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Items: 20

1.

Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics.

LeDuc RD, Fellers RT, Early BP, Greer JB, Shams DP, Thomas PM, Kelleher NL.

Mol Cell Proteomics. 2019 Apr;18(4):796-805. doi: 10.1074/mcp.RA118.000993. Epub 2019 Jan 15.

PMID:
30647073
2.

Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry.

Haverland NA, Skinner OS, Fellers RT, Tariq AA, Early BP, LeDuc RD, Fornelli L, Compton PD, Kelleher NL.

J Am Soc Mass Spectrom. 2017 Jun;28(6):1203-1215. doi: 10.1007/s13361-017-1635-x. Epub 2017 Apr 3.

3.

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer.

Fornelli L, Durbin KR, Fellers RT, Early BP, Greer JB, LeDuc RD, Compton PD, Kelleher NL.

J Proteome Res. 2017 Feb 3;16(2):609-618. doi: 10.1021/acs.jproteome.6b00698. Epub 2016 Dec 2.

4.

He Died in the Snow.

Early BP.

J Soc Work End Life Palliat Care. 2016 Jan-Jun;12(1-2):17-9. doi: 10.1080/15524256.2016.1156606. No abstract available.

PMID:
27143570
5.

An informatic framework for decoding protein complexes by top-down mass spectrometry.

Skinner OS, Havugimana PC, Haverland NA, Fornelli L, Early BP, Greer JB, Fellers RT, Durbin KR, Do Vale LH, Melani RD, Seckler HS, Nelp MT, Belov ME, Horning SR, Makarov AA, LeDuc RD, Bandarian V, Compton PD, Kelleher NL.

Nat Methods. 2016 Mar;13(3):237-40. doi: 10.1038/nmeth.3731. Epub 2016 Jan 18.

6.

Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts.

Ntai I, LeDuc RD, Fellers RT, Erdmann-Gilmore P, Davies SR, Rumsey J, Early BP, Thomas PM, Li S, Compton PD, Ellis MJ, Ruggles KV, Fenyö D, Boja ES, Rodriguez H, Townsend RR, Kelleher NL.

Mol Cell Proteomics. 2016 Jan;15(1):45-56. doi: 10.1074/mcp.M114.047480. Epub 2015 Oct 26.

7.

ProSight Lite: graphical software to analyze top-down mass spectrometry data.

Fellers RT, Greer JB, Early BP, Yu X, LeDuc RD, Kelleher NL, Thomas PM.

Proteomics. 2015 Apr;15(7):1235-8. doi: 10.1002/pmic.201570050.

8.

The C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics.

LeDuc RD, Fellers RT, Early BP, Greer JB, Thomas PM, Kelleher NL.

J Proteome Res. 2014 Jul 3;13(7):3231-40. doi: 10.1021/pr401277r. Epub 2014 Jun 12.

9.

Applying label-free quantitation to top down proteomics.

Ntai I, Kim K, Fellers RT, Skinner OS, Smith AD 4th, Early BP, Savaryn JP, LeDuc RD, Thomas PM, Kelleher NL.

Anal Chem. 2014 May 20;86(10):4961-8. doi: 10.1021/ac500395k. Epub 2014 May 7.

10.

Fragmentation of integral membrane proteins in the gas phase.

Skinner OS, Catherman AD, Early BP, Thomas PM, Compton PD, Kelleher NL.

Anal Chem. 2014 May 6;86(9):4627-34. doi: 10.1021/ac500864w. Epub 2014 Apr 17.

11.

The first pilot project of the consortium for top-down proteomics: a status report.

Dang X, Scotcher J, Wu S, Chu RK, Tolić N, Ntai I, Thomas PM, Fellers RT, Early BP, Zheng Y, Durbin KR, Leduc RD, Wolff JJ, Thompson CJ, Pan J, Han J, Shaw JB, Salisbury JP, Easterling M, Borchers CH, Brodbelt JS, Agar JN, Paša-Tolić L, Kelleher NL, Young NL.

Proteomics. 2014 May;14(10):1130-40. doi: 10.1002/pmic.201300438. Epub 2014 Apr 14.

12.

Ultraviolet photodissociation for characterization of whole proteins on a chromatographic time scale.

Cannon JR, Cammarata MB, Robotham SA, Cotham VC, Shaw JB, Fellers RT, Early BP, Thomas PM, Kelleher NL, Brodbelt JS.

Anal Chem. 2014 Feb 18;86(4):2185-92. doi: 10.1021/ac403859a. Epub 2014 Jan 29.

13.

Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.

Catherman AD, Durbin KR, Ahlf DR, Early BP, Fellers RT, Tran JC, Thomas PM, Kelleher NL.

Mol Cell Proteomics. 2013 Dec;12(12):3465-73. doi: 10.1074/mcp.M113.030114. Epub 2013 Sep 10.

14.

Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation.

Shaw JB, Li W, Holden DD, Zhang Y, Griep-Raming J, Fellers RT, Early BP, Thomas PM, Kelleher NL, Brodbelt JS.

J Am Chem Soc. 2013 Aug 28;135(34):12646-51. doi: 10.1021/ja4029654. Epub 2013 Jun 4.

15.

Top down proteomics of human membrane proteins from enriched mitochondrial fractions.

Catherman AD, Li M, Tran JC, Durbin KR, Compton PD, Early BP, Thomas PM, Kelleher NL.

Anal Chem. 2013 Feb 5;85(3):1880-8. doi: 10.1021/ac3031527. Epub 2013 Jan 23.

16.

Evaluation of the compact high-field orbitrap for top-down proteomics of human cells.

Ahlf DR, Compton PD, Tran JC, Early BP, Thomas PM, Kelleher NL.

J Proteome Res. 2012 Aug 3;11(8):4308-14. doi: 10.1021/pr3004216. Epub 2012 Jul 13.

17.

A protease for 'middle-down' proteomics.

Wu C, Tran JC, Zamdborg L, Durbin KR, Li M, Ahlf DR, Early BP, Thomas PM, Sweedler JV, Kelleher NL.

Nat Methods. 2012 Jun 17;9(8):822-4. doi: 10.1038/nmeth.2074.

18.

Mapping intact protein isoforms in discovery mode using top-down proteomics.

Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, Compton PD, Thomas PM, Kelleher NL.

Nature. 2011 Oct 30;480(7376):254-8. doi: 10.1038/nature10575.

19.

ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry.

Zamdborg L, LeDuc RD, Glowacz KJ, Kim YB, Viswanathan V, Spaulding IT, Early BP, Bluhm EJ, Babai S, Kelleher NL.

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W701-6. Epub 2007 Jun 22.

20.

The needs and supportive networks of the dying: an assessment instrument and mapping procedure for hospice patients.

Early BP, Smith ED, Todd L, Beem T.

Am J Hosp Palliat Care. 2000 Mar-Apr;17(2):87-96.

PMID:
11406963

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