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Items: 21

1.

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.

Sohal SS, Eapen MS, Naidu VGM, Sharma P.

ERJ Open Res. 2019 Feb 11;5(1). pii: 00159-2018. doi: 10.1183/23120541.00159-2018. eCollection 2019 Feb.

PMID:
30775377
2.

Impact of Maternal Air Pollution Exposure on Children's Lung Health: An Indian Perspective.

Saha P, Johny E, Dangi A, Shinde S, Brake S, Eapen MS, Sohal SS, Naidu V, Sharma P.

Toxics. 2018 Nov 16;6(4). pii: E68. doi: 10.3390/toxics6040068. Review.

3.

Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies.

Eapen MS, Sharma P, Thompson IE, Lu W, Myers S, Hansbro PM, Sohal SS.

Lab Invest. 2019 Feb;99(2):150-157. doi: 10.1038/s41374-018-0146-0. Epub 2018 Nov 19. Review.

PMID:
30451982
4.

Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.

Eapen MS, Hansbro PM, Larsson-Callerfelt AK, Jolly MK, Myers S, Sharma P, Jones B, Rahman MA, Markos J, Chia C, Larby J, Haug G, Hardikar A, Weber HC, Mabeza G, Cavalheri V, Khor YH, McDonald CF, Sohal SS.

Drugs. 2018 Nov;78(16):1717-1740. doi: 10.1007/s40265-018-1001-8. Review.

PMID:
30392114
5.

Dysfunctional Immunity and Microbial Adhesion Molecules in Smoking-induced Pneumonia.

Eapen MS, Sharma P, Moodley YP, Hansbro PM, Sohal SS.

Am J Respir Crit Care Med. 2019 Jan 15;199(2):250-251. doi: 10.1164/rccm.201808-1553LE. No abstract available.

PMID:
30290125
6.

Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease.

Eapen MS, Kota A, Vindin H, McAlinden KD, Xenaki D, Oliver BG, Deshpande DA, Sohal SS, Sharma P.

Clin Sci (Lond). 2018 Jul 31;132(14):1615-1627. doi: 10.1042/CS20180398. Print 2018 Jul 31.

7.

sE-cadherin and sVE-cadherin indicate active epithelial/endothelial to mesenchymal transition (EMT and EndoMT) in smokers and COPD: implications for new biomarkers and therapeutics.

Eapen MS, Myers S, Lu W, Tanghe C, Sharma P, Sohal SS.

Biomarkers. 2018 Nov;23(7):709-711. doi: 10.1080/1354750X.2018.1479772. Epub 2018 Jun 19. No abstract available.

PMID:
29781727
8.

Understanding novel mechanisms of microbial pathogenesis in chronic lung disease: implications for new therapeutic targets.

Eapen MS, Sohal SS.

Clin Sci (Lond). 2018 Feb 8;132(3):375-379. doi: 10.1042/CS20171261. Print 2018 Feb 14.

PMID:
29439118
9.

Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD).

Eapen MS, Hansbro PM, McAlinden K, Kim RY, Ward C, Hackett TL, Walters EH, Sohal SS.

Sci Rep. 2017 Oct 17;7(1):13392. doi: 10.1038/s41598-017-13888-x.

10.

Potential Mechanisms of Microbial Pathogens in Idiopathic Interstitial Lung Disease.

Sohal SS, Hansbro PM, Shukla SD, Eapen MS, Walters EH.

Chest. 2017 Oct;152(4):899-900. doi: 10.1016/j.chest.2017.05.024. No abstract available.

PMID:
28991543
11.

Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox.

Eapen MS, Myers S, Walters EH, Sohal SS.

Expert Rev Respir Med. 2017 Oct;11(10):827-839. doi: 10.1080/17476348.2017.1360769. Epub 2017 Aug 2. Review.

PMID:
28743228
12.

Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease.

Jolly MK, Ward C, Eapen MS, Myers S, Hallgren O, Levine H, Sohal SS.

Dev Dyn. 2018 Mar;247(3):346-358. doi: 10.1002/dvdy.24541. Epub 2017 Jul 21. Review.

PMID:
28646553
13.

Epithelial-Mesenchymal Transition: A Necessary New Therapeutic Target in Chronic Obstructive Pulmonary Disease?

Sohal SS, Eapen MS, Ward C, Walters EH.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):393-394. doi: 10.1164/rccm.201704-0771LE. No abstract available.

PMID:
28640653
14.

Airway inflammation and inhaled corticosteroids in COPD.

Sohal SS, Eapen MS, Ward C, Walters EH.

Eur Respir J. 2017 Jun 15;49(6). pii: 1700289. doi: 10.1183/13993003.00289-2017. Print 2017 Jun. No abstract available.

15.

Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide.

Chen L, Eapen MS, Zosky GR.

Sci Rep. 2017 Mar 27;7:45172. doi: 10.1038/srep45172.

16.

Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD.

Eapen MS, McAlinden K, Tan D, Weston S, Ward C, Muller HK, Walters EH, Sohal SS.

Respirology. 2017 Aug;22(6):1125-1132. doi: 10.1111/resp.13021. Epub 2017 Mar 22.

PMID:
28326668
17.

Ventilatory efficiency slope as a predictor of suitability for surgery in chronic obstructive pulmonary disease patients with lung cancer.

Eapen MS, Grover R, Ahuja K, Williams A, Sohal SS.

Ann Transl Med. 2016 Aug;4(15):296. doi: 10.21037/atm.2016.07.20. No abstract available.

18.

Platelet activating factor receptor: gateway for bacterial chronic airway infection in chronic obstructive pulmonary disease and potential therapeutic target.

Shukla SD, Sohal SS, O'Toole RF, Eapen MS, Walters EH.

Expert Rev Respir Med. 2015 Aug;9(4):473-85. doi: 10.1586/17476348.2015.1070673. Review.

PMID:
26207607
19.

Evaluation of nonradioactive cell-free cAMP assays for measuring in vitro phosphodiesterase activity.

Eapen MS, Sodhi R, Balakrishnan G, Dastidar S, Ray A, Vijayakrishnan L.

Pharmacology. 2010;85(5):280-5. doi: 10.1159/000290641. Epub 2010 Apr 24.

PMID:
20424496
20.

Purification of recombinant human phosphodiesterase 7A expressed in Dictyostelium discoideum.

Arya R, Gupta S, Aslam S, Kaur NJ, Seth A, Eapen MS, Malik R, Vijayakrishnan L, Saini KS.

Protein Expr Purif. 2008 Oct;61(2):149-54. doi: 10.1016/j.pep.2008.05.002. Epub 2008 May 14.

PMID:
18547817
21.

Small-molecule inhibitors of PDE-IV and -VII in the treatment of respiratory diseases and chronic inflammation.

Vijayakrishnan L, Rudra S, Eapen MS, Dastidar S, Ray A.

Expert Opin Investig Drugs. 2007 Oct;16(10):1585-99. Review.

PMID:
17922623

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