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Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients.

Tangedal S, Nielsen R, Aanerud M, Persson LJ, Wiker HG, Bakke PS, Hiemstra PS, Eagan TM.

PLoS One. 2019 Sep 17;14(9):e0222449. doi: 10.1371/journal.pone.0222449. eCollection 2019.


Laboratory contamination in airway microbiome studies.

Drengenes C, Wiker HG, Kalananthan T, Nordeide E, Eagan TML, Nielsen R.

BMC Microbiol. 2019 Aug 14;19(1):187. doi: 10.1186/s12866-019-1560-1.


Motivation and response rates in bronchoscopy studies.

Martinsen EMH, Eagan TML, Leiten EO, Nordeide E, Bakke PS, Lehmann S, Nielsen R.

Multidiscip Respir Med. 2019 May 2;14:14. doi: 10.1186/s40248-019-0178-3. eCollection 2019.


Guideline adherence in hospital recruited and population based COPD patients.

Jouleh B, Erdal M, Eagan TM, Bakke P, Gulsvik A, Nielsen R.

BMC Pulm Med. 2018 Dec 20;18(1):195. doi: 10.1186/s12890-018-0756-8.


Lung hyperinflation and functional exercise capacity in patients with COPD - a three-year longitudinal study.

Aalstad LT, Hardie JA, Espehaug B, Thorsen E, Bakke PS, Eagan TML, Frisk B.

BMC Pulm Med. 2018 Dec 6;18(1):187. doi: 10.1186/s12890-018-0747-9.


Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls.

van der Does AM, Heijink M, Mayboroda OA, Persson LJ, Aanerud M, Bakke P, Eagan TM, Hiemstra PS, Giera M.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Mar;1864(3):224-233. doi: 10.1016/j.bbalip.2018.11.012. Epub 2018 Dec 5.


Median regression spline modeling of longitudinal FEV1 measurements in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) patients.

Conrad DJ, Bailey BA, Hardie JA, Bakke PS, Eagan TML, Aarli BB.

PLoS One. 2017 Dec 20;12(12):e0190061. doi: 10.1371/journal.pone.0190061. eCollection 2017.


A pilot study of hot-wire, ultrasonic and wedge-bellows spirometer inter- and intra-variability.

Aardal ME, Svendsen LL, Lehmann S, Eagan TM, Haaland I.

BMC Res Notes. 2017 Oct 10;10(1):497. doi: 10.1186/s13104-017-2825-0.


Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients.

Tangedal S, Aanerud M, Grønseth R, Drengenes C, Wiker HG, Bakke PS, Eagan TM.

Respir Res. 2017 Aug 29;18(1):164. doi: 10.1186/s12931-017-0645-3.


The association of tidal EFL with exercise performance, exacerbations, and death in COPD.

Aarli BB, Calverley PM, Jensen RL, Dellacà R, Eagan TM, Bakke PS, Hardie JA.

Int J Chron Obstruct Pulmon Dis. 2017 Jul 26;12:2179-2188. doi: 10.2147/COPD.S138720. eCollection 2017.


Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease.

Persson LJ, Aanerud M, Hardie JA, Miodini Nilsen R, Bakke PS, Eagan TM, Hiemstra PS.

Eur Respir J. 2017 Mar 15;49(3). pii: 1601328. doi: 10.1183/13993003.01328-2016. Print 2017 Mar.


Growth differentiation factor-15 is a predictor of important disease outcomes in patients with COPD.

Husebø GR, Grønseth R, Lerner L, Gyuris J, Hardie JA, Bakke PS, Eagan TM.

Eur Respir J. 2017 Mar 15;49(3). pii: 1601298. doi: 10.1183/13993003.01298-2016. Print 2017 Mar.


Complications and discomfort of bronchoscopy: a systematic review.

Leiten EO, Martinsen EM, Bakke PS, Eagan TM, Grønseth R.

Eur Clin Respir J. 2016 Nov 11;3:33324. doi: 10.3402/ecrj.v3.33324. eCollection 2016. Review.


Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients.

