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Items: 1 to 50 of 80

1.

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke.

Pires PW, Earley S.

Elife. 2018 Sep 21;7. pii: e35316. doi: 10.7554/eLife.35316.

2.

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy.

Pritchard HAT, Pires PW, Yamasaki E, Thakore P, Earley S.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9745-E9752. doi: 10.1073/pnas.1804593115. Epub 2018 Sep 4.

3.

SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract.

Zheng H, Drumm BT, Earley S, Sung TS, Koh SD, Sanders KM.

Sci Signal. 2018 Jun 12;11(534). pii: eaaq0918. doi: 10.1126/scisignal.aaq0918.

PMID:
29895614
4.

Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system.

Peng H, Jensen DD, Li W, Sullivan MN, Buller SA, Worker CJ, Cooper SG, Zheng S, Earley S, Sigmund CD, Feng Y.

Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H580-H592. doi: 10.1152/ajpheart.00310.2017. Epub 2017 Dec 15.

PMID:
29350998
5.

Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility.

Pritchard HAT, Gonzales AL, Pires PW, Drumm BT, Ko EA, Sanders KM, Hennig GW, Earley S.

Sci Signal. 2017 Sep 19;10(497). pii: eaan2694. doi: 10.1126/scisignal.aan2694.

PMID:
28928237
6.

Pyrin-only protein 2 limits inflammation but improves protection against bacteria.

Periasamy S, Porter KA, Atianand MK, T Le H, Earley S, Duffy EB, Haller MC, Chin H, Harton JA.

Nat Commun. 2017 Jun 5;8:15564. doi: 10.1038/ncomms15564.

7.

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells.

Pires PW, Ko EA, Pritchard HAT, Rudokas M, Yamasaki E, Earley S.

J Physiol. 2017 Jul 15;595(14):4735-4753. doi: 10.1113/JP274310. Epub 2017 Jun 1.

8.

Development and validation of a quantitative confirmatory method for 30 β-lactam antibiotics in bovine muscle using liquid chromatography coupled to tandem mass spectrometry.

Di Rocco M, Moloney M, O'Beirne T, Earley S, Berendsen B, Furey A, Danaher M.

J Chromatogr A. 2017 Jun 2;1500:121-135. doi: 10.1016/j.chroma.2017.04.022. Epub 2017 Apr 12.

PMID:
28449875
9.

Redox regulation of transient receptor potential channels in the endothelium.

Pires PW, Earley S.

Microcirculation. 2017 Apr;24(3). doi: 10.1111/micc.12329. Review.

10.

Isolation and Cannulation of Cerebral Parenchymal Arterioles.

Pires PW, Dabertrand F, Earley S.

J Vis Exp. 2016 May 23;(111). doi: 10.3791/53835.

11.

No Static at All: Tuning Into the Complexities of Ca2+ Signaling in the Endothelium.

Pires PW, Earley S.

Circ Res. 2016 Apr 1;118(7):1042-4. doi: 10.1161/CIRCRESAHA.116.308519. No abstract available.

12.

A TRPC3 signalling complex promotes cerebral artery remodelling during hypertension.

Pires PW, Earley S.

Cardiovasc Res. 2016 Jan 1;109(1):4-5. doi: 10.1093/cvr/cvv261. Epub 2015 Nov 27. No abstract available.

PMID:
26614778
13.

Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.

Pires PW, Sullivan MN, Pritchard HA, Robinson JJ, Earley S.

Am J Physiol Heart Circ Physiol. 2015 Dec 15;309(12):H2031-41. doi: 10.1152/ajpheart.00140.2015. Epub 2015 Oct 9.

14.

Transient receptor potential channels in the vasculature.

Earley S, Brayden JE.

Physiol Rev. 2015 Apr;95(2):645-90. doi: 10.1152/physrev.00026.2014. Review.

15.

Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.

Sullivan MN, Gonzales AL, Pires PW, Bruhl A, Leo MD, Li W, Oulidi A, Boop FA, Feng Y, Jaggar JH, Welsh DG, Earley S.

Sci Signal. 2015 Jan 6;8(358):ra2. doi: 10.1126/scisignal.2005659.

16.

Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes.

Streifel KM, Gonzales AL, De Miranda B, Mouneimne R, Earley S, Tjalkens R.

PLoS One. 2014 Nov 3;9(11):e110996. doi: 10.1371/journal.pone.0110996. eCollection 2014.

17.

TRPs in the kidney - location, location, location.

Pires PW, Earley S.

Acta Physiol (Oxf). 2015 Feb;213(2):296-7. doi: 10.1111/apha.12396. Epub 2014 Oct 18. No abstract available.

18.

Ca(V)3.2 channels and the induction of negative feedback in cerebral arteries.

