG, Embers ME, Funk RA, Breitschwerdt EB, Marconi RT.

Vaccine. 2019 Apr 17;37(17):2401-2407. doi: 10.1016/j.vaccine.2019.02.007. Epub 2019 Mar 25.


Identification of a defined linear epitope in the OspA protein of the Lyme disease spirochetes that elicits bactericidal antibody responses: Implications for vaccine development.

Izac JR, Oliver LD Jr, Earnhart CG, Marconi RT.

Vaccine. 2017 May 31;35(24):3178-3185. doi: 10.1016/j.vaccine.2017.04.079. Epub 2017 May 4.


Antibody profiling of canine IgG responses to the OspC protein of the Lyme disease spirochetes supports a multivalent approach in vaccine and diagnostic assay development.

Oliver LD Jr, Earnhart CG, Virginia-Rhodes D, Theisen M, Marconi RT.

Vet J. 2016 Dec;218:27-33. doi: 10.1016/j.tvjl.2016.11.001. Epub 2016 Nov 9.


The Borrelia hermsii factor H binding protein FhbA is not required for infectivity in mice or for resistance to human complement in vitro.

Fine LM, Miller DP, Mallory KL, Tegels BK, Earnhart CG, Marconi RT.

Infect Immun. 2014 Aug;82(8):3324-32. doi: 10.1128/IAI.01892-14. Epub 2014 May 27.


Assessment of the potential contribution of the highly conserved C-terminal motif (C10) of Borrelia burgdorferi outer surface protein C in transmission and infectivity.

Earnhart CG, Rhodes DV, Smith AA, Yang X, Tegels B, Carlyon JA, Pal U, Marconi RT.

Pathog Dis. 2014 Mar;70(2):176-84. doi: 10.1111/2049-632X.12119. Epub 2014 Feb 3.


Identification of Borrelia burgdorferi ospC genotypes in canine tissue following tick infestation: implications for Lyme disease vaccine and diagnostic assay design.

Rhodes DV, Earnhart CG, Mather TN, Meeus PF, Marconi RT.

Vet J. 2013 Nov;198(2):412-8. doi: 10.1016/j.tvjl.2013.07.019. Epub 2013 Aug 17.


Disulfide-mediated oligomer formation in Borrelia burgdorferi outer surface protein C, a critical virulence factor and potential Lyme disease vaccine candidate.

Earnhart CG, Rhodes DV, Marconi RT.

Clin Vaccine Immunol. 2011 Jun;18(6):901-6. doi: 10.1128/CVI.05004-11. Epub 2011 Apr 27.


Identification of residues within ligand-binding domain 1 (LBD1) of the Borrelia burgdorferi OspC protein required for function in the mammalian environment.

Earnhart CG, Leblanc DV, Alix KE, Desrosiers DC, Radolf JD, Marconi RT.

Mol Microbiol. 2010 Apr;76(2):393-408. doi: 10.1111/j.1365-2958.2010.07103.x. Epub 2010 Feb 28.


An octavalent lyme disease vaccine induces antibodies that recognize all incorporated OspC type-specific sequences.

Earnhart CG, Marconi RT.

Hum Vaccin. 2007 Nov-Dec;3(6):281-9. Epub 2007 Jul 2.


OspC phylogenetic analyses support the feasibility of a broadly protective polyvalent chimeric Lyme disease vaccine.

Earnhart CG, Marconi RT.

Clin Vaccine Immunol. 2007 May;14(5):628-34. Epub 2007 Mar 14.


Monoclonal antibody analysis of Perkinsus marinus extracellular products.

Earnhart CG, Gauthier DT, Vogelbein WK, Kaattari SL.

Int J Parasitol. 2005 Feb;35(2):171-84. Epub 2004 Dec 19.


Supplementation of Perkinsus marinus cultures with host plasma or tissue homogenate enhances their infectivity.

Earnhart CG, Vogelbein MA, Brown GD, Reece KS, Kaattari SL.

Appl Environ Microbiol. 2004 Jan;70(1):421-31.


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