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Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients.

Pitaksalee R, Burska AN, Ajaib S, Rogers J, Parmar R, Mydlova K, Xie X, Droop A, Nijjar JS, Chambers P, Emery P, Hodgett R, McInnes IB, Ponchel F.

Clin Epigenetics. 2020 Apr 7;12(1):54. doi: 10.1186/s13148-020-00837-1.


The effect of ageing on skeletal muscle as assessed by quantitative MR imaging: an association with frailty and muscle strength.

Farrow M, Biglands J, Tanner SF, Clegg A, Brown L, Hensor EMA, O'Connor P, Emery P, Tan AL.

Aging Clin Exp Res. 2020 Mar 20. doi: 10.1007/s40520-020-01530-2. [Epub ahead of print]


Response to "Increased awareness of hypogammaglobulinemia after B-cell targeting therapies" by Karim MY.

Md Yusof MY, Vital EM, Emery P, Savic S.

Arthritis Rheumatol. 2020 Mar 5. doi: 10.1002/art.41244. [Epub ahead of print]


T-cell subset abnormalities predict progression along the Inflammatory Arthritis disease continuum: implications for management.

Ponchel F, Burska AN, Hunt L, Gul H, Rabin T, Parmar R, Buch MH, Conaghan PG, Emery P.

Sci Rep. 2020 Feb 28;10(1):3669. doi: 10.1038/s41598-020-60314-w.


Effect of rituximab or tumour necrosis factor inhibitors on lung infection and survival in rheumatoid arthritis-associated bronchiectasis.

Md Yusof MY, Iqbal K, Darby M, Lettieri G, Vital EM, Beirne P, Dass S, Emery P, Kelly C.

Rheumatology (Oxford). 2020 Feb 17. pii: kez676. doi: 10.1093/rheumatology/kez676. [Epub ahead of print]


Pragmatic randomised controlled trial of very early etanercept and MTX versus MTX with delayed etanercept in RA: the VEDERA trial.

Emery P, Horton S, Dumitru RB, Naraghi K, van der Heijde D, Wakefield RJ, Hensor EMA, Buch MH.

Ann Rheum Dis. 2020 Apr;79(4):464-471. doi: 10.1136/annrheumdis-2019-216539. Epub 2020 Jan 29.


EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update.

Smolen JS, Landewé RBM, Bijlsma JWJ, Burmester GR, Dougados M, Kerschbaumer A, McInnes IB, Sepriano A, van Vollenhoven RF, de Wit M, Aletaha D, Aringer M, Askling J, Balsa A, Boers M, den Broeder AA, Buch MH, Buttgereit F, Caporali R, Cardiel MH, De Cock D, Codreanu C, Cutolo M, Edwards CJ, van Eijk-Hustings Y, Emery P, Finckh A, Gossec L, Gottenberg JE, Hetland ML, Huizinga TWJ, Koloumas M, Li Z, Mariette X, Müller-Ladner U, Mysler EF, da Silva JAP, Poór G, Pope JE, Rubbert-Roth A, Ruyssen-Witrand A, Saag KG, Strangfeld A, Takeuchi T, Voshaar M, Westhovens R, van der Heijde D.

Ann Rheum Dis. 2020 Jan 22. pii: annrheumdis-2019-216655. doi: 10.1136/annrheumdis-2019-216655. [Epub ahead of print]


Pooled analysis of TNF inhibitor biosimilar studies comparing radiographic progression by disease activity states in rheumatoid arthritis.

Smolen JS, Choe JY, Weinblatt ME, Emery P, Keystone E, Genovese MC, Myung G, Hong E, Baek I, Ghil J.

RMD Open. 2020 Jan;6(1). pii: e001096. doi: 10.1136/rmdopen-2019-001096.


Prevention and cure: The major unmet needs in the management of rheumatoid arthritis.

Mankia K, Di Matteo A, Emery P.

J Autoimmun. 2019 Dec 30:102399. doi: 10.1016/j.jaut.2019.102399. [Epub ahead of print]


B Cell Tetherin: A Flow Cytometric Cell-Specific Assay for Response to Type I Interferon Predicts Clinical Features and Flares in Systemic Lupus Erythematosus.