Harraz OF, Abd El-Rahman RR, Bigdely-Shamloo K, Wilson SM, Brett SE, Romero M, Gonzales AL, Earley S, Vigmond EJ, Nygren A, Menon BK, Mufti RE, Watson T, Starreveld Y, Furstenhaupt T, Muellerleile PR, Kurjiaka DT, Kyle BD, Braun AP, Welsh DG.

Circ Res. 2014 Sep 12;115(7):650-61. doi: 10.1161/CIRCRESAHA.114.304056. Epub 2014 Aug 1.

19.

A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

Gonzales AL, Yang Y, Sullivan MN, Sanders L, Dabertrand F, Hill-Eubanks DC, Nelson MT, Earley S.

Sci Signal. 2014 May 27;7(327):ra49. doi: 10.1126/scisignal.2004732.

20.

Calcineurin/nuclear factor of activated T cells-coupled vanilliod transient receptor potential channel 4 ca2+ sparklets stimulate airway smooth muscle cell proliferation.

Zhao L, Sullivan MN, Chase M, Gonzales AL, Earley S.

Am J Respir Cell Mol Biol. 2014 Jun;50(6):1064-75. doi: 10.1165/rcmb.2013-0416OC.

21.

Neuron-specific (pro)renin receptor knockout prevents the development of salt-sensitive hypertension.

Li W, Peng H, Mehaffey EP, Kimball CD, Grobe JL, van Gool JM, Sullivan MN, Earley S, Danser AH, Ichihara A, Feng Y.

Hypertension. 2014 Feb;63(2):316-23. doi: 10.1161/HYPERTENSIONAHA.113.02041. Epub 2013 Nov 18.

22.

Control of urinary bladder smooth muscle excitability by the TRPM4 channel modulator 9-phenanthrol.

Parajuli SP, Hristov KL, Sullivan MN, Xin W, Smith AC, Earley S, Malysz J, Petkov GV.

Channels (Austin). 2013 Nov-Dec;7(6):537-40. doi: 10.4161/chan.26289. Epub 2013 Sep 13.

23.

TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization.

Sullivan MN, Earley S.

Am J Physiol Cell Physiol. 2013 Nov 15;305(10):C999-C1008. doi: 10.1152/ajpcell.00273.2013. Epub 2013 Sep 11. Review.

25.

Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection.

Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R.

Neoplasia. 2013 Jul;15(7):684-93.

26.

Endothelial control of vasodilation: integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids.

Ellinsworth DC, Earley S, Murphy TV, Sandow SL.

Pflugers Arch. 2014 Mar;466(3):389-405. doi: 10.1007/s00424-013-1303-3. Epub 2013 Jun 8. Review.

27.

TRPM4 channels in smooth muscle function.

Earley S.

Pflugers Arch. 2013 Sep;465(9):1223-31. doi: 10.1007/s00424-013-1250-z. Epub 2013 Feb 27. Review.

28.

Smooth muscle cell Ca²⁺: think locally, act globally.

Earley S.

Microcirculation. 2013 May;20(4):279-80. doi: 10.1111/micc.12049.

29.

Robust internal elastic lamina fenestration in skeletal muscle arteries.

Kirby BS, Bruhl A, Sullivan MN, Francis M, Dinenno FA, Earley S.

PLoS One. 2013;8(1):e54849. doi: 10.1371/journal.pone.0054849. Epub 2013 Jan 24.

30.

Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology.

Smith AC, Hristov KL, Cheng Q, Xin W, Parajuli SP, Earley S, Malysz J, Petkov GV.

Am J Physiol Cell Physiol. 2013 Mar 1;304(5):C467-77. doi: 10.1152/ajpcell.00169.2012. Epub 2013 Jan 9.

31.

TRPM4 channel: a new player in urinary bladder smooth muscle function in rats.

Smith AC, Parajuli SP, Hristov KL, Cheng Q, Soder RP, Afeli SA, Earley S, Xin W, Malysz J, Petkov GV.

Am J Physiol Renal Physiol. 2013 Apr 1;304(7):F918-29. doi: 10.1152/ajprenal.00417.2012. Epub 2013 Jan 2.

32.

Regulation of cerebral artery smooth muscle membrane potential by Ca²⁺-activated cation channels.

Gonzales AL, Earley S.

Microcirculation. 2013 May;20(4):337-47. doi: 10.1111/micc.12023. Review.

33.

Recruitment of dynamic endothelial Ca2+ signals by the TRPA1 channel activator AITC in rat cerebral arteries.

Qian X, Francis M, Solodushko V, Earley S, Taylor MS.

Microcirculation. 2013 Feb;20(2):138-48. doi: 10.1111/micc.12004.

34.

Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells.

Sullivan MN, Francis M, Pitts NL, Taylor MS, Earley S.

