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Items: 24

1.

Long-Term Colonization Dynamics of Enterococcus faecalis in Implanted Devices in Research Macaques.

Lieberman MT, Van Tyne D, Dzink-Fox J, Ma EJ, Gilmore MS, Fox JG.

Appl Environ Microbiol. 2018 Aug 31;84(18). pii: e01336-18. doi: 10.1128/AEM.01336-18. Print 2018 Sep 15.

2.

Plasmid-Mediated Quinolone Resistance in Shigella flexneri Isolated From Macaques.

Mannion AJ, Martin HR, Shen Z, Buckley EM, Dzink-Fox JL, Garcia A, Marini RP, Patterson MM, Fox JG.

Front Microbiol. 2018 Mar 5;9:311. doi: 10.3389/fmicb.2018.00311. eCollection 2018.

3.

Isolation and molecular characterization of group B Streptococcus from laboratory Long-Evans rats (Rattus norvegicus) with and without invasive group B streptococcal disease.

Bodi Winn C, Bakthavatchalu V, Esmail MY, Feng Y, Dzink-Fox J, Richey L, Perkins SE, Nordberg EK, Fox JG.

J Med Microbiol. 2017 Nov 21. doi: 10.1099/jmm.0.000627. [Epub ahead of print]

4.

Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.

Piizzi G, Parker DT, Peng Y, Dobler M, Patnaik A, Wattanasin S, Liu E, Lenoir F, Nunez J, Kerrigan J, McKenney D, Osborne C, Yu D, Lanieri L, Bojkovic J, Dzink-Fox J, Lilly MD, Sprague ER, Lu Y, Wang H, Ranjitkar S, Xie L, Wang B, Glick M, Hamann LG, Tommasi R, Yang X, Dean CR.

J Med Chem. 2017 Jun 22;60(12):5002-5014. doi: 10.1021/acs.jmedchem.7b00377. Epub 2017 Jun 9.

PMID:
28549219
5.

Characterization of Multi-Drug Resistant Enterococcus faecalis Isolated from Cephalic Recording Chambers in Research Macaques (Macaca spp.).

Woods SE, Lieberman MT, Lebreton F, Trowel E, de la Fuente-Núñez C, Dzink-Fox J, Gilmore MS, Fox JG.

PLoS One. 2017 Jan 12;12(1):e0169293. doi: 10.1371/journal.pone.0169293. eCollection 2017.

6.

Whole-Genome Sequences and Classification of Streptococcus agalactiae Strains Isolated from Laboratory-Reared Long-Evans Rats (Rattus norvegicus).

Bodi Winn C, Dzink-Fox J, Feng Y, Shen Z, Bakthavatchalu V, Fox JG.

Genome Announc. 2017 Jan 5;5(1). pii: e01435-16. doi: 10.1128/genomeA.01435-16.

7.

Changes in the antibiotic susceptibility of anaerobic bacteria from 2007-2009 to 2010-2012 based on the CLSI methodology.

Hastey CJ, Boyd H, Schuetz AN, Anderson K, Citron DM, Dzink-Fox J, Hackel M, Hecht DW, Jacobus NV, Jenkins SG, Karlsson M, Knapp CC, Koeth LM, Wexler H, Roe-Carpenter DE; From the Ad Hoc Working Group on Antimicrobial Susceptibility Testing of Anaerobic Bacteria of CLSI.

Anaerobe. 2016 Dec;42:27-30. doi: 10.1016/j.anaerobe.2016.07.003. Epub 2016 Jul 15.

PMID:
27427465
8.

Antibacterial and Solubility Optimization of Thiomuracin A.

LaMarche MJ, Leeds JA, Brewer J, Dean K, Ding J, Dzink-Fox J, Gamber G, Jain A, Kerrigan R, Krastel P, Lee K, Lombardo F, McKenney D, Neckermann G, Osborne C, Palestrant D, Patane MA, Rann EM, Robinson Z, Schmitt E, Stams T, Tiamfook S, Yu D, Whitehead L.

J Med Chem. 2016 Jul 28;59(14):6920-8. doi: 10.1021/acs.jmedchem.6b00726. Epub 2016 Jul 12.

PMID:
27355833
9.

Antibiotic optimization and chemical structure stabilization of thiomuracin A.

LaMarche MJ, Leeds JA, Dzink-Fox J, Gangl E, Krastel P, Neckermann G, Palestrant D, Patane MA, Rann EM, Tiamfook S, Yu D.

J Med Chem. 2012 Aug 9;55(15):6934-41. doi: 10.1021/jm300783c. Epub 2012 Jul 31.

PMID:
22812377
10.

Mechanism of action of and mechanism of reduced susceptibility to the novel anti-Clostridium difficile compound LFF571.

Leeds JA, Sachdeva M, Mullin S, Dzink-Fox J, Lamarche MJ.

Antimicrob Agents Chemother. 2012 Aug;56(8):4463-5. doi: 10.1128/AAC.06354-11. Epub 2012 May 29.

11.

Discovery of LFF571: an investigational agent for Clostridium difficile infection.