El-Sherbiny YM, Md Yusof MY, Psarras A, Hensor EMA, Kabba KZ, Dutton K, Mohamed AAA, Elewaut D, McGonagle D, Tooze R, Doody G, Wittmann M, Emery P, Vital EM.

Arthritis Rheumatol. 2019 Dec 5. doi: 10.1002/art.41187. [Epub ahead of print]


How Are Rheumatologists Managing Anticyclic Citrullinated Peptide Antibodies-positive Patients Who Do Not Have Arthritis?

Mankia K, Briggs C, Emery P.

J Rheumatol. 2020 Feb;47(2):305-306. doi: 10.3899/jrheum.190211. Epub 2019 Dec 1. No abstract available.


Risk of Malignancies in Patients with Rheumatoid Arthritis Treated with Rituximab: Analyses of Global Postmarketing Safety Data and Long-Term Clinical Trial Data.

Emery P, Furst DE, Kirchner P, Melega S, Lacey S, Lehane PB.

Rheumatol Ther. 2020 Mar;7(1):121-131. doi: 10.1007/s40744-019-00183-6. Epub 2019 Nov 21.


Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing.

Foley LE, Ling J, Joshi R, Evantal N, Kadener S, Emery P.

Elife. 2019 Nov 8;8. pii: e50063. doi: 10.7554/eLife.50063.


Comparing psoriatic arthritis low-field magnetic resonance imaging, ultrasound and clinical outcomes: data from the TICOPA trial.

Helliwell PS, Coates LC, Chew NS, Lettieri G, Moverley AR, Freeston JE, Nam J, Waxman R, Emery P, Conaghan PG.

J Rheumatol. 2019 Nov 1. pii: jrheum.181385. doi: 10.3899/jrheum.181385. [Epub ahead of print]


Drosophila Cryptochrome: Variations in Blue.

Foley LE, Emery P.

J Biol Rhythms. 2020 Feb;35(1):16-27. doi: 10.1177/0748730419878290. Epub 2019 Oct 10.


Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.

Traylor M, Knevel R, Cui J, Taylor J, Harm-Jan W, Conaghan PG, Cope AP, Curtis C, Emery P, Newhouse S, Patel H, Steer S, Gregersen P, Shadick NA, Weinblatt ME, Van Der Helm-van Mil A, Barrett JH, Morgan AW, Lewis CM, Scott IC.

PLoS One. 2019 Oct 9;14(10):e0223246. doi: 10.1371/journal.pone.0223246. eCollection 2019.


Palindromic rheumatism as part of the rheumatoid arthritis continuum.

Mankia K, Emery P.

Nat Rev Rheumatol. 2019 Nov;15(11):687-695. doi: 10.1038/s41584-019-0308-5. Epub 2019 Oct 8. Review.


A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial.

Mease PJ, Smolen JS, Behrens F, Nash P, Liu Leage S, Li L, Tahir H, Gooderham M, Krishnan E, Liu-Seifert H, Emery P, Pillai SG, Helliwell PS; SPIRIT H2H study group.

Ann Rheum Dis. 2020 Jan;79(1):123-131. doi: 10.1136/annrheumdis-2019-215386. Epub 2019 Sep 28.


Baseline Objective Inflammation by Magnetic Resonance Imaging as a Predictor of Therapeutic Benefit in Early, Poor Prognosis Rheumatoid Arthritis.

Ahmad HA, Baker JF, Østergaard M, Emery P, Durez P, Ye J, Banerjee S, Conaghan PG.

Arthritis Care Res (Hoboken). 2019 Sep 24. doi: 10.1002/acr.24072. [Epub ahead of print]


Validity and sensitivity to change of laser Doppler imaging as a novel objective outcome measure for cutaneous lupus erythematosus.

Md Yusof MY, Britton J, Edward S, Hensor EMA, Goodfield MJ, Laws PM, Emery P, Wittmann M, Vital EM.

Lupus. 2019 Oct;28(11):1320-1328. doi: 10.1177/0961203319873977. Epub 2019 Sep 14.


Long-term follow-up of patients in the TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) trial.

Coates LC, Mahmood F, Freeston J, Emery P, Conaghan PG, Helliwell PS.

Rheumatology (Oxford). 2020 Apr 1;59(4):807-810. doi: 10.1093/rheumatology/kez369.