Mol Pharmacol. 2012 Sep;82(3):464-72. doi: 10.1124/mol.112.078584. Epub 2012 Jun 11.

35.

TRPA1 channels in the vasculature.

Earley S.

Br J Pharmacol. 2012 Sep;167(1):13-22. doi: 10.1111/j.1476-5381.2012.02018.x. Review.

36.

In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution.

Earley S, Vinegoni C, Dunham J, Gorbatov R, Feruglio PF, Weissleder R.

Cancer Res. 2012 Jun 15;72(12):2949-56. doi: 10.1158/0008-5472.CAN-11-4096. Epub 2012 Apr 13.

37.

Endogenous cytosolic Ca(2+) buffering is necessary for TRPM4 activity in cerebral artery smooth muscle cells.

Gonzales AL, Earley S.

Cell Calcium. 2012 Jan;51(1):82-93. doi: 10.1016/j.ceca.2011.11.004. Epub 2011 Dec 7.

38.

Basal protein kinase Cδ activity is required for membrane localization and activity of TRPM4 channels in cerebral artery smooth muscle cells.

Garcia ZI, Bruhl A, Gonzales AL, Earley S.

Channels (Austin). 2011 May-Jun;5(3):210-4. Epub 2011 May 1.

39.

Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method.

Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R.

Angew Chem Int Ed Engl. 2011 Feb 18;50(8):1922-5. doi: 10.1002/anie.201006579. Epub 2011 Jan 21. No abstract available.

40.

Functional Significance of Transient Receptor Potential Channels in Vascular Function.

Earley S, Reading S, Brayden JE.

In: Liedtke WB, Heller S, editors. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. Boca Raton (FL): CRC Press/Taylor & Francis; 2007. Chapter 26.

41.

Bioorthogonal small-molecule ligands for PARP1 imaging in living cells.

Reiner T, Earley S, Turetsky A, Weissleder R.

Chembiochem. 2010 Nov 22;11(17):2374-7. doi: 10.1002/cbic.201000477. No abstract available.

42.

(Sub)family feud: crosstalk between TRPC channels in vascular smooth muscle cells during vasoconstrictor agonist stimulation.

Earley S, Gonzales AL.

J Physiol. 2010 Oct 1;588(Pt 19):3637-8. doi: 10.1113/jphysiol.2010.197657. No abstract available.

43.

Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle.

Gonzales AL, Garcia ZI, Amberg GC, Earley S.

Am J Physiol Cell Physiol. 2010 Nov;299(5):C1195-202. doi: 10.1152/ajpcell.00269.2010. Epub 2010 Sep 8.

44.

Local regulation of arterial L-type calcium channels by reactive oxygen species.

Amberg GC, Earley S, Glapa SA.

Circ Res. 2010 Oct 15;107(8):1002-10. doi: 10.1161/CIRCRESAHA.110.217018. Epub 2010 Aug 26.

45.

Endothelium-dependent cerebral artery dilation mediated by transient receptor potential and Ca2+-activated K+ channels.

Earley S.

J Cardiovasc Pharmacol. 2011 Feb;57(2):148-53. doi: 10.1097/FJC.0b013e3181f580d9. Review.

PMID:
20729757
46.

Development and validation of a rapid multi-class method for the confirmation of fourteen prohibited medicinal additives in pig and poultry compound feed by liquid chromatography-tandem mass spectrometry.

Cronly M, Behan P, Foley B, Malone E, Earley S, Gallagher M, Shearan P, Regan L.

J Pharm Biomed Anal. 2010 Dec 1;53(4):929-38. doi: 10.1016/j.jpba.2010.06.027. Epub 2010 Jul 1.

PMID:
20643524
47.

Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells.

Crnich R, Amberg GC, Leo MD, Gonzales AL, Tamkun MM, Jaggar JH, Earley S.

Am J Physiol Cell Physiol. 2010 Sep;299(3):C682-94. doi: 10.1152/ajpcell.00101.2010. Epub 2010 Jul 7.

48.

Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle.

Earley S.

Microcirculation. 2010 May;17(4):237-49. doi: 10.1111/j.1549-8719.2010.00026.x. Review.

49.

Ca2+ release from the sarcoplasmic reticulum is required for sustained TRPM4 activity in cerebral artery smooth muscle cells.

Gonzales AL, Amberg GC, Earley S.

Am J Physiol Cell Physiol. 2010 Aug;299(2):C279-88. doi: 10.1152/ajpcell.00550.2009. Epub 2010 Apr 28.

50.

Transient receptor potential channels and vascular function.

Earley S, Brayden JE.

Clin Sci (Lond). 2010 Apr 7;119(1):19-36. doi: 10.1042/CS20090641. Review.

PMID:
20370719

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