Erdal M, Johannessen A, Eagan TM, Bakke P, Gulsvik A, Grønseth R.

Int J Chron Obstruct Pulmon Dis. 2016 Sep 2;11:2099-108. doi: 10.2147/COPD.S108720. eCollection 2016.


Change in pulmonary diffusion capacity in a general population sample over 9 years.

Storebø ML, Eagan TM, Eide GE, Gulsvik A, Thorsen E, Bakke PS.

Eur Clin Respir J. 2016 Sep 2;3:31265. doi: 10.3402/ecrj.v3.31265. eCollection 2016.


Self-reported influenza vaccination and protective serum antibody titers in a cohort of COPD patients.

Eagan TM, Hardie JA, Jul-Larsen Å, Grydeland TB, Bakke PS, Cox RJ.

Respir Med. 2016 Jun;115:53-9. doi: 10.1016/j.rmed.2016.04.008. Epub 2016 Apr 20.


Macrophage migration inhibitory factor, a role in COPD.

Husebø GR, Bakke PS, Grønseth R, Hardie JA, Ueland T, Aukrust P, Eagan TM.

Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1;311(1):L1-7. doi: 10.1152/ajplung.00461.2015. Epub 2016 May 17.


Associations between obstructive lung disease and symptoms of obstructive sleep apnoea in a general population.

Jonassen TM, Eagan TM, Bjorvatn B, Lehmann S.

Clin Respir J. 2018 Jan;12(1):31-39. doi: 10.1111/crj.12472. Epub 2016 Mar 31.


Participation in research bronchoscopy: a literature review.

Martinsen EM, Leiten EO, Bakke PS, Eagan TM, Grønseth R.

Eur Clin Respir J. 2016 Feb 3;3:29511. doi: 10.3402/ecrj.v3.29511. eCollection 2016. Review.


Peak oxygen uptake and breathing pattern in COPD patients--a four-year longitudinal study.

Frisk B, Hardie JA, Espehaug B, Strand LI, Moe-Nilssen R, Eagan TM, Bakke PS, Thorsen E.

BMC Pulm Med. 2015 Aug 19;15:93. doi: 10.1186/s12890-015-0095-y.


Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD.

Persson LJ, Aanerud M, Hiemstra PS, Michelsen AE, Ueland T, Hardie JA, Aukrust P, Bakke PS, Eagan TM.

PLoS One. 2015 Mar 24;10(3):e0121622. doi: 10.1371/journal.pone.0121622. eCollection 2015.


Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients.

Tangedal S, Aanerud M, Persson LJ, Brokstad KA, Bakke PS, Eagan TM.

Respir Res. 2014 Nov 15;15:138. doi: 10.1186/s12931-014-0138-6.


Variability of within-breath reactance in COPD patients and its association with dyspnoea.

Aarli BB, Calverley PM, Jensen RL, Eagan TM, Bakke PS, Hardie JA.

Eur Respir J. 2015 Mar;45(3):625-34. doi: 10.1183/09031936.00051214. Epub 2014 Oct 30. Erratum in: Eur Respir J. 2017 Jan 25;49(1):.


Predictors of exacerbations in chronic obstructive pulmonary disease--results from the Bergen COPD cohort study.

Husebø GR, Bakke PS, Aanerud M, Hardie JA, Ueland T, Grønseth R, Persson LJ, Aukrust P, Eagan TM.

PLoS One. 2014 Oct 3;9(10):e109721. doi: 10.1371/journal.pone.0109721. eCollection 2014.


Serial Measurements of Arterial Oxygen Tension are Associated with Mortality in COPD.

Aanerud M, Saure EW, Benet M, Basagana X, Bakke PS, Garcia-Aymerich J, Eagan TM, Anto JM, Hardie JA.

COPD. 2015 Jun;12(3):287-94. doi: 10.3109/15412555.2014.948996. Epub 2014 Sep 17.


Inflammatory cytokine response to exercise in alpha-1-antitrypsin deficient COPD patients 'on' or 'off' augmentation therapy.

Olfert IM, Malek MH, Eagan TM, Wagner H, Wagner PD.