Defining remission in rheumatoid arthritis: does it matter to the patient? A comparison of multi-dimensional remission criteria and patient reported outcomes.

Gul HL, Eugenio G, Rabin T, Burska A, Parmar R, Wu J, Ponchel F, Emery P.

Rheumatology (Oxford). 2020 Mar 1;59(3):613-621. doi: 10.1093/rheumatology/kez330.


Reduction in stiffness of proximal leg muscles during the first 6 months of glucocorticoid therapy for giant cell arteritis: A pilot study using shear wave elastography.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Mackie S, Wakefield RJ.

Int J Rheum Dis. 2019 Oct;22(10):1891-1899. doi: 10.1111/1756-185X.13667. Epub 2019 Jul 30.


IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function.

Ridgley LA, Anderson AE, Maney NJ, Naamane N, Skelton AJ, Lawson CA, Emery P, Isaacs JD, Carmody RJ, Pratt AG.

Front Immunol. 2019 Jul 3;10:1535. doi: 10.3389/fimmu.2019.01535. eCollection 2019.


Improvement in cardiovascular biomarkers sustained at 4 years following an initial treat-to-target strategy in early rheumatoid arthritis.

Mortimer I, Bissell LA, Hensor EMA, Kozera L, Mackie SL, Burska AN, Nam JL, Keen H, Villeneuve E, Donica H, Buch MH, Conaghan PG, Emery P, Morgan AW, Andrews J.

Rheumatology (Oxford). 2019 Sep 1;58(9):1684-1686. doi: 10.1093/rheumatology/kez114. No abstract available.


Muscle stiffness in rheumatoid arthritis is not altered or associated with muscle weakness: A shear wave elastography study.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Mod Rheumatol. 2019 Aug 1:1-9. doi: 10.1080/14397595.2019.1645374. [Epub ahead of print]


Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol.

Al-Laith M, Jasenecova M, Abraham S, Bosworth A, Bruce IN, Buckley CD, Ciurtin C, D'Agostino MA, Emery P, Gaston H, Isaacs JD, Filer A, Fisher BA, Huizinga TWJ, Ho P, Jacklin C, Lempp H, McInnes IB, Pratt AG, Östor A, Raza K, Taylor PC, van Schaardenburg D, Shivapatham D, Wright AJ, Vasconcelos JC, Kelly J, Murphy C, Prevost AT, Cope AP.

Trials. 2019 Jul 15;20(1):429. doi: 10.1186/s13063-019-3403-7.


Normal values and test-retest variability of stimulated-echo diffusion tensor imaging and fat fraction measurements in the muscle.

Farrow M, Grainger AJ, Tan AL, Buch MH, Emery P, Ridgway JP, Feiweier T, Tanner SF, Biglands J.

Br J Radiol. 2019 Sep;92(1101):20190143. doi: 10.1259/bjr.20190143. Epub 2019 Jul 12.


Determining MRI Inflammation Targets When Considering a Rheumatoid Arthritis Treat-to-Target Strategy: Results of a Randomized, Placebo-Controlled Trial.

Ahmad HA, Baker JF, Østergaard M, Ye J, Emery P, Conaghan PG.

Adv Ther. 2019 Sep;36(9):2384-2393. doi: 10.1007/s12325-019-01020-6. Epub 2019 Jul 5.


The effect of deep or sustained remission on maintenance of remission after dose reduction or withdrawal of etanercept in patients with rheumatoid arthritis.

Tanaka Y, Smolen JS, Jones H, Szumski A, Marshall L, Emery P.

Arthritis Res Ther. 2019 Jul 5;21(1):164. doi: 10.1186/s13075-019-1937-4.


Relative Impact of Pain and Fatigue on Work Productivity in Patients with Rheumatoid Arthritis from the RA-BEAM Baricitinib Trial.

Michaud K, Pope JE, Emery P, Zhu B, Gaich CL, DeLozier AM, Zhang X, Dickson CL, Smolen JS.

Rheumatol Ther. 2019 Sep;6(3):409-419. doi: 10.1007/s40744-019-0164-4. Epub 2019 Jun 21.


Achieving Pain Control in Rheumatoid Arthritis with Baricitinib or Adalimumab Plus Methotrexate: Results from the RA-BEAM Trial.

