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Items: 19


Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.

Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, DeTitta G, Luft JR, Lauricella A, Gulde S, Anderson LA, Kalyuzhniy O, Neely HM, Ross J, Earnest TN, Soltis M, Schoenfeld L, Zucker F, Merritt EA, Fan E, Verlinde CL, Hol WG.

J Med Chem. 2006 Oct 5;49(20):5939-46.


Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.

Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt 5):427-31. Epub 2006 Apr 12.


Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.

Holmes MA, Buckner FS, Van Voorhis WC, Mehlin C, Boni E, Earnest TN, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Hol WG, Merritt EA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Mar 1;62(Pt 3):180-5. Epub 2006 Feb 24.


Suite of three protein crystallography beamlines with single superconducting bend magnet as the source.

MacDowell AA, Celestre RS, Howells M, McKinney W, Krupnick J, Cambie D, Domning EE, Duarte RM, Kelez N, Plate DW, Cork CW, Earnest TN, Dickert J, Meigs G, Ralston C, Holton JM, Alber T, Berger JM, Agard DA, Padmore HA.

J Synchrotron Radiat. 2004 Nov 1;11(Pt 6):447-55. Epub 2004 Oct 22.


Structural genomics and structural biology: compare and contrast.

Chandonia JM, Earnest TN, Brenner SE.

Genome Biol. 2004;5(9):343. Epub 2004 Aug 25. No abstract available.


Structure of the ribosome at 5.5 A resolution and its interactions with functional ligands.

Noller HF, Yusupov MM, Yusupova GZ, Baucom A, Lieberman K, Lancaster L, Dallas A, Fredrick K, Earnest TN, Cate JH.

Cold Spring Harb Symp Quant Biol. 2001;66:57-66. Review. No abstract available.


Precursor Structure of Cephalosporin Acylase: Insights into Auto-Proteolytic Activation in a New N-Terminal Hydrolase Family.

Kim Y, Kim S, Earnest TN, Hol WGJ.

ScientificWorldJournal. 2002 May 22;2:115-116. doi: 10.1100/tsw.2002.54. eCollection 2002. No abstract available.


Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase family.

Kim Y, Kim S, Earnest TN, Hol WG.

J Biol Chem. 2002 Jan 25;277(4):2823-9. Epub 2001 Nov 8.


Crystal structure of the ribosome at 5.5 A resolution.

Yusupov MM, Yusupova GZ, Baucom A, Lieberman K, Earnest TN, Cate JH, Noller HF.

Science. 2001 May 4;292(5518):883-96. Epub 2001 Mar 29.


Single-wavelength anomalous diffraction phasing revisited.

Rice LM, Earnest TN, Brunger AT.

Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1413-20.


Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP.

Bard J, Zhelkovsky AM, Helmling S, Earnest TN, Moore CL, Bohm A.

Science. 2000 Aug 25;289(5483):1346-9.


X-ray crystal structures of 70S ribosome functional complexes.

Cate JH, Yusupov MM, Yusupova GZ, Earnest TN, Noller HF.

Science. 1999 Sep 24;285(5436):2095-104.


Clathrin self-assembly is mediated by a tandemly repeated superhelix.

Ybe JA, Brodsky FM, Hofmann K, Lin K, Liu SH, Chen L, Earnest TN, Fletterick RJ, Hwang PK.

Nature. 1999 May 27;399(6734):371-5.


A biophysical study of integral membrane protein folding.

Hunt JF, Earnest TN, Bousché O, Kalghatgi K, Reilly K, Horváth C, Rothschild KJ, Engelman DM.

Biochemistry. 1997 Dec 9;36(49):15156-76.


X-ray diffraction by crystals of beef heart ubiquinol: cytochrome c oxidoreductase.

Berry EA, Huang LS, Earnest TN, Jap BK.

J Mol Biol. 1992 Apr 20;224(4):1161-6.


Orientation of the bacteriorhodopsin chromophore probed by polarized Fourier transform infrared difference spectroscopy.

Earnest TN, Roepe P, Braiman MS, Gillespie J, Rothschild KJ.

Biochemistry. 1986 Dec 2;25(24):7793-8.


Evidence for a tyrosine protonation change during the primary phototransition of bacteriorhodopsin at low temperature.

Rothschild KJ, Roepe P, Ahl PL, Earnest TN, Bogomolni RA, Das Gupta SK, Mulliken CM, Herzfeld J.

Proc Natl Acad Sci U S A. 1986 Jan;83(2):347-51.


The site of attachment of retinal in bacteriorhodopsin. A resonance Raman study.

Rothschild KJ, Argade PV, Earnest TN, Huang KS, London E, Liao MJ, Bayley H, Khorana HG, Herzfeld J.

J Biol Chem. 1982 Aug 10;257(15):8592-5.

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