BMC Pulm Med. 2014 Jun 30;14:106. doi: 10.1186/1471-2466-14-106.


Predictors for PaO2 and hypoxemic respiratory failure in COPD-A three-year follow-up.

Saure EW, Eagan TM, Jensen RL, Bakke PS, Johannessen A, Aanerud M, Nilsen RM, Thorsen E, Hardie JA.

COPD. 2014 Sep;11(5):531-8. doi: 10.3109/15412555.2014.898027. Epub 2014 May 15.


Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients.

Frisk B, Espehaug B, Hardie JA, Strand LI, Moe-Nilssen R, Eagan TM, Bakke PS, Thorsen E.

Physiol Rep. 2014 Feb 7;2(2):e00222. doi: 10.1002/phy2.222. eCollection 2014 Feb 1.


Paraneoplastic Hu and CRMP5 antibodies are present in smokers without cancer or neurological disease.

Qvale TH, Storstein A, Mazengia K, Eagan TM, Bakke PS, Vedeler CA.

Respirology. 2014 Jul;19(5):730-4. doi: 10.1111/resp.12292. Epub 2014 Apr 3.


The Bergen COPD microbiome study (MicroCOPD): rationale, design, and initial experiences.

Grønseth R, Haaland I, Wiker HG, Martinsen EM, Leiten EO, Husebø G, Svanes Ø, Bakke PS, Eagan TM.

Eur Clin Respir J. 2014 Dec 29;1. doi: 10.3402/ecrj.v1.26196. eCollection 2014.


Insomnia symptoms, objectively measured sleep, and disease severity in chronic obstructive pulmonary disease outpatients.

Hynninen MJ, Pallesen S, Hardie J, Eagan TM, Bjorvatn B, Bakke P, Nordhus IH.

Sleep Med. 2013 Dec;14(12):1328-33. doi: 10.1016/j.sleep.2013.08.785. Epub 2013 Oct 14.


Physical activity and longitudinal change in 6-min walk distance in COPD patients.

Frisk B, Espehaug B, Hardie JA, Strand LI, Moe-Nilssen R, Eagan TM, Bakke PS, Thorsen E.

Respir Med. 2014 Jan;108(1):86-94. doi: 10.1016/j.rmed.2013.09.004. Epub 2013 Sep 13.


Non-response in telephone surveys of COPD patients does not introduce bias.

Aanerud M, Braut H, Wentzel-Larsen T, Eagan TM, Bakke PS.

J Telemed Telecare. 2013 Jan;19(1):40-4. doi: 10.1177/1357633X12474960. Epub 2013 Feb 28.


Reference values for within-breath pulmonary impedance parameters in asymptomatic elderly.

Aarli BB, Eagan TM, Ellingsen I, Bakke PS, Hardie JA.

Clin Respir J. 2013 Jul;7(3):245-52. doi: 10.1111/j.1752-699X.2012.00312.x. Epub 2012 Aug 20.


Chronic obstructive pulmonary disease is associated with low levels of vitamin D.

Persson LJ, Aanerud M, Hiemstra PS, Hardie JA, Bakke PS, Eagan TM.

PLoS One. 2012;7(6):e38934. doi: 10.1371/journal.pone.0038934. Epub 2012 Jun 21.


TNF-α is associated with loss of lean body mass only in already cachectic COPD patients.

Eagan TM, Gabazza EC, D'Alessandro-Gabazza C, Gil-Bernabe P, Aoki S, Hardie JA, Bakke PS, Wagner PD.

Respir Res. 2012 Jun 18;13:48. doi: 10.1186/1465-9921-13-48.


Different COPD disease characteristics are related to different outcomes in the 6-minute walk test.

Waatevik M, Johannessen A, Hardie JA, Bjordal JM, Aukrust P, Bakke PS, Eagan TM.

COPD. 2012 Jun;9(3):227-34. doi: 10.3109/15412555.2011.650240. Epub 2012 Apr 12.


Association of exposure to environmental tobacco smoke in childhood with chronic obstructive pulmonary disease and respiratory symptoms in adults.

Johannessen A, Bakke PS, Hardie JA, Eagan TM.