Taylor PC, Lee YC, Fleischmann R, Takeuchi T, Perkins EL, Fautrel B, Zhu B, Quebe AK, Gaich CL, Zhang X, Dickson CL, Schlichting DE, Patel H, Durand F, Emery P.

J Clin Med. 2019 Jun 12;8(6). pii: E831. doi: 10.3390/jcm8060831.


Prevalence of Periodontal Disease and Periodontopathic Bacteria in Anti-Cyclic Citrullinated Protein Antibody-Positive At-Risk Adults Without Arthritis.

Mankia K, Cheng Z, Do T, Hunt L, Meade J, Kang J, Clerehugh V, Speirs A, Tugnait A, Hensor EMA, Nam JL, Devine DA, Emery P.

JAMA Netw Open. 2019 Jun 5;2(6):e195394. doi: 10.1001/jamanetworkopen.2019.5394.


Low rates of radiographic progression of structural joint damage over 2 years of baricitinib treatment in patients with rheumatoid arthritis.

van der Heijde D, Schiff M, Tanaka Y, Xie L, Meszaros G, Ishii T, Casillas M, Ortmann RA, Emery P.

RMD Open. 2019 May 10;5(1):e000898. doi: 10.1136/rmdopen-2019-000898. eCollection 2019. Erratum in: RMD Open. 2019 Jul 8;5(2):e000898corr1.


Pain and depression are associated with both physical and mental fatigue independently of comorbidities and medications in primary Sjögren's syndrome.

Hackett KL, Davies K, Tarn J, Bragg R, Hargreaves B, Miyamoto S, McMeekin P, Mitchell S, Bowman S, Price EJ, Pease C, Emery P, Andrews J, Lanyon P, Hunter J, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Vadivelu S, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B, Lendrem DW, Ng WF.

RMD Open. 2019 Apr 24;5(1):e000885. doi: 10.1136/rmdopen-2018-000885. eCollection 2019.


Longterm Drug Survival of Tumor Necrosis Factor Inhibitors in Patients with Rheumatoid Arthritis.

Emery P, Vlahos B, Szczypa P, Thakur M, Jones HE, Woolcott J, Santos Estrella PV, Rolland C, Gibofsky A, Citera G, Sockalingam S, Marshall L.

J Rheumatol. 2020 Apr;47(4):493-501. doi: 10.3899/jrheum.181398. Epub 2019 Jun 1.


Predicting Severe Infection and Effects of Hypogammaglobulinemia During Therapy With Rituximab in Rheumatic and Musculoskeletal Diseases.

Md Yusof MY, Vital EM, McElvenny DM, Hensor EMA, Das S, Dass S, Rawstron AC, Buch MH, Emery P, Savic S.

Arthritis Rheumatol. 2019 Nov;71(11):1812-1823. doi: 10.1002/art.40937. Epub 2019 Sep 26.


Upadacitinib as monotherapy in patients with active rheumatoid arthritis and inadequate response to methotrexate (SELECT-MONOTHERAPY): a randomised, placebo-controlled, double-blind phase 3 study.

Smolen JS, Pangan AL, Emery P, Rigby W, Tanaka Y, Vargas JI, Zhang Y, Damjanov N, Friedman A, Othman AA, Camp HS, Cohen S.

Lancet. 2019 Jun 8;393(10188):2303-2311. doi: 10.1016/S0140-6736(19)30419-2. Epub 2019 May 23. Erratum in: Lancet. 2019 Jun 29;393(10191):2590.


Response to: 'Interosseous tendon inflammation of rheumatoid arthritis: what's the real meaning?' by Deng et al.

Mankia K, D'Agostino MA, Murillo-González J, Grainger A, Emery P.

Ann Rheum Dis. 2019 May 17. pii: annrheumdis-2019-215611. doi: 10.1136/annrheumdis-2019-215611. [Epub ahead of print] No abstract available.


Quantifying circulating Th17 cells by qPCR: potential as diagnostic biomarker for rheumatoid arthritis.

Burska AN, Thu A, Parmar R, Bzoma I, Samans B, Raschke E, Olek S, Conaghan PG, Emery P, Ponchel F.