LaMarche MJ, Leeds JA, Amaral A, Brewer JT, Bushell SM, Deng G, Dewhurst JM, Ding J, Dzink-Fox J, Gamber G, Jain A, Lee K, Lee L, Lister T, McKenney D, Mullin S, Osborne C, Palestrant D, Patane MA, Rann EM, Sachdeva M, Shao J, Tiamfook S, Trzasko A, Whitehead L, Yifru A, Yu D, Yan W, Zhu Q.

J Med Chem. 2012 Mar 8;55(5):2376-87. doi: 10.1021/jm201685h. Epub 2012 Feb 23.

PMID:
22315981
12.

Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.

LaMarche MJ, Leeds JA, Amaral K, Brewer JT, Bushell SM, Dewhurst JM, Dzink-Fox J, Gangl E, Goldovitz J, Jain A, Mullin S, Neckermann G, Osborne C, Palestrant D, Patane MA, Rann EM, Sachdeva M, Shao J, Tiamfook S, Whitehead L, Yu D.

J Med Chem. 2011 Dec 8;54(23):8099-109. doi: 10.1021/jm200938f. Epub 2011 Nov 1.

PMID:
21999529
13.

In vitro and in vivo activities of novel, semisynthetic thiopeptide inhibitors of bacterial elongation factor Tu.

Leeds JA, LaMarche MJ, Brewer JT, Bushell SM, Deng G, Dewhurst JM, Dzink-Fox J, Gangl E, Jain A, Lee L, Lilly M, Manni K, Mullin S, Neckermann G, Osborne C, Palestrant D, Patane MA, Raimondi A, Ranjitkar S, Rann EM, Sachdeva M, Shao J, Tiamfook S, Whitehead L, Yu D.

Antimicrob Agents Chemother. 2011 Nov;55(11):5277-83. doi: 10.1128/AAC.00582-11. Epub 2011 Aug 8.

14.

4-Aminothiazolyl analogs of GE2270 A: design, synthesis and evaluation of imidazole analogs.

LaMarche MJ, Leeds JA, Dzink-Fox J, Mullin S, Patane MA, Rann EM, Tiamfook S.

Bioorg Med Chem Lett. 2011 Jun 1;21(11):3210-5. doi: 10.1016/j.bmcl.2011.04.048. Epub 2011 Apr 21.

PMID:
21550238
15.

4-Aminothiazolyl analogues of GE2270 A: antibacterial lead finding.

LaMarche MJ, Leeds JA, Dzink-Fox J, Gunderson K, Krastel P, Memmert K, Patane MA, Rann EM, Schmitt E, Tiamfook S, Wang B.

J Med Chem. 2011 Apr 14;54(7):2517-21. doi: 10.1021/jm101602q. Epub 2011 Mar 15.

PMID:
21405087
16.

Direct bacterial killing in vitro by recombinant Nod2 is compromised by Crohn's disease-associated mutations.

Perez LH, Butler M, Creasey T, Dzink-Fox J, Gounarides J, Petit S, Ropenga A, Ryder N, Smith K, Smith P, Parkinson SJ.

PLoS One. 2010 Jun 1;5(6):e10915. doi: 10.1371/journal.pone.0010915.

17.

Fmt bypass in Pseudomonas aeruginosa causes induction of MexXY efflux pump expression.

Caughlan RE, Sriram S, Daigle DM, Woods AL, Buco J, Peterson RL, Dzink-Fox J, Walker S, Dean CR.

Antimicrob Agents Chemother. 2009 Dec;53(12):5015-21. doi: 10.1128/AAC.00253-09. Epub 2009 Sep 28.

18.

In vivo characterization of the peptide deformylase inhibitor LBM415 in murine infection models.

Osborne CS, Neckermann G, Fischer E, Pecanka R, Yu D, Manni K, Goldovitz J, Amaral K, Dzink-Fox J, Ryder NS.

Antimicrob Agents Chemother. 2009 Sep;53(9):3777-81. doi: 10.1128/AAC.00026-09. Epub 2009 Jul 13.

19.

Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones.

Peukert S, Sun Y, Zhang R, Hurley B, Sabio M, Shen X, Gray C, Dzink-Fox J, Tao J, Cebula R, Wattanasin S.

Bioorg Med Chem Lett. 2008 Mar 15;18(6):1840-4. doi: 10.1016/j.bmcl.2008.02.009. Epub 2008 Feb 10.

PMID:
18295483
20.

The marC gene of Escherichia coli is not involved in multiple antibiotic resistance.

McDermott PF, McMurry LM, Podglajen I, Dzink-Fox JL, Schneiders T, Draper MP, Levy SB.

Antimicrob Agents Chemother. 2008 Jan;52(1):382-3. Epub 2007 Oct 22. No abstract available.

21.

Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number.

Dean CR, Narayan S, Richards J, Daigle DM, Esterow S, Leeds JA, Kamp H, Puyang X, Wiedmann B, Mueller D, Voshol H, van Oostrum J, Wall D, Koehn J, Dzink-Fox J, Ryder NS.

Antimicrob Agents Chemother. 2007 Mar;51(3):1004-10. Epub 2007 Jan 12.

22.

Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415.

Dean CR, Narayan S, Daigle DM, Dzink-Fox JL, Puyang X, Bracken KR, Dean KE, Weidmann B, Yuan Z, Jain R, Ryder NS.

Antimicrob Agents Chemother. 2005 Aug;49(8):3129-35.

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