Respirology. 2012 Apr;17(3):499-505. doi: 10.1111/j.1440-1843.2012.02129.x.


The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway.

Gjerde B, Bakke PS, Ueland T, Hardie JA, Eagan TM.

Respir Med. 2012 Mar;106(3):361-6. doi: 10.1016/j.rmed.2011.10.004. Epub 2011 Nov 29.


Adult attention deficit hyperactivity disorder is associated with asthma.

Fasmer OB, Halmøy A, Eagan TM, Oedegaard KJ, Haavik J.

BMC Psychiatry. 2011 Aug 7;11:128. doi: 10.1186/1471-244X-11-128.


Explained variance for blood gases in a population with COPD.

Saure EW, Eagan TM, Jensen RL, Voll-Aanerud M, Aukrust P, Bakke PS, Hardie JA.

Clin Respir J. 2012 Apr;6(2):72-80. doi: 10.1111/j.1752-699X.2011.00248.x. Epub 2011 Aug 3.


A randomised trial of endobronchial ultrasound guided sampling in peripheral lung lesions.

Roth K, Eagan TM, Andreassen AH, Leh F, Hardie JA.

Lung Cancer. 2011 Nov;74(2):219-25. doi: 10.1016/j.lungcan.2011.02.013. Epub 2011 Apr 11.


High prevalence of respiratory symptoms during air travel in patients with COPD.

Edvardsen A, Akerø A, Hardie JA, Ryg M, Eagan TM, Skjønsberg OH, Bakke PS.

Respir Med. 2011 Jan;105(1):50-6. doi: 10.1016/j.rmed.2010.10.006. Epub 2010 Oct 25.


Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey.

Voll-Aanerud M, Eagan TM, Plana E, Omenaas ER, Bakke PS, Svanes C, Siroux V, Pin I, Antó JM, Leynaert B.

Health Qual Life Outcomes. 2010 Sep 27;8:107. doi: 10.1186/1477-7525-8-107.


Comorbidity of asthma with ADHD.

Fasmer OB, Riise T, Eagan TM, Lund A, Dilsaver SC, Hundal O, Oedegaard KJ.

J Atten Disord. 2011 Oct;15(7):564-71. doi: 10.1177/1087054710372493. Epub 2010 Jun 23.


Neutrophil gelatinase-associated lipocalin: a biomarker in COPD.

Eagan TM, Damås JK, Ueland T, Voll-Aanerud M, Mollnes TE, Hardie JA, Bakke PS, Aukrust P.

Chest. 2010 Oct;138(4):888-95. doi: 10.1378/chest.09-2718. Epub 2010 May 21.


Body composition and plasma levels of inflammatory biomarkers in COPD.

Eagan TM, Aukrust P, Ueland T, Hardie JA, Johannessen A, Mollnes TE, Damås JK, Bakke PS, Wagner PD.

Eur Respir J. 2010 Nov;36(5):1027-33. doi: 10.1183/09031936.00194209. Epub 2010 Apr 22.


Socioeconomic risk factors for lung function decline in a general population.

Johannessen A, Eagan TM, Omenaas ER, Bakke PS, Gulsvik A.

Eur Respir J. 2010 Sep;36(3):480-7. doi: 10.1183/09031936.00186509. Epub 2010 Feb 11.


Quantitative computed tomography measures of emphysema and airway wall thickness are related to respiratory symptoms.

Grydeland TB, Dirksen A, Coxson HO, Eagan TM, Thorsen E, Pillai SG, Sharma S, Eide GE, Gulsvik A, Bakke PS.

Am J Respir Crit Care Med. 2010 Feb 15;181(4):353-9. doi: 10.1164/rccm.200907-1008OC. Epub 2009 Nov 19.


Systemic mannose-binding lectin is not associated with Chronic Obstructive Pulmonary Disease.

Eagan TM, Aukrust P, Bakke PS, Damås JK, Skorge TD, Hardie JA, Ueland T, Mollnes TE.

Respir Med. 2010 Feb;104(2):283-90. doi: 10.1016/j.rmed.2009.09.015.

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