Rheumatology (Oxford). 2019 Nov 1;58(11):2015-2024. doi: 10.1093/rheumatology/kez162.


Re-treatment with abatacept plus methotrexate for disease flare after complete treatment withdrawal in patients with early rheumatoid arthritis: 2-year results from the AVERT study.

Emery P, Burmester GR, Bykerk VP, Combe BG, Furst DE, Maldonado MA, Huizinga TW.

RMD Open. 2019 Feb 8;5(1):e000840. doi: 10.1136/rmdopen-2018-000840. eCollection 2019.


Nutrient, fibre, sorbitol and chlorogenic acid content of prunes (Prunus domestica): an updated analysis and comparison of different countries of origin and database values.

Gill SK, Lever E, Emery PW, Whelan K.

Int J Food Sci Nutr. 2019 Dec;70(8):924-931. doi: 10.1080/09637486.2019.1600664. Epub 2019 Apr 16.


MRI inflammation of the hand interosseous tendons occurs in anti-CCP-positive at-risk individuals and may precede the development of clinical synovitis.

Mankia K, D'Agostino MA, Rowbotham E, Hensor EM, Hunt L, Möller I, Miguel M, Mérida-Velasco JR, Murillo-González J, Naredo E, Nam JL, Tan AL, Freeston JE, Grainger A, Emery P.

Ann Rheum Dis. 2019 Jun;78(6):781-786. doi: 10.1136/annrheumdis-2018-214331. Epub 2019 Mar 23.


First cardiovascular MRI study in individuals at risk of rheumatoid arthritis detects abnormal aortic stiffness suggesting an anti-citrullinated peptide antibody-mediated role for accelerated atherosclerosis.

Fent G, Mankia K, Erhayiem B, Hunt L, Nam JL, Bissell LA, Foley JR, Chew PG, Brown LE, Greenwood JP, Emery P, Plein S, Buch MH.

Ann Rheum Dis. 2019 Aug;78(8):1138-1140. doi: 10.1136/annrheumdis-2018-214975. Epub 2019 Mar 9. No abstract available.


Evolving treatment paradigms for rheumatoid arthritis: Translating comprehensive patient evaluations into personalized therapy.

Calabrese LH, Emery P, Kivitz AJ, Tesser JRP.

Semin Arthritis Rheum. 2019 Jan 23. pii: S0049-0172(19)30030-7. doi: 10.1016/j.semarthrit.2019.01.008. [Epub ahead of print] No abstract available.


Validity of a two-component imaging-derived disease activity score for improved assessment of synovitis in early rheumatoid arthritis.

Hensor EMA, McKeigue P, Ling SF, Colombo M, Barrett JH, Nam JL, Freeston J, Buch MH, Spiliopoulou A, Agakov F, Kelly S, Lewis MJ, Verstappen SMM, MacGregor AJ, Viatte S, Barton A, Pitzalis C, Emery P, Conaghan PG, Morgan AW.

Rheumatology (Oxford). 2019 Mar 1. pii: kez049. doi: 10.1093/rheumatology/kez049. [Epub ahead of print]


Muscle shear wave elastography in idiopathic inflammatory myopathies: a case-control study with MRI correlation.

Alfuraih AM, O'Connor P, Tan AL, Hensor EMA, Ladas A, Emery P, Wakefield RJ.

Skeletal Radiol. 2019 Aug;48(8):1209-1219. doi: 10.1007/s00256-019-03175-3. Epub 2019 Feb 27.


The effect of ageing on shear wave elastography muscle stiffness in adults.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Aging Clin Exp Res. 2019 Dec;31(12):1755-1763. doi: 10.1007/s40520-019-01139-0. Epub 2019 Feb 14.


Correction to: On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis.

Bykerk VP, Burmester GR, Combe BG, Furst DE, Huizinga TWJ, Ahmad HA, Emery P.

Rheumatol Int. 2019 May;39(5):945. doi: 10.1007/s00296-018-4232-9.


Clinical trial and 'real-world' data support switching from a bio-originator to its biosimilar.

Kay J, Dörner T, Emery P, Kvien TK, Breedveld FC.

Ann Rheum Dis. 2020 Apr;79(4):e44. doi: 10.1136/annrheumdis-2018-214994. Epub 2019 Jan 18. No abstract available.

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